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M. thermoresistible (build 8) TH_1771 (-)

annotation: clavaldehyde dehydrogenase
coordinates: 3464702 - 3465508
length: 269

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1771--100% (269)clavaldehyde dehydrogenase
M. thermoresistible (build 8)TH_3006-6e-3334.03% (238) PUTATIVE putative clavaldehyde dehydrogenase
M. thermoresistible (build 8)TH_4232-2e-2630.00% (250) PUTATIVE putative NAD dependent epimerase/dehydratase family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0788c-6e-1531.75% (211) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1597-3e-1832.69% (208) short chain dehydrogenase
M. tuberculosis H37RvRv0765c-6e-1531.75% (211) short chain dehydrogenase
M. leprae Br4923MLBr_00862ephD8e-0928.33% (240) short chain dehydrogenase
M. abscessus ATCC 19977MAB_0259c-1e-1633.13% (163) short chain dehydrogenase
M. marinum MMMAR_3514-1e-2932.13% (249) oxidoreductase
M. avium 104MAV_4099-3e-2933.75% (240) NAD dependent epimerase/dehydratase family protein
M. smegmatis MC2 155MSMEG_4742-2e-8561.54% (247) clavaldehyde dehydrogenase
M. ulcerans Agy99MUL_2753-2e-2529.96% (247) oxidoreductase
M. vanbaalenii PYR-1Mvan_5160-1e-1832.69% (208) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1771|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4742|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3514|M.marinum_M               --------------------------------------------------
MUL_2753|M.ulcerans_Agy99           --------------------------------------------------
MAV_4099|M.avium_104                --------------------------------------------------
Mb0788c|M.bovis_AF2122/97           --------------------------------------------------
Rv0765c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_1597|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5160|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00862|M.leprae_Br4923          MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWD
MAB_0259c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_1771|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4742|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3514|M.marinum_M               --------------------------------------------------
MUL_2753|M.ulcerans_Agy99           --------------------------------------------------
MAV_4099|M.avium_104                --------------------------------------------------
Mb0788c|M.bovis_AF2122/97           --------------------------------------------------
Rv0765c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_1597|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5160|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00862|M.leprae_Br4923          GVVPLLAKRFRIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSP
MAB_0259c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_1771|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4742|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3514|M.marinum_M               --------------------------------------------------
MUL_2753|M.ulcerans_Agy99           --------------------------------------------------
MAV_4099|M.avium_104                --------------------------------------------------
Mb0788c|M.bovis_AF2122/97           --------------------------------------------------
Rv0765c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_1597|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5160|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00862|M.leprae_Br4923          DRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSG
MAB_0259c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_1771|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4742|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3514|M.marinum_M               --------------------------------------------------
MUL_2753|M.ulcerans_Agy99           --------------------------------------------------
MAV_4099|M.avium_104                --------------------------------------------------
Mb0788c|M.bovis_AF2122/97           --------------------------------------------------
Rv0765c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_1597|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5160|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00862|M.leprae_Br4923          LRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMV
MAB_0259c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_1771|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4742|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3514|M.marinum_M               --------------------------------------------------
MUL_2753|M.ulcerans_Agy99           --------------------------------------------------
MAV_4099|M.avium_104                --------------------------------------------------
Mb0788c|M.bovis_AF2122/97           --------------------------------------------------
Rv0765c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_1597|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5160|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00862|M.leprae_Br4923          DNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQ
MAB_0259c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_1771|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4742|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_3514|M.marinum_M               --------------------------------------------------
MUL_2753|M.ulcerans_Agy99           --------------------------------------------------
MAV_4099|M.avium_104                --------------------------------------------------
Mb0788c|M.bovis_AF2122/97           --------------------------------------------------
Rv0765c|M.tuberculosis_H37Rv        --------------------------------------------------
Mflv_1597|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5160|M.vanbaalenii_PYR-1       --------------------------------------------------
MLBr_00862|M.leprae_Br4923          LIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD
MAB_0259c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

TH_1771|M.thermoresistible__bu      ------------------MTDRHSNIDGLRLLVVGASSGIGQALAAAAHT
MSMEG_4742|M.smegmatis_MC2_155      ------------------MSSQPPDAAGLRLLVVGASSGIGHAVAESAAK
MMAR_3514|M.marinum_M               ---------------------------MSKTVVIGASSGLGRCIGVGLAR
MUL_2753|M.ulcerans_Agy99           ---------------------------MSKTVVIGASSGLGRCIGVGLAR
MAV_4099|M.avium_104                -------------------------------MVVGASSGLGRCIGVGLAQ
Mb0788c|M.bovis_AF2122/97           ------------------MPRFEPHPARRTTVVAGASSGIGAATATELAG
Rv0765c|M.tuberculosis_H37Rv        ------------------MPRFEPHPARRTTVVAGASSGIGAATATELAG
Mflv_1597|M.gilvum_PYR-GCK          ------------------MPRFDPLPDRRPALVAGASSGIGEATAIRLAA
Mvan_5160|M.vanbaalenii_PYR-1       ------------------MPRFDPLPDRRPALVAGASSGIGEATAIALAA
MLBr_00862|M.leprae_Br4923          LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALAR
MAB_0259c|M.abscessus_ATCC_199      ---------------------MTGLLSGKTVVISGVGTGLGREVALKAHQ
                                                                    : *..:*:*   .     

TH_1771|M.thermoresistible__bu      RGARVALAARRIELLEKLAEQL---DG--SAHELDVADPRAIERVIEATA
MSMEG_4742|M.smegmatis_MC2_155      RGIDVAVAARRIKLLKTLADSI---GG--HAFELDVEDPAAITRVVNEAA
MMAR_3514|M.marinum_M               RGDHVALLARRRERTEAAAKEA---GPGTVAVECDVTDEASCRSALAAAA
MUL_2753|M.ulcerans_Agy99           RGDHVALLARRRER-----------------------DEASCRSTLAAAA
MAV_4099|M.avium_104                RGDRVALLARRRQRIEAAAKDA---GPGAVAIECDVTDQASCASAIGEAV
Mb0788c|M.bovis_AF2122/97           RGFPVALGARRMDKLAELVDKIRADGGEAVAFPLDVTDPESVKSFVAQTV
Rv0765c|M.tuberculosis_H37Rv        RGFPVALGARRMDKLAELVDKIRADGGEAVAFPLDVTDPESVKSFVAQTV
Mflv_1597|M.gilvum_PYR-GCK          NGFPVALGARRVEKLEEIVGKIRADGGEAIAVHLDVTEPDSVKAAVEQTT
Mvan_5160|M.vanbaalenii_PYR-1       HGFPVALGARRVEKCQEIVDKIRADGGEAIAVHLDVTDPDSVKSAVEQTT
MLBr_00862|M.leprae_Br4923          RGAEVVVSDIDEAAAKNTAAQIVASGGVAYAYALDVSDAAAVEAFAEQVS
MAB_0259c|M.abscessus_ATCC_199      DGANVVLGARTRENLERLTTELDDTGGSATWAVTDITDATACQGLIDTAV
                                     *  *.:                              :  :       . 

TH_1771|M.thermoresistible__bu      ERFGRLDAIVFTTA-TVPFALVDHTDVTTWLHAYAVNAVGATHVLRAALP
MSMEG_4742|M.smegmatis_MC2_155      DALGGLDAVVFTST-VIPFAYIEDTDVASWLHAFNVNTLGANNVLRAAVP
MMAR_3514|M.marinum_M               DALGGIDNLVYAPA-ISPLVRLAETDADTWRRVFDTNVIGASLATAAALP
MUL_2753|M.ulcerans_Agy99           DALGGIDNLVYAPA-ISPLVRLAETDADTWRRVFDTNVIGASLATAAALP
MAV_4099|M.avium_104                DALGGIDNIVYTPA-VGPLVRMVDTDADTWRRIFDTNVIGASLVTAAAVP
Mb0788c|M.bovis_AF2122/97           EALGEVELLVSSAG-DMLPGQLHEVSTEAFAEQVQIHLVGANRLATAVLP
Rv0765c|M.tuberculosis_H37Rv        EALGEVELLVSSAG-DMLPGQLHEVSTEAFAEQVQIHLVGANRLATAVLP
Mflv_1597|M.gilvum_PYR-GCK          SQLGDIEVLVAGAG-DTYFGKLDSISTEQFESQIQIHLIGANRVAGAVLP
Mvan_5160|M.vanbaalenii_PYR-1       VELGEIEVLVAGAG-DTYFGKLDAISTEEFESQIQIHLIGANRVATAVLP
MLBr_00862|M.leprae_Br4923          AKHGVPDIVVNNAG-IGQAGRFLDTPPEEFDRVLAVNLGGVVNCCRAFGQ
MAB_0259c|M.abscessus_ATCC_199      KRFGAVDALVNVAAKEDVFGGIEGADLAQWQAMLNTNVVGTLQLVQAAVP
                                       *  : :*  .        .       :      :  *.     *   

TH_1771|M.thermoresistible__bu      HLADD-AVIVVASSHDVG---RPRMGVSAYNASKAALDEMMRSWRTEHPD
MSMEG_4742|M.smegmatis_MC2_155      RLADN-GVVLIASSHDVG---RPRAGVAAYSASKAALDEILHSWRSEHPE
MMAR_3514|M.marinum_M               HLRAA-AGKAVYLSSDAGSHAPPWPGLGAYGVSKAALERLVEAWRAEHPE
MUL_2753|M.ulcerans_Agy99           HLRAA-AGKAVYLSSDAGSHAPPWPGLGAYGVSKAALERLVEAWRAEHPE
MAV_4099|M.avium_104                HLSAS-AGKAVYLSSDAGAFGPPWPGLGAYGVSKAALERLVEAWRAEHPD
Mb0788c|M.bovis_AF2122/97           AMVARRRGDLIFVGSDVG--LRQRPHMGAYGAAKAGLAAMVTNLQMELEG
Rv0765c|M.tuberculosis_H37Rv        AMVARRRGDLIFVGSDVG--LRQRPHMGAYGAAKAGLAAMVTNLQMELEG
Mflv_1597|M.gilvum_PYR-GCK          GMIERRRGDLIFVGSDVA--LRQRPHMGAYGAAKAALVAMVTNYQMELEG
Mvan_5160|M.vanbaalenii_PYR-1       GMIERRRGDLIFVGSDVA--LRQRPHMGAYGAAKAALVAMVTNYQMELEG
MLBr_00862|M.leprae_Br4923          RLVERGTGGHIVNVSSMAA-YAPLQSLSAYCTSKAATYMFSDCLRAELDA
MAB_0259c|M.abscessus_ATCC_199      ELKKK-GGSVVFIGSQSA--FHPQLPQSAYATSKGALQNAMYQLAKELGP
                                     :        :    . .         .** .:*..          *   

TH_1771|M.thermoresistible__bu      LPVIRVSVGPTQD------TEILRGADRDLLGELYRSWAQQGQIPATMSA
MSMEG_4742|M.smegmatis_MC2_155      LSVIRVGVGPTED------TEILRGADRDLLDQLLKLWVEQGALPARMSA
MMAR_3514|M.marinum_M               IGFTCVIVGECAGGEGDAQTGMNIGWDRELAMKAYPLWLARGCMPGKLMP
MUL_2753|M.ulcerans_Agy99           IGFTCVVVGECAGGEGDAQTGTNIGWDRELAMKAYLLWLARGCMPGKLMP
MAV_4099|M.avium_104                IGFTCLIVGECAGGEGDGQTGMNQGWDMDLAMKAVPLWSSRGCMPGKLMP
Mb0788c|M.bovis_AF2122/97           TGVRASIVHPGPT-----LTGMGWQLSAEQVGPMLADWAKWGQARHNYFL
Rv0765c|M.tuberculosis_H37Rv        TGVRASIVHPGPT-----LTGMGWQLSAEQVGPMLADWAKWGQARHNYFL
Mflv_1597|M.gilvum_PYR-GCK          TGVRASIVHPGPT-----KTSMGWSLPAELIGPALEDWAKWGQARHDYFL
Mvan_5160|M.vanbaalenii_PYR-1       TGVRASIVHPGPT-----KTAMGWSLPAELIGPALEDWAKWGQARHDYFL
MLBr_00862|M.leprae_Br4923          VGVGLTTICPGVIDTNIIQSTRIDTPTAKQERVRDRRGQLDMMFRLRRYG
MAB_0259c|M.abscessus_ATCC_199      HKIRLNMVVPTWMYGPPIQLYIGLVAQQRGITQEEVLAELTAKFPLGEMP
                                      .    :                                          

TH_1771|M.thermoresistible__bu      VDDVANTMLSFIAVARANPSVVPEIVHLSPRTPHQSQITSNRGGERNINP
MSMEG_4742|M.smegmatis_MC2_155      LGDVANTLVSLVVTAFENPTVVPEVVQLSPR------IRRRQGRE----P
MMAR_3514|M.marinum_M               VEDLVNIVHTILRTDAA--TSIPVVIARGASAP-AGVLDAGQS-------
MUL_2753|M.ulcerans_Agy99           VEDLVNIVHTILRTDAA--TSIPVVIARGASAP-AGVLDAGQS-------
MAV_4099|M.avium_104                VEDLIDVVHTILRTNAS--TSMPLVVARGAPASQAAFAEANQS-------
Mb0788c|M.bovis_AF2122/97           RPSDLARAIAFVAETPRGCVVVNMEIQPEAPLRDAPAHRQKLVLGEEGMP
Rv0765c|M.tuberculosis_H37Rv        RPSDLARAIAFVAETPRGCVVVNMEIQPEAPLRDAPAHRQKLVLGEEGMP
Mflv_1597|M.gilvum_PYR-GCK          RADDLARAITFVAETPRGGFIANMELQPEAPLSEAKD-RQKLALGEEGMP
Mvan_5160|M.vanbaalenii_PYR-1       RAADLARAITFVAETPRGGFIASMELQPEAPLASVKD-RQQLKVDKEALN
MLBr_00862|M.leprae_Br4923          PDKVADTILSAIKKNKPIRPVAPEAYALYGISRVLPQVLRSTARIRVI--
MAB_0259c|M.abscessus_ATCC_199      ADEDVADAVVFFVSDRARMVTGQTLFVNGGEFFR----------------
                                               .                                      

TH_1771|M.thermoresistible__bu      DT
MSMEG_4742|M.smegmatis_MC2_155      AE
MMAR_3514|M.marinum_M               --
MUL_2753|M.ulcerans_Agy99           --
MAV_4099|M.avium_104                --
Mb0788c|M.bovis_AF2122/97           G-
Rv0765c|M.tuberculosis_H37Rv        G-
Mflv_1597|M.gilvum_PYR-GCK          S-
Mvan_5160|M.vanbaalenii_PYR-1       S-
MLBr_00862|M.leprae_Br4923          --
MAB_0259c|M.abscessus_ATCC_199      --