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M. thermoresistible (build 8) TH_0554 (-)

annotation: amidohydrolase family protein
coordinates: 1179124 - 1180317
length: 398

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0554--100% (398)amidohydrolase family protein
M. thermoresistible (build 8)TH_0536-e-13456.46% (395) amidohydrolase family protein
M. thermoresistible (build 8)TH_0534-e-12152.96% (389) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3792-1e-13455.70% (395) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0299-1e-1328.43% (299) putative amidohydrolase (aminocarboxymuconate-semialdehyde
M. marinum MMMAR_3988-1e-14059.19% (397) metal-dependent hydrolase
M. avium 104MAV_1625-1e-14159.45% (397) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_2994-1e-13154.68% (395) amidohydrolase family protein
M. ulcerans Agy99MUL_3849-1e-13757.93% (397) metal-dependent hydrolase
M. vanbaalenii PYR-1Mvan_2602-1e-13255.95% (395) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2994|M.smegmatis_MC2_155      MPSRILDFPVFDADNHFYEPKEALTKFLPDHRKGVIDYVDIRGRTKIVVR
Mvan_2602|M.vanbaalenii_PYR-1       MPSRILDYPVFDADNHFYEPKEALTKFLPDKRKGVIDYIDVHGRTKIMVR
Mflv_3792|M.gilvum_PYR-GCK          MPSRSLDYPVFDADNHFYEPKEALTQFLPDHRKGVIDYIDVHGRTKIVVR
MMAR_3988|M.marinum_M               MPSRELPFPVFDADNHMYEPQEALTKFLPDKRRHVIDYVQVRGRTKIVVR
MUL_3849|M.ulcerans_Agy99           MPSRELPFPVFDADNHMYEPQEALTKFLPDKRKHVIDYVQVRGRTKIVVR
MAV_1625|M.avium_104                MPSRELSFPVFDADNHMYEPQEALTKFLPDHRKHVIDYVQIRGRTKIVVR
TH_0554|M.thermoresistible__bu      MSPRSLPYPVFDIDNHMYETTDALIKFLPREHRGKVGYVELNGRKKLMVK
MAB_0299|M.abscessus_ATCC_1997      -----MTSVRIDIHAHLWS-------------DEYLSLLDGYGR------
                                         :    :* . *::.                :. ::  **      

MSMEG_2994|M.smegmatis_MC2_155      NHISDYIPNPTFEVVARPGAQEEYFR-QGSGGKSYREVLGKPMKSIPAFR
Mvan_2602|M.vanbaalenii_PYR-1       NHISDYIPNPTFEVVARPGAQEEYFR-HGSGGKSFREVMGKPMKAIPAFR
Mflv_3792|M.gilvum_PYR-GCK          NHISDYIPNPTFEVVARPGAQEEYFK-HGSGGKSFREVMGKPMKAIPAFR
MMAR_3988|M.marinum_M               GQISDYIPNPTFEVVARPGAQEEYFR-NGSRGKSYREVMGEPMKAIPAFR
MUL_3849|M.ulcerans_Agy99           GQISDYIPNPTFEVVARPGAQEEHFR-NGSGGKSYREVMGEPMKAIPAFR
MAV_1625|M.avium_104                GHISEYIPNPTFEVVARPGAQEEYFR-NGSGGKSYREILGEPMKAIPAFR
TH_0554|M.thermoresistible__bu      DRISHMIPNPTFEKVARPGSAEDYFLGNNPEGLNFREFVGEPMEVIPAFQ
MAB_0299|M.abscessus_ATCC_1997      -------PATDVHRGLGAGATRDDLD------------------------
                                           * . ..    .*: .: :                         

MSMEG_2994|M.smegmatis_MC2_155      NPEARLEVMDGLGLDYTLMFPTLASLVEERLKDDPELIHDIIHALNEWMY
Mvan_2602|M.vanbaalenii_PYR-1       NPEARLEVMDGLGLDYTLMFPTLASLVEERLKDDPELIHDIIHALNEWMY
Mflv_3792|M.gilvum_PYR-GCK          NPEARLEVLDGLGLDYTIMFPTLASLVEERMKDDPDLILDIVHALNQWMY
MMAR_3988|M.marinum_M               EPGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMY
MUL_3849|M.ulcerans_Agy99           EPGPRLEVMDELGLDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMY
MAV_1625|M.avium_104                EPGARLEVMDELGIDYALMFPTLASLVEERMKDDPEMTHDVIHALNQWMY
TH_0554|M.thermoresistible__bu      HPAPRLELMDELGIDRCVMYPTLASLIEERTTDDVVLTHAVMHALNQWMH
MAB_0299|M.abscessus_ATCC_1997      ---GRFELMDEAGVDLQILTATPASPHFEDQAAAVASAR-----FINDEY
                                        *:*::*  *:*  :: .* **   *               : :  :

MSMEG_2994|M.smegmatis_MC2_155      ETWQFDYEGRIFSTPVITLPIVDRALEELEWCLERGAKTVLVRPAPVPG-
Mvan_2602|M.vanbaalenii_PYR-1       ETWQFDYEGRIFSTPVITLPIVDRALEELEWCLERGAKTVLVRPAPVPG-
Mflv_3792|M.gilvum_PYR-GCK          ETWQFDYQGRILSTPVINLSVVDRALEELQWCLERGARTVLVRPAPVPG-
MMAR_3988|M.marinum_M               ETWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPVPG-
MUL_3849|M.ulcerans_Agy99           ETWSFNYKDRIFATPVITLPIVDRALEELEWCLQRGARTVLVRPAPVPG-
MAV_1625|M.avium_104                EQWSFNYKDRIFATPVITLPIVDRALEELEWCLERGARTVLVRPAPVPG-
TH_0554|M.thermoresistible__bu      EHWSFDYEGRIFATPVITLPIVEEAIRELHWCLERGMRTFLVRPAPVPSR
MAB_0299|M.abscessus_ATCC_1997      AKLSSEYPGRFGALASLPLPHVPAALEELARAIDELGMYGASITTSVLG-
                                       . :* .*: : . : *. *  *:.**  .::.        .:.* . 

MSMEG_2994|M.smegmatis_MC2_155      FRGTRSFGTEEFDPFWQACVKAGIPVAMHASDSGYAQYLNDWEPADEFLP
Mvan_2602|M.vanbaalenii_PYR-1       FRGTRSFGTEEFDPFWDACVKAGIPVAMHASDSGYAQYLNDWEPADEFLP
Mflv_3792|M.gilvum_PYR-GCK          YRGSRSLGLPEFDPFWDACVQAGIPVCMHASDSGYAQYLNDWEPADEFLP
MMAR_3988|M.marinum_M               YRGSRSFGFEEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDEFLP
MUL_3849|M.ulcerans_Agy99           YRGSRSFGFKEFDPFWQACIKAGIPVSMHASDSGYSEFLNVWEPGDEFLP
MAV_1625|M.avium_104                YRGSRSFGFEEFDPFWQACVRAEIPVSMHASDSGYSELLNIWEPGDEFLP
TH_0554|M.thermoresistible__bu      FGGSRSMGLPEFDPFWQEVVNAGIPVTMHASDSGYQKHLMEWEGGDEYLS
MAB_0299|M.abscessus_ATCC_1997      ----RSIADPIFDPLYAELNRRRAVLFVHPAGCGAESSL-----------
                                        **:.   ***::    .    : :*.:..*  . *           

MSMEG_2994|M.smegmatis_MC2_155      FKPTAFRMVAMGKRPIEDTMTALVCHGTFTRNPDLRILSIENGASWVPHL
Mvan_2602|M.vanbaalenii_PYR-1       FRPTAFRMVAMGKRPIEDTMAALVCHGAFTRNPDLRILSIENGASWVPYL
Mflv_3792|M.gilvum_PYR-GCK          FRPTAFRMVAMGKRPIEDTMAALVCHGALTRNPDLRILSIENGASWVPYL
MMAR_3988|M.marinum_M               FKPTAFRMLAMGKRPIEDAMGALVCHGALSRNPELRILSIENGADWVPTL
MUL_3849|M.ulcerans_Agy99           FKPTAFRMLAMSKRPIEDAMGALVCHGALSRNPELRILSIKNGADWVPTL
MAV_1625|M.avium_104                FKPTAFRSLAMGHRPVEDAFGALICHGALSRNPDLRILSIENGADWVPHL
TH_0554|M.thermoresistible__bu      FKPSALREVVMGHRAIEDTLAAMICHGALSRFPDLKILCVENGSGWVRNL
MAB_0299|M.abscessus_ATCC_1997      ITDHSLTWSIGAPIEDTVAIMHLIVAGVPSRYPDMKIVTCHLGGALPMVL
                                    :   ::     .      ::  ::  *. :* *:::*:  . *.     *

MSMEG_2994|M.smegmatis_MC2_155      FHQFEDVYAKMPQDFPEEPIQAFKRCVYVAPFWEDN--FKQMADLIGIDR
Mvan_2602|M.vanbaalenii_PYR-1       FYQFKDVYSKMPQEFPEDPIEAFRRCVYVAPFWEDD--FKKMADLCGIDR
Mflv_3792|M.gilvum_PYR-GCK          FYQFEDVYKKMPQEFPENPIDAFRRGVYVAPFWEDD--FGKMADLLGIDR
MMAR_3988|M.marinum_M               FKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDR--FAEIVKMVGTDR
MUL_3849|M.ulcerans_Agy99           FKGLKGVYKKMPNAFMEDPIEAFKRCVYISPFWEDR--FVEIVKMVGTDR
MAV_1625|M.avium_104                FKGLKGVYKKMPQAFAEDPIETFKRCVYVSPFWEDR--FAEIVNMVGTDR
TH_0554|M.thermoresistible__bu      LEQLDTAYRIMPKEFDEHPVEVFKRNIYIHPFLEDD--VPGLIEIMGADH
MAB_0299|M.abscessus_ATCC_1997      ERAHRQVTEWEATQCPEAPRDAARRLWYDTVGHDHTPALRAAVASLGVDR
                                          .    .    * * :. :*  *     :.   .       * *:

MSMEG_2994|M.smegmatis_MC2_155      VIFGSDWPHPEGLADPINLVSDLQAHGLDDEGVRKVMGRNLVDLFQVENK
Mvan_2602|M.vanbaalenii_PYR-1       VIFGSDWPHPEGLADPINLVADLEAHGLDQEGVRKVMGKNMVDLFRVENK
Mflv_3792|M.gilvum_PYR-GCK          VIFGSDWPHPEGLADPITLVDQLEENGLDEDGIRKVMGGNLVDLFKVPNK
MMAR_3988|M.marinum_M               VVFGSDWPHPEGLKDPISFVDELAG--FPPEDVAKIMGGNMMEVMKIGTP
MUL_3849|M.ulcerans_Agy99           VVFGSDWPHPEGLKDPISFVDELAG--FPPEDVAKIMGGNMMDVMKIGTA
MAV_1625|M.avium_104                VVFGSDWPHPEGLKDPISFVDELAD--FSDEDKAKIMGGNLMKLMKVSAP
TH_0554|M.thermoresistible__bu      VLFGSDYPHPEGIGDPLSFVDRLEG--VSEADKAKIMGGNAMGLLGIRVP
MAB_0299|M.abscessus_ATCC_1997      LIFGSDFPYQAGPRYVSSATYIEEG--LSAEDASAILDHNGAELLGLTGV
                                    ::****:*:  *     . .       .   .   ::. *   :: :   

MSMEG_2994|M.smegmatis_MC2_155      VVYKPDVPALVIA
Mvan_2602|M.vanbaalenii_PYR-1       VVYKPDVPALVIA
Mflv_3792|M.gilvum_PYR-GCK          VVHKPDAPALVIA
MMAR_3988|M.marinum_M               AP-QPVNA-----
MUL_3849|M.ulcerans_Agy99           AP-KPVNA-----
MAV_1625|M.avium_104                AAKKPVSA-----
TH_0554|M.thermoresistible__bu      A------------
MAB_0299|M.abscessus_ATCC_1997      -------------