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M. smegmatis MC2 155 MSMEG_6547 (-)

annotation: amidohydrolase 2
coordinates: 6603696 - 6604958
length: 420

MQTDDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDEKGVDQWMYQGRPQGVSGLNAVVSWPAEEW
GRDPAGFAEMRPGVYDVHERVRDMNRNGILASMCFPTFTGFSARHLNMHREEATLVMVSAYNDWHIDEWA
GSYPDRFIPIAILPTWNPEAMCREIRRVAAKGCRAVTMPELPHLEGLPSYHDDDYWGPVFTTLSEENVVM
CLHIGTGFGAISMAPNAPIDNLIILATQVSAMCAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDR
HYTNQKWLRRDFGDKLPSDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCFWPDAPEQVLAE
LNAAGASDSDIHKITWENACRFFSWDPFARTAREEATVKALRAKGSDVDVSIRSRAEWRRLYEEKQLAKA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6547--100% (420)amidohydrolase 2
M. smegmatis MC2 155MSMEG_4837-e-11649.38% (405) amidohydrolase 2
M. smegmatis MC2 155MSMEG_4855-1e-1520.05% (364) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2371-0.092.62% (420) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0273-1e-11949.26% (408) amidohydrolase
M. avium 104MAV_0860-0.094.02% (418) amidohydrolase 2
M. thermoresistible (build 8)TH_2339-0.091.35% (416) amidohydrolase 2
M. ulcerans Agy99MUL_3143-8e-6938.71% (372) amidohydrolase
M. vanbaalenii PYR-1Mvan_4275-0.094.95% (416) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2371|M.gilvum_PYR-GCK          -----MREDDLILVSIDDHVVEPPDMFLRHVPEKYKEEAPIVVTDEKGVD
Mvan_4275|M.vanbaalenii_PYR-1       -----MQTDDLILVSIDDHVVEPPDMFLRHVPAKYREEAPIVVTDDKGVD
MSMEG_6547|M.smegmatis_MC2_155      -----MQTDDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDEKGVD
MAV_0860|M.avium_104                -----MKADDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDDKGVD
TH_2339|M.thermoresistible__bu      -MSHDLRPEDLILVSIDDHVVEPPDMFLRHVPAKYRDEAPIVVTDENGVD
MMAR_0273|M.marinum_M               -----MNTDDMILISVDDHIVEPPDMFDNHLPAKYLRDAPRLVRNPDGSD
MUL_3143|M.ulcerans_Agy99           MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRAPRVVETDDGGQ
                                                ::*:***:***** *  ::* ::   ** :*   .* :

Mflv_2371|M.gilvum_PYR-GCK          QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
Mvan_4275|M.vanbaalenii_PYR-1       QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
MSMEG_6547|M.smegmatis_MC2_155      QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
MAV_0860|M.avium_104                QWMYQGRPQGVSGLNAVVSWPAEEWGRDPAGFAEMRPGVYDVHERVRDMN
TH_2339|M.thermoresistible__bu      QWMYQGRPQGVSGLNAVVSWPPEEWGRNPARFAEMRPGVYDVHERVRDMN
MMAR_0273|M.marinum_M               VWKFRDSVIPNPALNAVAGRPKEEYGLEPQGLDEIRPGCYQVDERVKDMN
MUL_3143|M.ulcerans_Agy99           VWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGAWDIHERIKDMD
                                     * : .      .:***.. * .*:* :*  : *:* * :::.**::**:

Mflv_2371|M.gilvum_PYR-GCK          RNGILASMCFPTFT-GFSARHLN--MTREDVTLVMVSAYNDWHIDEWAGS
Mvan_4275|M.vanbaalenii_PYR-1       RNGILASMCFPTFT-GFSARHLN--MHREEATLVMVSAYNDWHIDEWAGS
MSMEG_6547|M.smegmatis_MC2_155      RNGILASMCFPTFT-GFSARHLN--MHREEATLVMVSAYNDWHIDEWAGS
MAV_0860|M.avium_104                RNGILASMCFPTFT-GFSARHLN--MHREEVTLVMVSAYNDWHIDEWAGS
TH_2339|M.thermoresistible__bu      RNGILASMCFPTFT-GFSARHLN--MHREHVTLIMVSAYNDWHIDEWAGS
MMAR_0273|M.marinum_M               AGGILASICFPSFP-GFAGRRFA--TDDPDFSLALIQAYNDWHIDQWCGA
MUL_3143|M.ulcerans_Agy99           LNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAWNDWHLEAWAGP
                                     .*: **: **:*  **:.:::       . :   : *:****:: *.*.

Mflv_2371|M.gilvum_PYR-GCK          YPDRFIPIAILPTWTPEGMCNEIRRVAAKGCRAVTMPELPHLEGLPSYHD
Mvan_4275|M.vanbaalenii_PYR-1       YPDRFIPIAILPTWNVEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MSMEG_6547|M.smegmatis_MC2_155      YPDRFIPIAILPTWNPEAMCREIRRVAAKGCRAVTMPELPHLEGLPSYHD
MAV_0860|M.avium_104                YPDRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
TH_2339|M.thermoresistible__bu      YPGRFIPIAILPTWNPEAMCAEIRRVAAKGCRAVTMPELPHLEGLPSYHD
MMAR_0273|M.marinum_M               YPARFIPMALPVIWDAQACATEVRRVSKKGVHALTFTENPATMGYPSFHN
MUL_3143|M.ulcerans_Agy99           YPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSENPAMLGLPSIHS
                                    ** *:**  :      .. .  ::. : :* :*:::.* *   * ** *.

Mflv_2371|M.gilvum_PYR-GCK          EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
Mvan_4275|M.vanbaalenii_PYR-1       DDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
MSMEG_6547|M.smegmatis_MC2_155      DDYWGPVFTTLSEENVVMCLHIGTGFGAISMAPNAPIDNLIILATQVSAM
MAV_0860|M.avium_104                EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPNAPIDNMIILATQVSAM
TH_2339|M.thermoresistible__bu      EDYWGPVFRTLSEENVVMCLHIGTGFGAISMAPDAPIDNMIILATQVSAM
MMAR_0273|M.marinum_M               -DYWNPLWKALCDTNTVMNIHFGSSGNLVTTAPDAPIDVLMTLGPMNIVQ
MUL_3143|M.ulcerans_Agy99           -GHWDPMMAACAETGTVVNLHIGSSGSSPSTTDDAPADVPGVLFFAYAIS
                                     .:*.*:  : .: ..*: :*:*:. .  : : :** *    *       

Mflv_2371|M.gilvum_PYR-GCK          CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
Mvan_4275|M.vanbaalenii_PYR-1       CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
MSMEG_6547|M.smegmatis_MC2_155      CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYTNQ--KWLRR
MAV_0860|M.avium_104                CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRSDRHYSNQ--KWLRR
TH_2339|M.thermoresistible__bu      CAQDLLWGPAMRNYPDLKFAFSEGGIGWIPFYLDRCDRHYTNQ--KWLRR
MMAR_0273|M.marinum_M               AAADLLWSRPIKDYPDLKIGLSEGGTGWIPYFLERADRVFEMHS-TWTHQ
MUL_3143|M.ulcerans_Agy99           AAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLDHMLSYHEMYGTWR
                                    .* * *:.     :****: :***  **:.  *:* *:    :      :

Mflv_2371|M.gilvum_PYR-GCK          DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
Mvan_4275|M.vanbaalenii_PYR-1       DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MSMEG_6547|M.smegmatis_MC2_155      DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MAV_0860|M.avium_104                DFGSQLP-SEVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
TH_2339|M.thermoresistible__bu      DFGDKLP-SDVFREHSLACYVTDKTSLKLRHEIGIDIIAWECDYPHSDCF
MMAR_0273|M.marinum_M               DFGGKLP-SEVFREHFLACFISDPVGVKLRNMIGIDNIAWEADYPHSDSM
MUL_3143|M.ulcerans_Agy99           AMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIMVESDYPHCDST
                                     :* .*. ::** .:   * : *  ..  :  ** : *  *.****.*. 

Mflv_2371|M.gilvum_PYR-GCK          WPDAPEQVLAELNAAGASDSDINKITWQNSCRFFGWDPFKLTPRDQATAG
Mvan_4275|M.vanbaalenii_PYR-1       WPDAPEKVLAELNAAGASDSDINKITWENSCRFFSWDPFKLTPKEQATAG
MSMEG_6547|M.smegmatis_MC2_155      WPDAPEQVLAELNAAGASDSDIHKITWENACRFFSWDPFARTAREEATVK
MAV_0860|M.avium_104                WPDAPEQVLAELTAAGADDADINKITWANACRFFSWDPFARTPRDQATVK
TH_2339|M.thermoresistible__bu      WPDAPEQVHAELRAAGADDFDINKITWENSCRFFSWDPFEHTPRAEATVG
MMAR_0273|M.marinum_M               WPGAPEELGEVLTANSVPDLEVDKMTHLNAMRWYSFDPFSRIPREQATVG
MUL_3143|M.ulcerans_Agy99           WPHTQQTMHEQLDGLPAD--VIRKITWENAARLYQHPVPVAIAQNPEAF-
                                    ** : : :   * .  .    : *:*  *: * :        .:   :  

Mflv_2371|M.gilvum_PYR-GCK          ALRAKAADVDTSIRPRAEWARLYHEK-QLTKA-
Mvan_4275|M.vanbaalenii_PYR-1       ALRAKATDVDTSIRPRAEWARLYNEKQQFAQA-
MSMEG_6547|M.smegmatis_MC2_155      ALRAKGSDVDVSIRSRAEWRRLYEEK-QLAKA-
MAV_0860|M.avium_104                ALRAKALDVDVSIRSRAEWARRYHEK-QLAGQT
TH_2339|M.thermoresistible__bu      ALRAKATDVDTTIRSRAEWAQLYEQKQQFAQA-
MMAR_0273|M.marinum_M               ALRKAAAGHDVSTRPRSQHKSGERTS-ILVEP-
MUL_3143|M.ulcerans_Agy99           ---------------------------------