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ADSPLPLAERSDADLPGHWLLARLGKRVLRPGGLELTTRLLTAARIQGADVVELGPGLGRTATDIVAERP RSYVGVDDTAAATEQVRSIVAPVGGKVVVADAASTGLPDGSADVVVGEAMLTMQGEKAKRAIIGEAFRVL RPGGRYAIHELGLSPDDLSQGIKDDIRRDMSRAIKVNARPLTSAEWTALLTDAGFKIESVDHAPMALLNP ARVLADEGPLGALRIVGNLIRRPAARKRVIGMRKTFQRYRRSLTAVAVVGVVPGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4299 | - | - | 100% (266) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_4260 | - | 9e-08 | 31.52% (165) | methyltransferase type 11 |
| M. gilvum PYR-GCK | Mflv_1100 | - | 4e-05 | 25.90% (139) | methyltransferase type 11 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2655 | - | 2e-83 | 60.46% (263) | methyltransferase (methylase) |
| M. tuberculosis H37Rv | Rv2622 | - | 2e-83 | 60.46% (263) | methyltransferase (methylase) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3364 | - | 1e-06 | 30.00% (160) | hypothetical protein MAB_3364 |
| M. marinum M | MMAR_2078 | - | 1e-84 | 61.92% (260) | methyltransferase |
| M. avium 104 | MAV_3501 | - | 4e-85 | 60.53% (266) | SAM-dependent methyltransferase |
| M. smegmatis MC2 155 | MSMEG_5310 | - | 1e-109 | 76.63% (261) | SAM-dependent methyltransferase |
| M. thermoresistible (build 8) | TH_1606 | - | 1e-123 | 84.41% (263) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. ulcerans Agy99 | MUL_3266 | - | 9e-85 | 61.92% (260) | methyltransferase |
| M. vanbaalenii PYR-1 | Mvan_2049 | - | 1e-130 | 87.97% (266) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2655|M.bovis_AF2122/97 MANKRGNAGQ--PLPLSDRDDD------HMQGHWLLARLGKRVLRPGGVE
Rv2622|M.tuberculosis_H37Rv MANKRGNAGQ--PLPLSDRDDD------HMQGHWLLARLGKRVLRPGGVE
MMAR_2078|M.marinum_M MAGTQGESGQ--PLPLSNRSDD------HLQGHWLLARLGKRVLRPGGVE
MUL_3266|M.ulcerans_Agy99 MAGTQGESGQ--PLPLSNRSDD------HLQGHWLLARLGKRVLRPGGVE
MAV_3501|M.avium_104 MAANELRTGSEPPLPGSHRADE------AVAGHWLLARLGKRVLRPGGVE
Mflv_4299|M.gilvum_PYR-GCK -MADS-------PLPLAERSDA------DLPGHWLLARLGKRVLRPGGLE
Mvan_2049|M.vanbaalenii_PYR-1 -MADS-------PLPLAERSDA------DLPGHWLLARLGKRVLRPGGLE
TH_1606|M.thermoresistible__bu MTAKS-------PLPLANRSDA------DLPGHWLLARLGKRVLRPGGLE
MSMEG_5310|M.smegmatis_MC2_155 MTSKS-------DLPLAQRPDA------DLPGHWLLARLGKRVLRPGGVE
MAB_3364|M.abscessus_ATCC_1997 MNSHLTDPHPADPLRTSGPSAEDPDATLALTGERTVPGIAEENYWFRRHE
* : : *. :. :.:. *
Mb2655|M.bovis_AF2122/97 LTRTLLARAEVTDADVLELAPGLGRTAAEILARNPRSYVGAESDPNAANL
Rv2622|M.tuberculosis_H37Rv LTRTLLARAEVTDADVLELAPGLGRTAAEILARNPRSYVGAESDPNAANL
MMAR_2078|M.marinum_M LTRTLLARADVNHADVLELAPGLGRTASEILARHPRSYVGAEADPDAANL
MUL_3266|M.ulcerans_Agy99 LTRTLLARADVNHADVLELAPGLGRTASEILARHPRSYVGAEADPDAANL
MAV_3501|M.avium_104 LTRTLLSHAQLTGADVVELAPGLGRTATEIVARAPRSYVGAEADPDAANV
Mflv_4299|M.gilvum_PYR-GCK LTTRLLTAARIQGADVVELGPGLGRTATDIVAERPRSYVGVDDTAAATEQ
Mvan_2049|M.vanbaalenii_PYR-1 LTTRLLAAARIGGSDVVELGPGLGRTASDIIAAQPRSYVGVDDTAAATEN
TH_1606|M.thermoresistible__bu LTRRLLTAARVTGADVVELGPGLGRTATDIVAAGPRSYVGVDDTAAATEA
MSMEG_5310|M.smegmatis_MC2_155 LTTRLLSAAGITGSDVVELGPGLGRTAVDIAAAEPRSYVGVDDNSTTSAL
MAB_3364|M.abscessus_ATCC_1997 VVYERLS-SLCAGRRVLEAGSGEG-YGADMLAQVAQHVIGLDYDESAIAH
:. *: : *:* ..* * . :: * .: :* : :
Mb2655|M.bovis_AF2122/97 VRHVLAGRGD----VRVTDAADTGLSDASADVVIGEAMLTMQGNAAKHTI
Rv2622|M.tuberculosis_H37Rv VRHVLAGRGD----VRVTDAADTGLSDASADVVIGEAMLTMQGNAAKHTI
MMAR_2078|M.marinum_M VRTIVAGHGD----VRVADAADTGLPDSSADVVIGEAMLTMQGDAAKHAI
MUL_3266|M.ulcerans_Agy99 VRTIVAGRGD----VRVADAADTGLPDSSADVVIGEAMLTMQGDAAKHAI
MAV_3501|M.avium_104 VRGVLGDLGAHNAAVRVADAADTGLPDASGDVVIGEAMLTMQGDAAKRAI
Mflv_4299|M.gilvum_PYR-GCK VRSIVAPVGG---KVVVADAASTGLPDGSADVVVGEAMLTMQGEKAKRAI
Mvan_2049|M.vanbaalenii_PYR-1 VKAIVAPVNG---AVVVADASTTGLPDGSADVVVGEAMLTMQGEKAKRAI
TH_1606|M.thermoresistible__bu VRRIVEPVDG---KVVVANAADTGLPSGSADVVIGEAMLTMQGDRDKRAI
MSMEG_5310|M.smegmatis_MC2_155 LQSAVATSGG---RLVAADAAETGLDTGSADVVVGEAMLTMQGEKAKKAI
MAB_3364|M.abscessus_ATCC_1997 VKARYPRVDM-----RAGNLADLPLADGSVDVVVNFQVIEHLWDQGQ--F
:: . . : : * .* ***:. :: : : :
Mb2655|M.bovis_AF2122/97 VAEAARVLRPGGRYAIHELALVPDDVAEQVRTDLRQSLARALKVNARPLT
Rv2622|M.tuberculosis_H37Rv VAEAARVLRPGGRYAIHELALVPDDVAEQVRTDLRQSLARALKVNARPLT
MMAR_2078|M.marinum_M VAEAARVLRPHGRYAIHELALTPDDVPEEISTEVRQALARSIKVNARPLT
MUL_3266|M.ulcerans_Agy99 VAEAARVLRPHGRYAIHELALTPDDVPEEISTEVRQALARSIKVNARPLT
MAV_3501|M.avium_104 VAEAARVLRPGGRYAIHELALTPDTVSAEVSTDIRRALARAIKVNARPLT
Mflv_4299|M.gilvum_PYR-GCK IGEAFRVLRPGGRYAIHELGLSPDDLSQGIKDDIRRDMSRAIKVNARPLT
Mvan_2049|M.vanbaalenii_PYR-1 IAEAFRVLRPGGRYAIHELGLTPDDLSQDIKDDIRREMSRAIKVNARPLT
TH_1606|M.thermoresistible__bu VNEAFRVLRPGGRYAIHELGLQPDSLPQDTKDQIRKDMARAIKVNARPLT
MSMEG_5310|M.smegmatis_MC2_155 VDEAFRVLRPGGRYAIHELGLMPDDLSDGIKDDIRKEMARAIKVNARPLT
MAB_3364|M.abscessus_ATCC_1997 IRECARVLRPGGSLLISTPNRITFSPGRDTPLNP---------FHTRELN
: *. ***** * * . : .::* *.
Mb2655|M.bovis_AF2122/97 VAEWSHLLAGHGLVVEHVV----TASMALLQPRR------VIADEGLLGA
Rv2622|M.tuberculosis_H37Rv VAEWSHLLAGHGLVVEHVV----TASMALLQPRR------VIADEGLLGA
MMAR_2078|M.marinum_M VAEWSQLLAGHGLVVSHVA----TAPMALLQPRR------IIADEGLLGA
MUL_3266|M.ulcerans_Agy99 VAEWSQLLAGHGLVVSHVA----TAPMALLQPRR------IIADEGLLGA
MAV_3501|M.avium_104 VAEWSALLAEHGLVVDHVA----TAPMALLQPRR------LVSDEGLFGA
Mflv_4299|M.gilvum_PYR-GCK SAEWTALLTDAGFKIESVD----HAPMALLNPAR------VLADEGPLGA
Mvan_2049|M.vanbaalenii_PYR-1 IAEWTALLTEAGFQVETVD----QAPMALLSPAR------VLADEGLFGA
TH_1606|M.thermoresistible__bu ASEWVNLLTDAGFEVVSVD----HAKMALLNPGR------VLADEGLFGA
MSMEG_5310|M.smegmatis_MC2_155 VAEWTDLLTSAGFEVRSVD----LAPMALLQPKR------VVADEGFLGA
MAB_3364|M.abscessus_ATCC_1997 GAELTELLEENGFSLESMNGVFHGPRLRELDAKYGGSIIDAQIERAVAGA
:* ** *: : : . : *.. :.. **
Mb2655|M.bovis_AF2122/97 LRFAGNLLIHRAARRRVLLMRHTFRRHRERLTAVAIVAHKPHVDS--
Rv2622|M.tuberculosis_H37Rv LRFAGNLLIHRAARRRVLLMRHTFRRHRERLTAVAIVAHKPHVDS--
MMAR_2078|M.marinum_M LRFAKNLLTQPAARKRVLMMRSTFRKHRDRMAAVAIVAYKPSASGS-
MUL_3266|M.ulcerans_Agy99 LRFAKNLLTQPAARKRVLMMRSTFRKHRDRMAAVAIVAYKPSASGS-
MAV_3501|M.avium_104 LRFARNVLVHRDARKRVLTMRRTFRKHRRQLAAVAIVAHKPTASQTG
Mflv_4299|M.gilvum_PYR-GCK LRIVGNLIRRPAARKRVIGMRKTFQRYRRSLTAVAVVGVVPGQ----
Mvan_2049|M.vanbaalenii_PYR-1 LRIVGNMIRRPAARRRVLGMRATFARYRRSLTAVAVVGVVPGQ----
TH_1606|M.thermoresistible__bu LRIVGNLIRRPAARKRVIGMRKTFQRYRHSLTAIAVVGVVPEK----
MSMEG_5310|M.smegmatis_MC2_155 LRIVFNALTHPAARKRVLGMRRTFNRYRDELTAVAIVAVVPTESK--
MAB_3364|M.abscessus_ATCC_1997 PWPQELLADITGLTTEDFEIVDAGERDIDASLDLVAIAVIP------
. : : : : :. :. *