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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0136 | - | 100% (458) | PROBABLE CYTOCHROME P450 137 CYP137 | |
| M. thermoresistible (build 8) | TH_0082 | - | 7e-63 | 33.26% (436) | putative cytochrome P450 135B1 |
| M. thermoresistible (build 8) | TH_2672 | - | 8e-59 | 34.91% (424) | PUTATIVE cytochrome P450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3710c | cyp137 | 1e-145 | 60.00% (440) | cytochrome P450 137 |
| M. gilvum PYR-GCK | Mflv_1104 | - | 2e-60 | 34.38% (413) | cytochrome P450 |
| M. tuberculosis H37Rv | Rv3685c | cyp137 | 1e-145 | 60.23% (440) | cytochrome P450 137 |
| M. leprae Br4923 | MLBr_02088 | - | 1e-17 | 28.26% (322) | putative cytochrome p450 |
| M. abscessus ATCC 19977 | MAB_4693 | - | 1e-67 | 35.60% (455) | cytochrome P450 |
| M. marinum M | MMAR_5175 | cyp137A2 | 1e-146 | 59.95% (442) | cytochrome P450 137A2 Cyp137A2 |
| M. avium 104 | MAV_5160 | - | 2e-64 | 34.86% (436) | cytochrome P450 monooxygenase |
| M. smegmatis MC2 155 | MSMEG_1213 | - | 1e-65 | 36.25% (411) | cytochrome P450 monooxygenase |
| M. ulcerans Agy99 | MUL_3402 | cyp136A2 | 9e-31 | 28.90% (436) | cytochrome P450 136A2 Cyp136A2 |
| M. vanbaalenii PYR-1 | Mvan_0675 | - | 0.0 | 71.40% (458) | cytochrome P450 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_0136|M.thermoresistible__bu ---------------------------------------------VRPPS
Mvan_0675|M.vanbaalenii_PYR-1 ---------------------------------------------MRPPS
Mb3710c|M.bovis_AF2122/97 -------MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPG
Rv3685c|M.tuberculosis_H37Rv -------MVLRSLASPAALTDPKRCASVVGVAAFAVRREHAPDALGGPPG
MMAR_5175|M.marinum_M ----------MPASAPSARTPP---------------------ALRRPPG
MAB_4693|M.abscessus_ATCC_1997 ---------------------------------------------MSKTA
MSMEG_1213|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1104|M.gilvum_PYR-GCK --------------------------------------------------
MAV_5160|M.avium_104 ----------------------------------------MSEVATAPLA
MUL_3402|M.ulcerans_Agy99 MATISTPAYLLDQAQRRLTPSFNNFPGMGMVERWLLKTQFPETTLADPPP
MLBr_02088|M.leprae_Br4923 ---------------------------MRTCVPTRTCVYAFIEYLSHNRP
TH_0136|M.thermoresistible__bu LPAPAPLS---AVFGAGYAAAYAVGGNRMVARMLKRYGPVVALPVLGYGT
Mvan_0675|M.vanbaalenii_PYR-1 LPAPPPLA---PVFGGLYAAAFGMGGQAIVAQMVRRYGPVVALPVLGFGK
Mb3710c|M.bovis_AF2122/97 LPAPRGFR---AAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGD
Rv3685c|M.tuberculosis_H37Rv LPAPRGFR---AAFAAAYAVAYLAGGERRMLRLIRRYGPIMTMPILSLGD
MMAR_5175|M.marinum_M LPAPRRLR---TVFAAAYAVAYLVGGERRMLRLIRRYGPIMTMPILSLGD
MAB_4693|M.abscessus_ATCC_1997 KIALPPGP---PLPLAVQSILMASYGLRFLAGCQRRYGNMFTLRIPLSGK
MSMEG_1213|M.smegmatis_MC2_155 ----------------MQTAMMLRHWSRFVSACRRRYGDVFTLRIASMGT
Mflv_1104|M.gilvum_PYR-GCK -MRLPPTP---RIPRFLQGLGFSLSRQWTVAQVVRRYGDVFTMTLPVFGK
MAV_5160|M.avium_104 AVHLPPAV---RGPKLLQGIGFAVSRRTMMRRLSRRYGNVFTLRLPMWGP
MUL_3402|M.ulcerans_Agy99 GSDLKPVVGDAGLPILGHLIEMLRGGPDYLMFLYRTKGPVVFGDSPVLSA
MLBr_02088|M.leprae_Br4923 MGTNPPSLVEAQMLLLRLIDPGTRADPFPVYRALIDYGPMQLPGMPLTVF
: * :
TH_0136|M.thermoresistible__bu VVAVADPALARQVFAE----KPDVLLGGDGVGPAAAIYGPRSMFVQEEPE
Mvan_0675|M.vanbaalenii_PYR-1 VVAVADAALAKQVFTE----NPDVLLGGEGVGPAAAIYGPRSMFVLEEPG
Mb3710c|M.bovis_AF2122/97 VAIVSDSALAKEVFTA----PTDVLLGGEGVGPAAAIYGSGSMFVQEEPQ
Rv3685c|M.tuberculosis_H37Rv VAIVSDSALAKEVFTA----PTDVLLGGEGVGPAAAIYGSGSMFVQEEPE
MMAR_5175|M.marinum_M VAIVSDPALVKEVFTA----PPDVLLGGEGVGPAAAIYGAGSMFVQEEPE
MAB_4693|M.abscessus_ATCC_1997 VVYLADPADIKTVYAG----DPHVFHSGEAHWFFRGLLGDSSLFVLDEDE
MSMEG_1213|M.smegmatis_MC2_155 WVYLADPADIKTVFAG----DPTVFHAGEANSMLSGLLGETSVLVIDEDV
Mflv_1104|M.gilvum_PYR-GCK TVLVTDPALAKQLFMA----NTD--DVGNIQPNLSRVLGSGSVFALDGTD
MAV_5160|M.avium_104 VVMVSDPQLAKQIFTT----SPD--ELGNIQPNLSRLFGSGSVFGLEGDD
MUL_3402|M.ulcerans_Agy99 VVALG-PDAAQVIYSN----RNKDYSQQGWVPVIGPFFRRG-LMLLDFEE
MLBr_02088|M.leprae_Br4923 SSFSDCDEALRHPLSASDRLKATLAQQAIAAGAEPRPFYASSFMFLDPPD
: .: :
TH_0136|M.thermoresistible__bu HLRRRRLLIPPLHGAALAGHVPVIEAATRSAMA-SWPVGRP-MRMLDAAR
Mvan_0675|M.vanbaalenii_PYR-1 HLRRRRLLTPPLHGELLGSYVPIIESSTRSAMA-TWPVGRP-MRMLDAAR
Mb3710c|M.bovis_AF2122/97 HLRRRKLLTPPLHGAALDRYVPIIENSTRAAMH-TWPVDRP-FAMLTVAR
Rv3685c|M.tuberculosis_H37Rv HLRRRKLLTPPLHGAALDRYVPIIENSTRAAMH-TWPVDRP-FAMLTVAR
MMAR_5175|M.marinum_M HLRRRKLLTPPLHGTALGRYVPIIEESTRAAMR-DWPVDRP-FELLGAAR
MAB_4693|M.abscessus_ATCC_1997 HHHQRRLLMPAFHRDAVARQATQMAQIAAANIA-EWPVGES-FPVAPRTT
MSMEG_1213|M.smegmatis_MC2_155 HRDRRRLMLAPFARDAVARQTGVMAEVAATNIA-SWPVGTP-FPVAPKMA
Mflv_1104|M.gilvum_PYR-GCK HRLRRKLLTPPFHGKSIKNYERIFEEETLREAA-SWPEGQP-FETLEPMM
MAV_5160|M.avium_104 HRRRRRLLAPPFHGKSMKNYESIIEEETLRETA-GWPEGES-FPTLPPMM
MUL_3402|M.ulcerans_Agy99 HMFHRRIMQQAFVRPRLVGYVEHMDEVASRAIAGEWATNDARFLLYPAMK
MLBr_02088|M.leprae_Br4923 HTRLRKLVSKAFAPKVVQALEGDIAALVDSLLD-------------KGAA
* *::: .: : : .
TH_0136|M.thermoresistible__bu DLTLDVIIRVIFGVHDPAEVARLAAPFETLLALAVSVQTPVRYALRRAGA
Mvan_0675|M.vanbaalenii_PYR-1 ELTLDVIVQVVFGVHDPESVARFGKPFHELLDLALSEETPVRYALRRFGA
Mb3710c|M.bovis_AF2122/97 SLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGA
Rv3685c|M.tuberculosis_H37Rv SLMLDVIVKVIFGVDDPEEVRRLGRPFERLLNLGVSEQLTVRYALRRLGA
MMAR_5175|M.marinum_M ALMLDVIVKVIFGVDDPDEVRRLGRPFERLLDLGVSEQLTVRYALRRAGA
MAB_4693|M.abscessus_ATCC_1997 DITLEVILRTVIGASDPVRLAALRKVVPRLLYMKP-WETPA-ITNPGLRR
MSMEG_1213|M.smegmatis_MC2_155 EIALEVILRTVIGATEPARLAALRHVMPQLLGIGP-WQSLA-IASPGLQR
Mflv_1104|M.gilvum_PYR-GCK RITLNAILRAVFGADG-AHLDELRRIIPPWVTLGSRLAVLP-TPHRTYGR
MAV_5160|M.avium_104 RITLNAILRAVFGAEG-AELDELRRLIPPWVTLGSRLAALP-KPQR-YPR
MUL_3402|M.ulcerans_Agy99 KLTLDIASMVFMGHEPGTDHELVTKVNRAFTTTTRAGNAVIRTSVPPFTW
MLBr_02088|M.leprae_Br4923 AGQFDVIADLAFPLAVAVICRLLGVPYEDAPEFGRVSALLVQSVDPFITI
:: : .
TH_0136|M.thermoresistible__bu LRFWHAYRDANRRIDELVRPLIAARR-VPDAGPRDDILSMLVAARTEDGD
Mvan_0675|M.vanbaalenii_PYR-1 LRRWGRLSDANRRIDELVLPLIAERRSDPLSAERADILSMLANSHTDDGE
Mb3710c|M.bovis_AF2122/97 LRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGE
Rv3685c|M.tuberculosis_H37Rv LRVWPARARANTEIDDVVMALIAQRRADPRLGERHDVLSLLVSARGESGE
MMAR_5175|M.marinum_M LRVWPQRARAYREIEDVVMPLIAQRRSDLGRTEQRDILGLLISARGDDGE
MAB_4693|M.abscessus_ATCC_1997 YWPWTAVGRRMAETDALLYAEIAERRADPNLTERTDVLAMLVRATDDDGR
MSMEG_1213|M.smegmatis_MC2_155 RRPWRTLQRNLAEADRLLYAEIAACRAGPDLASRPDALAMLVRAANDEGR
Mflv_1104|M.gilvum_PYR-GCK FSPWGRLARYRRRYDEVIGRLIDAVQADPNFESRDDVLALLLRSTYEDGS
MAV_5160|M.avium_104 FGPWGQLDRWRRQYDGVIERLIAAEQADPNFAERTDVLALLLRSTYDDGA
MUL_3402|M.ulcerans_Agy99 WR--------GIRARQLLENYFAARVTERRGQEGNDLLTVLCHTADEDGN
MLBr_02088|M.leprae_Br4923 TGEPPEATEERLRAGVWLRDYLEQLVKCRRGTPGEDLISRLIELD-ESGD
. : : * : * :.*
TH_0136|M.thermoresistible__bu RLTDDEIRDDLITLVLAGHETTATTLAWLIDYLVHHPAALDRVRAEAAPG
Mvan_0675|M.vanbaalenii_PYR-1 TLSDNEIRDDLITLVLAGHETTATTLSWLIDLLLHHPRALARVRAEAVSG
Mb3710c|M.bovis_AF2122/97 QLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGG
Rv3685c|M.tuberculosis_H37Rv QLSDSEIRDDLITLVLAGHETTATTLAWAFDLLLHHPDALRRVRAEAVGG
MMAR_5175|M.marinum_M QLSDQEIRDDLITLMLAGHETTATTLAWVFDLLLHHPDALRRVQEEAEGG
MAB_4693|M.abscessus_ATCC_1997 TMSDQELRDHLLTSIAAGHETTATALSWVLERLTRHPDALLKAAQAAEAS
MSMEG_1213|M.smegmatis_MC2_155 TMTDRELRDQLMTLLVAGHETTATGLSWTLERLIRHPAVLDKAVAAARTT
Mflv_1104|M.gilvum_PYR-GCK SMSRQDIGDELLTLLAAGHETTAATLGWVFERISRHPDVLARLQAEADTD
MAV_5160|M.avium_104 AMSHKEIGDELLTLLAAGHETTASTLAWAFERISRHPELLARLVEEADNG
MUL_3402|M.ulcerans_Agy99 RFSDQDIVNHMIFLMMAAHDTSTSTATTMAYHLAAHPEWQQRCRDESDRL
MLBr_02088|M.leprae_Br4923 QLTEEEIIATCGLLLVAGHETTVNLIANAVLAMLRNPSQWKALSSNPQ--
:: :: : *.*:*:. : :* .
TH_0136|M.thermoresistible__bu GAQR------GAGPYTEAVINETLRLRPPGPVTGR-TTAGHYRLGDYTLA
Mvan_0675|M.vanbaalenii_PYR-1 DTG-----------YTEAVIAETLRLRPAAPITGR-MTTGPYRLGDYTLE
Mb3710c|M.bovis_AF2122/97 GEA-----------FTTAVINETLRVRPPAPLTAR-VAAQPLTIGGYRVE
Rv3685c|M.tuberculosis_H37Rv GEA-----------FTTAVINETLRVRPPAPLTAR-VAAQPLTIGGYRVE
MMAR_5175|M.marinum_M TET-----------FTTAVINETLRVRPPAPFTAR-VAARPFRLGGYLID
MAB_4693|M.abscessus_ATCC_1997 AAGDP-----AGDEYLDAVVKETLRIRPVIFSSGR-VLKESVEVGGYQLP
MSMEG_1213|M.smegmatis_MC2_155 DG--------SGEAYLDAVVRESLRIRPVVFEAGR-VLTEPVELGGYLLP
Mflv_1104|M.gilvum_PYR-GCK GN-----------EYRQAVILETQRVRTVIDFAGRHVYAPTFELGEWIIP
MAV_5160|M.avium_104 GN-----------ELRQAAILEVQRARTVIDFAGRHVYPDVYRLGEWVIP
MUL_3402|M.ulcerans_Agy99 GDGPLDIEALEKLESLDLVMNESIRLVTPVQWAMR-QTVRDTELLGYYLP
MLBr_02088|M.leprae_Br4923 --------------RAPLVVEETLRYDPAIHLIGR-VAAKDMTIGQTTLT
.: * * . * : :
TH_0136|M.thermoresistible__bu PRTRIVLLLGVINRDPNSYPDPHDFRPDRFLHTR----PDPYAWVPFGGG
Mvan_0675|M.vanbaalenii_PYR-1 PDTRIVLLLDVINRNPDTYPQPDEFRPERFLGSR----PHPYAWIPFGGG
Mb3710c|M.bovis_AF2122/97 AGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTR----PQTYAWVPFGGG
Rv3685c|M.tuberculosis_H37Rv AGTRIVVHIIAINRSAEVYEHPHEFRPERFLGTR----PQTYAWVPFGGG
MMAR_5175|M.marinum_M PGTRIVVHMIAINRNPDVYEQPNRFRPERFLGTR----PQTYAWVPFGGG
MAB_4693|M.abscessus_ATCC_1997 VGIMVDPAIGLVHASGAVYPDPARFDPDRMVGTT----LSPTTWLPFGGG
MSMEG_1213|M.smegmatis_MC2_155 AGTLVAPSIGLVHASADVYPDPDRFEPDRMLAST----QAPSTWLPFGGG
Mflv_1104|M.gilvum_PYR-GCK QGYSIVVAIGQVHHREQDYLDPEDFDPQRFVGQR----PSTLSHIPFGGG
MAV_5160|M.avium_104 RGYSIIVGIAQIHDNPDVFPDPRRFDPQRFIDNK----PSALSWIPFGGG
MUL_3402|M.ulcerans_Agy99 KGTNVIAYPGMNHRLPEFWTDPMTFDPDRFAEPRNEHKRHRYAFTPFGGG
MLBr_02088|M.leprae_Br4923 EGDTMVLLLAAANRDPAVYSRPDEFDPDRPSSRH----------LAFAVG
: : : * * *:* .*. *
TH_0136|M.thermoresistible__bu VKRCLGAAFAMRELTTILRILLTEADLRPVNARPESAAGRAAAVVVPRHG
Mvan_0675|M.vanbaalenii_PYR-1 VKRCIGAAFAMRELTTTLHTVLREGELEPVSARPETPPLRAAPVLVPRDG
Mb3710c|M.bovis_AF2122/97 VKRCLGANFSMRELITVLHVLLREGEFTAVDDEPE-RIVRRSIMLVPRRG
Rv3685c|M.tuberculosis_H37Rv VKRCLGANFSMRELITVLHVLLREGEFTAVDDEPE-RIVRRSIMLVPRRG
MMAR_5175|M.marinum_M AKRCLGAAFSMRELVTVLHVLLREGQFTAVDEAPE-RIVRRSIMLAPRHG
MAB_4693|M.abscessus_ATCC_1997 NRRCLGATFAMVEIRVVLREILRRVELNTTTAPDE-KQQAKHVTFVPHRG
MSMEG_1213|M.smegmatis_MC2_155 NRRCLGATFALVEMRVVLREILHRVDLFATTARGE-KQRLKHVTMIPHRG
Mflv_1104|M.gilvum_PYR-GCK TRRCVGAVFANVEMDIVLRTVFRHFTIETTTAPGE-KMHSRGVAYTPDDG
MAV_5160|M.avium_104 TRRCVGAAFANMEMDVVLRTVLRHFTIETTDAPDE-PWHCRGVAFTPKHG
MUL_3402|M.ulcerans_Agy99 AHKCLGMVFGQLEIKTILHRLLRRYRLELARPDYR-ACWDYGGMPVPKDG
MLBr_02088|M.leprae_Br4923 SHFCLGAALARLEATVTLSAISARFPQVQLAGELV---YKPNVAMRGMSA
: *:* :. * * : . .
TH_0136|M.thermoresistible__bu TPVYFRPTAPAASPRCAGRTSTV-----------
Mvan_0675|M.vanbaalenii_PYR-1 TRVRFTPARPAASPRCADRTSTV-----------
Mb3710c|M.bovis_AF2122/97 TRVRFRPAR-------------------------
Rv3685c|M.tuberculosis_H37Rv TRVRFRPAR-------------------------
MMAR_5175|M.marinum_M TRVRFRPRLQESV---------------------
MAB_4693|M.abscessus_ATCC_1997 GSISVRAIRTCAPAVTPTCPADVHGTGQARDPQR
MSMEG_1213|M.smegmatis_MC2_155 GRICVRALRDVAPAP-MTCPAEARRA--------
Mflv_1104|M.gilvum_PYR-GCK GRVVMRRR--------------------------
MAV_5160|M.avium_104 GRIVVHRR--------------------------
MUL_3402|M.ulcerans_Agy99 MPIVLRPL--------------------------
MLBr_02088|M.leprae_Br4923 LPVQV-----------------------------
: .