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M. thermoresistible (build 8) TH_0524 (-)

annotation: amidohydrolase family protein
coordinates: 1129916 - 1131058
length: 381

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0524--100% (381)amidohydrolase family protein
M. thermoresistible (build 8)TH_4618-4e-3427.87% (366) PUTATIVE amidohydrolase 2
M. thermoresistible (build 8)TH_0554-2e-1424.91% (269) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2489-0.090.79% (380) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4725-0.079.53% (381) metal-dependent hydrolase
M. avium 104MAV_0929-0.080.53% (380) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_4808-0.084.34% (364) amidohydrolase family protein
M. ulcerans Agy99MUL_4959-6e-1225.37% (268) hypothetical protein MUL_4959
M. vanbaalenii PYR-1Mvan_4165-0.091.84% (380) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2489|M.gilvum_PYR-GCK          ------MTVT-ANPRVPAAERIAVRCVDSDVHP-------------APRR
Mvan_4165|M.vanbaalenii_PYR-1       ------MTVT-ANPRVAATERIAVRCVDSDVHP-------------TPRR
TH_0524|M.thermoresistible__bu      ------MTVT-TNPRVPATERTAIRCVDSDVHP-------------TPRR
MSMEG_4808|M.smegmatis_MC2_155      -----------------------MRCVDSDVHP-------------MPRR
MMAR_4725|M.marinum_M               ------MTLTHMHERVPAAERIAVRCVDSDIHP-------------VPKR
MAV_0929|M.avium_104                ------MTLTHMQERVPAAERIAVRCVDSDVHP-------------VPKR
MUL_4959|M.ulcerans_Agy99           MKTELGFTFFDCGNHYYEAVDAFTRHIEREYKKRAIQWAQLDGRARLIIG
                                                            * :: : :                  

Mflv_2489|M.gilvum_PYR-GCK          GELTPYIPEPWRSKYFLTRKIGEQIYYDAPDYAHSFAMRVDAFPSDGEFA
Mvan_4165|M.vanbaalenii_PYR-1       GELLPYIPEPWRSKYFLTRKVGEQIYYDAPDYAHSYAMRVDTFPPDGEFA
TH_0524|M.thermoresistible__bu      GELLPYIPEPWRSKYFLTRKVGEQIYYDAPDYAHSYAMRVDAFPPDGEFA
MSMEG_4808|M.smegmatis_MC2_155      GELVEYIPEPWRSKYFLSHRVGEQIYYDAPDYAHAYAMRVDAFPPDGEFA
MMAR_4725|M.marinum_M               GEISPYIPEPWRSKFFLDHKVGELIYYDAPDYAHSFAMRVDTFPADGEFP
MAV_0929|M.avium_104                GEITPYIPERWR-KFFFEHRVGELIYYDAPDYAHAFAMRTDTFPPDGEFP
MUL_4959|M.ulcerans_Agy99           GRVNRFIPNPTFDPVGKPGALDEYFRGRNPRGADLNALFGDLEPIRPEYR
                                    *.:  :**:           :.* :    *  *.  *:  *  *   *: 

Mflv_2489|M.gilvum_PYR-GCK          CSDPDLAFK-QLIMEAGADIAILEPAAYPARIP--EAQHAMSCALNDWQA
Mvan_4165|M.vanbaalenii_PYR-1       CSDPDLAFK-QLIMEAGADIAVLEPAAYPARIP--EAQHAMSVALNDWQA
TH_0524|M.thermoresistible__bu      CSDPDLAFR-QLIMEAGADIAILEPAAYPARTP--ETQHAMAVALNDWQA
MSMEG_4808|M.smegmatis_MC2_155      CSDPDMALR-QLIMEAGSDIAILEPTHSEHRLG--EATAAYCTAVNEWLA
MMAR_4725|M.marinum_M               GSDPDMAFR-QLIMEAGSDIAILEPGGRTPRLP--EAHQAYSTALNRWQA
MAV_0929|M.avium_104                GSDPDMAFR-QLIMEAGSDIAILEPAGRTPRIG--EAHQAYCSALNDWQA
MUL_4959|M.ulcerans_Agy99           DRDARLAAMDEQGMQGCIMLPTLGVGMEQALLPDLEATAATFRAFNRWMQ
                                      *. :*   :  *:.   :. *            *:  *   *.* *  

Mflv_2489|M.gilvum_PYR-GCK          NHWLDSHNNWHERWRGSICLAIEEPEHSVAEIERWVGHPYMAQILIKAEP
Mvan_4165|M.vanbaalenii_PYR-1       NHWLDSHNNWHERWRGSICLAIEEPEKSVEEIERWAGHPYMAQILIKAEP
TH_0524|M.thermoresistible__bu      NHWLDSHNNWHQRWRGSICLAIEAPEDSVREIERWAGHPYMAQILIKAEP
MSMEG_4808|M.smegmatis_MC2_155      DNWLDSHNNWHQRWRGSICAAIEEPQSAVAEIEKWAGHPYMAQILIKAEP
MMAR_4725|M.marinum_M               NHWLDSHNNWHQRWRGSICAAVEDPEGAAREIEEWAGHPYMAQVLIKAEP
MAV_0929|M.avium_104                NHWLDSRNNWHERWRGSICAAIEDPEGAVEQIEKWAGHPYMAQILIKAEP
MUL_4959|M.ulcerans_Agy99           EDWG---FAYQERIFAAPYITLCIPDNAVRELEWALRHDARFIVMVPGPV
                                    :.*      :::*  .:   ::  *: :. ::*    *     ::: .  

Mflv_2489|M.gilvum_PYR-GCK          R-----PSWGNPKYDPIWAAAAKHDIPVSCHLSRSHYDELPMPPVGLPSY
Mvan_4165|M.vanbaalenii_PYR-1       R-----PSWGNPKYDPIWAAATKHDITVSCHLSRSHYDELPMPPVGLPSY
TH_0524|M.thermoresistible__bu      R-----PSWGDPKYDPIWAAAAKHDITVSCHLSRSHHEELPMPPVGMPSY
MSMEG_4808|M.smegmatis_MC2_155      R-----PSWGDPKYDPIWAAATKHDIVVSCHLSRGEFETLPLPPVGLPSY
MMAR_4725|M.marinum_M               R-----PCWGHPMYNPIWAAATKHDITVSCHLSRSNFEMLPTPPVGYPSY
MAV_0929|M.avium_104                R-----PSWGHPKYDPIWAAATKHDIVVSCHLSRSNYEMLPTPPVGFPSY
MUL_4959|M.ulcerans_Agy99           TTEVGMRAPGDPLFDPFWQLANDSGITVCYHSGETYYSKF-MPAWGEADY
                                           . *.* ::*:*  * . .* *. * ..  .. :  *. * ..*

Mflv_2489|M.gilvum_PYR-GCK          NHDFMVTY---SLLAAN----QVMSLIFDGTFDRHPNLRIVFVEHAFTWI
Mvan_4165|M.vanbaalenii_PYR-1       NHDFMVTY---SLLAAN----QVMSLIFDGTFDRHPNLRIVFVEHAFTWI
TH_0524|M.thermoresistible__bu      NHDFMVTY---SLLAVN----QVMSLIFDGVFDRFPNLRVVFVEHAFTWI
MSMEG_4808|M.smegmatis_MC2_155      NHDFMVTY---SLLAAN----QVMSLIFDGVFDRFPTLRIVFVEHAFTWI
MMAR_4725|M.marinum_M               NHDFMVTY---SLLAAN----QVMSLIFDGVFDRFPTLRIVLVEHAFTWI
MAV_0929|M.avium_104                NHDFMVTY---SLLAAN----QVMSLIFDGVFDRFPTLRIVFVEHAFTWI
MUL_4959|M.ulcerans_Agy99           MMSFQALLGFRSLFSGDPLQDTFANHLHKGLFHRFPNLRMACIESGSAWV
                                      .* .     **:: :     . . :..* *.*.*.**:. :* . :*:

Mflv_2489|M.gilvum_PYR-GCK          LPLMWRMDALYEARKSWVEIKRKPSEYVKDHIKFTTQPLDYPEDKTELSR
Mvan_4165|M.vanbaalenii_PYR-1       LPLMWRMDALYEARKSWVDIKRRPSEYVKDHIKFTTQPLDYPEDKTELSR
TH_0524|M.thermoresistible__bu      LPLMWRMDAIYEARKSWLEIKRKPSEYVKDHIKFTTQPLDYPEDKTELTR
MSMEG_4808|M.smegmatis_MC2_155      LPLMWRMDAIYERRKSWLNIKRKPSEYVKDHIKFTTQPLDYPEDKTELSR
MMAR_4725|M.marinum_M               LPLMWRMDALYDARKSRMDIKRKPSEYVKEHIKFTTQPLDYPEDKTELTR
MAV_0929|M.avium_104                LPLMWRMDAIYEARKSRVQIKRKPSEYVKDHIKFTTQPLDYPEDKTELTR
MUL_4959|M.ulcerans_Agy99           FHLFEKLAKSYG--QIPFIYQEDPRETFKRHVWVS------PFYEDELAD
                                    : *: ::   *   :  .  :. * * .* *: .:      *  : **: 

Mflv_2489|M.gilvum_PYR-GCK          AFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFKNGIETY
Mvan_4165|M.vanbaalenii_PYR-1       AFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIETY
TH_0524|M.thermoresistible__bu      ALEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIETY
MSMEG_4808|M.smegmatis_MC2_155      AFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAIMFRNGLKTY
MMAR_4725|M.marinum_M               AIEWMEGDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIATY
MAV_0929|M.avium_104                ALEWMECDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIATY
MUL_4959|M.ulcerans_Agy99           LLKLLGADRIIMG-SDYPHVEGLAEPASYIKDLQNFDYAPDQCRAVMRDN
                                     :: :  ::*::  *****   : :*   :*.* :    .   :  :   

Mflv_2489|M.gilvum_PYR-GCK          KLPDTVPALEGQVRVF
Mvan_4165|M.vanbaalenii_PYR-1       KLPDTVPALEGQVRVF
TH_0524|M.thermoresistible__bu      KLPETVPALEGQTRVF
MSMEG_4808|M.smegmatis_MC2_155      KLPDTVPVLEGQVRVF
MMAR_4725|M.marinum_M               HLPDTVPVLEGQTRVF
MAV_0929|M.avium_104                HLPETVPVLEGQVRVL
MUL_4959|M.ulcerans_Agy99           GLELALRRPV------
                                     *  ::