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M. avium 104 MAV_0929 (-)

annotation: amidohydrolase family protein
coordinates: 871755 - 872897
length: 380

TLTHMQERVPAAERIAVRCVDSDVHPVPKRGEITPYIPERWRKFFFEHRVGELIYYDAPDYAHAFAMRTD
TFPPDGEFPGSDPDMAFRQLIMEAGSDIAILEPAGRTPRIGEAHQAYCSALNDWQANHWLDSRNNWHERW
RGSICAAIEDPEGAVEQIEKWAGHPYMAQILIKAEPRPSWGHPKYDPIWAAATKHDIVVSCHLSRSNYEM
LPTPPVGFPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFTWILPLMWRMDAIYEARKS
RVQIKRKPSEYVKDHIKFTTQPLDYPEDKTELTRALEWMECDKILLYSSDYPHWTFDDPRWLVKHLPKAA
RDAVMYKNGIATYHLPETVPVLEGQVRVL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_0929--100% (380)amidohydrolase family protein
M. avium 104MAV_0930-9e-4128.09% (356) amidohydrolase family protein
M. avium 104MAV_3544-7e-1426.53% (294) amidohydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_2489-0.081.32% (380) amidohydrolase 2
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4725-0.089.21% (380) metal-dependent hydrolase
M. smegmatis MC2 155MSMEG_4808-0.082.64% (363) amidohydrolase family protein
M. thermoresistible (build 8)TH_0524-0.080.53% (380) amidohydrolase family protein
M. ulcerans Agy99MUL_3878-3e-1226.38% (235) metal-dependent hydrolase
M. vanbaalenii PYR-1Mvan_4165-0.081.05% (380) amidohydrolase 2

CLUSTAL 2.0.9 multiple sequence alignment


MAV_0929|M.avium_104                -----------------MTLTHMQERVPAAERIAVRCVDSDVHPVPKRGE
MMAR_4725|M.marinum_M               -----------------MTLTHMHERVPAAERIAVRCVDSDIHPVPKRGE
Mflv_2489|M.gilvum_PYR-GCK          -----------------MTVT-ANPRVPAAERIAVRCVDSDVHPAPRRGE
Mvan_4165|M.vanbaalenii_PYR-1       -----------------MTVT-ANPRVAATERIAVRCVDSDVHPTPRRGE
TH_0524|M.thermoresistible__bu      -----------------MTVT-TNPRVPATERTAIRCVDSDVHPTPRRGE
MSMEG_4808|M.smegmatis_MC2_155      ----------------------------------MRCVDSDVHPMPRRGE
MUL_3878|M.ulcerans_Agy99           MDSLGYKAIDVDNHYYEPLDAFTRHLDKKFRRRGVQLVTDGRHTQVIIGD
                                                                      :: * .. *.    *:

MAV_0929|M.avium_104                -ITPYIPERWR-KFFFEHRVGELIYYDAPD-YAHAFAMRTDTFPPDGEFP
MMAR_4725|M.marinum_M               -ISPYIPEPWRSKFFLDHKVGELIYYDAPD-YAHSFAMRVDTFPADGEFP
Mflv_2489|M.gilvum_PYR-GCK          -LTPYIPEPWRSKYFLTRKIGEQIYYDAPD-YAHSFAMRVDAFPSDGEFA
Mvan_4165|M.vanbaalenii_PYR-1       -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDTFPPDGEFA
TH_0524|M.thermoresistible__bu      -LLPYIPEPWRSKYFLTRKVGEQIYYDAPD-YAHSYAMRVDAFPPDGEFA
MSMEG_4808|M.smegmatis_MC2_155      -LVEYIPEPWRSKYFLSHRVGEQIYYDAPD-YAHAYAMRVDAFPPDGEFA
MUL_3878|M.ulcerans_Agy99           RVNRFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPASLMKVEKLELRPEYR
                                     :  :**:      :.   :.  :  : **    :  *:.: :    *: 

MAV_0929|M.avium_104                GSDPDMAFRQLIMEAGSDIAILEPAGRTPRIGEAHQAYCSALNDWQANHW
MMAR_4725|M.marinum_M               GSDPDMAFRQLIMEAGSDIAILEPGGRTPRLPEAHQAYSTALNRWQANHW
Mflv_2489|M.gilvum_PYR-GCK          CSDPDLAFKQLIMEAGADIAILEPAAYPARIPEAQHAMSCALNDWQANHW
Mvan_4165|M.vanbaalenii_PYR-1       CSDPDLAFKQLIMEAGADIAVLEPAAYPARIPEAQHAMSVALNDWQANHW
TH_0524|M.thermoresistible__bu      CSDPDLAFRQLIMEAGADIAILEPAAYPARTPETQHAMAVALNDWQANHW
MSMEG_4808|M.smegmatis_MC2_155      CSDPDMALRQLIMEAGSDIAILEPTHSEHRLGEATAAYCTAVNEWLADNW
MUL_3878|M.ulcerans_Agy99           --NRDARVVVVESQGIETIFMFPTFGCGVEEALKADIEATAASLHAFNLW
                                      : *  .  :  :.   * :: .     .        . * .    : *

MAV_0929|M.avium_104                LDSRNNWH---ERWRGSICAAIEDPEGAVEQIEKWAGHPYMAQILIKAEP
MMAR_4725|M.marinum_M               LDSHNNWH---QRWRGSICAAVEDPEGAAREIEEWAGHPYMAQVLIKAEP
Mflv_2489|M.gilvum_PYR-GCK          LDSHNNWH---ERWRGSICLAIEEPEHSVAEIERWVGHPYMAQILIKAEP
Mvan_4165|M.vanbaalenii_PYR-1       LDSHNNWH---ERWRGSICLAIEEPEKSVEEIERWAGHPYMAQILIKAEP
TH_0524|M.thermoresistible__bu      LDSHNNWH---QRWRGSICLAIEAPEDSVREIERWAGHPYMAQILIKAEP
MSMEG_4808|M.smegmatis_MC2_155      LDSHNNWH---QRWRGSICAAIEEPQSAVAEIEKWAGHPYMAQILIKAEP
MUL_3878|M.ulcerans_Agy99           LDEDWGFDRPDHRIIAAPMISLADPEKALQEVEFVLERG-ARMVHVRPAP
                                    **.  .:.   .*  .:   ::  *: :  ::*    :     : ::. *

MAV_0929|M.avium_104                RP------SWGHPKYDPIWAAATKHDIVVSCHLSRSNYEMLP--------
MMAR_4725|M.marinum_M               RP------CWGHPMYNPIWAAATKHDITVSCHLSRSNFEMLP--------
Mflv_2489|M.gilvum_PYR-GCK          RP------SWGNPKYDPIWAAAAKHDIPVSCHLSRSHYDELP--------
Mvan_4165|M.vanbaalenii_PYR-1       RP------SWGNPKYDPIWAAATKHDITVSCHLSRSHYDELP--------
TH_0524|M.thermoresistible__bu      RP------SWGDPKYDPIWAAAAKHDITVSCHLSRSHHEELP--------
MSMEG_4808|M.smegmatis_MC2_155      RP------SWGDPKYDPIWAAATKHDIVVSCHLSRGEFETLP--------
MUL_3878|M.ulcerans_Agy99           VPGVPRNRSLGHRSHDRVWARLAEANVPVAFHLGDSGYLEIAGMWGGKET
                                     *      . *.  :: :**  :: :: *: **. . .  :.        

MAV_0929|M.avium_104                TPPVGFPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
MMAR_4725|M.marinum_M               TPPVGYPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVLVEHAFT
Mflv_2489|M.gilvum_PYR-GCK          MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
Mvan_4165|M.vanbaalenii_PYR-1       MPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGTFDRHPNLRIVFVEHAFT
TH_0524|M.thermoresistible__bu      MPPVGMPSYNHDFMVTYSLLAVNQVMSLIFDGVFDRFPNLRVVFVEHAFT
MSMEG_4808|M.smegmatis_MC2_155      LPPVGLPSYNHDFMVTYSLLAANQVMSLIFDGVFDRFPTLRIVFVEHAFT
MUL_3878|M.ulcerans_Agy99           FEPFAAPPDPLDKILVDDRAIHDTMASLIVHGVFDRHPTLRVASIENGSE
                                      *.. *.   * ::. .    : : ***..*.***.*.**:. :*:.  

MAV_0929|M.avium_104                WILPLMWRMDAIYEARKSRVQIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MMAR_4725|M.marinum_M               WILPLMWRMDALYDARKSRMDIKRKPSEYVKEHIKFTTQPLDYPEDKTEL
Mflv_2489|M.gilvum_PYR-GCK          WILPLMWRMDALYEARKSWVEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
Mvan_4165|M.vanbaalenii_PYR-1       WILPLMWRMDALYEARKSWVDIKRRPSEYVKDHIKFTTQPLDYPEDKTEL
TH_0524|M.thermoresistible__bu      WILPLMWRMDAIYEARKSWLEIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MSMEG_4808|M.smegmatis_MC2_155      WILPLMWRMDAIYERRKSWLNIKRKPSEYVKDHIKFTTQPLDYPEDKTEL
MUL_3878|M.ulcerans_Agy99           WVHRLAKRLKKLANQHPR--SFPNDPVDALREHVWISPY---YEEDLTVL
                                    *:  *  *:. : : :    .: . * : :::*: ::.    * ** * *

MAV_0929|M.avium_104                TRALEWMECDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
MMAR_4725|M.marinum_M               TRAIEWMEGDKILLYSSDYPHWT-FDDPRWLVKHLPKAARDAVMYKNGIA
Mflv_2489|M.gilvum_PYR-GCK          SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFKNGIE
Mvan_4165|M.vanbaalenii_PYR-1       SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
TH_0524|M.thermoresistible__bu      TRALEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAVMFRNGIE
MSMEG_4808|M.smegmatis_MC2_155      SRAFEWMECEKILLFSSDYPHWT-FDDPRWLVKHLPEHAREAIMFRNGLK
MUL_3878|M.ulcerans_Agy99           ADRIGVDR----ILFGSDWPHGEGLESPLAFTLELTGFSRAAVQKIMRDN
                                    :  :   .    :*:.**:**   ::.*  :. .*.  :* *:       

MAV_0929|M.avium_104                TYHLPETVPVLEGQVRVL
MMAR_4725|M.marinum_M               TYHLPDTVPVLEGQTRVF
Mflv_2489|M.gilvum_PYR-GCK          TYKLPDTVPALEGQVRVF
Mvan_4165|M.vanbaalenii_PYR-1       TYKLPDTVPALEGQVRVF
TH_0524|M.thermoresistible__bu      TYKLPETVPALEGQTRVF
MSMEG_4808|M.smegmatis_MC2_155      TYKLPDTVPVLEGQVRVF
MUL_3878|M.ulcerans_Agy99           ALDFLGVTVASVA-----
                                    : .:  .. .  .