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M. thermoresistible (build 8) TH_1606 ()

annotation: POSSIBLE METHYLTRANSFERASE (METHYLASE)
coordinates: 3074446 - 3075249
length: 268

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_1606 - 100% (268) POSSIBLE METHYLTRANSFERASE (METHYLASE)
M. thermoresistible (build 8) TH_2193 - 5e-08 32.05% (156) CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8) TH_1636 - 4e-06 33.62% (116) POSSIBLE METHYLTRANSFERASE (METHYLASE)

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2655 - 4e-81 60.08% (263) methyltransferase (methylase)
M. gilvum PYR-GCK Mflv_4299 - 1e-122 84.41% (263) methyltransferase type 11
M. tuberculosis H37Rv Rv2622 - 4e-81 60.08% (263) methyltransferase (methylase)
M. leprae Br4923 MLBr_01713 - 2e-05 29.81% (161) hypothetical protein MLBr_01713
M. abscessus ATCC 19977 MAB_3364 - 2e-06 29.94% (157) hypothetical protein MAB_3364
M. marinum M MMAR_2078 - 2e-83 62.31% (260) methyltransferase
M. avium 104 MAV_3501 - 9e-82 59.77% (266) SAM-dependent methyltransferase
M. smegmatis MC2 155 MSMEG_5310 - 1e-105 71.70% (265) SAM-dependent methyltransferase
M. ulcerans Agy99 MUL_3266 - 2e-83 62.31% (260) methyltransferase
M. vanbaalenii PYR-1 Mvan_2049 - 1e-117 79.85% (263) methyltransferase type 11

CLUSTAL 2.0.9 multiple sequence alignment


Mb2655|M.bovis_AF2122/97            MANKRGNAGQ--PLPLSDRDDDHMQGHWLLARLGKRVLRPGGVE---LTR
Rv2622|M.tuberculosis_H37Rv         MANKRGNAGQ--PLPLSDRDDDHMQGHWLLARLGKRVLRPGGVE---LTR
MMAR_2078|M.marinum_M               MAGTQGESGQ--PLPLSNRSDDHLQGHWLLARLGKRVLRPGGVE---LTR
MUL_3266|M.ulcerans_Agy99           MAGTQGESGQ--PLPLSNRSDDHLQGHWLLARLGKRVLRPGGVE---LTR
MAV_3501|M.avium_104                MAANELRTGSEPPLPGSHRADEAVAGHWLLARLGKRVLRPGGVE---LTR
Mflv_4299|M.gilvum_PYR-GCK          -MADS-------PLPLAERSDADLPGHWLLARLGKRVLRPGGLE---LTT
Mvan_2049|M.vanbaalenii_PYR-1       -MADS-------PLPLAERSDADLPGHWLLARLGKRVLRPGGLE---LTT
TH_1606|M.thermoresistible__bu      MTAKS-------PLPLANRSDADLPGHWLLARLGKRVLRPGGLE---LTR
MSMEG_5310|M.smegmatis_MC2_155      MTSKS-------DLPLAQRPDADLPGHWLLARLGKRVLRPGGVE---LTT
MLBr_01713|M.leprae_Br4923          MSAFVPDVPN--RIPDDPSSIDSTAFHGMLTLTGERTIPDLDIENYWFRR
MAB_3364|M.abscessus_ATCC_1997      MNSHLTDPHP--ADPLRTSGPSAEDPDATLALTGERTVPGIAEENYWFRR
                                                  *           .  *:  *:*.:     *   :  

Mb2655|M.bovis_AF2122/97            TLLARAEVT----DADVLELAPGLGRTAAEILARNPRSYVGAESDPNAAN
Rv2622|M.tuberculosis_H37Rv         TLLARAEVT----DADVLELAPGLGRTAAEILARNPRSYVGAESDPNAAN
MMAR_2078|M.marinum_M               TLLARADVN----HADVLELAPGLGRTASEILARHPRSYVGAEADPDAAN
MUL_3266|M.ulcerans_Agy99           TLLARADVN----HADVLELAPGLGRTASEILARHPRSYVGAEADPDAAN
MAV_3501|M.avium_104                TLLSHAQLT----GADVVELAPGLGRTATEIVARAPRSYVGAEADPDAAN
Mflv_4299|M.gilvum_PYR-GCK          RLLTAARIQ----GADVVELGPGLGRTATDIVAERPRSYVGVDDTAAATE
Mvan_2049|M.vanbaalenii_PYR-1       RLLAAARIG----GSDVVELGPGLGRTASDIIAAQPRSYVGVDDTAAATE
TH_1606|M.thermoresistible__bu      RLLTAARVT----GADVVELGPGLGRTATDIVAAGPRSYVGVDDTAAATE
MSMEG_5310|M.smegmatis_MC2_155      RLLSAAGIT----GSDVVELGPGLGRTAVDIAAAEPRSYVGVDDNSTTSA
MLBr_01713|M.leprae_Br4923          HQVVYQWLAQRCTGCEVLEAGCGEG-YGADLIVDVAYRVIAVDYDEATVA
MAB_3364|M.abscessus_ATCC_1997      HEVVYERLSSLCAGRRVLEAGSGEG-YGADMLAQVAQHVIGLDYDESAIA
                                      :    :        *:* . * *  . :: .  .   :. :    :  

Mb2655|M.bovis_AF2122/97            LVRHVLAGRGD----VRVTDAADTGLSDASADVVIGEAMLTMQGNAAKHT
Rv2622|M.tuberculosis_H37Rv         LVRHVLAGRGD----VRVTDAADTGLSDASADVVIGEAMLTMQGNAAKHT
MMAR_2078|M.marinum_M               LVRTIVAGHGD----VRVADAADTGLPDSSADVVIGEAMLTMQGDAAKHA
MUL_3266|M.ulcerans_Agy99           LVRTIVAGRGD----VRVADAADTGLPDSSADVVIGEAMLTMQGDAAKHA
MAV_3501|M.avium_104                VVRGVLGDLGAHNAAVRVADAADTGLPDASGDVVIGEAMLTMQGDAAKRA
Mflv_4299|M.gilvum_PYR-GCK          QVRSIVAPVGG---KVVVADAASTGLPDGSADVVVGEAMLTMQGEKAKRA
Mvan_2049|M.vanbaalenii_PYR-1       NVKAIVAPVNG---AVVVADASTTGLPDGSADVVVGEAMLTMQGEKAKRA
TH_1606|M.thermoresistible__bu      AVRRIVEPVDG---KVVVANAADTGLPSGSADVVIGEAMLTMQGDRDKRA
MSMEG_5310|M.smegmatis_MC2_155      LLQSAVATSGG---RLVAADAAETGLDTGSADVVVGEAMLTMQGEKAKKA
MLBr_01713|M.leprae_Br4923          HVRSRYPRVQV-----MQANLIELPLADASVDVVVNFQVIEHLWNQAQ--
MAB_3364|M.abscessus_ATCC_1997      HVKARYPRVDM-----RAGNLADLPLADGSVDVVVNFQVIEHLWDQGQ--
                                     ::                :     *  .* ***:.  ::    :  :  

Mb2655|M.bovis_AF2122/97            IVAEAARVLRPGGRYAIHELALVPDDVAEQVRTDLRQSLARALKVNARPL
Rv2622|M.tuberculosis_H37Rv         IVAEAARVLRPGGRYAIHELALVPDDVAEQVRTDLRQSLARALKVNARPL
MMAR_2078|M.marinum_M               IVAEAARVLRPHGRYAIHELALTPDDVPEEISTEVRQALARSIKVNARPL
MUL_3266|M.ulcerans_Agy99           IVAEAARVLRPHGRYAIHELALTPDDVPEEISTEVRQALARSIKVNARPL
MAV_3501|M.avium_104                IVAEAARVLRPGGRYAIHELALTPDTVSAEVSTDIRRALARAIKVNARPL
Mflv_4299|M.gilvum_PYR-GCK          IIGEAFRVLRPGGRYAIHELGLSPDDLSQGIKDDIRRDMSRAIKVNARPL
Mvan_2049|M.vanbaalenii_PYR-1       IIAEAFRVLRPGGRYAIHELGLTPDDLSQDIKDDIRREMSRAIKVNARPL
TH_1606|M.thermoresistible__bu      IVNEAFRVLRPGGRYAIHELGLQPDSLPQDTKDQIRKDMARAIKVNARPL
MSMEG_5310|M.smegmatis_MC2_155      IVDEAFRVLRPGGRYAIHELGLMPDDLSDGIKDDIRKEMARAIKVNARPL
MLBr_01713|M.leprae_Br4923          FVSECARVLRPSGLLMVSTPNRITFSPGRDTSINPFHTRELNADELTQLL
MAB_3364|M.abscessus_ATCC_1997      FIRECARVLRPGGSLLISTPNRITFSPGRDTPLNPFHTRELNGAELTELL
                                    :: *. ***** *   :      .         :  :         :. *

Mb2655|M.bovis_AF2122/97            TVAEWSHLLAG---HGLVVEHVVTAS-MALLQPRRVIADEGLLGALRFAG
Rv2622|M.tuberculosis_H37Rv         TVAEWSHLLAG---HGLVVEHVVTAS-MALLQPRRVIADEGLLGALRFAG
MMAR_2078|M.marinum_M               TVAEWSQLLAG---HGLVVSHVATAP-MALLQPRRIIADEGLLGALRFAK
MUL_3266|M.ulcerans_Agy99           TVAEWSQLLAG---HGLVVSHVATAP-MALLQPRRIIADEGLLGALRFAK
MAV_3501|M.avium_104                TVAEWSALLAE---HGLVVDHVATAP-MALLQPRRLVSDEGLFGALRFAR
Mflv_4299|M.gilvum_PYR-GCK          TSAEWTALLTD---AGFKIESVDHAP-MALLNPARVLADEGPLGALRIVG
Mvan_2049|M.vanbaalenii_PYR-1       TIAEWTALLTE---AGFQVETVDQAP-MALLSPARVLADEGLFGALRIVG
TH_1606|M.thermoresistible__bu      TASEWVNLLTD---AGFEVVSVDHAK-MALLNPGRVLADEGLFGALRIVG
MSMEG_5310|M.smegmatis_MC2_155      TVAEWTDLLTS---AGFEVRSVDLAP-MALLQPKRVVADEGFLGALRIVF
MLBr_01713|M.leprae_Br4923          ITADFSEVAMYGLFHGPRLKEMDARHGGSIIDAQIARAVSNAPWPPELVA
MAB_3364|M.abscessus_ATCC_1997      EENGFSLESMNGVFHGPRLRELDAKYGGSIIDAQIERAVAGAPWPQELLA
                                        :          *  :  :      :::..    :  .   . .:  

Mb2655|M.bovis_AF2122/97            NLLIHRAARRRVLLMRH--TFRRHRERLTAVAIVAHKPHVDS--
Rv2622|M.tuberculosis_H37Rv         NLLIHRAARRRVLLMRH--TFRRHRERLTAVAIVAHKPHVDS--
MMAR_2078|M.marinum_M               NLLTQPAARKRVLMMRS--TFRKHRDRMAAVAIVAYKPSASGS-
MUL_3266|M.ulcerans_Agy99           NLLTQPAARKRVLMMRS--TFRKHRDRMAAVAIVAYKPSASGS-
MAV_3501|M.avium_104                NVLVHRDARKRVLTMRR--TFRKHRRQLAAVAIVAHKPTASQTG
Mflv_4299|M.gilvum_PYR-GCK          NLIRRPAARKRVIGMRK--TFQRYRRSLTAVAVVGVVPGQ----
Mvan_2049|M.vanbaalenii_PYR-1       NMIRRPAARRRVLGMRA--TFARYRRSLTAVAVVGVVPGQ----
TH_1606|M.thermoresistible__bu      NLIRRPAARKRVIGMRK--TFQRYRHSLTAIAVVGVVPEK----
MSMEG_5310|M.smegmatis_MC2_155      NALTHPAARKRVLGMRR--TFNRYRDELTAVAIVAVVPTESK--
MLBr_01713|M.leprae_Br4923          DVAAVTAADFDIIEASAGPEASDGRDVDESLDLIAIAVRR----
MAB_3364|M.abscessus_ATCC_1997      DITGLTTEDFEIVDAGE-------RDIDASLDLVAIAVIP----
                                    :          ::           *    :: ::.

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_1606		-	100% (268)	POSSIBLE METHYLTRANSFERASE (METHYLASE)
M. thermoresistible (build 8)	TH_2193	-	5e-08	32.05% (156)	CONSERVED HYPOTHETICAL PROTEIN
M. thermoresistible (build 8)	TH_1636	-	4e-06	33.62% (116)	POSSIBLE METHYLTRANSFERASE (METHYLASE)