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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_1288 | - | - | 100% (381) | two-component system sensor kinase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0868 | - | 5e-06 | 23.81% (231) | two component sensor kinase |
M. gilvum PYR-GCK | Mflv_3580 | - | 1e-140 | 71.15% (364) | putative signal transduction histidine kinase |
M. tuberculosis H37Rv | Rv0845 | - | 1e-05 | 24.76% (210) | two component sensor kinase |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_4520c | - | 2e-90 | 48.65% (370) | putative two-component system sensor kinase |
M. marinum M | MMAR_3958 | - | 1e-148 | 68.52% (378) | two-component sensor kinase |
M. avium 104 | MAV_4112 | - | 1e-142 | 66.23% (379) | hypothetical protein MAV_4112 |
M. smegmatis MC2 155 | MSMEG_3239 | - | 1e-144 | 72.09% (369) | two-component system sensor kinase |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_2835 | - | 1e-147 | 72.36% (369) | putative signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_3580|M.gilvum_PYR-GCK --------------------------------------MWRAAQVFRLLS Mvan_2835|M.vanbaalenii_PYR-1 ------------------------------MTPDPATPLWRAAQVFRLLS MSMEG_3239|M.smegmatis_MC2_155 ----------------------------MQREPDPVTPLWRAAQGFRLLS TH_1288|M.thermoresistible__bu ---------------------------MAAERVDPATPLWRAAQVFRLLS MMAR_3958|M.marinum_M ---------------------------MATRGPDPTAPLWRAAQLFRLLS MAV_4112|M.avium_104 -----------------------MLTTMANHGPDPTTPLWRAAQVFRLLS MAB_4520c|M.abscessus_ATCC_199 ------------------MGSKNGTVPRWMSGSDPTASLWRAAQVFRLAS Mb0868|M.bovis_AF2122/97 MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGV Rv0845|M.tuberculosis_H37Rv MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGV :* *. :*: Mflv_3580|M.gilvum_PYR-GCK CVYAFG-FQLAVN-ADLESPVAGWVLFGALLAWSLACAVAYLQGFGRRLS Mvan_2835|M.vanbaalenii_PYR-1 CIYAFG-FQLAVN-PDLEHPVGGWVLFAVLIGWSAACATAYLQGFGRRPA MSMEG_3239|M.smegmatis_MC2_155 CLYALG-FHIAIT-DDLRRPVLGWVLFAGLIVWSAACATVYLTGSRRRGT TH_1288|M.thermoresistible__bu CLYAVG-FQIAVN-GDLRHPAAGWLMLAVLLAWSAACAVGYLNGFARRPG MMAR_3958|M.marinum_M CGYALG-FHIAIN-ANLQRPLLGWALFAVLIGWSAACAVAYLRGFGRRPA MAV_4112|M.avium_104 CLYATG-FQIAIN-PDLLRPVLGWVLFAGLIGWSAACALAYLRGFGRKPA MAB_4520c|M.abscessus_ATCC_199 FGYALLASQLASY-TNYERQGLSWALYAVMAMWTGFAAVALSRNWFRRWQ Mb0868|M.bovis_AF2122/97 VGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR Rv0845|M.tuberculosis_H37Rv VGLMVAAMVVGTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRR :. : : . *: * Mflv_3580|M.gilvum_PYR-GCK WVLAEVAVVIALVLSTEFLAS-DQWALDNQSWPTTLWATNATISAAILSG Mvan_2835|M.vanbaalenii_PYR-1 WVLAEIVVVVALMLSTEFVAS-DQWALDNQSWPTTLWATNATISAAILSG MSMEG_3239|M.smegmatis_MC2_155 WVIAELVVVVALMLSTELVAS-EQWIADNQSWPTTLWATNATISVALHFG TH_1288|M.thermoresistible__bu WVIAEIVVVIALMLATGLIAD-AAWVADNQSLPTTLWATNATISAAIQFG MMAR_3958|M.marinum_M WVITEIAVVVVLMLSTKMVAS-AQWALDNQTWPTTLWASNATISAALQFG MAV_4112|M.avium_104 WVLAELVVVVLLMWSNHLVAS-PHWAADNQTWPTTLWASNPTISAAIQFG MAB_4520c|M.abscessus_ATCC_199 LVLCDQAIVIALMLAGRLVVD-VQWYSGHQTLPTTLWVANAVVSMGLLRG Mb0868|M.bovis_AF2122/97 FRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLPVLVGLDVST Rv0845|M.tuberculosis_H37Rv FRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLPVLVGLDVST . : :: . * : ..: Mflv_3580|M.gilvum_PYR-GCK PVAGMLAGLAVVAAGAALKG--YVSIDLGRNATIVIELAVGLAVGMAAQT Mvan_2835|M.vanbaalenii_PYR-1 PVSGMLAGLVVVAASAALKG--YVSIDLGRNATVVIELAVGLAVGMAAQT MSMEG_3239|M.smegmatis_MC2_155 PIGGMSAGLAVMATVALLKG--HVSVNLGRNATIVIELAVGLAVGMAAQT TH_1288|M.thermoresistible__bu PVRGMLTGVAVMLAAAALKG--HISINLGRNATIVIELAVGLAVGMAAQT MMAR_3958|M.marinum_M PAGGMLTGIAVTAANEAVKG--YVNVNLGRSATIVIELAVGLAVGMAART MAV_4112|M.avium_104 PVGGMLTGLAVMTANFAVKN--YFALNLGHNATVIIELAIGMAIGMAAQT MAB_4520c|M.abscessus_ATCC_199 QLAGVISGFVLAAVSIAARG--LPVSALWLDATMPALVVVGLAIGAASTT Mb0868|M.bovis_AF2122/97 RRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMV Rv0845|M.tuberculosis_H37Rv RRAAVVLACTLVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMV .: . .: . : *: .: . * . Mflv_3580|M.gilvum_PYR-GCK ARRAHAELERATRLAASLEE------------RERLSRQVHDGAIQVLAL Mvan_2835|M.vanbaalenii_PYR-1 ARRAHAELERAARLSASLEE------------RERLSRQVHDGAIQVLAL MSMEG_3239|M.smegmatis_MC2_155 ARRAHAELERAVRLSAALEE------------RERLSRRVHDGAIQVLAL TH_1288|M.thermoresistible__bu ARRAHAELRRAARLAAVTEE------------RERLSRQVHDGAIQVLAL MMAR_3958|M.marinum_M ARRAHADLQRAAQLSAALQE------------RERLSRQVHDGVIQVLAL MAV_4112|M.avium_104 ARRAHDELQRAARLTAAAQE------------RDRLARQVHDGAIQVLAL MAB_4520c|M.abscessus_ATCC_199 AKRTFHELRRAERAAAAAIE------------RERLSRQVHDGVLQVLSY Mb0868|M.bovis_AF2122/97 VRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAIHDGPLQDVLA Rv0845|M.tuberculosis_H37Rv VRIEERHTRSVAGLSALRAELLAQTMTASEVLQRRIAEAIHDGPLQDVLA .: . . . :* * : *::. :*** :* : Mflv_3580|M.gilvum_PYR-GCK VARRGREIGGDT---AQLAELAGEQERALRRLVSAADTPHR-AGATADLG Mvan_2835|M.vanbaalenii_PYR-1 VARRGREIGGDT---AQLAELAGEQERALRRLVSANDAEPR-KGAMSDIG MSMEG_3239|M.smegmatis_MC2_155 VARRGREIGGET---AKLAELAGEQERALRRLVSAADTDTM-AGPLTDVG TH_1288|M.thermoresistible__bu VARRGREIGGEV---TELAELAGEQERALRRLVSATESAPGGADHTVDVA MMAR_3958|M.marinum_M VSRRGHEIGGPT---SELAELASEQERALRRWIISTDTDRDGNTRSVDLC MAV_4112|M.avium_104 VAKKGHEIGGAT---TELADLASEQERALRRWLACTDIDRDADGDTVDLR MAB_4520c|M.abscessus_ATCC_199 VKRRGTEIGGPT---AELAAIAGEQEIALRELISGATQTTLADDELVDLR Mb0868|M.bovis_AF2122/97 ARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG Rv0845|M.tuberculosis_H37Rv ARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG . :. *:.. . .:. . : * .. .: Mflv_3580|M.gilvum_PYR-GCK AMLRSRASDRVSVS----VPAEPVLLDSAVATEFFAAVTNALDNAEAHAG Mvan_2835|M.vanbaalenii_PYR-1 AMLRRRATDRVSIS----VPADPVLLDATVADELLAAVTNALDNVEAHAG MSMEG_3239|M.smegmatis_MC2_155 ALLRTRASDRVSVS----VPAEPVLLDHPVARELFAAAENALDNVAAHAG TH_1288|M.thermoresistible__bu TLLRRRACDRVTMS----LPGTPVPMDADVAAELDAAVGNALDNVALHAG MMAR_3958|M.marinum_M ALLRRRASDRVSMS----LPGTPVTLTREVATELDAAVGNALDNVRLHAG MAV_4112|M.avium_104 TLLRRRESDRVSIS----LPGTPVRLGRWAATELDAAVGNALDNVVAHAG MAB_4520c|M.abscessus_ATCC_199 PLLRTQASTTVSVS----APGAPVLIGQHMASELAAVVRSALSNVALHAG Mb0868|M.bovis_AF2122/97 PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSG Rv0845|M.tuberculosis_H37Rv PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSG . :: . * . : . ... . *.*. *:* Mflv_3580|M.gilvum_PYR-GCK PHARVYVLLEDLGDSVTVSVRDDGVGIPEGRLEAAVGEGRVGVAKSIVGR Mvan_2835|M.vanbaalenii_PYR-1 PVARAYVLLEDLGATVTVTVRDDGVGIPEGRLDEAVTEGRVGVSKSIVGR MSMEG_3239|M.smegmatis_MC2_155 ADARAFVLLEDLGEEVTVSIRDDGVGIPEGRLAEAERQGRMGVAKSIVGR TH_1288|M.thermoresistible__bu PDARAFVLVEDLGDTVTVSIRDDGAGIAPGRLDEAVREGRMGIAKSIVGR MMAR_3958|M.marinum_M PSARAFVLLEDLGDSVTVSVRDDGVGIAPGRLDEAAGQGHLGISKSIVGR MAV_4112|M.avium_104 PGAHAFVLVEDLGDSVLVSVRDDGVGIAAGRVEEAARQGRLGISQSIVGR MAB_4520c|M.abscessus_ATCC_199 PQAHAYVLIEDLVDSVVVTVRDDGSGIADGRLDQAEREGRMGVSRSILGR Mb0868|M.bovis_AF2122/97 -ATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARV Rv0845|M.tuberculosis_H37Rv -ATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARV : . * : : : *** *:. . : :*::*:: Mflv_3580|M.gilvum_PYR-GCK MNWLGGRAELATGPGVGTEWELTVPR------- Mvan_2835|M.vanbaalenii_PYR-1 MDWLGGRAELSTGPGMGTEWELTVSR------- MSMEG_3239|M.smegmatis_MC2_155 MDWLGGTAVLTTGPDSGTEWELTVPRTRKGQ-- TH_1288|M.thermoresistible__bu MESLGGEAVLTTS-ERGTEWELTVPRKDGRHG- MMAR_3958|M.marinum_M LAALGGTAELSTDQGEGTEWELRVPRREGSS-- MAV_4112|M.avium_104 LASLGGTAELHSEPGAGTEWELCVPRREGRDDG MAB_4520c|M.abscessus_ATCC_199 VADLGGAVLLETGPGAGTEWEITVPKSQEVGA- Mb0868|M.bovis_AF2122/97 DAAGGVLVFLATPRGTHVCVELPLKR------- Rv0845|M.tuberculosis_H37Rv DAAGGVLVFLATPRGTHVCVELPLKR------- * . * : . *: : :