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M. vanbaalenii PYR-1 Mvan_4165 (-)

annotation: amidohydrolase 2
coordinates: 4476463 - 4477605
length: 380

MTVTANPRVAATERIAVRCVDSDVHPTPRRGELLPYIPEPWRSKYFLTRKVGEQIYYDAPDYAHSYAMRV
DTFPPDGEFACSDPDLAFKQLIMEAGADIAVLEPAAYPARIPEAQHAMSVALNDWQANHWLDSHNNWHER
WRGSICLAIEEPEKSVEEIERWAGHPYMAQILIKAEPRPSWGNPKYDPIWAAATKHDITVSCHLSRSHYD
ELPMPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFTWILPLMWRMDALYEARK
SWVDIKRRPSEYVKDHIKFTTQPLDYPEDKTELSRAFEWMECEKILLFSSDYPHWTFDDPRWLVKHLPEH
AREAVMFRNGIETYKLPDTVPALEGQVRVF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_4165--100% (380)amidohydrolase 2
M. vanbaalenii PYR-1Mvan_4164-4e-3629.03% (372) amidohydrolase 2
M. vanbaalenii PYR-1Mvan_2602-1e-1223.94% (284) amidohydrolase 2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2489-0.095.26% (380) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4725-0.079.53% (381) metal-dependent hydrolase
M. avium 104MAV_0929-0.081.05% (380) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_4808-0.084.34% (364) amidohydrolase family protein
M. thermoresistible (build 8)TH_0524-0.091.84% (380) amidohydrolase family protein
M. ulcerans Agy99MUL_3878-9e-1326.38% (235) metal-dependent hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_4165|M.vanbaalenii_PYR-1       -----------------MTVT-ANPRVAATERIAVRCVDSDVHPTPRRGE
Mflv_2489|M.gilvum_PYR-GCK          -----------------MTVT-ANPRVPAAERIAVRCVDSDVHPAPRRGE
TH_0524|M.thermoresistible__bu      -----------------MTVT-TNPRVPATERTAIRCVDSDVHPTPRRGE
MSMEG_4808|M.smegmatis_MC2_155      ----------------------------------MRCVDSDVHPMPRRGE
MMAR_4725|M.marinum_M               -----------------MTLTHMHERVPAAERIAVRCVDSDIHPVPKRGE
MAV_0929|M.avium_104                -----------------MTLTHMQERVPAAERIAVRCVDSDVHPVPKRGE
MUL_3878|M.ulcerans_Agy99           MDSLGYKAIDVDNHYYEPLDAFTRHLDKKFRRRGVQLVTDGRHTQVIIGD
                                                                      :: * .. *.    *:

Mvan_4165|M.vanbaalenii_PYR-1       -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDTFPPDGEFA
Mflv_2489|M.gilvum_PYR-GCK          -LTPYIPEPWRSKYFLTRKIGEQIYYDAPD-YAHSFAMRVDAFPSDGEFA
TH_0524|M.thermoresistible__bu      -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDAFPPDGEFA
MSMEG_4808|M.smegmatis_MC2_155      -LVEYIPEPWRSKYFLSHRVGEQIYYDAPD-YAHAYAMRVDAFPPDGEFA
MMAR_4725|M.marinum_M               -ISPYIPEPWRSKFFLDHKVGELIYYDAPD-YAHSFAMRVDTFPADGEFP
MAV_0929|M.avium_104                -ITPYIPERWR-KFFFEHRVGELIYYDAPD-YAHAFAMRTDTFPPDGEFP
MUL_3878|M.ulcerans_Agy99           RVNRFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPASLMKVEKLELRPEYR
                                     :  :**:      :.   :.  :  : **    :  *:.: :    *: 

Mvan_4165|M.vanbaalenii_PYR-1       CSDPDLAFKQLIMEAGADIAVLEPAAYPARIPEAQHAMSVALNDWQANHW
Mflv_2489|M.gilvum_PYR-GCK          CSDPDLAFKQLIMEAGADIAILEPAAYPARIPEAQHAMSCALNDWQANHW
TH_0524|M.thermoresistible__bu      CSDPDLAFRQLIMEAGADIAILEPAAYPARTPETQHAMAVALNDWQANHW
MSMEG_4808|M.smegmatis_MC2_155      CSDPDMALRQLIMEAGSDIAILEPTHSEHRLGEATAAYCTAVNEWLADNW
MMAR_4725|M.marinum_M               GSDPDMAFRQLIMEAGSDIAILEPGGRTPRLPEAHQAYSTALNRWQANHW
MAV_0929|M.avium_104                GSDPDMAFRQLIMEAGSDIAILEPAGRTPRIGEAHQAYCSALNDWQANHW
MUL_3878|M.ulcerans_Agy99           --NRDARVVVVESQGIETIFMFPTFGCGVEEALKADIEATAASLHAFNLW
                                      : *  .  :  :.   * :: .     .        . * .    : *

Mvan_4165|M.vanbaalenii_PYR-1       LDSHNNWH---ERWRGSICLAIEEPEKSVEEIERWAGHPYMAQILIKAEP
Mflv_2489|M.gilvum_PYR-GCK          LDSHNNWH---ERWRGSICLAIEEPEHSVAEIERWVGHPYMAQILIKAEP
TH_0524|M.thermoresistible__bu      LDSHNNWH---QRWRGSICLAIEAPEDSVREIERWAGHPYMAQILIKAEP
MSMEG_4808|M.smegmatis_MC2_155      LDSHNNWH---QRWRGSICAAIEEPQSAVAEIEKWAGHPYMAQILIKAEP
MMAR_4725|M.marinum_M               LDSHNNWH---QRWRGSICAAVEDPEGAAREIEEWAGHPYMAQVLIKAEP
MAV_0929|M.avium_104                LDSRNNWH---ERWRGSICAAIEDPEGAVEQIEKWAGHPYMAQILIKAEP
MUL_3878|M.ulcerans_Agy99           LDEDWGFDRPDHRIIAAPMISLADPEKALQEVEFVLERG-ARMVHVRPAP
                                    **.  .:.   .*  .:   ::  *: :  ::*    :     : ::. *

Mvan_4165|M.vanbaalenii_PYR-1       RP------SWGNPKYDPIWAAATKHDITVSCHLSRSHYDELP--------
Mflv_2489|M.gilvum_PYR-GCK          RP------SWGNPKYDPIWAAAAKHDIPVSCHLSRSHYDELP--------
TH_0524|M.thermoresistible__bu      RP------SWGDPKYDPIWAAAAKHDITVSCHLSRSHHEELP--------
MSMEG_4808|M.smegmatis_MC2_155      RP------SWGDPKYDPIWAAATKHDIVVSCHLSRGEFETLP--------
MMAR_4725|M.marinum_M               RP------CWGHPMYNPIWAAATKHDITVSCHLSRSNFEMLP--------
MAV_0929|M.avium_104                RP------SWGHPKYDPIWAAATKHDIVVSCHLSRSNYEMLP--------
MUL_3878|M.ulcerans_Agy99           VPGVPRNRSLGHRSHDRVWARLAEANVPVAFHLGDSGYLEIAGMWGGKET
                                     *      . *.  :: :**  :: :: *: **. . .  :.        

Mvan_4165|M.vanbaalenii_PYR-1       MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
Mflv_2489|M.gilvum_PYR-GCK          MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
TH_0524|M.thermoresistible__bu      MPPVGMPSYNHDFMVTYSLLAVNQVMSLIFDGVFDRFPNLRVVFVEHAFT
MSMEG_4808|M.smegmatis_MC2_155      LPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
MMAR_4725|M.marinum_M               TPPVGYPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVLVEHAFT
MAV_0929|M.avium_104                TPPVGFPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
MUL_3878|M.ulcerans_Agy99           FEPFAAPPDPLDKILVDDRAIHDTMASLIVHGVFDRHPTLRVASIENGSE
                                      *.. *.   * ::. .    : : ***..*.***.*.**:. :*:.  

Mvan_4165|M.vanbaalenii_PYR-1       WILPLMWRMDALYEARKSWVDIKRRPSEYVKDHIKFTTQPLDYPEDKTEL
Mflv_2489|M.gilvum_PYR-GCK          WILPLMWRMDALYEARKSWVEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
TH_0524|M.thermoresistible__bu      WILPLMWRMDAIYEARKSWLEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MSMEG_4808|M.smegmatis_MC2_155      WILPLMWRMDAIYERRKSWLNIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MMAR_4725|M.marinum_M               WILPLMWRMDALYDARKSRMDIKRKPSEYVKEHIKFTTQPLDYPEDKTEL
MAV_0929|M.avium_104                WILPLMWRMDAIYEARKSRVQIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MUL_3878|M.ulcerans_Agy99           WVHRLAKRLKKLANQHPR--SFPNDPVDALREHVWISPY---YEEDLTVL
                                    *:  *  *:. : : :    .: . * : :::*: ::.    * ** * *

Mvan_4165|M.vanbaalenii_PYR-1       SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
Mflv_2489|M.gilvum_PYR-GCK          SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFKNGIE
TH_0524|M.thermoresistible__bu      TRALEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
MSMEG_4808|M.smegmatis_MC2_155      SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAIMFRNGLK
MMAR_4725|M.marinum_M               TRAIEWMEGDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
MAV_0929|M.avium_104                TRALEWMECDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
MUL_3878|M.ulcerans_Agy99           ADRIGVDR----ILFGSDWPHGEGLESPLAFTLELTGFSRAAVQKIMRDN
                                    :  :   .    :*:.**:**   ::.*  :. .*.  :* *:       

Mvan_4165|M.vanbaalenii_PYR-1       TYKLPDTVPALEGQVRVF
Mflv_2489|M.gilvum_PYR-GCK          TYKLPDTVPALEGQVRVF
TH_0524|M.thermoresistible__bu      TYKLPETVPALEGQTRVF
MSMEG_4808|M.smegmatis_MC2_155      TYKLPDTVPVLEGQVRVF
MMAR_4725|M.marinum_M               TYHLPDTVPVLEGQTRVF
MAV_0929|M.avium_104                TYHLPETVPVLEGQVRVL
MUL_3878|M.ulcerans_Agy99           ALDFLGVTVASVA-----
                                    : .:  .. .  .