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M. thermoresistible (build 8) TH_3033 (-)

annotation: cysteine desulfurases, SufS subfamily
coordinates: 3087009 - 3088262
length: 418

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3033--100% (418)cysteine desulfurases, SufS subfamily
M. thermoresistible (build 8)TH_1185-5e-3129.93% (401) PROBABLE CYSTEINE DESULFURASE ISCS (NIFS PROTEIN HOMOLOG)
M. thermoresistible (build 8)TH_1666-2e-2026.40% (394) POSSIBLE AMINOTRANSFERASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1499csd0.086.27% (415) cysteine desulfurase
M. gilvum PYR-GCKMflv_3674-0.083.00% (406) SufS subfamily cysteine desulfurase
M. tuberculosis H37RvRv1464csd0.086.27% (415) cysteine desulfurase
M. leprae Br4923MLBr_00596-0.084.13% (416) putative aminotransferase
M. abscessus ATCC 19977MAB_2746c-0.078.87% (407) cysteine desulfurase/aminotransferase
M. marinum MMMAR_2269csd0.086.51% (415) cysteine desulfurase Csd
M. avium 104MAV_3315-0.085.96% (406) cysteine desulfurase
M. smegmatis MC2 155MSMEG_3125-0.087.35% (411) cysteine desulfurase
M. ulcerans Agy99MUL_1865csd0.086.51% (415) cysteine desulfurase Csd
M. vanbaalenii PYR-1Mvan_2736-0.080.88% (408) SufS subfamily cysteine desulfurase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3674|M.gilvum_PYR-GCK          MTTART-LDLTVLNRVRADFPILSRVMRGGQQLAYLDSGATSQKPLAVLD
MSMEG_3125|M.smegmatis_MC2_155      MTAAKT-LDVTAI---RADFPILSRVMRGGNQLAYLDSGATSQKPLQVLD
MLBr_00596|M.leprae_Br4923          MTISLTPLDLSAI---RADFPILKRVMRGGNQLAYLDSGATSQRPVQVLD
MAV_3315|M.avium_104                ---------MAAI---RADFPILKRIMRSGNQLAYLDSGATSQRPLQVLD
Mb1499|M.bovis_AF2122/97            MTASVNSLDLAAI---RADFPILKRIMRGGNPLAYLDSGATSQRPLQVLD
Rv1464|M.tuberculosis_H37Rv         MTASVNSLDLAAI---RADFPILKRIMRGGNPLAYLDSGATSQRPLQVLD
MMAR_2269|M.marinum_M               MTVSVARLDLAAI---RADFPILQRVMRSGNQLAYLDSGATSQRPLQVLD
MUL_1865|M.ulcerans_Agy99           MTVSVARLDLAAI---RADFPILQRVMRSGNQLAYLDSGATSQRPLQVLD
TH_3033|M.thermoresistible__bu      MTVAPNRLDLGAI---RADFPILQRVMRGGSQLAYLDSGATAQRPVQVLD
Mvan_2736|M.vanbaalenii_PYR-1       MTASVD-LDVAAI---RADFPILKRVMRGGNTLAYLDSGATSQKPLQVLD
MAB_2746c|M.abscessus_ATCC_199      MTATVP-LDITAI---RNDFPILSRTVRGGKPLAYLDSGATSQRPVQVLD
                                             : .:   * *****.* :*.*. *********:*:*: ***

Mflv_3674|M.gilvum_PYR-GCK          AERDFLLHSNGAVHRGAHQLMEESTDAYEHGREAIASFVGADSDELVFTK
MSMEG_3125|M.smegmatis_MC2_155      AEREFLLTSNGAVHRGAHQLMEESTDAYEQGRADIAAFVGADPDELVFTK
MLBr_00596|M.leprae_Br4923          AEREFLVTSNGAVHRGAHQLMEEATDAYERGRVDIAAFIGAAADELVFTK
MAV_3315|M.avium_104                AEREFLLTSNGAVHRGAHQLMEESTDAYEQGRADIAAFVGADPDELVFTK
Mb1499|M.bovis_AF2122/97            AEREFLTASNGAVHRGAHQLMEEATDAYEQGRADIALFVGADTDELVFTK
Rv1464|M.tuberculosis_H37Rv         AEREFLTASNGAVHRGAHQLMEEATDAYEQGRADIALFVGADTDELVFTK
MMAR_2269|M.marinum_M               AEREFLTTCNGAVHRGAHQLMEEATDAYEQGRADIAAFVGAEPDELVFTK
MUL_1865|M.ulcerans_Agy99           AEREFLTTCNGAVHRGAHQLMEEATDAYEQGRADIAAFVGAEPDELVFTK
TH_3033|M.thermoresistible__bu      AEREFLTTSYGAVHRGAHQLMEEATDAYEEGRADIAAFVGADPDELVFTK
Mvan_2736|M.vanbaalenii_PYR-1       AERQFLTTSYGAVHRGAHQLMEESTDAYEQGRADIAAFVGAAPGELVFTK
MAB_2746c|M.abscessus_ATCC_199      AERRFLTERNAAVHRGAHQLAEEATDAYEGARNAIARFVGVDDGEIVFTK
                                    *** **    .********* **:***** .*  ** *:*.  .*:****

Mflv_3674|M.gilvum_PYR-GCK          NATEAINLVAYALGDKRFENAIGPG-DVIVTTELEHHANLVPWQELVLRT
MSMEG_3125|M.smegmatis_MC2_155      NATEAINLVAYVLGDKRFERAVGPG-DVIVTTEVEHHANLVPWQELAERT
MLBr_00596|M.leprae_Br4923          NATESLNLVSYVFGDNRFEGTSGDGGDVIVTTELEHHANLIPWQELARRI
MAV_3315|M.avium_104                NATEALNLVSYVVGDNRFERAVGPG-DVIVTTELEHHANLVPWQELARRT
Mb1499|M.bovis_AF2122/97            NATEALNLVSYVLGDSRFERAVGPG-DVIVTTELEHHANLIPWQELARRT
Rv1464|M.tuberculosis_H37Rv         NATEALNLVSYVLGDSRFERAVGPG-DVIVTTELEHHANLIPWQELARRT
MMAR_2269|M.marinum_M               NATESLNLVSYVLGDSRFDRAIGPG-DVIVTTELEHHANLIPWQELARRT
MUL_1865|M.ulcerans_Agy99           NATESLNLVSYVLGDSRFDRAIGPG-DVIVTTELEHHANLIPWQELARRT
TH_3033|M.thermoresistible__bu      NATEALNLVAYVLGDDRFDRAVGPG-DVIVTTELEHHANLIPWQELARRT
Mvan_2736|M.vanbaalenii_PYR-1       NATEALNLVSYVLGDDRSGFAVGPG-DVIVVTEMEHHANLIPWQELARRT
MAB_2746c|M.abscessus_ATCC_199      NATESLNLVAYTLGDNRFDRAVGPG-DEIVVTELEHHANLVPWQELCRRT
                                    ****::***:*..**.*   : * * * **.**:******:*****  * 

Mflv_3674|M.gilvum_PYR-GCK          GATLKWYGVTAEGRIDLDSLVLDERVKVVAFSHHSNVTGAIAPVSELVAR
MSMEG_3125|M.smegmatis_MC2_155      GATLKWYGVTDSGRIDLDSLELDERVKVVAFSHHSNVTGAVAPVAELVSR
MLBr_00596|M.leprae_Br4923          GATLRWYGVTDDGQIDLDSLQLDERVKVVAFSHHSNVTGAVAPVRELVAR
MAV_3315|M.avium_104                GASLRWYGVTDDGRIDLDSLQLDERVKVVAFSHHSNVTGAVAPVAELVGR
Mb1499|M.bovis_AF2122/97            GATLRWYGVTDDGRIDLDSLYLDDRVKVVAFTHHSNVTGVLTPVSELVSR
Rv1464|M.tuberculosis_H37Rv         GATLRWYGVTDDGRIDLDSLYLDDRVKVVAFTHHSNVTGVLTPVSELVSR
MMAR_2269|M.marinum_M               GATLRWYSVTDEGRIDLDSLQLDERVKVVTFTHHSNVTGALAPVAELVSR
MUL_1865|M.ulcerans_Agy99           GATLRWYSVTDEGRIDLDSLQLDERVKVVTFTHHSNVTGALAPVAELVSR
TH_3033|M.thermoresistible__bu      GAELRWYSVTDDGRIDLDSLELDERVKVVAFTHHSNVTGAIAPVEELVSR
Mvan_2736|M.vanbaalenii_PYR-1       GATLRWFGLTDDGEVDLDSLKLDERVKVVSFSHHSNVTGVGVPVADMVAR
MAB_2746c|M.abscessus_ATCC_199      GATLRWFGVTDDGRIDVDSLELTEAVKVVAFTHQSNVTGAVAPVAELVRR
                                    ** *:*:.:* .*.:*:*** * : ****:*:*:*****. .** ::* *

Mflv_3674|M.gilvum_PYR-GCK          ARAVGALVVLDACQSVPHQPVDFHALDVDFAAFSGHKMLGPTGIGVLYGR
MSMEG_3125|M.smegmatis_MC2_155      AKAVGALTVLDACQSAPHQPVDLHALDVDYAAFSGHKMLGPTGIGVLYGR
MLBr_00596|M.leprae_Br4923          AKEVGALTVLDACQSVPHQPVDLHGLGVDFAAFSGHKMLGPNGIGVLYAR
MAV_3315|M.avium_104                ARAVGALTVLDACQSVPHQPVDFHALDVDFAAFSGHKMLGPNGIGVLYGR
Mb1499|M.bovis_AF2122/97            AHQSGALTVLDACQSVPHQPVDLHELGVDFAAFSGHKMLGPNGIGVLYGR
Rv1464|M.tuberculosis_H37Rv         AHQSGALTVLDACQSVPHQPVDLHELGVDFAAFSGHKMLGPNGIGVLYGR
MMAR_2269|M.marinum_M               AKAVGALTVLDACQSVPHQPVDFHKLDVDFAAFSGHKMLGPNGIGVLYGR
MUL_1865|M.ulcerans_Agy99           AKAVGALTVLDACQSVPHQPVDFHKLDVDFAAFSGHKMLGPNGIGELYGR
TH_3033|M.thermoresistible__bu      ARAVGALTVLDACQSVPHQPVDLHALGVDYAAWSGHKMLGPNGIGALYGR
Mvan_2736|M.vanbaalenii_PYR-1       AKAVGALTVLDSCQAVPHQPVDFHALDVDFAAFSGHKMLGPTGIGALYGR
MAB_2746c|M.abscessus_ATCC_199      AKAVGALVVLDACQSVPHMSVNFRELGVDYAAFSGHKMLGPSGVGVLYGR
                                    *:  ***.***:**:.** .*::: *.**:**:********.*:* **.*

Mflv_3674|M.gilvum_PYR-GCK          RALLNALPPFLTGGSMIETVTMEATTFAPAPQRFEAGTPMTSQVVGLGAA
MSMEG_3125|M.smegmatis_MC2_155      RGLLDAMPPFITGGSMIETVTMEKTTFAPAPQRFEAGTPMTSQVVGLAAA
MLBr_00596|M.leprae_Br4923          RELLSVMPPFLTGGSMIETVTMESTTYAPAPQRFEAGTPMTSQVVGLAAA
MAV_3315|M.avium_104                REVLSQLPPFLTGGSMIETVTMESSSYAPVPQRFEAGTPMASQVVGLAAA
Mb1499|M.bovis_AF2122/97            RELLAQMPPFLTGGSMIETVTMEGATYAPAPQRFEAGTPMTSQVVGLAAA
Rv1464|M.tuberculosis_H37Rv         RELLAQMPPFLTGGSMIETVTMEGATYAPAPQRFEAGTPMTSQVVGLAAA
MMAR_2269|M.marinum_M               RELLAAMPPFLTGGSMIETVTMEASTYAPAPQRFEAGTPMTSQVVGLAAA
MUL_1865|M.ulcerans_Agy99           RELLAAMPPFLTGGSMIETVTMEASTYAPAPQRFEAGTPMTSQVVGLAAA
TH_3033|M.thermoresistible__bu      RELLEAMPPFLTGGSMIETVSMEGATYAPAPQRFEAGTPMTSQVVGLAAA
Mvan_2736|M.vanbaalenii_PYR-1       ARLLEQLPPFLTGGSMIETVTMEGATYAPPPQRFEAGTQMISQVVGLGAA
MAB_2746c|M.abscessus_ATCC_199      RALLEAMPPFITGGSMIETVTMEVSTYAPPPQRFEAGVPMTSQVVGLGAA
                                      :*  :***:*********:** :::** *******. * ******.**

Mflv_3674|M.gilvum_PYR-GCK          ARYLDALGMPAVEEHERELVAAALAGLSEVPGVRVIGPASMDDRGSPVSF
MSMEG_3125|M.smegmatis_MC2_155      ARYLTALGMPAVEAHEAELVAAALEGLAGVPGVRIIGPTAMENRGSPVSF
MLBr_00596|M.leprae_Br4923          ARYLDAIGMKAVEAHERELVAAAVEGLSRIDGVRIIGPKSMENRGSPVSF
MAV_3315|M.avium_104                ARYLGALGMDAVQAHEERLVAAAIEGLSGIDAVRIVGPTSTENRGSPVSF
Mb1499|M.bovis_AF2122/97            ARYLGAIGMAAVEAHERELVAAAIEGLSGIDGVRILGPTSMRDRGSPVAF
Rv1464|M.tuberculosis_H37Rv         ARYLGAIGMAAVEAHERELVAAAIEGLSGIDGVRILGPTSMRDRGSPVAF
MMAR_2269|M.marinum_M               SRYLDAIGMDVIEAHERDLVAAAIEGLSAIEGVRIIGPTSMENRGSPVSF
MUL_1865|M.ulcerans_Agy99           SRYLDAIGMDVIEAHERDLVAAAIEGLSAIEGVRIIGPTSMENRGSPVSF
TH_3033|M.thermoresistible__bu      ARYLSAIGMDAVQAHEAELVAAALEGLSGIEQVRIIGPTSMELRGSPVSF
Mvan_2736|M.vanbaalenii_PYR-1       TRYLGGIGMSAVEEHEHRLVTATLEGLAAIPGVRIIGPATAERR-SPVAF
MAB_2746c|M.abscessus_ATCC_199      VDYLNAVGMEAVAAHEHQLVSAALAGLAGIEGVRIIGPTDNLDRGGAVSF
                                      ** .:** .:  **  **:*:: **: :  **::**     * ..*:*

Mflv_3674|M.gilvum_PYR-GCK          VVDGVHAHDVGQVLDDDGVAVRVGHHCAWPLHRRFGIAATARASFAVYNT
MSMEG_3125|M.smegmatis_MC2_155      VVDGVHAHDVGQVLDDDGVAVRVGHHCAWPLHRRFGIAATARASFAVYNT
MLBr_00596|M.leprae_Br4923          VVDGVHAHDIGQVLDDDGVAVRVGHHCALPLHRRFALAATARASFAVYNT
MAV_3315|M.avium_104                VVDGVHAHDVGQVLDDEGVAVRVGHHCALPLHRRFGLAATARASFAVYNT
Mb1499|M.bovis_AF2122/97            VVEGVHAHDVGQVLDDGGVAVRVGHHCALPLHRRFGLAATARASFAVYNT
Rv1464|M.tuberculosis_H37Rv         VVEGVHAHDVGQVLDDGGVAVRVGHHCALPLHRRFGLAATARASFAVYNT
MMAR_2269|M.marinum_M               VVDGVHAHDVGQVLDDEGVAVRVGHHCALPLHRKFGVAATARASFAVYNT
MUL_1865|M.ulcerans_Agy99           VVDGVHAHDVGQVLDDEGVAVRVGHHCALPLHRKFGVAATARASFAVYNT
TH_3033|M.thermoresistible__bu      VVDGVHAHDVGQVLDDDGVAVRVGHHCAWPLHQRFGIAATARASFAVYNT
Mvan_2736|M.vanbaalenii_PYR-1       VVDGVHAHDVGQVLDDDGVAVRVGHHCAAPLHRRFGIAATVRASFAVYNT
MAB_2746c|M.abscessus_ATCC_199      VVDGIHAHDLGQVLDDEGVAVRVGHHCAWPLHRRFGIAASARASFAVYNT
                                    **:*:****:****** *********** ***::*.:**:.*********

Mflv_3674|M.gilvum_PYR-GCK          VDEVDRLVAGVRRAVEFFGRE
MSMEG_3125|M.smegmatis_MC2_155      LDEVDRLVAGVKRAVEFFA--
MLBr_00596|M.leprae_Br4923          VDEVDRLVAGVLRALDFFGRE
MAV_3315|M.avium_104                AEEVDRLVAGVRRALDFFGGA
Mb1499|M.bovis_AF2122/97            ADEVDRLVAGVRRSRHFFGRA
Rv1464|M.tuberculosis_H37Rv         ADEVDRLVAGVRRSRHFFGRA
MMAR_2269|M.marinum_M               RDEVNRLLAGVQRSLNFFGRG
MUL_1865|M.ulcerans_Agy99           RDEVNRLLAGVQRSLNFFGRG
TH_3033|M.thermoresistible__bu      LDEVDRLVAGVRRAVEFFGDR
Mvan_2736|M.vanbaalenii_PYR-1       LDEVDRLIAGVQRAIEFFGRD
MAB_2746c|M.abscessus_ATCC_199      LDEVDRLTAGVRRAQEFFS--
                                     :**:** *** *: .**.