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M. thermoresistible (build 8) TH_4080 (-)

annotation: conserved hypothetical protein
coordinates: 3570290 - 3571804
length: 505

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4080--100% (505)conserved hypothetical protein
M. thermoresistible (build 8)TH_3452-7e-8032.02% (481) PUTATIVE lipolytic enzyme
M. thermoresistible (build 8)TH_2696-6e-7834.17% (480) PUTATIVE putative FAD dependent oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3075c-0.074.95% (507) monooxygenase
M. gilvum PYR-GCKMflv_4287-0.069.35% (509) putative monooxygenase
M. tuberculosis H37RvRv3049c-0.074.95% (507) monooxygenase
M. leprae Br4923MLBr_00065-5e-3427.99% (393) putative monooxygenase
M. abscessus ATCC 19977MAB_3920c-0.060.43% (508) monooxygenase
M. marinum MMMAR_1644-0.071.97% (503) monooxygenase
M. avium 104MAV_3915-0.073.31% (502) flavin-containing monooxygenase FMO
M. smegmatis MC2 155MSMEG_2310-0.071.13% (485) monooxygenase
M. ulcerans Agy99MUL_1880-0.071.77% (503) monooxygenase
M. vanbaalenii PYR-1Mvan_2059-0.068.76% (509) putative monooxygenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3075c|M.bovis_AF2122/97           ---MSIADTAAKPSTP----SPANQPPVRTRAVIIGTGFSGLGMAIALQK
Rv3049c|M.tuberculosis_H37Rv        ---MSIADTAAKPSTP----SPANQPPVRTRAVIIGTGFSGLGMAIALQK
MMAR_1644|M.marinum_M               MTDVVIPSTETTASGE----PQAPTPPVKTRAVIIGTGFSGLGMAIALQK
MUL_1880|M.ulcerans_Agy99           MTDVVIPSTETTASGE----PQAPTPPVKTRAVIIGTGFSGLGMAIALQK
MAV_3915|M.avium_104                MTDVVT-HTETAPTPA----AKAAKP-VHTRAVIIGTGFSGLGMAIALQK
TH_4080|M.thermoresistible__bu      ---MTVTEPSADITPA----NTPTQPPVRTRALIVGTGFSGLGMAIALQR
Mflv_4287|M.gilvum_PYR-GCK          -------MTVAESADT----TAPPQTPVRTRTLIIGSGFSGLGMAIELQR
Mvan_2059|M.vanbaalenii_PYR-1       -------MTVAEQADL----TSAGQTPVRTRALIIGSGFSGLGMGIELQR
MSMEG_2310|M.smegmatis_MC2_155      ---------------M----TAADQQPIRTRALVIGTGFSGLGMAIELQR
MAB_3920c|M.abscessus_ATCC_199      ---MTVTETSHEEQRPDTVGDGGSSEPIRIRALIVGTGFSGIGAGIALQK
MLBr_00065|M.leprae_Br4923          --------------------MVVMAETEYLDVVIVGAGISGVSAAWHLQD
                                                                   .:::*:*:**:. .  ** 

Mb3075c|M.bovis_AF2122/97           QG--VDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHL
Rv3049c|M.tuberculosis_H37Rv        QG--VDFVILEKADDVGGTWRDNTYPGCACDIPSHLYSFSFEPKADWKHL
MMAR_1644|M.marinum_M               QG--VDFVILEKSDDVGGTWRDNSYPGCACDIPSHLYSFSFEPKPDWRNP
MUL_1880|M.ulcerans_Agy99           QG--VDFVILEKSDDVGGTWRDNSYPGCACDIPSHLYSFSFEPKPDWRNP
MAV_3915|M.avium_104                QG--VGFVILEKADDIGGTWRDNSYPGCACDIPSHLYSFSFEPKPDWKNP
TH_4080|M.thermoresistible__bu      RG--IDFLMLEKADDIGGTWRDNTYPGCACDIPSHLYSFSFEPKADWRHL
Mflv_4287|M.gilvum_PYR-GCK          RG--VDFLILEKSDEIGGTWRDNTYPGCACDIPSHMYSFSFEPKADWSHM
Mvan_2059|M.vanbaalenii_PYR-1       RG--VDFLILEKADEIGGTWRDNTYPGCACDIPSHMYSFSFEPKPDWTHM
MSMEG_2310|M.smegmatis_MC2_155      RG--VDFLILEKADEIGGTWRDNTYPGCACDIPSHMYSFSFEPKADWKHM
MAB_3920c|M.abscessus_ATCC_199      MG--VPFHILEKAGEMGGTWRDNTYPGAACDVPTHLYSFSFEPRSTWDRL
MLBr_00065|M.leprae_Br4923          RCPNKSYVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRPWTKCQAI
                                          : :***   :****    ***  .*   :  .* *.* .     

Mb3075c|M.bovis_AF2122/97           FSYWDEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADG-
Rv3049c|M.tuberculosis_H37Rv        FSYWDEILGYLKGVTDKYGLRRYIEFNSLVDRGYWDDDECRWHVFTADG-
MMAR_1644|M.marinum_M               FSYQPEIWDYLKGVTEKYGLRRYVEFNSLVDRAYWDDEECRWHVFTSDG-
MUL_1880|M.ulcerans_Agy99           FSYQPEIWDYLKGVTEKYGLRRYVEFNSLVDRAYWDDEECRWHVFTSDG-
MAV_3915|M.avium_104                FSYQPEIWDYLKGVTEKYGLRRYIEFNSLVDRAHWDDDEHRWHVFTTDG-
TH_4080|M.thermoresistible__bu      FSYQDEIQEYLQGVTAKYGLRRYIHFDSLVDRAHWDDTEHRWHVFTADG-
Mflv_4287|M.gilvum_PYR-GCK          WSFQPEIQEYLLGVTAKYGLRRYIEFGAHVDRAHWDDAEMRWHVFTKDG-
Mvan_2059|M.vanbaalenii_PYR-1       WSFQPEIQDYLLGVTAKYGLRRYVEFGAHVDRALWDDDEMRWHVHTKDG-
MSMEG_2310|M.smegmatis_MC2_155      WSFQPEIQDYLLGVTAKYGLRRHIHFNSHVDRAHWDDEELRWHVFTKTG-
MAB_3920c|M.abscessus_ATCC_199      FSQQPEIFDYLKEVGAKYGLYRHVTFNTRVTRGYWDEDEYRWHVFTDGG-
MLBr_00065|M.leprae_Br4923          ADGKP-ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNG
                                     .    *  *:  .   :*: ::: :.  *  . *.. * ** * .  . 

Mb3075c|M.bovis_AF2122/97           --REYVAQFLISGAGALHIPS--FPEIAGRDEFAG---PAFHSAQWDHSI
Rv3049c|M.tuberculosis_H37Rv        --REYVAQFLISGAGALHIPS--FPEIAGRDEFAG---PAFHSAQWDHSI
MMAR_1644|M.marinum_M               --REYVAQFLISGAGALHIPS--LPEIEGREEFAG---PAFHSAEWDHSV
MUL_1880|M.ulcerans_Agy99           --REYVAQFLISGAGALHIPS--SPEIEGREEFAG---PAFHSAEWDHSV
MAV_3915|M.avium_104                --REYVAQFLISGAGALHIPS--LPDIEGRDEFAG---PAFHSAEWDHTV
TH_4080|M.thermoresistible__bu      --REYIAQFLISCAGALHIPS--IPDFPGRDQFAG---PAFHSAQWDHSV
Mflv_4287|M.gilvum_PYR-GCK          --REFIAQFLVSGAGGLHIPL--IPEFEGYDDFLASGRAAFHSAQWDHSV
Mvan_2059|M.vanbaalenii_PYR-1       --REFIAQFLISGAGGLHIPL--IPEFDGYDEYLAAGRVAFHSAQWDHDV
MSMEG_2310|M.smegmatis_MC2_155      --QEYIAQFLVSGAGGLHIPQ--IPDIEGRESFAG---AAFHSAQWDHSV
MAB_3920c|M.abscessus_ATCC_199      --QEYICQFLISGVGALHIPS--IPEIEGLDRFEG---PVFHSAQWNHDY
MLBr_00065|M.leprae_Br4923          TPRMISCSFLFLCSGYYNYEQGYAPTFLGSEDFTG---PIIHPQHWPEDL
                                      :   ..**.   *  :      * : * : : .     :*. .* .  

Mb3075c|M.bovis_AF2122/97           DLTGKRVAIVGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRTNEELP
Rv3049c|M.tuberculosis_H37Rv        DLTGKRVAIVGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRTNEELP
MMAR_1644|M.marinum_M               DLTGKRVAIIGTGASAIQIVPEIVEQ-VGELQLYQRTPPWVVPRSNPEIP
MUL_1880|M.ulcerans_Agy99           DLTGKRVAIIGAGASAIQIVPEIVEQ-VGELQLYQRTPPWVVPRSNPEIP
MAV_3915|M.avium_104                DLTGKRVAVIGTGASAIQIVPEIVGQ-VAELQLYQRTPPWVVPRSNPEIP
TH_4080|M.thermoresistible__bu      DLTGKRVAVIGTGASAIQIVPEIIDR-VAQLQLYQRTPAWVVPRTNDELP
Mflv_4287|M.gilvum_PYR-GCK          DIAGKKVAVIGTGASAIQIVPEIVED-VAELQLYQRTPAWVMPRPNNPIP
Mvan_2059|M.vanbaalenii_PYR-1       DITGKKVAVIGTGASAIQIVPEIVKD-VDELQLYQRTPAWVMPRPNNPIP
MSMEG_2310|M.smegmatis_MC2_155      DLRGKRVAVIGTGASAIQIVPEIVKD-VAELHLYQRTPAWVMPRVNNAFP
MAB_3920c|M.abscessus_ATCC_199      DLTGKKVAVIGTGASAIQFVPEIVGK-VGELKLFQRTPPWVLPRTNVEFG
MLBr_00065|M.leprae_Br4923          DYAAKNIVVIGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKI
                                    *  .*.:.::*:**:*: :** :    . .: : **:*.:::.:      

Mb3075c|M.bovis_AF2122/97           VSLRRALRTVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNI
Rv3049c|M.tuberculosis_H37Rv        VSLRRALRTVPGLRALLRLGIYWAQEALAYGMTKRPNTLKIIEAYAKYNI
MMAR_1644|M.marinum_M               PALRRAMENVPGLRALARLGIYWAQEALAFGMTKRPNVLKVGEAYAKYNI
MUL_1880|M.ulcerans_Agy99           PALRRAMENVPGLRALARLGIYWAQEALAFGMTKRPNVLKVGEAYAKYNI
MAV_3915|M.avium_104                PAVRAAMENVPGLRALVRLAIYWGQEALAFGMTKRPNLLKVIEAYAKYNI
TH_4080|M.thermoresistible__bu      AWLRRALENIPGLRLALRGGIYALQEALAVGMTKYPGMLRIGHLLGKWNI
Mflv_4287|M.gilvum_PYR-GCK          EGMQRAFATVPGTRAAMRAGIYWIHETVGFAMTKQPKLLKIGELLGKWNI
Mvan_2059|M.vanbaalenii_PYR-1       EGLQRVFTNVPGTRAAMRAGIYWLHEAVGFAMTKQPRLLKLGELAGKWNI
MSMEG_2310|M.smegmatis_MC2_155      QWLRNVFSYVPGTRALLRAAIYWIHEGVGFAMTKEPRLLKIGEWMGRYNI
MAB_3920c|M.abscessus_ATCC_199      ALAKRAFAGVPGLRALFRSGMYFGAEAGAYAMNRRPALLKGIELLGRAYI
MLBr_00065|M.leprae_Br4923          AARLNRWLPDKYAYTAVRWKNILRQSALYGACQKWP--QRMRNILLGHVA
                                                     *       .    .  : *   :  .       

Mb3075c|M.bovis_AF2122/97           RRSVKDRELRRKLTPRYRIGCKR--ILNSSTYYPAVADPKTELITDRIDR
Rv3049c|M.tuberculosis_H37Rv        RRSVKDRELRRKLTPRYRIGCKR--ILNSSTYYPAVADPKTELITDRIDR
MMAR_1644|M.marinum_M               RRSVKDRELRRKLTPHYRIGCKR--ILNSSSYYPAVANPKTRLITDRIAR
MUL_1880|M.ulcerans_Agy99           RRSVKDRELRRKLTPHYRIGCKR--ILNSSSYYPAVANPKTRLITDRIAR
MAV_3915|M.avium_104                RRSVKDKELRRKLTPHYRIGCKR--ILNSSTYYGAVADPKTELVTDHIAR
TH_4080|M.thermoresistible__bu      NRSVKDPQLRAKLTPDYRLGCKR--ILNSSTYYPAVADPRTEVITESIDR
Mflv_4287|M.gilvum_PYR-GCK          RRSVKDPVLRRKLTPDYRAGCKR--ILNSDTYYRGIADPRTEVITDRIAR
Mvan_2059|M.vanbaalenii_PYR-1       RRSIKDRELRRKLTPDYRAGCKR--ILNSDTYYRGIADPRTEVITDRIAR
MSMEG_2310|M.smegmatis_MC2_155      NRSIKDPELRRKLTPSYRAGCKR--ILNSDTYYRGIADPKTQVITEGIAR
MAB_3920c|M.abscessus_ATCC_199      KSQISDPEVRRKVTPDYRAGCKR--LLGSATYYKAIENRKTELVTEAITR
MLBr_00065|M.leprae_Br4923          RRLPKGYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDR
                                    .   ..  :: :. * *.   :*  :: .   : .: .  . ::*: * *

Mb3075c|M.bovis_AF2122/97           ITHDGIVTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVD
Rv3049c|M.tuberculosis_H37Rv        ITHDGIVTADGTGREVFREADVIVYATGFHVTDSYTYVQIKGRHGEDLVD
MMAR_1644|M.marinum_M               ITRNGIVTADG----VEHQADVIVYATGFHVTDSYTYVQIKGQHGEDLVD
MUL_1880|M.ulcerans_Agy99           ITRNGIVTADG----VEHQADVIVYATGFHVTDSYTYVQIKGQHGEDLVD
MAV_3915|M.avium_104                ITPDGIVTADG----THRPVDVIVYATGFHVTDSYTYVQIKGLHGEDLVD
TH_4080|M.thermoresistible__bu      ITTDGIVTSDG----TERAVDVIVYATGFHVSDSYKYVQIKGLNGEDIVD
Mflv_4287|M.gilvum_PYR-GCK          FTARGIVTADEHGRETEREADVVVFATGFHVTDSYTYVDIKGPGGEDLVD
Mvan_2059|M.vanbaalenii_PYR-1       FSPRGIVTTDEHGRETEREADVVVFATGFHVTDSYTYVDIKGPGGVDLVD
MSMEG_2310|M.smegmatis_MC2_155      MTPTGIVTNDG----VEHPVDIVVYATGFHVTDSYTYVDIKGAGGEDLVD
MAB_3920c|M.abscessus_ATCC_199      VTTDGVVTSDG----IERKVDAIIFGTGFHVTDSYKYLDLKGQGGEDLGE
MLBr_00065|M.leprae_Br4923          FTSTGIRLKSG----NELRADIIVTATGLNLQLFGGAVATVDGQPVDLAQ
                                    .:  *:   .         .* :: .**:::      :   .    *: :

Mb3075c|M.bovis_AF2122/97           RWNREGIGAHRGITVANMPNLFFLLGPNTGLGHNSVVFMIESQIHYVADA
Rv3049c|M.tuberculosis_H37Rv        RWNREGIGAHRGITVANMPNLFFLLGPNTGLGHNSVVFMIESQIHYVADA
MMAR_1644|M.marinum_M               RWNREGIGAHRGIAVADVPNLFFLLGPNTGLGHNSVVFMIESQIHYVADA
MUL_1880|M.ulcerans_Agy99           RWNREGIGAHRGIAVADVPNLFFLLGPNTGLGHNSVVFMIESQIHYVADA
MAV_3915|M.avium_104                RWNREGIGAHRGITVADVPNLFFLLGPNTGLGHNSVVFMIESQIRYVADA
TH_4080|M.thermoresistible__bu      RFNREGPMAHRGTAVADLPNAYLLLGPNTGLGHNSMVYMIESQINYVIEA
Mflv_4287|M.gilvum_PYR-GCK          RWNREGISALRGITVAGMPNLFFLLGPNTALGHNSVVFMIESQIRYAAKA
Mvan_2059|M.vanbaalenii_PYR-1       RWNREGIAALRGITVADMPNLFFLLGPNTALGHNSVVFMIESQIRYAAKA
MSMEG_2310|M.smegmatis_MC2_155      RWNREGIQAHRGVAVAGMPNLFFLLGPNTALGHNSVVFMIEQQIRYVGQA
MAB_3920c|M.abscessus_ATCC_199      RWSSQGVTAHRGITIAGMPNLFFLLGPNTGLGHNSIVFMIESQIHYVTEA
MLBr_00065|M.leprae_Br4923          TMS------YKGMMLSGLPNMIYTVG----YTNASWTLKADLVSEFFCRL
                                      .       :*  ::.:**    :*      : * .   :   .:    

Mb3075c|M.bovis_AF2122/97           IAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGK
Rv3049c|M.tuberculosis_H37Rv        IAKCDRMGVQALAPTREAQDRFNQELQRRLAGSVWNSGGCRSWYLDEHGK
MMAR_1644|M.marinum_M               IAKCDKRGAQALAPTRAAQDRFNEELQRRLAGSVWNSGGCSSWYLDEHGR
MUL_1880|M.ulcerans_Agy99           IAKCDKRGAQALAPTRAAQDRFNEELQRRLAGSVWNSGGCSSWYLDEHGR
MAV_3915|M.avium_104                IATCDKLGAQALAPTRAAQDRFNDELQRRLGPSVWNSGGCSSWYLDEHGK
TH_4080|M.thermoresistible__bu      IKAVDKAGAQALAPTREAQDRYNAELQARLGRSVWNTGGCRSWYLDEHGN
Mflv_4287|M.gilvum_PYR-GCK          IAAVEKKGVQCLTPTREAQDAYNDELQDDLRGTVWSTGGCRSWYLDEHGV
Mvan_2059|M.vanbaalenii_PYR-1       IAAVDKAGAQALAPTRAAQDDYNDELQHDLGGTVWSTGGCRSWYLDEHGV
MSMEG_2310|M.smegmatis_MC2_155      IAAVDKAGAAALAPTRRAQDAFNAELQRDLSGTVFNTGGCKSWYLDEHGV
MAB_3920c|M.abscessus_ATCC_199      IKQVDAAYAQALVPTREAQDRFNAEVQRKLQGSVWNSGGCQSWYLDEHGK
MLBr_00065|M.leprae_Br4923          LNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDA----LPKQG-
                                    :   :      :.    ..*  :  .       *  : ..    * ::* 

Mb3075c|M.bovis_AF2122/97           NTVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN------
Rv3049c|M.tuberculosis_H37Rv        NTVLWCGYTWQYWLTTRSVNPAEYRFFGIGNGLSSDRATVAAAN------
MMAR_1644|M.marinum_M               NTVLWCGYTWQYWLATRSVKPEEYQFFKAG-----AKSSVNG--------
MUL_1880|M.ulcerans_Agy99           NTVLWCGYTWQYWLATRSVKPEEYQFFKAG-----AKSSVNG--------
MAV_3915|M.avium_104                NTVLWGGYTWEYWRATRAVKPEEYQFYGIG-----SRAGV----------
TH_4080|M.thermoresistible__bu      NRVLWGGFTWQYRLATRTLDPAEYRFWG----------------------
Mflv_4287|M.gilvum_PYR-GCK          NRTLWSGMTWQYWLATRRFKESEYTFG-----------------------
Mvan_2059|M.vanbaalenii_PYR-1       NRTLWSGMTWQYWLATRRFNKSEYTFR-----------------------
MSMEG_2310|M.smegmatis_MC2_155      NRTLWSGMTWQYWKALRRLDPSEFEFLDQRVLARS---------------
MAB_3920c|M.abscessus_ATCC_199      NRTLWSGFTFEYWSQTRKVDPSEYEFEGAVRPAVRRTIPRADGPRQKSPS
MLBr_00065|M.leprae_Br4923          SRTPWR-LNQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV----------
                                    . . *   . :*    * .   :                           

Mb3075c|M.bovis_AF2122/97           ----
Rv3049c|M.tuberculosis_H37Rv        ----
MMAR_1644|M.marinum_M               ----
MUL_1880|M.ulcerans_Agy99           ----
MAV_3915|M.avium_104                ----
TH_4080|M.thermoresistible__bu      ----
Mflv_4287|M.gilvum_PYR-GCK          ----
Mvan_2059|M.vanbaalenii_PYR-1       ----
MSMEG_2310|M.smegmatis_MC2_155      ----
MAB_3920c|M.abscessus_ATCC_199      MAAQ
MLBr_00065|M.leprae_Br4923          ----