For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4808 (-)

annotation: amidohydrolase family protein
coordinates: 4907782 - 4908876
length: 364

VRCVDSDVHPMPRRGELVEYIPEPWRSKYFLSHRVGEQIYYDAPDYAHAYAMRVDAFPPDGEFACSDPDM
ALRQLIMEAGSDIAILEPTHSEHRLGEATAAYCTAVNEWLADNWLDSHNNWHQRWRGSICAAIEEPQSAV
AEIEKWAGHPYMAQILIKAEPRPSWGDPKYDPIWAAATKHDIVVSCHLSRGEFETLPLPPVGLPSYNHDF
MVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFTWILPLMWRMDAIYERRKSWLNIKRKPSEYVKDH
IKFTTQPLDYPEDKTELSRAFEWMECEKILLFSSDYPHWTFDDPRWLVKHLPEHAREAIMFRNGLKTYKL
PDTVPVLEGQVRVF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4808--100% (364)amidohydrolase family protein
M. smegmatis MC2 155MSMEG_0300-e-16173.08% (364) amidohydrolase family protein
M. smegmatis MC2 155MSMEG_4807-3e-4030.00% (350) amidohydrolase family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2489-0.083.79% (364) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4725-0.080.22% (364) metal-dependent hydrolase
M. avium 104MAV_0929-0.082.64% (363) amidohydrolase family protein
M. thermoresistible (build 8)TH_0524-0.084.34% (364) amidohydrolase family protein
M. ulcerans Agy99MUL_3878-1e-1226.25% (240) metal-dependent hydrolase
M. vanbaalenii PYR-1Mvan_4165-0.084.34% (364) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2489|M.gilvum_PYR-GCK          -----------------MTVT-ANPRVPAAERIAVRCVDSDVHPAPRRGE
Mvan_4165|M.vanbaalenii_PYR-1       -----------------MTVT-ANPRVAATERIAVRCVDSDVHPTPRRGE
TH_0524|M.thermoresistible__bu      -----------------MTVT-TNPRVPATERTAIRCVDSDVHPTPRRGE
MSMEG_4808|M.smegmatis_MC2_155      ----------------------------------MRCVDSDVHPMPRRGE
MMAR_4725|M.marinum_M               -----------------MTLTHMHERVPAAERIAVRCVDSDIHPVPKRGE
MAV_0929|M.avium_104                -----------------MTLTHMQERVPAAERIAVRCVDSDVHPVPKRGE
MUL_3878|M.ulcerans_Agy99           MDSLGYKAIDVDNHYYEPLDAFTRHLDKKFRRRGVQLVTDGRHTQVIIGD
                                                                      :: * .. *.    *:

Mflv_2489|M.gilvum_PYR-GCK          -LTPYIPEPWRSKYFLTRKIGEQIYYDAPD-YAHSFAMRVDAFPSDGEFA
Mvan_4165|M.vanbaalenii_PYR-1       -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDTFPPDGEFA
TH_0524|M.thermoresistible__bu      -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDAFPPDGEFA
MSMEG_4808|M.smegmatis_MC2_155      -LVEYIPEPWRSKYFLSHRVGEQIYYDAPD-YAHAYAMRVDAFPPDGEFA
MMAR_4725|M.marinum_M               -ISPYIPEPWRSKFFLDHKVGELIYYDAPD-YAHSFAMRVDTFPADGEFP
MAV_0929|M.avium_104                -ITPYIPERWR-KFFFEHRVGELIYYDAPD-YAHAFAMRTDTFPPDGEFP
MUL_3878|M.ulcerans_Agy99           RVNRFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPASLMKVEKLELRPEYR
                                     :  :**:      :.   :.  :  : **    :  *:.: :    *: 

Mflv_2489|M.gilvum_PYR-GCK          CSDPDLAFKQLIMEAGADIAILEPAAYPARIPEAQHAMSCALNDWQANHW
Mvan_4165|M.vanbaalenii_PYR-1       CSDPDLAFKQLIMEAGADIAVLEPAAYPARIPEAQHAMSVALNDWQANHW
TH_0524|M.thermoresistible__bu      CSDPDLAFRQLIMEAGADIAILEPAAYPARTPETQHAMAVALNDWQANHW
MSMEG_4808|M.smegmatis_MC2_155      CSDPDMALRQLIMEAGSDIAILEPTHSEHRLGEATAAYCTAVNEWLADNW
MMAR_4725|M.marinum_M               GSDPDMAFRQLIMEAGSDIAILEPGGRTPRLPEAHQAYSTALNRWQANHW
MAV_0929|M.avium_104                GSDPDMAFRQLIMEAGSDIAILEPAGRTPRIGEAHQAYCSALNDWQANHW
MUL_3878|M.ulcerans_Agy99           --NRDARVVVVESQGIETIFMFPTFGCGVEEALKADIEATAASLHAFNLW
                                      : *  .  :  :.   * :: .     .        . * .    : *

Mflv_2489|M.gilvum_PYR-GCK          LDSHNNWH---ERWRGSICLAIEEPEHSVAEIERWVGHPYMAQILIKAEP
Mvan_4165|M.vanbaalenii_PYR-1       LDSHNNWH---ERWRGSICLAIEEPEKSVEEIERWAGHPYMAQILIKAEP
TH_0524|M.thermoresistible__bu      LDSHNNWH---QRWRGSICLAIEAPEDSVREIERWAGHPYMAQILIKAEP
MSMEG_4808|M.smegmatis_MC2_155      LDSHNNWH---QRWRGSICAAIEEPQSAVAEIEKWAGHPYMAQILIKAEP
MMAR_4725|M.marinum_M               LDSHNNWH---QRWRGSICAAVEDPEGAAREIEEWAGHPYMAQVLIKAEP
MAV_0929|M.avium_104                LDSRNNWH---ERWRGSICAAIEDPEGAVEQIEKWAGHPYMAQILIKAEP
MUL_3878|M.ulcerans_Agy99           LDEDWGFDRPDHRIIAAPMISLADPEKALQEVEFVLERG-ARMVHVRPAP
                                    **.  .:.   .*  .:   ::  *: :  ::*    :     : ::. *

Mflv_2489|M.gilvum_PYR-GCK          RP------SWGNPKYDPIWAAAAKHDIPVSCHLSRSHYDELP--------
Mvan_4165|M.vanbaalenii_PYR-1       RP------SWGNPKYDPIWAAATKHDITVSCHLSRSHYDELP--------
TH_0524|M.thermoresistible__bu      RP------SWGDPKYDPIWAAAAKHDITVSCHLSRSHHEELP--------
MSMEG_4808|M.smegmatis_MC2_155      RP------SWGDPKYDPIWAAATKHDIVVSCHLSRGEFETLP--------
MMAR_4725|M.marinum_M               RP------CWGHPMYNPIWAAATKHDITVSCHLSRSNFEMLP--------
MAV_0929|M.avium_104                RP------SWGHPKYDPIWAAATKHDIVVSCHLSRSNYEMLP--------
MUL_3878|M.ulcerans_Agy99           VPGVPRNRSLGHRSHDRVWARLAEANVPVAFHLGDSGYLEIAGMWGGKET
                                     *      . *.  :: :**  :: :: *: **. . .  :.        

Mflv_2489|M.gilvum_PYR-GCK          MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
Mvan_4165|M.vanbaalenii_PYR-1       MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
TH_0524|M.thermoresistible__bu      MPPVGMPSYNHDFMVTYSLLAVNQVMSLIFDGVFDRFPNLRVVFVEHAFT
MSMEG_4808|M.smegmatis_MC2_155      LPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
MMAR_4725|M.marinum_M               TPPVGYPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVLVEHAFT
MAV_0929|M.avium_104                TPPVGFPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
MUL_3878|M.ulcerans_Agy99           FEPFAAPPDPLDKILVDDRAIHDTMASLIVHGVFDRHPTLRVASIENGSE
                                      *.. *.   * ::. .    : : ***..*.***.*.**:. :*:.  

Mflv_2489|M.gilvum_PYR-GCK          WILPLMWRMDALYEARKSWVEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
Mvan_4165|M.vanbaalenii_PYR-1       WILPLMWRMDALYEARKSWVDIKRRPSEYVKDHIKFTTQPLDYPEDKTEL
TH_0524|M.thermoresistible__bu      WILPLMWRMDAIYEARKSWLEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MSMEG_4808|M.smegmatis_MC2_155      WILPLMWRMDAIYERRKSWLNIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MMAR_4725|M.marinum_M               WILPLMWRMDALYDARKSRMDIKRKPSEYVKEHIKFTTQPLDYPEDKTEL
MAV_0929|M.avium_104                WILPLMWRMDAIYEARKSRVQIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MUL_3878|M.ulcerans_Agy99           WVHRLAKRLKKLANQHPR--SFPNDPVDALREHVWISPY---YEEDLTVL
                                    *:  *  *:. : : :    .: . * : :::*: ::.    * ** * *

Mflv_2489|M.gilvum_PYR-GCK          SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFKNGIE
Mvan_4165|M.vanbaalenii_PYR-1       SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
TH_0524|M.thermoresistible__bu      TRALEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
MSMEG_4808|M.smegmatis_MC2_155      SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAIMFRNGLK
MMAR_4725|M.marinum_M               TRAIEWMEGDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
MAV_0929|M.avium_104                TRALEWMECDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
MUL_3878|M.ulcerans_Agy99           ADRIGVDR----ILFGSDWPHGEGLESPLAFTLELTGFSRAAVQKIMRDN
                                    :  :   .    :*:.**:**   ::.*  :. .*.  :* *:       

Mflv_2489|M.gilvum_PYR-GCK          TYKLPDTVPALEGQVRVF
Mvan_4165|M.vanbaalenii_PYR-1       TYKLPDTVPALEGQVRVF
TH_0524|M.thermoresistible__bu      TYKLPETVPALEGQTRVF
MSMEG_4808|M.smegmatis_MC2_155      TYKLPDTVPVLEGQVRVF
MMAR_4725|M.marinum_M               TYHLPDTVPVLEGQTRVF
MAV_0929|M.avium_104                TYHLPETVPVLEGQVRVL
MUL_3878|M.ulcerans_Agy99           ALDFLGVTVASVA-----
                                    : .:  .. .  .