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M. thermoresistible (build 8) TH_2017 (-)

annotation: amidohydrolase 2
coordinates: 3942774 - 3943121
length: 116

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2017--100% (116)amidohydrolase 2
M. thermoresistible (build 8)TH_2339-8e-2556.18% (89) amidohydrolase 2
M. thermoresistible (build 8)TH_2277-7e-0535.09% (57) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2441-9e-5276.52% (115) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4742-1e-4976.07% (117) metal-dependent amidohydrolase
M. avium 104MAV_0907-1e-5177.78% (117) amidohydrolase 2
M. smegmatis MC2 155MSMEG_4837-4e-5381.74% (115) amidohydrolase 2
M. ulcerans Agy99MUL_3143-3e-0950.00% (54) amidohydrolase
M. vanbaalenii PYR-1Mvan_4211-9e-5175.65% (115) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


TH_2017|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4837|M.smegmatis_MC2_155      ----------------MNKDDMILISVDDHIIEPPDMFKNHLPAKYRDEA
MMAR_4742|M.marinum_M               ----------------MNKEDMILISVDDHTVEPPNMFKNHLSAKYLDDA
MAV_0907|M.avium_104                ----------------MNKEDMILISVDDHTVEPPDMFKNHLPKKYLDDA
Mflv_2441|M.gilvum_PYR-GCK          ----------------MDKNDMILISVDDHIVEPPDMFKNHLSKKYLDEA
Mvan_4211|M.vanbaalenii_PYR-1       MSRAPARKGGNGRSAVMNRDDMILISVDDHIVEPPDMFKNHLPRKYLDEA
MUL_3143|M.ulcerans_Agy99           -----------MTDPPRARRRYTVISVDDHIVEPPDTFTGRLPQRFADRA
                                                                                      

TH_2017|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4837|M.smegmatis_MC2_155      PRLVHNPDGSDTWQFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRKGC
MMAR_4742|M.marinum_M               PRLVHNPDGSDMWKFRDTVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGC
MAV_0907|M.avium_104                PRLVHNPDGSDMWKFRDTVIPNVALNAVAGRPKEEYGIEPTGLDEIRPGC
Mflv_2441|M.gilvum_PYR-GCK          PRLVHNEDGSDTWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGC
Mvan_4211|M.vanbaalenii_PYR-1       PRLVHNPDGSDTWQFRDVVIPNVALNAVAGRPKEEYGLEPQGLDEIRPGC
MUL_3143|M.ulcerans_Agy99           PRVVETDDGGQVWVYDGQVLPNVGFNAVVGRPVSEYGFEPVRFDEMRRGA
                                                                                      

TH_2017|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4837|M.smegmatis_MC2_155      YDPNERVKDMNAGGVLATMNFPSFP-GFAAR--LFATDDEEFSLALVQAY
MMAR_4742|M.marinum_M               YNVDERIKDMNAGGILASICFPSFP-GFAGR--LFATEDPDFSVALVQAY
MAV_0907|M.avium_104                YNVDERVKDMNAGGILASICFPSFP-GFAGR--LFATEDNDFSIALVQAY
Mflv_2441|M.gilvum_PYR-GCK          WQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LFATEDPEFSLALVQAY
Mvan_4211|M.vanbaalenii_PYR-1       WQVDERVKDMNAGGILGSMCFPSFP-GFAGR--LFATEDAEFSLALVQAY
MUL_3143|M.ulcerans_Agy99           WDIHERIKDMDLNGVYASLNFPSFLPGFAGQRLQQVTKDPELAWAAVRAW
                                                                                      

TH_2017|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4837|M.smegmatis_MC2_155      NDWHIDEWCASNPGRFIPMAIPAIWNPGLAAAEVRRVAEKGVHSLTFTEN
MMAR_4742|M.marinum_M               NDWHIDEWCGAYPARFVPMAIPVIWDAEACAAEVRRVAKKGVHALTFTEN
MAV_0907|M.avium_104                NDWHIDEWCGAYPARFIPMAIPVIWDAEECAKEVRRVSKKGVHALTFTEN
Mflv_2441|M.gilvum_PYR-GCK          NDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHSLTFSEN
Mvan_4211|M.vanbaalenii_PYR-1       NDWHVEEWCGAYPARFIPMTLPVIWDPEACAKEIRRNAARGVHSLTFSEN
MUL_3143|M.ulcerans_Agy99           NDWHLEAWAGPYPERIIPCQLPWLLDPSAGAQLIHENAERGFRAVSFSEN
                                                                                      

TH_2017|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4837|M.smegmatis_MC2_155      PSTLGYPSFHDLEYWRPLWQALVDTETVMNVHIGSSGKLAITAPDAPMDV
MMAR_4742|M.marinum_M               PAAMGYPSFHN-EYWNPLWKALCDTNTVMNIHIGSSGRLAITAPDAPMDV
MAV_0907|M.avium_104                PAAMGYPSFHD-EYWNPLWKALVDTNTVMNVHIGSSGRLAITAPDAPMDV
Mflv_2441|M.gilvum_PYR-GCK          PSAMGYPSFHDFDHWKPMWDALVDTDTVLNVHIGSSGRLAITAPDAPMDV
Mvan_4211|M.vanbaalenii_PYR-1       PSAMGYPSFHDFEHWKPMWDALVDTDTVLNVHIGSSGRLAITAPDAPMDV
MUL_3143|M.ulcerans_Agy99           PAMLGLPSIHS-GHWDPMMAACAETGTVVNLHIGSSGSSPSTTDDAPADV
                                                                                      

TH_2017|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4837|M.smegmatis_MC2_155      MITLQPMNIVQAAADLLWSAPIKEFPTLKIALSEGGTGWIPYFLDRVDRT
MMAR_4742|M.marinum_M               MITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERADRT
MAV_0907|M.avium_104                MITLQPMNIVQAAADLLWSRPIKEFPDLKIALSEGGTGWIPYFLERADRT
Mflv_2441|M.gilvum_PYR-GCK          MITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRT
Mvan_4211|M.vanbaalenii_PYR-1       MITLQPMNIVQAAADLLWSRPIKEYPDLKIALSEGGTGWIPYFLERVDRT
MUL_3143|M.ulcerans_Agy99           PGVLFFAYAISAAVDWLYSGLPSRFPDLKICLSEGRIGWVAGLLDRLDHM
                                                                                      

TH_2017|M.thermoresistible__bu      -------------------------------------VQLRHRIGIDNIC
MSMEG_4837|M.smegmatis_MC2_155      FEMHSTW-THQNFGGKLP-SEVFREHFMTCFISDPVGVKNRHMIGIDNIC
MMAR_4742|M.marinum_M               FEMHSTW-THQNFGGKIP-SEVFREHFLTCFISDKVGVALRNMIGIDNIA
MAV_0907|M.avium_104                FEMHSAW-THQDFKGKLP-SEVFREHFLTCFISDKVGVALRNEIGIDNIC
Mflv_2441|M.gilvum_PYR-GCK          YEMHSTW-TGQDFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDNIC
Mvan_4211|M.vanbaalenii_PYR-1       YEMHSTW-TGQDFKGKLP-SEVFREHFLTCFIADPVGVATRHQIGVDNIC
MUL_3143|M.ulcerans_Agy99           LSYHEMYGTWRAMGESLTSAEVFTRNFWFCAVEDKSSFVQHYRIGTENIM
                                                                         .  :  ** :** 

TH_2017|M.thermoresistible__bu      WEADYPHSDSMWPGAPEELWEVLTANNVPDDEINKITHENAMRWYSFDPF
MSMEG_4837|M.smegmatis_MC2_155      WEMDYPHSDSMWPGAPEELSAVFDTYDVPDDEINKITHENAMRLYHFDPF
MMAR_4742|M.marinum_M               WEADYPHSDSMWPGAPEELWDVLSVNDVPDGEINKMTYENAMRWYSFDPF
MAV_0907|M.avium_104                WEADYPHSDSMWPGAPEELWDVLSINNVPDDEINKMTYQNAMRWYSFDPF
Mflv_2441|M.gilvum_PYR-GCK          WEADYPHSDSMWPGAPEQLDEVLKANNVPDDEINKMTYENAMRWYHWDPF
Mvan_4211|M.vanbaalenii_PYR-1       WEADYPHSDSMWPGAPEQLDEVLKVNSVPDDEIDKMTYQNAMRWYHWDPF
MUL_3143|M.ulcerans_Agy99           VESDYPHCDSTWPHTQQTMHEQLDG--LPADVIRKITWENAARLYQHPVP
                                     * ****.** ** : : :   :    :* . * *:* :** * *     

TH_2017|M.thermoresistible__bu      THIPRDKATVGALRKAAEGHDVSIRALSK-KD-KTGASFADFQANAKAVT
MSMEG_4837|M.smegmatis_MC2_155      AHVPKEQATVGALRKAAEGHDVSIRALSK-KD-KTGASFADFQANAKAVS
MMAR_4742|M.marinum_M               SHITREQATVGALRKAAEGHDVSVRALSHHKDARSGSSVAEFTANAKALT
MAV_0907|M.avium_104                THISREQATVGALRKAAEGHDVSIKAQGHDKDSRGGSSFAEFAANAKALT
Mflv_2441|M.gilvum_PYR-GCK          THIAKEQATVGALRKAAEGHDVSIQALSN-KE-KTGTTFSDFAASAKSIS
Mvan_4211|M.vanbaalenii_PYR-1       THIPKEQATVGALRKAAEGHDVSIQALSH-KE-KTGATFADFAARAKEIT
MUL_3143|M.ulcerans_Agy99           VAIAQNPEAF----------------------------------------
                                      :.::  :.                                        

TH_2017|M.thermoresistible__bu      GVKD
MSMEG_4837|M.smegmatis_MC2_155      GARD
MMAR_4742|M.marinum_M               GNKD
MAV_0907|M.avium_104                GNKD
Mflv_2441|M.gilvum_PYR-GCK          GNKD
Mvan_4211|M.vanbaalenii_PYR-1       GNTD
MUL_3143|M.ulcerans_Agy99           ----