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MREDDLILVSIDDHVVEPPDMFLRHVPEKYKEEAPIVVTDEKGVDQWMYQGRPQGVSGLNAVVSWPAEEW GRDPAGFAEMRPGVYDVHERVRDMNRNGILASMCFPTFTGFSARHLNMTREDVTLVMVSAYNDWHIDEWA GSYPDRFIPIAILPTWTPEGMCNEIRRVAAKGCRAVTMPELPHLEGLPSYHDEDYWGPVFRTLSEENVVM CLHIGTGFGAISMAPNAPIDNLIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDR HYTNQKWLRRDFGDKLPSDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVLAE LNAAGASDSDINKITWQNSCRFFGWDPFKLTPRDQATAGALRAKAADVDTSIRPRAEWARLYHEKQLTKA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2371 | - | - | 100% (420) | amidohydrolase 2 |
| M. gilvum PYR-GCK | Mflv_4324 | - | e-115 | 47.77% (404) | amidohydrolase 2 |
| M. gilvum PYR-GCK | Mflv_2441 | - | e-115 | 47.52% (404) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0273 | - | 1e-120 | 48.77% (408) | amidohydrolase |
| M. avium 104 | MAV_0860 | - | 0.0 | 92.81% (417) | amidohydrolase 2 |
| M. smegmatis MC2 155 | MSMEG_6547 | - | 0.0 | 92.62% (420) | amidohydrolase 2 |
| M. thermoresistible (build 8) | TH_2339 | - | 0.0 | 91.11% (416) | amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3143 | - | 8e-68 | 37.90% (372) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_4275 | - | 0.0 | 95.19% (416) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2371|M.gilvum_PYR-GCK -----MREDDLILVSIDDHVVEPPDMFLRHVPEKYKEEAPIVVTDEKGVD
Mvan_4275|M.vanbaalenii_PYR-1 -----MQTDDLILVSIDDHVVEPPDMFLRHVPAKYREEAPIVVTDDKGVD
MAV_0860|M.avium_104 -----MKADDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDDKGVD
MSMEG_6547|M.smegmatis_MC2_155 -----MQTDDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDEKGVD
TH_2339|M.thermoresistible__bu -MSHDLRPEDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDENGVD
MMAR_0273|M.marinum_M -----MNTDDMILISVDDHIVEPPDMFDNHLPAKYLRDAPRLVRNPDGSD
MUL_3143|M.ulcerans_Agy99 MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRAPRVVETDDGGQ
::*:***:***** * ::* :: ** :* .* :
Mflv_2371|M.gilvum_PYR-GCK QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
Mvan_4275|M.vanbaalenii_PYR-1 QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
MAV_0860|M.avium_104 QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
MSMEG_6547|M.smegmatis_MC2_155 QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
TH_2339|M.thermoresistible__bu QWMYQGRPQGVSGLNAVVSWPPEEWGRNPARFAEMRPGVYDVHERVRDMN
MMAR_0273|M.marinum_M VWKFRDSVIPNPALNAVAGRPKEEYGLEPQGLDEIRPGCYQVDERVKDMN
MUL_3143|M.ulcerans_Agy99 VWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGAWDIHERIKDMD
* : . .:***.. * .*:* :* : *:* * :::.**::**:
Mflv_2371|M.gilvum_PYR-GCK RNGILASMCFPTFT-GFSARHLN--MTREDVTLVMVSAYNDWHIDEWAGS
Mvan_4275|M.vanbaalenii_PYR-1 RNGILASMCFPTFT-GFSARHLN--MHREEATLVMVSAYNDWHIDEWAGS
MAV_0860|M.avium_104 RNGILASMCFPTFT-GFSARHLN--MHREEVTLVMVSAYNDWHIDEWAGS
MSMEG_6547|M.smegmatis_MC2_155 RNGILASMCFPTFT-GFSARHLN--MHREEATLVMVSAYNDWHIDEWAGS
TH_2339|M.thermoresistible__bu RNGILASMCFPTFT-GFSARHLN--MHREHVTLIMVSAYNDWHIDEWAGS
MMAR_0273|M.marinum_M AGGILASICFPSFP-GFAGRRFA--TDDPDFSLALIQAYNDWHIDQWCGA
MUL_3143|M.ulcerans_Agy99 LNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGP
.*: **: **:* **:.::: . : : *:****:: *.*.
Mflv_2371|M.gilvum_PYR-GCK YPDRFIPIAILPTWTPEGMCNEIRRVAAKGCRAVTMPELPHLEGLPSYHD
Mvan_4275|M.vanbaalenii_PYR-1 YPDRFIPIAILPTWNVEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MAV_0860|M.avium_104 YPDRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MSMEG_6547|M.smegmatis_MC2_155 YPDRFIPIAILPTWNPEAMCREIRRVAAKGCRAVTMPELPHLEGLPSYHD
TH_2339|M.thermoresistible__bu YPGRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MMAR_0273|M.marinum_M YPARFIPMALPVIWDAQACATEVRRVSKKGVHALTFTENPATMGYPSFHN
MUL_3143|M.ulcerans_Agy99 YPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHS
** *:** : .. . ::. : :* :*:::.* * * ** *.
Mflv_2371|M.gilvum_PYR-GCK EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
Mvan_4275|M.vanbaalenii_PYR-1 DDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
MAV_0860|M.avium_104 EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNMIILATQVSAM
MSMEG_6547|M.smegmatis_MC2_155 DDYWGPVFTTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
TH_2339|M.thermoresistible__bu EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPDAPIDNMIILATQVSAM
MMAR_0273|M.marinum_M -DYWNPLWKALCDTNTVMNIHFGSSGNLVTTAPDAPIDVLMTLGPMNIVQ
MUL_3143|M.ulcerans_Agy99 -GHWDPMMAACAETGTVVNLHIGSSGSSPSTTDDAPADVPGVLFFAYAIS
.:*.*: : .: ..*: :*:*:. . : : :** * *
Mflv_2371|M.gilvum_PYR-GCK CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
Mvan_4275|M.vanbaalenii_PYR-1 CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
MAV_0860|M.avium_104 CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYSNQ--KWLRR
MSMEG_6547|M.smegmatis_MC2_155 CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
TH_2339|M.thermoresistible__bu CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRCDRHYTNQ--KWLRR
MMAR_0273|M.marinum_M AAADLLWSRPIKDYPDLKIGLSEGGTGWIPYFLERADRVFEMHS-TWTHQ
MUL_3143|M.ulcerans_Agy99 AAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLDHMLSYHEMYGTWR
.* * *:. :****: :*** **:. *:* *: : :
Mflv_2371|M.gilvum_PYR-GCK DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
Mvan_4275|M.vanbaalenii_PYR-1 DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MAV_0860|M.avium_104 DFGSQLP-SEVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MSMEG_6547|M.smegmatis_MC2_155 DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
TH_2339|M.thermoresistible__bu DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MMAR_0273|M.marinum_M DFGGKLP-SEVFREHFLACFISDPVGVKLRNMIGIDNIAWEADYPHSDSM
MUL_3143|M.ulcerans_Agy99 AMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIMVESDYPHCDST
:* .*. ::** .: * : * .. : ** : * *.****.*.
Mflv_2371|M.gilvum_PYR-GCK WPDAPEQVLAELNAAGASDSDINKITWQNSCRFFGWDPFKLTPRDQATAG
Mvan_4275|M.vanbaalenii_PYR-1 WPDAPEKVLAELNAAGASDSDINKITWENSCRFFSWDPFKLTPKEQATAG
MAV_0860|M.avium_104 WPDAPEQVLAELTAAGADDADINKITWANACRFFSWDPFARTPRDQATVK
MSMEG_6547|M.smegmatis_MC2_155 WPDAPEQVLAELNAAGASDSDIHKITWENACRFFSWDPFARTAREEATVK
TH_2339|M.thermoresistible__bu WPDAPEQVHAELRAAGADDFDINKITWENSCRFFSWDPFEHTPRAEATVG
MMAR_0273|M.marinum_M WPGAPEELGEVLTANSVPDLEVDKMTHLNAMRWYSFDPFSRIPREQATVG
MUL_3143|M.ulcerans_Agy99 WPHTQQTMHEQLDGLPAD--VIRKITWENAARLYQHPVPVAIAQNPEAF-
** : : : * . . : *:* *: * : .: :
Mflv_2371|M.gilvum_PYR-GCK ALRAKAADVDTSIRPRAEWARLYHEK-QLTKA-
Mvan_4275|M.vanbaalenii_PYR-1 ALRAKATDVDTSIRPRAEWARLYNEKQQFAQA-
MAV_0860|M.avium_104 ALRAKALDVDVSIRSRAEWARRYHEK-QLAGQT
MSMEG_6547|M.smegmatis_MC2_155 ALRAKGSDVDVSIRSRAEWRRLYEEK-QLAKA-
TH_2339|M.thermoresistible__bu ALRAKATDVDTTIRSRAEWAQLYEQKQQFAQA-
MMAR_0273|M.marinum_M ALRKAAAGHDVSTRPRSQHKSGERTS-ILVEP-
MUL_3143|M.ulcerans_Agy99 ---------------------------------