For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2176 | - | - | 100% (408) | magnesium or manganese-dependent protein phosphatase |
| M. thermoresistible (build 8) | TH_2781 | - | 4e-13 | 25.30% (411) | PUTATIVE stage II sporulation protein E (SpoIIE) |
| M. thermoresistible (build 8) | TH_3243 | - | 9e-13 | 31.42% (226) | PUTATIVE putative putative GAF sensor protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1399c | - | 3e-14 | 30.13% (229) | hypothetical protein Mb1399c |
| M. gilvum PYR-GCK | Mflv_3268 | - | 1e-157 | 73.61% (379) | response regulator receiver protein |
| M. tuberculosis H37Rv | Rv1364c | - | 1e-14 | 30.57% (229) | hypothetical protein Rv1364c |
| M. leprae Br4923 | MLBr_01286 | - | 3e-09 | 31.29% (163) | putative two-component response regulatory protein |
| M. abscessus ATCC 19977 | MAB_1076 | - | 1e-08 | 31.58% (114) | two component response transcriptional regulatory protein MprA |
| M. marinum M | MMAR_1263 | - | 1e-150 | 65.85% (410) | hypothetical protein MMAR_1263 |
| M. avium 104 | MAV_4242 | - | 1e-147 | 65.82% (395) | response regulator receiver modulated serine phosphatase |
| M. smegmatis MC2 155 | MSMEG_6131 | - | 1e-160 | 70.83% (408) | magnesium or manganese-dependent protein phosphatase |
| M. ulcerans Agy99 | MUL_2625 | - | 1e-149 | 65.85% (410) | hypothetical protein MUL_2625 |
| M. vanbaalenii PYR-1 | Mvan_2987 | - | 1e-161 | 74.67% (379) | response regulator receiver protein |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2176|M.thermoresistible__bu MPMRAPHESEPLPMAGLGAVPTGQTQPISLLLVEDDRADALLVEELIADT
MSMEG_6131|M.smegmatis_MC2_155 --MRAPFDR--VIASPVDLTGPGQRR-LSLLLVEDDRADAILVEELIADA
Mflv_3268|M.gilvum_PYR-GCK --MLAPTDG----------------EMLSLLLVEDDRADAILVEELIADA
Mvan_2987|M.vanbaalenii_PYR-1 --MLAPNDG----------------DSLSLLLVEDDRGDAILVEELIADA
MMAR_1263|M.marinum_M --MRVPHEHDLTAGLGPSTGQRAQWQTLSLLLVEDDRADAMLVEELIADA
MUL_2625|M.ulcerans_Agy99 --MRVPHEHDLTAGLGPSTGQRAQWQTLSLLLVEDARADAMLVEELIADA
MAV_4242|M.avium_104 ---MIPAQAAVTP-----AAQRQSLKPLSVLLVEDDRGDAVLVEELVTDA
Mb1399c|M.bovis_AF2122/97 ----MAAEMDWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYR
Rv1364c|M.tuberculosis_H37Rv ----MAAEMDWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYR
MLBr_01286|M.leprae_Br4923 --MTGPTTD------------ADAATPHRVLIAEDEALIRLDLAEMLRDE
MAB_1076|M.abscessus_ATCC_1997 -------------------------MPVRILVVDDDRAVRESLRRSLSFN
::. :
TH_2176|M.thermoresistible__bu NADIRVTWAASVADAQHRLAADRPDCVLLDLNLPDADGIDALDRICGYDA
MSMEG_6131|M.smegmatis_MC2_155 -PDIDFVWAKSMSDAERTLADHRPDCVLLDLNLPDAAGIDALHHLGKLDA
Mflv_3268|M.gilvum_PYR-GCK GVDIDVVWAESMAKAEQEIAIARPDCVLLDLHLHDTTGIDGLNRISKQDA
Mvan_2987|M.vanbaalenii_PYR-1 GGDIQVVWAESMARAEQEIAIARPDCILLDLHLHDTDGIDGVNRIAKYDA
MMAR_1263|M.marinum_M AVDIQVVWARSMAHAERELSAARPDCVLLDLNLPDASGIDALDRIANRDA
MUL_2625|M.ulcerans_Agy99 AVDIQVVWARSMAHAERELSAARPDCVLLDLNLPDASGIDALDRIANRDA
MAV_4242|M.avium_104 VTDIRVVWAQSMAHAERELESTRPDCVLLDLHLPDASGIDALNRIAKLDA
Mb1399c|M.bovis_AF2122/97 GFSPLLDTVGQPAREVYPELEGQQIYEMLDRVYQTGEPQSGSEWRLQTDY
Rv1364c|M.tuberculosis_H37Rv GFSPLLDTVGQPAREVYPELEGQQIYEMLDRVYQTGEPQSGSEWRLQTDY
MLBr_01286|M.leprae_Br4923 GYDIVGEAADGQEAVELAER-HKPDLVIMDVKMPRRDGIDAASEIAS-KR
MAB_1076|M.abscessus_ATCC_1997 GYSVDLAEDG--VDALNVIANDRPDALVLDVMMPKLDGLEVCRRLRSTGD
. : ::* .
TH_2176|M.thermoresistible__bu TMPIVVLTGLIDEHFGVLAVASGAQDYLIKGRVEPESLRRSVLYAIERKR
MSMEG_6131|M.smegmatis_MC2_155 RIPIIVLTGLNDEHFGVSAVASGAQDYLVKGRVEPEMLRRAVLYAIERKR
Mflv_3268|M.gilvum_PYR-GCK TIPVVVLTGLNDEHFGVSAVSAGAQDYLIKGRVDSEVLRRAVLYAIERKR
Mvan_2987|M.vanbaalenii_PYR-1 TLPIVVLTGLNDEHVGVSAVSAGAQDYLIKDRVDPEVLRRAVLYAIERKR
MMAR_1263|M.marinum_M TVPVVVLTGLNDEYFGATAVAAGAQDYLVKGRVDPEMLRRAMLYAIERKR
MUL_2625|M.ulcerans_Agy99 TVPVVVLTGLNDEYFGATAVAAGAQDYLVKGRVDPEMLRRAMLYAIERKR
MAV_4242|M.avium_104 TVPIVVLTGLNDEYFGASAVAAGAQDYLVKGRVEPEMLRRALLYAIERKR
Mb1399c|M.bovis_AF2122/97 DG-----SGVEERYFDFVVTPRRRADGSIEG--VQLIVDDVTSRVRARQA
Rv1364c|M.tuberculosis_H37Rv DG-----SGVEERYFDFVVTPRRRADGSIEG--VQLIVDDVTSRVRARQA
MLBr_01286|M.leprae_Br4923 IAPIVVLTAFSQRDLVERARDAGAMAYLVKPFTISDLIPAIALAMSRFSE
MAB_1076|M.abscessus_ATCC_1997 DLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLAR--MRALLRRT
:. . : :
TH_2176|M.thermoresistible__bu HELTAVDLQASRLQAQENARLERGLLPSPLLLDEPGFDIVAQYRPSHQHA
MSMEG_6131|M.smegmatis_MC2_155 AELTSVDLHASQLRAQENARLERGLLPSPLLMEGSGVDIVVEARPSRQHA
Mflv_3268|M.gilvum_PYR-GCK AELTTVDLHASQLRARENARLERGLLPSPLLLDDPGVEIVTQYRPSRENA
Mvan_2987|M.vanbaalenii_PYR-1 AELTAVDLHASQLRARENARLERGLLPSPLLLDDPGVEIVAQYQPSRENA
MMAR_1263|M.marinum_M AELIAADLHATQLRARENALLERGLLPSPLLLDSPGVDIVARYRPSREDA
MUL_2625|M.ulcerans_Agy99 AELIAADLHATQLRARENALLERGLLPSPLLLDSPGVDIVARYRPSREDA
MAV_4242|M.avium_104 AELIAADLHATQLRARENALLERGLLPSPLLLDDPGVDIVARYRPSREDA
Mb1399c|M.bovis_AF2122/97 AEARVEELSERYRNVRDSATVMQQALLAASVPVVPGADIAAEYLVAAEDT
Rv1364c|M.tuberculosis_H37Rv AEARVEELSERYRNVRDSATVMQQALLAASVPVVPGADIAAEYLVAAEDT
MLBr_01286|M.leprae_Br4923 LTALEREVATLADRLETRKLVER---------------------------
MAB_1076|M.abscessus_ATCC_1997 TIDESADAATLSFGDLTLDPVTR---------------------------
: : :
TH_2176|M.thermoresistible__bu LLGGDFYDFVQTPDQTLHVMVGDVSGHGPDEAAVGVALRIGWRALTFAGL
MSMEG_6131|M.smegmatis_MC2_155 LIGGDFYDVVQTPDRTVHVMIGDVAGHGPDEAALGVALRIGWRALTFAGL
Mflv_3268|M.gilvum_PYR-GCK LLGGDFYDFVQTPDRTVHVMIGDVAGHGADEAALGVALRIAWRALTFAGL
Mvan_2987|M.vanbaalenii_PYR-1 LLGGDFYDFVQTPDRTVHVMIGDVAGHGPDEAALGVALRIAWRALTFAGL
MMAR_1263|M.marinum_M LLCGDFYDVVQTADRVVHVLIGDVAGHGPNEAALGAALRIAFRALTLAGV
MUL_2625|M.ulcerans_Agy99 LLCGDFYDVVQTVDRVVHVLIGDVAGHGPNEAALGAALRIAFRALTLAGV
MAV_4242|M.avium_104 LLCGDFYDVVQTPDRVVHVLIGDVAGHGPHEAALGAALRIAFRALTLAGV
Mb1399c|M.bovis_AF2122/97 AAGGDWFDALALGDR-LVLVVGDVVGHGVEAAAVMSQLRTALRMQISTGY
Rv1364c|M.tuberculosis_H37Rv AAGGDWFDALALGDR-LVLVVGDVVGHGVEAAAVMSQLRTALRMQISAGY
MLBr_01286|M.leprae_Br4923 -------------------------AKGLLQVKQGMTEPEAFKWIQRAAM
MAB_1076|M.abscessus_ATCC_1997 -----------------------EVHRGTRSISLTRTEFALLEMLMANPR
:* .
TH_2176|M.thermoresistible__bu RGNERMWQLERILRAERPGRGIFATVLSIALSPKDL------TFTAVRAG
MSMEG_6131|M.smegmatis_MC2_155 RGNERMRQLDRILTTERPGKGIFATLCSVALEPDSG------RFTVVRAG
Mflv_3268|M.gilvum_PYR-GCK HGSDRMRQLERILRAERAGRGIFATVLSLRIPPTGS------TVTAVRAG
Mvan_2987|M.vanbaalenii_PYR-1 RGSDRMRQLERILRAERGGRGIFATVLSLAIPPEGP------MITAVRAG
MMAR_1263|M.marinum_M HGGQLMRQLDRVLRAERTGEGIFATVLSLAIPPQPAGSADGAHIQVIRAG
MUL_2625|M.ulcerans_Agy99 HGGELMRQLDRVLRAERTGEGIFATVLSLAIPPQPAGSADGAHIQVIRAG
MAV_4242|M.avium_104 HGVELMRQLERVLHSERTGTGIFATVLSLEISPQRP------EVSVIRAG
Mb1399c|M.bovis_AF2122/97 TVVEALEAVDRFHKQVPGSK--SATMCVGSLDFTSG------EFQYCTAG
Rv1364c|M.tuberculosis_H37Rv TVVEALEAVDRFHKQVPGSK--SATMCVGSLDFTSG------EFQYCTAG
MLBr_01286|M.leprae_Br4923 DRRTTMKRVAEVVLET------------LDTPKDT---------------
MAB_1076|M.abscessus_ATCC_1997 RVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTE-------------A
: ..
TH_2176|M.thermoresistible__bu HPG-LLVHGPDTVDWLEPPAGPALGLKGTDWPTNEYELPAGHGLLLLTDG
MSMEG_6131|M.smegmatis_MC2_155 HPG-LLVHGNGTVDWLEPRPGAALGLGAREWPVNHYELPEGHGLLLLTDG
Mflv_3268|M.gilvum_PYR-GCK HPG-MLLHGRGTVEWVEPPGGPALGLHGSDWAPQHLELPEGMGLVLLTDG
Mvan_2987|M.vanbaalenii_PYR-1 HPG-MLLHGGGTVDWVEPAGGPALGLHGSDWTPQQVELPEGKGLVLLTDG
MMAR_1263|M.marinum_M HPG-MLLHGGGTVHWLEPPAGPALGLNLGNWCQHEVELPVDHGLLLLTDG
MUL_2625|M.ulcerans_Agy99 HPG-MLLHGGGTVHWLEPPAGPALGLNLGNWCQHEVELPVDHGLLLLTDG
MAV_4242|M.avium_104 HPG-MLLQGGGTVEWVEPPGGPALGLRADDWPRHQLRLPAGHGLLLLTDG
Mb1399c|M.bovis_AF2122/97 HPPPLLVTADASARYVEPTGAGPLGS-GTGFPVRSEVLNIGDAILFYTDG
Rv1364c|M.tuberculosis_H37Rv HPPPLLVTADASARYVEPTGAGPLGS-GTGFPVRSEVLNIGDAILFYTDG
MLBr_01286|M.leprae_Br4923 --------------------------------------------------
MAB_1076|M.abscessus_ATCC_1997 EGELRLIHTVRGVGYVLRETPP----------------------------
TH_2176|M.thermoresistible__bu LFEGHSGRGYERLGEEGLLDLARSHAALPG-------AEFVHALIDDAEH
MSMEG_6131|M.smegmatis_MC2_155 LFEGHAGRGDERLGESGLLAVARALAATPG-------RDFVTSLINEAES
Mflv_3268|M.gilvum_PYR-GCK LFEGHIGRGNERLGEEGLLEMARSLAHLPG-------REFVDALINGVEA
Mvan_2987|M.vanbaalenii_PYR-1 LFEGHIGSGNERLGEEGLLELARSLAALPG-------RAFVHALINAVEE
MMAR_1263|M.marinum_M LFEGYSGHRRERLGEHGLLSLARSHAGLSG-------PAFVDALIDGAQQ
MUL_2625|M.ulcerans_Agy99 LFEGYSGHRRERLGEHGLLSLARSHAGLSG-------PAFVDALIDGAQQ
MAV_4242|M.avium_104 LYEGYSGRGTQRLGEDGLLALARSQVDRPG-------PAFVDALIDGAQR
Mb1399c|M.bovis_AF2122/97 LIE-RPGRPLEAS-TAEFADLAASIASGSGGFVLDAPARPIDRLCSDTLE
Rv1364c|M.tuberculosis_H37Rv LIE-RPGRPLEAS-TAEFADLAASIASGSGGFVLDAPARPIDRLCSDTLE
MLBr_01286|M.leprae_Br4923 --------------------------------------------------
MAB_1076|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2176|M.thermoresistible__bu RAQAVGGISDDIAVVRVERTR-----------------------------
MSMEG_6131|M.smegmatis_MC2_155 RAQTHGGLSDDIAVIRVERSRR----------------------------
Mflv_3268|M.gilvum_PYR-GCK RAASHGGISDDIAVVRVERTPRR---------------------------
Mvan_2987|M.vanbaalenii_PYR-1 RAAAHGGISDDIAVVRVERTPRA---------------------------
MMAR_1263|M.marinum_M RAQSLGGLTDDIAVLRVERTPA----------------------------
MUL_2625|M.ulcerans_Agy99 RAQSLGGLTDDIAVLRVERTPA----------------------------
MAV_4242|M.avium_104 LARPRGGLTDDIAVLRVERTIT----------------------------
Mb1399c|M.bovis_AF2122/97 LLLRSTGYNDDVTLLAMQRRAPTPPLHITLDATINAARTVRAQLREWLAE
Rv1364c|M.tuberculosis_H37Rv LLLRSTGYNDDVTLLAMQRRAPTPPLHITLDATINAARTVRAQLREWLAE
MLBr_01286|M.leprae_Br4923 --------------------------------------------------
MAB_1076|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2176|M.thermoresistible__bu --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3268|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2987|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1263|M.marinum_M --------------------------------------------------
MUL_2625|M.ulcerans_Agy99 --------------------------------------------------
MAV_4242|M.avium_104 --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 IGADHSDIADIVHAISEFVENAVEHGYATDVSKGIVVEAALAGDGNVRAS
Rv1364c|M.tuberculosis_H37Rv IGADHSDIADIVHAISEFVENAVEHGYATDVSKGIVVAAALAGDGNVRAS
MLBr_01286|M.leprae_Br4923 --------------------------------------------------
MAB_1076|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2176|M.thermoresistible__bu --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3268|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2987|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1263|M.marinum_M --------------------------------------------------
MUL_2625|M.ulcerans_Agy99 --------------------------------------------------
MAV_4242|M.avium_104 --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 VIDRGQWKDHRDGARGRGRGLAMAEALVSEARIMHGAGGTTATLTHRLSR
Rv1364c|M.tuberculosis_H37Rv VIDRGQWKDHRDGARGRGRGLAMAEALVSEARIMHGAGGTTATLTHRLSR
MLBr_01286|M.leprae_Br4923 --------------------------------------------------
MAB_1076|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2176|M.thermoresistible__bu --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3268|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2987|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1263|M.marinum_M --------------------------------------------------
MUL_2625|M.ulcerans_Agy99 --------------------------------------------------
MAV_4242|M.avium_104 --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 PARFVTDTMVRRAAFQQTIDSEFVSLVESGRIVVRGDVDSTTAATLDRQI
Rv1364c|M.tuberculosis_H37Rv PARFVTDTMVRRAAFQQTIDSEFVSLVESGRIVVRGDVDSTTAATLDRQI
MLBr_01286|M.leprae_Br4923 --------------------------------------------------
MAB_1076|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2176|M.thermoresistible__bu --------------------------------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3268|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2987|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_1263|M.marinum_M --------------------------------------------------
MUL_2625|M.ulcerans_Agy99 --------------------------------------------------
MAV_4242|M.avium_104 --------------------------------------------------
Mb1399c|M.bovis_AF2122/97 AVESRSGIAPVTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPG
Rv1364c|M.tuberculosis_H37Rv AVESRSGIAPVTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPG
MLBr_01286|M.leprae_Br4923 --------------------------------------------------
MAB_1076|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2176|M.thermoresistible__bu --------------------------
MSMEG_6131|M.smegmatis_MC2_155 --------------------------
Mflv_3268|M.gilvum_PYR-GCK --------------------------
Mvan_2987|M.vanbaalenii_PYR-1 --------------------------
MMAR_1263|M.marinum_M --------------------------
MUL_2625|M.ulcerans_Agy99 --------------------------
MAV_4242|M.avium_104 --------------------------
Mb1399c|M.bovis_AF2122/97 SPAHHVLSLVQLPVVGADTEDIFAQE
Rv1364c|M.tuberculosis_H37Rv SPAHHVLSLVQLPVVGADTEDIFAQE
MLBr_01286|M.leprae_Br4923 --------------------------
MAB_1076|M.abscessus_ATCC_1997 --------------------------