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MTAGATDRRRRILPAPTGLPDAGALPSRPRVAVVGGGIAGLTAATGLAERGVAVEVIEREHYLGGRVGGW TEHHDGTDLAMNRGFHAFFRQYYNLRALLARLDPRLRMLVPVNDYPLIDAAGRRDSFRGLPRTPPLNAMA FAVRSPTFRLRDFARIDARAAAPLAAVSVPGTYRRLDHIDAATFLEDIRFPEAARHLAFEVFSRSFFADP AKLSAAELATMFHIYFLGSAEGLIFDVPSANYDSALWQPLRSYLEQRHVRFRLGTSVGSIDAANRFAVHT DTDEELEVDAVVLATDVAGLQRIVAASRGLANGEWRDRIAGLRTAPPFAVHRFWLDRPVSPRRPAFLGTA GHKPLDNISVLDRYEREARAWAGAHHGSVVELHSYALDSAPSGAAALRELRRIYPETAAAQIVHETLLHR SDCPLFAPGGYPHRPTVVTPTPGLLLASDTVRIDLPVALMERAATTGWSAANHLLKRWGLAGHPLVTVPT EGRSRLLRWLANREGATRS
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_3890 | - | - | 100% (509) | dehydrogenase |
M. avium 104 | MAV_3885 | - | 2e-08 | 27.74% (292) | phytoene dehydrogenase |
M. avium 104 | MAV_3029 | - | 2e-06 | 42.31% (52) | hypothetical protein MAV_3029 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_1844 | - | 1e-178 | 64.14% (502) | amine oxidase |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_2659 | - | 6e-05 | 28.57% (161) | putative flavin-containing monoamine oxidase AofH |
M. marinum M | MMAR_4806 | crtI | 5e-07 | 26.44% (329) | phytoene dehydrogenase CrtI |
M. smegmatis MC2 155 | MSMEG_2344 | - | 0.0 | 71.74% (499) | dehydrogenase |
M. thermoresistible (build 8) | TH_1483 | - | 0.0 | 68.12% (505) | dehydrogenase |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_1580 | - | 1e-174 | 65.90% (481) | amine oxidase |
CLUSTAL 2.0.9 multiple sequence alignment MAV_3890|M.avium_104 MTAGATDRRRRILPAPTGLPDAGALPSRPRVAVVGGGIAGLTAATGLAER MSMEG_2344|M.smegmatis_MC2_155 --------MQRTHTAPRGLPHAGELPRRPRVVVVGAGIAGLAAATGMAER Mflv_1844|M.gilvum_PYR-GCK ----MNDPRRVLHPAAAALPSASALGAQPKAAVIGGGIAGLAAATSLAER Mvan_1580|M.vanbaalenii_PYR-1 ------------------------------MVVVGGGIAGLAAATGLAER TH_1483|M.thermoresistible__bu ----LTDPRRVHHHAPPGLPDARGLARRPHVVVVGAGIAGLAAATGLAER MMAR_4806|M.marinum_M --------------------MRTIEGTADHVVVIGAGLAGLATALHLAGR MAB_2659|M.abscessus_ATCC_1997 ---------------MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNM .::*.*:***::* :. MAV_3890|M.avium_104 GVAVEVIEREHYLGGRVG-----GWTEHHDGTDL---AMNRGFHAFFRQY MSMEG_2344|M.smegmatis_MC2_155 GVEVTVIERENYLGGRVG-----GWSEQHDGAEY---AMNRGFHAFFRQY Mflv_1844|M.gilvum_PYR-GCK GVAVRLYERQSYLGGRVG-----GWQDTLDDGTT--VAMNRGFHAFFRQY Mvan_1580|M.vanbaalenii_PYR-1 GVAVEVIEKHGYLGGRVG-----GWSDTLADGTP--VAMNRGFHAFFRQY TH_1483|M.thermoresistible__bu GVTVDVVEQAGYLGGRVG-----GWTEDIGPDVPGGAAMNRGFHAFFRQY MMAR_4806|M.marinum_M GRSVTVVEREAWPGGRAGRLDIDGYRIDTGPTVLTMPDLIDEVFAAVGET MAB_2659|M.abscessus_ATCC_1997 GVSVLVIDARERVGGRSF------------TGEVAGVKVDLGATWVAKRH * * : : *** : . MAV_3890|M.avium_104 YNLRALLARLDPRLRMLVPVNDYPLIDAAGRR-----DSFRGLPRTP-PL MSMEG_2344|M.smegmatis_MC2_155 YNLRALLARVDPQLRMLTPVEDYPLIDGEGRR-----ESFRRLPHTP-PW Mflv_1844|M.gilvum_PYR-GCK YNLRGILSRIDPSLSMLSPLTDYPLVDALGRR-----DTFRGLPRTP-PF Mvan_1580|M.vanbaalenii_PYR-1 YNLRALLRRSDPGLSALTPVEDYPLIDGAGRR-----DTFRGLPQTP-PL TH_1483|M.thermoresistible__bu YNLRTLLRRIDPGLGMLTPVDDYPLVDAHGRR-----DTFRGLPKTP-PF MMAR_4806|M.marinum_M ISDRLELLPVDPAYTAMFADGSSIDVHCDADRMVAAIENFAGPEQATGYL MAB_2659|M.abscessus_ATCC_1997 TAIRDLMDRLGCSLTPQYDEGVNLLWMAGKRK------TWTGTLPTVDPV * : . : .: : MAV_3890|M.avium_104 NAMAFAVRSPTFRLRDFARIDARAAAPLAAVSVPGTYRRLDHIDAATFLE MSMEG_2344|M.smegmatis_MC2_155 NALWFALRSPTFRLRDLMRLDAKAAAPLAAVSVPGIYDRLDHIDAETFLK Mflv_1844|M.gilvum_PYR-GCK NAMAFALRSPTFRVRDLIRLDARAAAPLAAVSVPGTYDELDDQDAESFLR Mvan_1580|M.vanbaalenii_PYR-1 NALAFALRSPTFRLRDLVRLDAKAAAPLAAVSVPETYDLLDGRDAETFLR TH_1483|M.thermoresistible__bu NAMAFALRSPTFRLRDLIRLNARAAAPLAAVELPGIYRHLDDTDAESFLR MMAR_4806|M.marinum_M RLREWLTRLYRIEFAGFIGSNFDSPLSLLTPQLARLAAAGGFRNWDSMVK MAB_2659|M.abscessus_ATCC_1997 DLEDLGR----------ITIEMGKLLETINVDAAWKSPNADQLDSISFGE : . . . : :: . MAV_3890|M.avium_104 -DIRFPEAARHLAFEVFSRSFFADPAKLSAAELATMFHIYFLGSAEGLIF MSMEG_2344|M.smegmatis_MC2_155 -DINFPPAARHLAFEVFSRSFFADPSNLSAAELATMFHIYFLGSSEGLVF Mflv_1844|M.gilvum_PYR-GCK -DINFPDAARHLAFEVFSRSFFTRPAALSAAELATMFHIYFLGSSEGLVF Mvan_1580|M.vanbaalenii_PYR-1 -DINFPEAARHLAFEVFARSFFARPETLSAGELVTMFHIYFLGSSEGLIF TH_1483|M.thermoresistible__bu -AINFPPAARHLAFEVFSRSFFAQPSQLSAAELATMFHIYFLGSSEGLVF MMAR_4806|M.marinum_M RHITDPRLRRVFTFQSLYAGVAP------QDALAAYAVIAYMDTISGVFF MAB_2659|M.abscessus_ATCC_1997 WLSQQQAVTSTNALMYIVTRVQWGCSPLDVSLLHVLRYVQAVGGLDHMLA :: : . * . : :. . :. MAV_3890|M.avium_104 DVP---SANYDSALWQPLRSYLEQRHVRFRLGTSVGSID----AANRFAV MSMEG_2344|M.smegmatis_MC2_155 DVP---TSNYDTALWEPLRRYLHEHGVRFHLGASVTRIDPVTTSPDAFAV Mflv_1844|M.gilvum_PYR-GCK DVA---TSNFDVALWNPLASYLERLGAHVHTGTAVDSVTATS--QNSFIV Mvan_1580|M.vanbaalenii_PYR-1 DVA---NANFDVALWNPLRRYLEGRGVVFHTGAEVDSVTVA----DEVTV TH_1483|M.thermoresistible__bu DVV---NANFDVALWNPLRDQLESRGVRFHTGVGVRAVDAG----ARFRV MMAR_4806|M.marinum_M PRG---GVR---ALPDALAAAAACAGVQFHYGSQVSELERDD--ARITAV MAB_2659|M.abscessus_ATCC_1997 VEHGQQEYRVTETTQEIAKRLAAQIGDQIVLNTRVRQISQDD---NGVTV . : : . . * : * MAV_3890|M.avium_104 HTDTDEELEVDAVVLATDVAGLQRIVAASRGLANGEWRDRIAGLRTAPPF MSMEG_2344|M.smegmatis_MC2_155 HTDSGERLDADAVVLAADIAGLQRIVASSPGLGDDRWRARVQGLRTAPPF Mflv_1844|M.gilvum_PYR-GCK TDGAGDENEVDGVVLATDVSALQSIVSSSESLGDPEWREKIHRMGTALPF Mvan_1580|M.vanbaalenii_PYR-1 TGSRAQVWSADAAVLATDPGSLRRVVAASPGLGDPSWRERVAAIGTAPPF TH_1483|M.thermoresistible__bu SCDSGDELTADGVVLATDVTGLQRIVAASPGLGDAGWRDRIAGLHTAPPF MMAR_4806|M.marinum_M RTDRGERIACDAVVLTTELPTTYRLLGRTP--------RRLRRLRAAPSA MAB_2659|M.abscessus_ATCC_1997 STDSG--VINAKYAIVTAAPEHRAYIEYQPALP-----AKIEGLTTSFPM . .:.: : :: : :: . MAV_3890|M.avium_104 AVHRFWLDRPVSPRRPAFLGTA--GHKPLDNISVLDRYEREARAWAGAHH MSMEG_2344|M.smegmatis_MC2_155 AVHRLWLDRPVTADRPAFMGTA--GHKPLDNISVLERYERQSAQWARDNG Mflv_1844|M.gilvum_PYR-GCK VVQRLWLDRPVRGDRPAFLGTG--GLPPLDNISVLERYEHEARDWCARTG Mvan_1580|M.vanbaalenii_PYR-1 VVLRLWLDRPVRHDRAAFVGTG--GRDPLDNISVLERYEREAAQWCSRTG TH_1483|M.thermoresistible__bu VVHRLWLDRPVAPDRPPFLGTG--GWSPLDNVSVLETYEHQARDWARCTG MMAR_4806|M.marinum_M VVVHAGCRSASTASEPAAHHTILFGQAWEQTFTDIIRDGRLMRDPSLLVT MAB_2659|M.abscessus_ATCC_1997 GALS---KAFVAYDKPFWRAEGLSGEALTDTAPVFITFDVSPSDDGPGIL . .. * :. . : MAV_3890|M.avium_104 GSVVELHSYALDSAPSGA--AALRELRRIYPETAAAQIVHETLLHRSDCP MSMEG_2344|M.smegmatis_MC2_155 GSAVELHAYALDTAESGP--GALAQLHRLYPETATAEPVFERVLVRDDCP Mflv_1844|M.gilvum_PYR-GCK GSVVELHAYSVDQDSPELRRALISRLHDLYPETVDATIVGEKTLCRNDCP Mvan_1580|M.vanbaalenii_PYR-1 GSVVELHAYSVRDEDADVRDRLIARMHELYPETATASIVAERLLRRDDCP TH_1483|M.thermoresistible__bu GSVVELHSYAVTEPTDGLRDALLDRLHALYPETADAGIVAERVLCRQDCP MMAR_4806|M.marinum_M RPTAGDPALAPPGRDLLYLLAPAPNLTAGRVDWGSAGGSYAQSMIDTVAS MAB_2659|M.abscessus_ATCC_1997 MVFCTARVYDGFGPEVRR-KLVLKQLVDLYGEQANTPIDYIDHCWG-TEP .: : : . MAV_3890|M.avium_104 LFAPGGYPHRPTVVTPTPGLLLASDTVRIDLPVALMERAATTG-WSAAN- MSMEG_2344|M.smegmatis_MC2_155 LFAPGSHADRPGVVTGVPGLVLAGDGIRLDLPAALMERAATTG-WAAAN- Mflv_1844|M.gilvum_PYR-GCK RLAPGDFAQRPTVRTPHPGLALAGDGIRIDLPVALMERAATTG-IAAAN- Mvan_1580|M.vanbaalenii_PYR-1 RFAPGDFADRPTVSTPDPRLKLAGDGIRIDLPVALMERAATTG-WTAAN- TH_1483|M.thermoresistible__bu RFAPGDHAGRPGVAGPHPALALAGDGIRIDLPVALMERAATTG-WSAAN- MMAR_4806|M.marinum_M RLLP-DLRDSVELLDVVTPLDWARQGMAAGTPFALAHTFGQTGPFRPANT MAB_2659|M.abscessus_ATCC_1997 FAAGGPHPAAPPFASVN-----YGEALREPHGRIHWAGTETAGEWVGTMN . : : :* : MAV_3890|M.avium_104 -------HLLKRWGLAGHPLVTVPTEGRSRLLRWLANREGATRS------ MSMEG_2344|M.smegmatis_MC2_155 -------VLLNRWGVAGHALRSVPTAGRFAPLRWLATREERRAS------ Mflv_1844|M.gilvum_PYR-GCK -------SLLAHFGVTGHDMYTVPVRGRSPVLRHLANRVERRVLR----- Mvan_1580|M.vanbaalenii_PYR-1 -------ELLTGFGLAGHTLHTVPNRGRSAVLRRLATSAGG--VR----- TH_1483|M.thermoresistible__bu -------RLLTHFGLAGHPLYTVPTRGRSAALRRLARREVR-QVR----- MMAR_4806|M.marinum_M VRGIDNAVLAGSSTVPGVGVPTTLISGRLAADRITGNTTRSIRHLDLKAQ MAB_2659|M.abscessus_ATCC_1997 ----------------GAILMGLHTADQIAQQLGVTGEVSK--------- * : .: MAV_3890|M.avium_104 -- MSMEG_2344|M.smegmatis_MC2_155 -- Mflv_1844|M.gilvum_PYR-GCK -- Mvan_1580|M.vanbaalenii_PYR-1 -- TH_1483|M.thermoresistible__bu -- MMAR_4806|M.marinum_M LS MAB_2659|M.abscessus_ATCC_1997 --