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MTLTHMHERVPAAERIAVRCVDSDIHPVPKRGEISPYIPEPWRSKFFLDHKVGELIYYDAPDYAHSFAMR VDTFPADGEFPGSDPDMAFRQLIMEAGSDIAILEPGGRTPRLPEAHQAYSTALNRWQANHWLDSHNNWHQ RWRGSICAAVEDPEGAAREIEEWAGHPYMAQVLIKAEPRPCWGHPMYNPIWAAATKHDITVSCHLSRSNF EMLPTPPVGYPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVLVEHAFTWILPLMWRMDALYDAR KSRMDIKRKPSEYVKEHIKFTTQPLDYPEDKTELTRAIEWMEGDKILLYSSDYPHWTFDDPRWLVKHLPK AARDAVMYKNGIATYHLPDTVPVLEGQTRVF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4725 | - | - | 100% (381) | metal-dependent hydrolase |
| M. marinum M | MMAR_4724 | - | 3e-40 | 27.47% (364) | metal-dependent hydrolase |
| M. marinum M | MMAR_4014 | - | 2e-11 | 27.00% (237) | metal-dependent hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2489 | - | 0.0 | 79.53% (381) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | MAV_0929 | - | 0.0 | 89.21% (380) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_4808 | - | 0.0 | 80.22% (364) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_0524 | - | 0.0 | 79.53% (381) | amidohydrolase family protein |
| M. ulcerans Agy99 | MUL_3878 | - | 1e-11 | 27.00% (237) | metal-dependent hydrolase |
| M. vanbaalenii PYR-1 | Mvan_4165 | - | 0.0 | 79.53% (381) | amidohydrolase 2 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4725|M.marinum_M -----------------MTLTHMHERVPAAERIAVRCVDSDIHPVPKRGE
MAV_0929|M.avium_104 -----------------MTLTHMQERVPAAERIAVRCVDSDVHPVPKRGE
Mflv_2489|M.gilvum_PYR-GCK -----------------MTVT-ANPRVPAAERIAVRCVDSDVHPAPRRGE
Mvan_4165|M.vanbaalenii_PYR-1 -----------------MTVT-ANPRVAATERIAVRCVDSDVHPTPRRGE
TH_0524|M.thermoresistible__bu -----------------MTVT-TNPRVPATERTAIRCVDSDVHPTPRRGE
MSMEG_4808|M.smegmatis_MC2_155 ----------------------------------MRCVDSDVHPMPRRGE
MUL_3878|M.ulcerans_Agy99 MDSLGYKAIDVDNHYYEPLDAFTRHLDKKFRRRGVQLVTDGRHTQVIIGD
:: * .. *. *:
MMAR_4725|M.marinum_M -ISPYIPEPWRSKFFLDHKVGELIYYDAPD-YAHSFAMRVDTFPADGEFP
MAV_0929|M.avium_104 -ITPYIPERWR-KFFFEHRVGELIYYDAPD-YAHAFAMRTDTFPPDGEFP
Mflv_2489|M.gilvum_PYR-GCK -LTPYIPEPWRSKYFLTRKIGEQIYYDAPD-YAHSFAMRVDAFPSDGEFA
Mvan_4165|M.vanbaalenii_PYR-1 -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDTFPPDGEFA
TH_0524|M.thermoresistible__bu -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDAFPPDGEFA
MSMEG_4808|M.smegmatis_MC2_155 -LVEYIPEPWRSKYFLSHRVGEQIYYDAPD-YAHAYAMRVDAFPPDGEFA
MUL_3878|M.ulcerans_Agy99 RVNRFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPASLMKVEKLELRPEYR
: :**: :. :. : : ** : *:.: : *:
MMAR_4725|M.marinum_M GSDPDMAFRQLIMEAGSDIAILEPGGRTPRLPEAHQAYSTALNRWQANHW
MAV_0929|M.avium_104 GSDPDMAFRQLIMEAGSDIAILEPAGRTPRIGEAHQAYCSALNDWQANHW
Mflv_2489|M.gilvum_PYR-GCK CSDPDLAFKQLIMEAGADIAILEPAAYPARIPEAQHAMSCALNDWQANHW
Mvan_4165|M.vanbaalenii_PYR-1 CSDPDLAFKQLIMEAGADIAVLEPAAYPARIPEAQHAMSVALNDWQANHW
TH_0524|M.thermoresistible__bu CSDPDLAFRQLIMEAGADIAILEPAAYPARTPETQHAMAVALNDWQANHW
MSMEG_4808|M.smegmatis_MC2_155 CSDPDMALRQLIMEAGSDIAILEPTHSEHRLGEATAAYCTAVNEWLADNW
MUL_3878|M.ulcerans_Agy99 --NRDARVVVVESQGIETIFMFPTFGCGVEEALKADIEATAASLHAFNLW
: * . : :. * :: . . . * . : *
MMAR_4725|M.marinum_M LDSHNNWH---QRWRGSICAAVEDPEGAAREIEEWAGHPYMAQVLIKAEP
MAV_0929|M.avium_104 LDSRNNWH---ERWRGSICAAIEDPEGAVEQIEKWAGHPYMAQILIKAEP
Mflv_2489|M.gilvum_PYR-GCK LDSHNNWH---ERWRGSICLAIEEPEHSVAEIERWVGHPYMAQILIKAEP
Mvan_4165|M.vanbaalenii_PYR-1 LDSHNNWH---ERWRGSICLAIEEPEKSVEEIERWAGHPYMAQILIKAEP
TH_0524|M.thermoresistible__bu LDSHNNWH---QRWRGSICLAIEAPEDSVREIERWAGHPYMAQILIKAEP
MSMEG_4808|M.smegmatis_MC2_155 LDSHNNWH---QRWRGSICAAIEEPQSAVAEIEKWAGHPYMAQILIKAEP
MUL_3878|M.ulcerans_Agy99 LDEDWGFDRPDHRIIAAPMISLADPEKALQEVEFVLERG-ARMVHVRPAP
**. .:. .* .: :: *: : ::* : : ::. *
MMAR_4725|M.marinum_M RP------CWGHPMYNPIWAAATKHDITVSCHLSRSNFEMLP--------
MAV_0929|M.avium_104 RP------SWGHPKYDPIWAAATKHDIVVSCHLSRSNYEMLP--------
Mflv_2489|M.gilvum_PYR-GCK RP------SWGNPKYDPIWAAAAKHDIPVSCHLSRSHYDELP--------
Mvan_4165|M.vanbaalenii_PYR-1 RP------SWGNPKYDPIWAAATKHDITVSCHLSRSHYDELP--------
TH_0524|M.thermoresistible__bu RP------SWGDPKYDPIWAAAAKHDITVSCHLSRSHHEELP--------
MSMEG_4808|M.smegmatis_MC2_155 RP------SWGDPKYDPIWAAATKHDIVVSCHLSRGEFETLP--------
MUL_3878|M.ulcerans_Agy99 VPGVPRNRSLGHRSHDRVWARLAEANVPVAFHLGDSGYLEIAGMWGGKET
* . *. :: :** :: :: *: **. . . :.
MMAR_4725|M.marinum_M TPPVGYPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVLVEHAFT
MAV_0929|M.avium_104 TPPVGFPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
Mflv_2489|M.gilvum_PYR-GCK MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
Mvan_4165|M.vanbaalenii_PYR-1 MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
TH_0524|M.thermoresistible__bu MPPVGMPSYNHDFMVTYSLLAVNQVMSLIFDGVFDRFPNLRVVFVEHAFT
MSMEG_4808|M.smegmatis_MC2_155 LPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
MUL_3878|M.ulcerans_Agy99 FEPFAAPPDPLDKILVDDRAIHDTMASLIVHGVFDRHPTLRVASIENGSE
*.. *. * ::. . : : ***..*.***.*.**:. :*:.
MMAR_4725|M.marinum_M WILPLMWRMDALYDARKSRMDIKRKPSEYVKEHIKFTTQPLDYPEDKTEL
MAV_0929|M.avium_104 WILPLMWRMDAIYEARKSRVQIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
Mflv_2489|M.gilvum_PYR-GCK WILPLMWRMDALYEARKSWVEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
Mvan_4165|M.vanbaalenii_PYR-1 WILPLMWRMDALYEARKSWVDIKRRPSEYVKDHIKFTTQPLDYPEDKTEL
TH_0524|M.thermoresistible__bu WILPLMWRMDAIYEARKSWLEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MSMEG_4808|M.smegmatis_MC2_155 WILPLMWRMDAIYERRKSWLNIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MUL_3878|M.ulcerans_Agy99 WVHRLAKRLKKLANQHPR--SFPNDPVDALREHVWISPY---YEEDLTVL
*: * *:. : : : .: . * : :::*: ::. * ** * *
MMAR_4725|M.marinum_M TRAIEWMEGDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
MAV_0929|M.avium_104 TRALEWMECDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
Mflv_2489|M.gilvum_PYR-GCK SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFKNGIE
Mvan_4165|M.vanbaalenii_PYR-1 SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
TH_0524|M.thermoresistible__bu TRALEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
MSMEG_4808|M.smegmatis_MC2_155 SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAIMFRNGLK
MUL_3878|M.ulcerans_Agy99 ADRIGVDR----ILFGSDWPHGEGLESPLAFTLELTGFSRAAVQKIMRDN
: : . :*:.**:** ::.* :. .*. :* *:
MMAR_4725|M.marinum_M TYHLPDTVPVLEGQTRVF
MAV_0929|M.avium_104 TYHLPETVPVLEGQVRVL
Mflv_2489|M.gilvum_PYR-GCK TYKLPDTVPALEGQVRVF
Mvan_4165|M.vanbaalenii_PYR-1 TYKLPDTVPALEGQVRVF
TH_0524|M.thermoresistible__bu TYKLPETVPALEGQTRVF
MSMEG_4808|M.smegmatis_MC2_155 TYKLPDTVPVLEGQVRVF
MUL_3878|M.ulcerans_Agy99 ALDFLGVTVASVA-----
: .: .. . .