For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
NDPRRVLHPAAAALPSASALGAQPKAAVIGGGIAGLAAATSLAERGVAVRLYERQSYLGGRVGGWQDTLD DGTTVAMNRGFHAFFRQYYNLRGILSRIDPSLSMLSPLTDYPLVDALGRRDTFRGLPRTPPFNAMAFALR SPTFRVRDLIRLDARAAAPLAAVSVPGTYDELDDQDAESFLRDINFPDAARHLAFEVFSRSFFTRPAALS AAELATMFHIYFLGSSEGLVFDVATSNFDVALWNPLASYLERLGAHVHTGTAVDSVTATSQNSFIVTDGA GDENEVDGVVLATDVSALQSIVSSSESLGDPEWREKIHRMGTALPFVVQRLWLDRPVRGDRPAFLGTGGL PPLDNISVLERYEHEARDWCARTGGSVVELHAYSVDQDSPELRRALISRLHDLYPETVDATIVGEKTLCR NDCPRLAPGDFAQRPTVRTPHPGLALAGDGIRIDLPVALMERAATTGIAAANSLLAHFGVTGHDMYTVPV RGRSPVLRHLANRVERRVLR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1844 | - | - | 100% (511) | amine oxidase |
| M. gilvum PYR-GCK | Mflv_4516 | - | 2e-08 | 25.75% (466) | amine oxidase |
| M. gilvum PYR-GCK | Mflv_4557 | - | 5e-06 | 32.91% (79) | hypothetical protein Mflv_4557 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2659 | - | 2e-05 | 22.56% (492) | putative flavin-containing monoamine oxidase AofH |
| M. marinum M | MMAR_4806 | crtI | 9e-05 | 43.33% (60) | phytoene dehydrogenase CrtI |
| M. avium 104 | MAV_3890 | - | 1e-178 | 64.14% (502) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2344 | - | 1e-174 | 62.62% (503) | dehydrogenase |
| M. thermoresistible (build 8) | TH_1483 | - | 0.0 | 68.88% (511) | dehydrogenase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1580 | - | 0.0 | 70.89% (474) | amine oxidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1844|M.gilvum_PYR-GCK ----MNDPRRVLHPAAAALPSASALGAQPKAAVIGGGIAGLAAATSLAER
Mvan_1580|M.vanbaalenii_PYR-1 ------------------------------MVVVGGGIAGLAAATGLAER
TH_1483|M.thermoresistible__bu ----LTDPRRVHHHAPPGLPDARGLARRPHVVVVGAGIAGLAAATGLAER
MAV_3890|M.avium_104 MTAGATDRRRRILPAPTGLPDAGALPSRPRVAVVGGGIAGLTAATGLAER
MSMEG_2344|M.smegmatis_MC2_155 --------MQRTHTAPRGLPHAGELPRRPRVVVVGAGIAGLAAATGMAER
MMAR_4806|M.marinum_M --------------------MRTIEGTADHVVVIGAGLAGLATALHLAGR
MAB_2659|M.abscessus_ATCC_1997 ---------------MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNM
.::*.*:***::* :.
Mflv_1844|M.gilvum_PYR-GCK GVAVRLYERQSYLGGRVG-----GWQDTLDDGTT--VAMNRGFHAFFRQY
Mvan_1580|M.vanbaalenii_PYR-1 GVAVEVIEKHGYLGGRVG-----GWSDTLADGTP--VAMNRGFHAFFRQY
TH_1483|M.thermoresistible__bu GVTVDVVEQAGYLGGRVG-----GWTEDIGPDVPGGAAMNRGFHAFFRQY
MAV_3890|M.avium_104 GVAVEVIEREHYLGGRVG-----GWTEHHDGTDL---AMNRGFHAFFRQY
MSMEG_2344|M.smegmatis_MC2_155 GVEVTVIERENYLGGRVG-----GWSEQHDGAEY---AMNRGFHAFFRQY
MMAR_4806|M.marinum_M GRSVTVVEREAWPGGRAGRLDIDGYRIDTGPTVLTMPDLIDEVFAAVGET
MAB_2659|M.abscessus_ATCC_1997 GVSVLVIDARERVGGRSF------------TGEVAGVKVDLGATWVAKRH
* * : : *** : .
Mflv_1844|M.gilvum_PYR-GCK YNLRGILSRIDPSLSMLSPLTDYPLVDALGRR-----DTFRGLPRTP-PF
Mvan_1580|M.vanbaalenii_PYR-1 YNLRALLRRSDPGLSALTPVEDYPLIDGAGRR-----DTFRGLPQTP-PL
TH_1483|M.thermoresistible__bu YNLRTLLRRIDPGLGMLTPVDDYPLVDAHGRR-----DTFRGLPKTP-PF
MAV_3890|M.avium_104 YNLRALLARLDPRLRMLVPVNDYPLIDAAGRR-----DSFRGLPRTP-PL
MSMEG_2344|M.smegmatis_MC2_155 YNLRALLARVDPQLRMLTPVEDYPLIDGEGRR-----ESFRRLPHTP-PW
MMAR_4806|M.marinum_M ISDRLELLPVDPAYTAMFADGSSIDVHCDADRMVAAIENFAGPEQATGYL
MAB_2659|M.abscessus_ATCC_1997 TAIRDLMDRLGCSLTPQYDEGVNLLWMAGKRK------TWTGTLPTVDPV
* : . : .: :
Mflv_1844|M.gilvum_PYR-GCK NAMAFALRSPTFRVRDLIRLDARAAAPLAAVSVPGTYDELDDQDAESFLR
Mvan_1580|M.vanbaalenii_PYR-1 NALAFALRSPTFRLRDLVRLDAKAAAPLAAVSVPETYDLLDGRDAETFLR
TH_1483|M.thermoresistible__bu NAMAFALRSPTFRLRDLIRLNARAAAPLAAVELPGIYRHLDDTDAESFLR
MAV_3890|M.avium_104 NAMAFAVRSPTFRLRDFARIDARAAAPLAAVSVPGTYRRLDHIDAATFLE
MSMEG_2344|M.smegmatis_MC2_155 NALWFALRSPTFRLRDLMRLDAKAAAPLAAVSVPGIYDRLDHIDAETFLK
MMAR_4806|M.marinum_M RLREWLTRLYRIEFAGFIGSNFDSPLSLLTPQLARLAAAGGFRNWDSMVK
MAB_2659|M.abscessus_ATCC_1997 DLEDLGR----------ITIEMGKLLETINVDAAWKSPNADQLDSISFGE
: . . . : :: .
Mflv_1844|M.gilvum_PYR-GCK -DINFPDAARHLAFEVFSRSFFTRPAALSAAELATMFHIYFLGSSEGLVF
Mvan_1580|M.vanbaalenii_PYR-1 -DINFPEAARHLAFEVFARSFFARPETLSAGELVTMFHIYFLGSSEGLIF
TH_1483|M.thermoresistible__bu -AINFPPAARHLAFEVFSRSFFAQPSQLSAAELATMFHIYFLGSSEGLVF
MAV_3890|M.avium_104 -DIRFPEAARHLAFEVFSRSFFADPAKLSAAELATMFHIYFLGSAEGLIF
MSMEG_2344|M.smegmatis_MC2_155 -DINFPPAARHLAFEVFSRSFFADPSNLSAAELATMFHIYFLGSSEGLVF
MMAR_4806|M.marinum_M RHITDPRLRRVFTFQSLYAGVAP------QDALAAYAVIAYMDTISGVFF
MAB_2659|M.abscessus_ATCC_1997 WLSQQQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQAVGGLDHMLA
:: : . * . : :. . :.
Mflv_1844|M.gilvum_PYR-GCK DVA---TSNFDVALWNPLASYLERLGAHVHTGTAVDSVTATS--QNSFIV
Mvan_1580|M.vanbaalenii_PYR-1 DVA---NANFDVALWNPLRRYLEGRGVVFHTGAEVDSVTVA----DEVTV
TH_1483|M.thermoresistible__bu DVV---NANFDVALWNPLRDQLESRGVRFHTGVGVRAVDAG----ARFRV
MAV_3890|M.avium_104 DVP---SANYDSALWQPLRSYLEQRHVRFRLGTSVGSID----AANRFAV
MSMEG_2344|M.smegmatis_MC2_155 DVP---TSNYDTALWEPLRRYLHEHGVRFHLGASVTRIDPVTTSPDAFAV
MMAR_4806|M.marinum_M PRG---GVR---ALPDALAAAAACAGVQFHYGSQVSELERDD--ARITAV
MAB_2659|M.abscessus_ATCC_1997 VEHGQQEYRVTETTQEIAKRLAAQIGDQIVLNTRVRQISQDD---NGVTV
. : : . . * : *
Mflv_1844|M.gilvum_PYR-GCK TDGAGDENEVDGVVLATDVSALQSIVSSSESLGDPEWREKIHRMGTALPF
Mvan_1580|M.vanbaalenii_PYR-1 TGSRAQVWSADAAVLATDPGSLRRVVAASPGLGDPSWRERVAAIGTAPPF
TH_1483|M.thermoresistible__bu SCDSGDELTADGVVLATDVTGLQRIVAASPGLGDAGWRDRIAGLHTAPPF
MAV_3890|M.avium_104 HTDTDEELEVDAVVLATDVAGLQRIVAASRGLANGEWRDRIAGLRTAPPF
MSMEG_2344|M.smegmatis_MC2_155 HTDSGERLDADAVVLAADIAGLQRIVASSPGLGDDRWRARVQGLRTAPPF
MMAR_4806|M.marinum_M RTDRGERIACDAVVLTTELPTTYRLLGRTP--------RRLRRLRAAPSA
MAB_2659|M.abscessus_ATCC_1997 STDSG--VINAKYAIVTAAPEHRAYIEYQPALP-----AKIEGLTTSFPM
. .:.: : :: : :: .
Mflv_1844|M.gilvum_PYR-GCK VVQRLWLDRPVRGDRPAFLGTG--GLPPLDNISVLERYEHEARDWCARTG
Mvan_1580|M.vanbaalenii_PYR-1 VVLRLWLDRPVRHDRAAFVGTG--GRDPLDNISVLERYEREAAQWCSRTG
TH_1483|M.thermoresistible__bu VVHRLWLDRPVAPDRPPFLGTG--GWSPLDNVSVLETYEHQARDWARCTG
MAV_3890|M.avium_104 AVHRFWLDRPVSPRRPAFLGTA--GHKPLDNISVLDRYEREARAWAGAHH
MSMEG_2344|M.smegmatis_MC2_155 AVHRLWLDRPVTADRPAFMGTA--GHKPLDNISVLERYERQSAQWARDNG
MMAR_4806|M.marinum_M VVVHAGCRSASTASEPAAHHTILFGQAWEQTFTDIIRDGRLMRDPSLLVT
MAB_2659|M.abscessus_ATCC_1997 GALS---KAFVAYDKPFWRAEGLSGEALTDTAPVFITFDVSPSDDGPGIL
. .. * :. . :
Mflv_1844|M.gilvum_PYR-GCK GSVVELHAYSVDQDSPELRRALISRLHDLYPETVDATIVGEKTLCRNDCP
Mvan_1580|M.vanbaalenii_PYR-1 GSVVELHAYSVRDEDADVRDRLIARMHELYPETATASIVAERLLRRDDCP
TH_1483|M.thermoresistible__bu GSVVELHSYAVTEPTDGLRDALLDRLHALYPETADAGIVAERVLCRQDCP
MAV_3890|M.avium_104 GSVVELHSYALDSAPSGA--AALRELRRIYPETAAAQIVHETLLHRSDCP
MSMEG_2344|M.smegmatis_MC2_155 GSAVELHAYALDTAESGP--GALAQLHRLYPETATAEPVFERVLVRDDCP
MMAR_4806|M.marinum_M RPTAGDPALAPPGRDLLYLLAPAPNLTAGRVDWGSAGGSYAQSMIDTVAS
MAB_2659|M.abscessus_ATCC_1997 MVFCTARVYDGFGPEVRR-KLVLKQLVDLYGEQANTPIDYIDHCWG-TEP
.: : : .
Mflv_1844|M.gilvum_PYR-GCK RLAPGDFAQRPTVRTPHPGLALAGDGIRIDLPVALMERAATTG-IAAAN-
Mvan_1580|M.vanbaalenii_PYR-1 RFAPGDFADRPTVSTPDPRLKLAGDGIRIDLPVALMERAATTG-WTAAN-
TH_1483|M.thermoresistible__bu RFAPGDHAGRPGVAGPHPALALAGDGIRIDLPVALMERAATTG-WSAAN-
MAV_3890|M.avium_104 LFAPGGYPHRPTVVTPTPGLLLASDTVRIDLPVALMERAATTG-WSAAN-
MSMEG_2344|M.smegmatis_MC2_155 LFAPGSHADRPGVVTGVPGLVLAGDGIRLDLPAALMERAATTG-WAAAN-
MMAR_4806|M.marinum_M RLLP-DLRDSVELLDVVTPLDWARQGMAAGTPFALAHTFGQTGPFRPANT
MAB_2659|M.abscessus_ATCC_1997 FAAGGPHPAAPPFASVN-----YGEALREPHGRIHWAGTETAGEWVGTMN
. : : :* :
Mflv_1844|M.gilvum_PYR-GCK -------SLLAHFGVTGHDMYTVPVRGRSPVLRHLANRVERRVLR-----
Mvan_1580|M.vanbaalenii_PYR-1 -------ELLTGFGLAGHTLHTVPNRGRSAVLRRLATSAGG--VR-----
TH_1483|M.thermoresistible__bu -------RLLTHFGLAGHPLYTVPTRGRSAALRRLARREVR-QVR-----
MAV_3890|M.avium_104 -------HLLKRWGLAGHPLVTVPTEGRSRLLRWLANREGATRS------
MSMEG_2344|M.smegmatis_MC2_155 -------VLLNRWGVAGHALRSVPTAGRFAPLRWLATREERRAS------
MMAR_4806|M.marinum_M VRGIDNAVLAGSSTVPGVGVPTTLISGRLAADRITGNTTRSIRHLDLKAQ
MAB_2659|M.abscessus_ATCC_1997 ----------------GAILMGLHTADQIAQQLGVTGEVSK---------
* : .:
Mflv_1844|M.gilvum_PYR-GCK --
Mvan_1580|M.vanbaalenii_PYR-1 --
TH_1483|M.thermoresistible__bu --
MAV_3890|M.avium_104 --
MSMEG_2344|M.smegmatis_MC2_155 --
MMAR_4806|M.marinum_M LS
MAB_2659|M.abscessus_ATCC_1997 --