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M. thermoresistible (build 8) TH_1723 ()

annotation: CONSERVED HYPOTHETICAL PROTEIN
coordinates: 3309987 - 3310949
length: 321

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1723-100% (321)CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)TH_1185-7e-1132.39% (176) PROBABLE CYSTEINE DESULFURASE ISCS (NIFS PROTEIN HOMOLOG)
M. thermoresistible (build 8)TH_3033-1e-0827.59% (261) PUTATIVE cysteine desulfurases, SufS subfamily

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3726c-1e-11265.62% (320) hypothetical protein Mb3726c
M. gilvum PYR-GCKMflv_1319-3e-8955.03% (318) aminotransferase, class V
M. tuberculosis H37RvRv3700c-1e-11265.62% (320) hypothetical protein Rv3700c
M. leprae Br4923MLBr_00842-3e-1126.04% (288) hypothetical protein MLBr_00842
M. abscessus ATCC 19977MAB_0373-2e-8354.43% (316) aminotransferase
M. marinum MMMAR_5211csdB1e-11165.73% (321) selenocysteine lyase, CsdB
M. avium 104MAV_0403-1e-10161.25% (320) pyridoxal-phosphate-dependent transferase
M. smegmatis MC2 155MSMEG_6246-1e-12874.52% (314) pyridoxal-phosphate-dependent transferase
M. ulcerans Agy99MUL_4284csdB1e-11065.42% (321) selenocysteine lyase, CsdB
M. vanbaalenii PYR-1Mvan_5482-1e-8856.47% (317) aminotransferase, class V

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1319|M.gilvum_PYR-GCK          -MDGDAHDLEDTPLAQRWREARPPAAG---VHVDSAACSRQSVAVIEATA
Mvan_5482|M.vanbaalenii_PYR-1       -----------MTLAEQWRAARPPVAG---VHVDSAACSRQSFAVIEAAA
TH_1723|M.thermoresistible__bu      --------------------------------------------------
MSMEG_6246|M.smegmatis_MC2_155      -----------MMLAQQWRDARPKVAG---LHLDSGACSRQSFAVIDATT
Mb3726c|M.bovis_AF2122/97           MRRSGANSPAGDSLADRWRAARPPVAG---LHLDSAACSRQSFAALDAAA
Rv3700c|M.tuberculosis_H37Rv        MRRSGANSPAGDSLADRWRAARPPVAG---LHLDSAACSRQSFAALDAAA
MAV_0403|M.avium_104                -------MSGGTPLADTWRSARPPAAG---LHLDSAACSRQSFAVIEATA
MMAR_5211|M.marinum_M               ---------MTDTLADRWRAARPPAAG---LHLDSAACSRQSLEVLQAVA
MUL_4284|M.ulcerans_Agy99           ---------MTDTLADRWRAARPPATG---LHLDSAACSRQSLEVLRAVA
MAB_0373|M.abscessus_ATCC_1997      -----------MSLRDRWRHARPPVLG---VHLDSAACSRQSIETLRAVA
MLBr_00842|M.leprae_Br4923          ----MVDVFDIQAVRADFPILQETVNGKPLIWFDNAATTQKPQVVIDRLS
                                                                                      

Mflv_1319|M.gilvum_PYR-GCK          QHARHEA----EVGGYVAAEAAAPVLDAGRAAVRVLAGMPDAEVVFTTGS
Mvan_5482|M.vanbaalenii_PYR-1       QHARHEA----EVGGYVAAEAAAPALDAGRTAVRALTGMSDAVVHFTTGS
TH_1723|M.thermoresistible__bu      ------------------------VLHAGRAAVAHLVGMDAADVVFTTGS
MSMEG_6246|M.smegmatis_MC2_155      AHARHEA----EVGGYVAAEAATPALDAGRAAVASLIGFAASDVVYTSGS
Mb3726c|M.bovis_AF2122/97           QHARHEA----EVGGYVAAEAAAAVLDAGRAAVAALSGLPDAEVVFTTGS
Rv3700c|M.tuberculosis_H37Rv        QHARHEA----EVGGYVAAEAAAAVLDAGRAAVAALSGLPDAEVVFTTGS
MAV_0403|M.avium_104                QHARNEA----ELGGYVAAEAAAPVLDAGRFAFTALTGMTDAEAVFTTGS
MMAR_5211|M.marinum_M               AHGLHEA----EVGGYVAAEAAAPVLDAGRAAVATLCGVPDARVVFTTGS
MUL_4284|M.ulcerans_Agy99           AHGLHEA----EVGGYVAAEAAAPVLDAGRAAVATLCGVPDARVVFTTGS
MAB_0373|M.abscessus_ATCC_1997      QHAEHEA----QIGGYVAQEAATPVLEAGRAAVRQLTGMPEAHVQFTTGA
MLBr_00842|M.leprae_Br4923          YFYAHENSNIHRAAHELAARATDAYEEARETARRFIGAAKAQEIIFVRGT
                                                              .* . *   : .       :. *:

Mflv_1319|M.gilvum_PYR-GCK          NNALDILLADWPGE---------RTLACLQGEFGPNLAIMARHGFEVRTL
Mvan_5482|M.vanbaalenii_PYR-1       NHALDILLGDWTGA---------RTLACLPGEFGPNLAIMARHGFSIKVL
TH_1723|M.thermoresistible__bu      NHALDLLLSSWPQP---------RSLACLPGEFGPNLAIMAANGFEVRAL
MSMEG_6246|M.smegmatis_MC2_155      NHAIDLLLSSWPGK---------RTLACLPGEYGPNLSAMAANGFQVRAL
Mb3726c|M.bovis_AF2122/97           LHALDLLLGSWPGEN--------RTLACLPGEYGPNLAVMAAHGFDVRPL
Rv3700c|M.tuberculosis_H37Rv        LHALDLLLGSWPGEN--------RTLACLPGEYGPNLAVMAAHGFDVRPL
MAV_0403|M.avium_104                LHALDLLLGSWPAER--------RTLACLPGEYGPNLAVMAAHGFDRWLL
MMAR_5211|M.marinum_M               LHALDLLLGSWPRES--------RTLACLPGEYGPNLAVMAAHGFEVRLL
MUL_4284|M.ulcerans_Agy99           LHALDLLLGSWPRES--------RTLACLPGEYGPNLAVMAAHGFEVRLL
MAB_0373|M.abscessus_ATCC_1997      ADALRTLLQAWPADSG-------RVVACLPGEFGPNLMIMNHFGFTPVWL
MLBr_00842|M.leprae_Br4923          TEAINLVAYAWGGKHLQPGDEVVITHLEHHANIVPWQLLSSQTGAILKVA
                                     .*:  :   *                   .:  *        *      

Mflv_1319|M.gilvum_PYR-GCK          PLEESGRLDVNAIGAALAHDPPALVHFTVLGSHSGVVQPARAMASACHGH
Mvan_5482|M.vanbaalenii_PYR-1       PVDEFGRLDVNAVGAALSSHQPALVHFTVLGSHSGIVQPVRDMASACRGH
TH_1723|M.thermoresistible__bu      PVDEIGRVRPDRAEHLLRTDPPALVHLTALASHRGIAQPAARIAELCRAY
MSMEG_6246|M.smegmatis_MC2_155      PVDDDGRVLVDEASHELSAHPVALVHLTALASHRGIAQPAAELVEACHNA
Mb3726c|M.bovis_AF2122/97           PTLQDGRVALDDAAFMLADDPPDLVHLTVVASHRGVAQPLAMVAQLCTEL
Rv3700c|M.tuberculosis_H37Rv        PTLQDGRVALDDAAFMLADDPPDLVHLTVVASHRGVAQPLAMVAQLCTEL
MAV_0403|M.avium_104                PTLADGRVALDDAALALQTDPPDLVHLTTIGSHSGVVQPVSMIARLCREL
MMAR_5211|M.marinum_M               PTLDDGRLALDDAAYELEEDPPELVHLTPVASHRGTVQPLAMMAELCREL
MUL_4284|M.ulcerans_Agy99           PTLDDGRLALDDAAYELEEDPPELVHLTPVASHRGTVQPLAMMAELCREL
MAB_0373|M.abscessus_ATCC_1997      PVDGDGRADVDGIEVFLRHEKIDLLHLTVVGSHRGTVQPAAEVVALARAA
MLBr_00842|M.leprae_Br4923          PVDDAGNLLMSEFEDLLG-PRTKLVAATQVSNALGTVTQGEKIVELGHRY
                                    *    *.   .     *      *:  * :..  * .     :.      

Mflv_1319|M.gilvum_PYR-GCK          GIPLIVDAAQGFAHIDVAG--IGADALYSSSRKWTAGPRGVGVLATKPGF
Mvan_5482|M.vanbaalenii_PYR-1       GIPLIVDAAQGFAHLDVAG--IGADALYSSSRKWTAGPRGVGVLASRPGL
TH_1723|M.thermoresistible__bu      RVPLVIDAAQALGHLDCA---VGADAVYSSSRKWLAGPRGVGVLAIRPEL
MSMEG_6246|M.smegmatis_MC2_155      GIPVVIDAAQALGHLDCN---VGADAVYSSSRKWLAGPRGVGVLAVRPEL
Mb3726c|M.bovis_AF2122/97           KLPLVVDAAQGLGHVDCA---VGADVTYASSRKWIAGPRGVGVLAVRPEL
Rv3700c|M.tuberculosis_H37Rv        KLPLVVDAAQGLGHVDCA---VGADVTYASSRKWIAGPRGVGVLAVRPEL
MAV_0403|M.avium_104                GLPLVVDAAQALGQVDCT---AGADVTYSSSRKWIAGPRGVGMLAVRREL
MMAR_5211|M.marinum_M               GLPLVVDAAQGMGQIDCA---VGADVTYSSSRKWLAGPRGVGVLAMRPEV
MUL_4284|M.ulcerans_Agy99           GLPLVVDAAQGMGQIDCA---VGADVTYSSSRKWLAGPRGVGVLAMRPEV
MAB_0373|M.abscessus_ATCC_1997      GVPVVVDAAQALGHIDCT---YGADAMYAPSRKWLAGPRGVGVLAVNP-V
MLBr_00842|M.leprae_Br4923          GARVLIDGAQSIPHLPINVSELGADFFVFSG-HKIYGPTGIGVLYGCEDV
                                       :::*.**.: ::       ***    .. :   ** *:*:*     .

Mflv_1319|M.gilvum_PYR-GCK          LSEATR----------------------QRISHTEANVGMHVGFSVALGE
Mvan_5482|M.vanbaalenii_PYR-1       LADDTR----------------------IRLNHAETNVGLQVGFSVAVGE
TH_1723|M.thermoresistible__bu      AERLCPRLPPPDWPVAR------TLRVLDRLAHGEANIAARVGFSVAVGE
MSMEG_6246|M.smegmatis_MC2_155      AERLQPRIPPSDWPIP--------MSVLEKLELGEHNAAARVGFSVAVGE
Mb3726c|M.bovis_AF2122/97           MERLRARLPAPDWMP--------PLTVAQQLGFGEANVAARVGFSVALGE
Rv3700c|M.tuberculosis_H37Rv        MERLRARLPAPDWMP--------PLTVAQQLGFGEANVAARVGFSVALGE
MAV_0403|M.avium_104                MENLHPRLAAPDWAP--------GSTVAQQLEFGEANIAARVGFSLALGE
MMAR_5211|M.marinum_M               LDRLTPRLAPPDWSPDS-----PSTSVAQILEFGEANIAARVGFSLAVGE
MUL_4284|M.ulcerans_Agy99           LDRLTPRLAPPDWSPDS-----PSTSVAQILEFGEANIAARVGFSLAVGE
MAB_0373|M.abscessus_ATCC_1997      LEHLLP----------------------QWAGHVEAHVAGWVGLSVAVGQ
MLBr_00842|M.leprae_Br4923          LTEMPPWQGGGNMIVDVTLERSLYQGPPNKFEAGTGNIADAVGLGEALRY
                                                                        : .  **:. *:  

Mflv_1319|M.gilvum_PYR-GCK          HVAAGVEAVQARLREVGAATRRALADVRGWRVLEALDEPSAITTLRPPDG
Mvan_5482|M.vanbaalenii_PYR-1       YVAAGPDAVQSRLREVGAATRTALADVPGWRVVEHVTEPSAITTLQSTDG
TH_1723|M.thermoresistible__bu      HLAAGPAAVRARLAEVGRQTHAVLAQVPGWRVVEPPDEPTAITTLEPTAG
MSMEG_6246|M.smegmatis_MC2_155      HLAAGPTAVRERLAEVGRLSRQVLAEVDGWRVVEPVDQPTAITTLESTDG
Mb3726c|M.bovis_AF2122/97           HLACGPQAIRARLAELGDIARTVLADVSGWRVVEAVDEPSAITTLAPIDG
Rv3700c|M.tuberculosis_H37Rv        HLACGPQAIRARLAELGDIARTVLADVSGWRVVEAVDEPSAITTLAPIDG
MAV_0403|M.avium_104                YLGYGPAAVCARLAELGGLSRGVLTDVTGWAVVEEAEEPSAITTLAPTDG
MMAR_5211|M.marinum_M               HLEYGPALIRARLAELGAAARRVLADVDGWLVVEEVDEPSAITTLAPIDG
MUL_4284|M.ulcerans_Agy99           HLEYGPALIRARLAELGAAARRVLADVDGWLVVEEVDEPSAITTLAPIDG
MAB_0373|M.abscessus_ATCC_1997      HLAAGPGQIQGALAERGRAARKILGELKDWRVIESVDEPSAITTLEPVGD
MLBr_00842|M.leprae_Br4923          VERVGVQRIASHEQALLDYATPRLADIPGVRLVGTATEKASVLSFVLAG-
                                        *   :          :   * :: .  ::    : ::: ::     

Mflv_1319|M.gilvum_PYR-GCK          VDAQDVRARLIAEHSIVATYLGTERAPREMN--RPALRVSPHVDVTAADL
Mvan_5482|M.vanbaalenii_PYR-1       IDPLDVRTRLIAEHQIVTTYLGLERAPREMS--HPALRVSPHVDVTDADL
TH_1723|M.thermoresistible__bu      ADPAAVR-RTLIERGIVTTAAEPARAPFELR--TPVLRLSPHIDTTTAEL
MSMEG_6246|M.smegmatis_MC2_155      ADPASVRSWLIAERGIVTTACELARAPFEMR--TPVLRISPHVDVTVDEL
Mb3726c|M.bovis_AF2122/97           ADPAAVRAWLLSQRRIVTTYAGVERAPLELP--APVLRISPHVDNTADDL
Rv3700c|M.tuberculosis_H37Rv        ADPAAVRAWLLSQRRIVTTYAGVERAPLELP--APVLRISPHVDNTADDL
MAV_0403|M.avium_104                ADPRAVRDWLLAERRILTTFVGVQRAPLRLT--APVLRISPHLDTTAEDL
MMAR_5211|M.marinum_M               ADPAAVREWLLEQRRILTTYAGIARAPQELT--APVLRVAPHVDTTAEDL
MUL_4284|M.ulcerans_Agy99           ADPAAEREWLLEQRRILTTYAGIARAPQELT--APVLRVAPHVDTTAEDL
MAB_0373|M.abscessus_ATCC_1997      IDVIAVRARLIEEHAIVTTGAEMVRAPFEMT--KPVLRVSPHVDGTDEEL
MLBr_00842|M.leprae_Br4923          HEPLEVGKALNAEGIAVRAGHHCAQPVLRRLGLEATVRPSFAFYNTYEEI
                                     :          :   : :     :.  .     ..:* :  .  *  ::

Mflv_1319|M.gilvum_PYR-GCK          GRVAEALAEVTPG-----
Mvan_5482|M.vanbaalenii_PYR-1       AALADALATVTR------
TH_1723|M.thermoresistible__bu      EQFAAALADVTAALR---
MSMEG_6246|M.smegmatis_MC2_155      EQFAAALREAP-------
Mb3726c|M.bovis_AF2122/97           DAFAEALVAATAATSGER
Rv3700c|M.tuberculosis_H37Rv        DAFAEALVAATAATSGER
MAV_0403|M.avium_104                ETFAEALIAATAATSA--
MMAR_5211|M.marinum_M               ENFAEALIEATAATTAT-
MUL_4284|M.ulcerans_Agy99           ENFAEALIEATAATTAT-
MAB_0373|M.abscessus_ATCC_1997      ELLAGVLASARRV-----
MLBr_00842|M.leprae_Br4923          DVFINVVRRIAEGGTNIG
                                      .  .: