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VVVVGGGIAGLAAATGLAERGVAVEVIEKHGYLGGRVGGWSDTLADGTPVAMNRGFHAFFRQYYNLRALL RRSDPGLSALTPVEDYPLIDGAGRRDTFRGLPQTPPLNALAFALRSPTFRLRDLVRLDAKAAAPLAAVSV PETYDLLDGRDAETFLRDINFPEAARHLAFEVFARSFFARPETLSAGELVTMFHIYFLGSSEGLIFDVAN ANFDVALWNPLRRYLEGRGVVFHTGAEVDSVTVADEVTVTGSRAQVWSADAAVLATDPGSLRRVVAASPG LGDPSWRERVAAIGTAPPFVVLRLWLDRPVRHDRAAFVGTGGRDPLDNISVLERYEREAAQWCSRTGGSV VELHAYSVRDEDADVRDRLIARMHELYPETATASIVAERLLRRDDCPRFAPGDFADRPTVSTPDPRLKLA GDGIRIDLPVALMERAATTGWTAANELLTGFGLAGHTLHTVPNRGRSAVLRRLATSAGGVR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1580 | - | - | 100% (481) | amine oxidase |
| M. vanbaalenii PYR-1 | Mvan_4388 | - | 2e-05 | 52.00% (50) | amine oxidase |
| M. vanbaalenii PYR-1 | Mvan_1578 | - | 8e-05 | 57.89% (38) | phytoene dehydrogenase-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1844 | - | 0.0 | 70.89% (474) | amine oxidase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4806 | crtI | 4e-05 | 55.26% (38) | phytoene dehydrogenase CrtI |
| M. avium 104 | MAV_3890 | - | 1e-174 | 65.90% (481) | dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2344 | - | 1e-179 | 68.89% (479) | dehydrogenase |
| M. thermoresistible (build 8) | TH_1483 | - | 0.0 | 70.80% (476) | dehydrogenase |
| M. ulcerans Agy99 | MUL_0254 | - | 4e-05 | 48.15% (54) | oxidoreductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1580|M.vanbaalenii_PYR-1 ------------------------------MVVVGGGIAGLAAATGLAER
Mflv_1844|M.gilvum_PYR-GCK ----MNDPRRVLHPAAAALPSASALGAQPKAAVIGGGIAGLAAATSLAER
TH_1483|M.thermoresistible__bu ----LTDPRRVHHHAPPGLPDARGLARRPHVVVVGAGIAGLAAATGLAER
MAV_3890|M.avium_104 MTAGATDRRRRILPAPTGLPDAGALPSRPRVAVVGGGIAGLTAATGLAER
MSMEG_2344|M.smegmatis_MC2_155 --------MQRTHTAPRGLPHAGELPRRPRVVVVGAGIAGLAAATGMAER
MMAR_4806|M.marinum_M --------------------MRTIEGTADHVVVIGAGLAGLATALHLAGR
MUL_0254|M.ulcerans_Agy99 -------------------------MKEFDVVVVGGGHNGLVAAAYLARA
.*:*.* **.:* :*
Mvan_1580|M.vanbaalenii_PYR-1 GVAVEVIEKHGYLGGRVG-----GWSDTLADGTP--VAMNRGFHAFFRQY
Mflv_1844|M.gilvum_PYR-GCK GVAVRLYERQSYLGGRVG-----GWQDTLDDGTT--VAMNRGFHAFFRQY
TH_1483|M.thermoresistible__bu GVTVDVVEQAGYLGGRVG-----GWTEDIGPDVPGGAAMNRGFHAFFRQY
MAV_3890|M.avium_104 GVAVEVIEREHYLGGRVG-----GWTEHHDGTDL---AMNRGFHAFFRQY
MSMEG_2344|M.smegmatis_MC2_155 GVEVTVIERENYLGGRVG-----GWSEQHDGAEY---AMNRGFHAFFRQY
MMAR_4806|M.marinum_M GRSVTVVEREAWPGGRAGRLDIDGYRIDTGPTVLTMPDLIDEVFAAVGET
MUL_0254|M.ulcerans_Agy99 GLRVRVLERLGYVGGAAVS---IQAFDGVEVRLSRYSYLVSLLPPQIIKD
* * : *: : ** . : . . . :
Mvan_1580|M.vanbaalenii_PYR-1 YNLRALLRRSDPGLSALTPVEDY---PLIDGAGRR-----DTFRGLPQTP
Mflv_1844|M.gilvum_PYR-GCK YNLRGILSRIDPSLSMLSPLTDY---PLVDALGRR-----DTFRGLPRTP
TH_1483|M.thermoresistible__bu YNLRTLLRRIDPGLGMLTPVDDY---PLVDAHGRR-----DTFRGLPKTP
MAV_3890|M.avium_104 YNLRALLARLDPRLRMLVPVNDY---PLIDAAGRR-----DSFRGLPRTP
MSMEG_2344|M.smegmatis_MC2_155 YNLRALLARVDPQLRMLTPVEDY---PLIDGEGRR-----ESFRRLPHTP
MMAR_4806|M.marinum_M ISDRLELLPVDPAYTAMFADGSS---IDVHCDADRMVAAIENFAGPEQAT
MUL_0254|M.ulcerans_Agy99 LGAPVRLARRQFSSYTPQPDTHGRSGLLIGTAGDDTFAAVGAAGDEPGFA
. * : . : . .
Mvan_1580|M.vanbaalenii_PYR-1 -PLNALAFALRSPTFRLRDLVRLDAKAAAPLAAVSVPETYDLLDGRDAET
Mflv_1844|M.gilvum_PYR-GCK -PFNAMAFALRSPTFRVRDLIRLDARAAAPLAAVSVPGTYDELDDQDAES
TH_1483|M.thermoresistible__bu -PFNAMAFALRSPTFRLRDLIRLNARAAAPLAAVELPGIYRHLDDTDAES
MAV_3890|M.avium_104 -PLNAMAFAVRSPTFRLRDFARIDARAAAPLAAVSVPGTYRRLDHIDAAT
MSMEG_2344|M.smegmatis_MC2_155 -PWNALWFALRSPTFRLRDLMRLDAKAAAPLAAVSVPGIYDRLDHIDAET
MMAR_4806|M.marinum_M GYLRLREWLTRLYRIEFAGFIGSNFDSPLSLLTPQLARLAAAGGFRNWDS
MUL_0254|M.ulcerans_Agy99 AFYRRCRLVTERLWPTLLEPLRTRDQARRTVVDYGAPEALGAWHAMIEEP
. . . : .: . .
Mvan_1580|M.vanbaalenii_PYR-1 FLR-DINFPEAARHLAFEVFARSFFARPETLSAGELVTMFHIYFLGSSEG
Mflv_1844|M.gilvum_PYR-GCK FLR-DINFPDAARHLAFEVFSRSFFTRPAALSAAELATMFHIYFLGSSEG
TH_1483|M.thermoresistible__bu FLR-AINFPPAARHLAFEVFSRSFFAQPSQLSAAELATMFHIYFLGSSEG
MAV_3890|M.avium_104 FLE-DIRFPEAARHLAFEVFSRSFFADPAKLSAAELATMFHIYFLGSAEG
MSMEG_2344|M.smegmatis_MC2_155 FLK-DINFPPAARHLAFEVFSRSFFADPSNLSAAELATMFHIYFLGSSEG
MMAR_4806|M.marinum_M MVKRHITDPRLRRVFTFQSLYAGVAP------QDALAAYAVIAYMDTISG
MUL_0254|M.ulcerans_Agy99 IGR-AITAAVHDDLVRGVIATDALIGTFAGLDEPSLTQNICFLYHLLGGG
: . * . . .. *. : : *
Mvan_1580|M.vanbaalenii_PYR-1 LIFDVANANFDVALWNPLRRYLEGRGVVFHTGAEVDSVTVA----DEVTV
Mflv_1844|M.gilvum_PYR-GCK LVFDVATSNFDVALWNPLASYLERLGAHVHTGTAVDSVTATS--QNSFIV
TH_1483|M.thermoresistible__bu LVFDVVNANFDVALWNPLRDQLESRGVRFHTGVGVRAVDAG----ARFRV
MAV_3890|M.avium_104 LIFDVPSANYDSALWQPLRSYLEQRHVRFRLGTSVGSID----AANRFAV
MSMEG_2344|M.smegmatis_MC2_155 LVFDVPTSNYDTALWEPLRRYLHEHGVRFHLGASVTRIDPVTTSPDAFAV
MMAR_4806|M.marinum_M VFFPRGGVR---ALPDALAAAAACAGVQFHYGSQVSELERDD--ARITAV
MUL_0254|M.ulcerans_Agy99 TGDWDVPIGGMGSVTAGLAAAATGYGAEIVTGAEAVAVTPNG---DVRYR
:: * . . * . :
Mvan_1580|M.vanbaalenii_PYR-1 TGSRAQVWSADAAVLATDPGSLRRVVAASPGLGDPSWRERVAAIGTAPPF
Mflv_1844|M.gilvum_PYR-GCK TDGAGDENEVDGVVLATDVSALQSIVSSSESLGDPEWREKIHRMGTALPF
TH_1483|M.thermoresistible__bu SCDSGDELTADGVVLATDVTGLQRIVAASPGLGDAGWRDRIAGLHTAPPF
MAV_3890|M.avium_104 HTDTDEELEVDAVVLATDVAGLQRIVAASRGLANGEWRDRIAGLRTAPPF
MSMEG_2344|M.smegmatis_MC2_155 HTDSGERLDADAVVLAADIAGLQRIVASSPGLGDDRWRARVQGLRTAPPF
MMAR_4806|M.marinum_M RTDRGERIACDAVVLTTELPTTYRLLGRTP--------RRLRRLRAAPSA
MUL_0254|M.ulcerans_Agy99 AGDDEHLVRGRFVLAGVTPAVLAKLLGDTEP-------SFAPGAQVKVNM
. . .: . ::. : .
Mvan_1580|M.vanbaalenii_PYR-1 VVLRL-WLDRPVRHDRAAFVGTG--GRDPLDNISVLERYER---EAAQWC
Mflv_1844|M.gilvum_PYR-GCK VVQRL-WLDRPVRGDRPAFLGTG--GLPPLDNISVLERYEH---EARDWC
TH_1483|M.thermoresistible__bu VVHRL-WLDRPVAPDRPPFLGTG--GWSPLDNVSVLETYEH---QARDWA
MAV_3890|M.avium_104 AVHRF-WLDRPVSPRRPAFLGTA--GHKPLDNISVLDRYER---EARAWA
MSMEG_2344|M.smegmatis_MC2_155 AVHRL-WLDRPVTADRPAFMGTA--GHKPLDNISVLERYER---QSAQWA
MMAR_4806|M.marinum_M VVVHA-GCRSASTASEPAAHHTILFGQAWEQTFTDIIRDGR---LMRDPS
MUL_0254|M.ulcerans_Agy99 VLRRLPRLRDAVVTPEQAFAGTFHANETWTQLEAAHQRAAAGHLPDPLPC
.: : . . . * . : : .
Mvan_1580|M.vanbaalenii_PYR-1 SRTGGSVVELHAYSVRDEDADVRDRLIARMHELYPETATASIVAERLLRR
Mflv_1844|M.gilvum_PYR-GCK ARTGGSVVELHAYSVDQDSPELRRALISRLHDLYPETVDATIVGEKTLCR
TH_1483|M.thermoresistible__bu RCTGGSVVELHSYAVTEPTDGLRDALLDRLHALYPETADAGIVAERVLCR
MAV_3890|M.avium_104 GAHHGSVVELHSYALDSAPSGA--AALRELRRIYPETAAAQIVHETLLHR
MSMEG_2344|M.smegmatis_MC2_155 RDNGGSAVELHAYALDTAESGP--GALAQLHRLYPETATAEPVFERVLVR
MMAR_4806|M.marinum_M LLVTRPTAGDPALAPPGRDLLYLLAPAPNLTAGRVDWGSAGGSYAQSMID
MUL_0254|M.ulcerans_Agy99 EAYCHSLSDPSILSPALRDVGAQTMTVFGLHTPHSVFGNADPDVLRDQLT
. : : *
Mvan_1580|M.vanbaalenii_PYR-1 DDCPRFAPGDFADRPT--VSTPDPRLKLAGDGIRIDLPVALMERAATTG-
Mflv_1844|M.gilvum_PYR-GCK NDCPRLAPGDFAQRPT--VRTPHPGLALAGDGIRIDLPVALMERAATTG-
TH_1483|M.thermoresistible__bu QDCPRFAPGDHAGRPG--VAGPHPALALAGDGIRIDLPVALMERAATTG-
MAV_3890|M.avium_104 SDCPLFAPGGYPHRPT--VVTPTPGLLLASDTVRIDLPVALMERAATTG-
MSMEG_2344|M.smegmatis_MC2_155 DDCPLFAPGSHADRPG--VVTGVPGLVLAGDGIRLDLPAALMERAATTG-
MMAR_4806|M.marinum_M TVASRLLP-DLRDSVE--LLDVVTPLDWARQGMAAGTPFALAHTFGQTGP
MUL_0254|M.ulcerans_Agy99 AAVLASLNSVLAEPIQDVLLTDADGRPCIETTTTADLQHTLHMTAGNIFH
: . :* .
Mvan_1580|M.vanbaalenii_PYR-1 ----WTAAN--------ELLTGFGLAGHTLHTVPNRG---RSAVLRRLAT
Mflv_1844|M.gilvum_PYR-GCK ----IAAAN--------SLLAHFGVTGHDMYTVPVRG---RSPVLRHLAN
TH_1483|M.thermoresistible__bu ----WSAAN--------RLLTHFGLAGHPLYTVPTRG---RSAALRRLAR
MAV_3890|M.avium_104 ----WSAAN--------HLLKRWGLAGHPLVTVPTEG---RSRLLRWLAN
MSMEG_2344|M.smegmatis_MC2_155 ----WAAAN--------VLLNRWGVAGHALRSVPTAG---RFAPLRWLAT
MMAR_4806|M.marinum_M ----FRPANTVRGIDNAVLAGSSTVPGVGVPTTLISG---RLAADRITGN
MUL_0254|M.ulcerans_Agy99 GALSWPFAENDD--TLATPAQQWGVATNHDRIMLCGSGARRGGAVSGIGG
*: :. . * .
Mvan_1580|M.vanbaalenii_PYR-1 SAGG--VR-------
Mflv_1844|M.gilvum_PYR-GCK RVERRVLR-------
TH_1483|M.thermoresistible__bu REVR-QVR-------
MAV_3890|M.avium_104 REGATRS--------
MSMEG_2344|M.smegmatis_MC2_155 REERRAS--------
MMAR_4806|M.marinum_M TTRSIRHLDLKAQLS
MUL_0254|M.ulcerans_Agy99 HNAAMAVLAYLRQDR