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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0016 | - | - | 100% (451) | dimethylaniline monooxygenase |
M. thermoresistible (build 8) | TH_0014 | - | e-171 | 65.61% (442) | dimethylaniline monooxygenase |
M. thermoresistible (build 8) | TH_4273 | - | 6e-24 | 28.87% (336) | PUTATIVE FAD dependent oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0916 | - | 3e-21 | 31.80% (217) | monooxygenase |
M. gilvum PYR-GCK | Mflv_4373 | - | 0.0 | 86.14% (433) | flavin-containing monooxygenase |
M. tuberculosis H37Rv | Rv0892 | - | 3e-21 | 31.80% (217) | monooxygenase |
M. leprae Br4923 | MLBr_00065 | - | 1e-10 | 23.23% (409) | putative monooxygenase |
M. abscessus ATCC 19977 | MAB_2607 | - | 0.0 | 72.54% (437) | putative flavin-containing monooxygenase |
M. marinum M | MMAR_3138 | - | 4e-21 | 23.54% (412) | monooxygenase |
M. avium 104 | MAV_3915 | - | 1e-22 | 26.59% (361) | flavin-containing monooxygenase FMO |
M. smegmatis MC2 155 | MSMEG_2202 | - | 0.0 | 85.13% (437) | dimethylaniline monooxygenase |
M. ulcerans Agy99 | MUL_1880 | - | 6e-21 | 25.07% (359) | monooxygenase |
M. vanbaalenii PYR-1 | Mvan_1971 | - | 0.0 | 84.39% (442) | dimethylaniline monooxygenase (N-oxide-forming) |
CLUSTAL 2.0.9 multiple sequence alignment Mb0916|M.bovis_AF2122/97 ------------MTGRCPT-------------VAVVGAGMSGMCVAITLL Rv0892|M.tuberculosis_H37Rv ------------MTGRCPT-------------VAVVGAGMSGMCVAITLL MAV_3915|M.avium_104 -----MTDVVT-HTETAPTPAAKAAKP-VHTRAVIIGTGFSGLGMAIALQ MUL_1880|M.ulcerans_Agy99 -----MTDVVIPSTETTASGEPQAPTPPVKTRAVIIGTGFSGLGMAIALQ MMAR_3138|M.marinum_M MGSESGQ----------------------HYEIVIVGAGFSGIGTAISLL Mflv_4373|M.gilvum_PYR-GCK -------------------------MLQTPPYVAVIGAGISGLTAGKMLK Mvan_1971|M.vanbaalenii_PYR-1 -------------------------MDQTHPRVAVIGAGISGLTAGKMLK MSMEG_2202|M.smegmatis_MC2_155 -------------------------MTPALPRTAIIGAGISGLTAGKMLK TH_0016|M.thermoresistible__bu -------------------------VKRRYPRTAVIGAGISGLTAGKMLK MAB_2607|M.abscessus_ATCC_1997 ---------------------------MTGPSTAIIGAGISGLTSVKMLS MLBr_00065|M.leprae_Br4923 ---------------------MVVMAETEYLDVVIVGAGISGVSAAWHLQ .::*:*:**: * Mb0916|M.bovis_AF2122/97 SAGIT-DVCIYEKADDVGGTWRD-------NTYPGLTCDVPSRLYQYSFA Rv0892|M.tuberculosis_H37Rv SAGIT-DVCIYEKADDVGGTWRD-------NTYPGLTCDVPSRLYQYSFA MAV_3915|M.avium_104 KQGV--GFVILEKADDIGGTWRD-------NSYPGCACDIPSHLYSFSFE MUL_1880|M.ulcerans_Agy99 KQGV--DFVILEKSDDVGGTWRD-------NSYPGCACDIPSHLYSFSFE MMAR_3138|M.marinum_M KAGFA-DFLIVDDADGVGGTWHW-------NTYPGIAVDIPSYSYQFSYE Mflv_4373|M.gilvum_PYR-GCK DYGI--DYTTFESSDRIGGNWAFGNPNGHSSAYRSLHIDTSKDRLSFKDF Mvan_1971|M.vanbaalenii_PYR-1 DYGV--SYTTFETSDRIGGNWAFGNPNGHSSAYRSLHIDTSKDRLSFKDF MSMEG_2202|M.smegmatis_MC2_155 DYRV--PYTTFETSDRIGGNWAFGNPNGHSSAYRSLHIDTSKHRLSFKDF TH_0016|M.thermoresistible__bu DYGV--PYTTFELSDRIGGNWAFGNPNGHSSAYRSLHIDTSKHRLSFKDF MAB_2607|M.abscessus_ATCC_1997 DYGI--PHTCFETSDRIGGNWAFGNPNGHSSAYRSLHIDTSRHQLSFRDF MLBr_00065|M.leprae_Br4923 DRCPNKSYVILEKRAGMGGTWDL-------FRYPGIRSDSDMYTLGFRFR . : :**.* * . * : Mb0916|M.bovis_AF2122/97 KNPNWTQMFSRGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDDG--RW Rv0892|M.tuberculosis_H37Rv KNPNWTQMFSRGGEIQDYLRGIAERYGLRHRIRFGATVVSARFDDG--RW MAV_3915|M.avium_104 PKPDWKNPFSYQPEIWDYLKGVTEKYGLRRYIEFNSLVDRAHWDDDEHRW MUL_1880|M.ulcerans_Agy99 PKPDWRNPFSYQPEIWDYLKGVTEKYGLRRYVEFNSLVDRAYWDDEECRW MMAR_3138|M.marinum_M MRTSWSRTYAHGDELKAYAERCVEKYGLQNYIRFNTTVDEACFDEGAALW Mflv_4373|M.gilvum_PYR-GCK PMPEHYPSFPHHAQIKAYLDDYADTFGLLDHIEFENGVVHAGRTDDG-GW Mvan_1971|M.vanbaalenii_PYR-1 PMPEHYPSFPHHSQVKAYLDEYAEVFGLLEHIEFGNGVVHAAKDGSG-GW MSMEG_2202|M.smegmatis_MC2_155 PMPEHYPSFPHHTQIKEYLDAYADAFGLLDHIEFGNGVVHAERGAHG-GW TH_0016|M.thermoresistible__bu PMPEHYPAFPHHSEIKAYLDSYAEAFGLLDNIEFNNGVVHARLDDGG-GW MAB_2607|M.abscessus_ATCC_1997 PMPDSYPHFPHHTLIKQYLEDYARAFDLKRNIEFQNGIVHAEHRPGG-GW MLBr_00065|M.leprae_Br4923 PWT-KCQAIADGKPILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRW . . : * . ..: :.: : * * Mb0916|M.bovis_AF2122/97 VLRTDSG---TESTVDFLISATGVLHHPR--IPPIAGLDDFRGTVFHSAR Rv0892|M.tuberculosis_H37Rv VLRTDSG---TESTVDFLISATGVLHHPR--IPPIAGLDDFRGTVFHSAR MAV_3915|M.avium_104 HVFTTDG---REYVAQFLISGAGALHIPS--LPDIEGRDEFAGPAFHSAE MUL_1880|M.ulcerans_Agy99 HVFTSDG---REYVAQFLISGAGALHIPS--SPEIEGREEFAGPAFHSAE MMAR_3138|M.marinum_M RLSCSSG---QNLTARFVINCSGVLSRPK--WPDIPGVRDFAGVTLHTAR Mflv_4373|M.gilvum_PYR-GCK IIRDQGG---ADRHFDLLVVANGHHWDPR--LPEFPG--SFDGESIHSHA Mvan_1971|M.vanbaalenii_PYR-1 RILDQAG---AQRHFDLLVVANGHHWDPR--LPQFPG--SFAGESIHSHS MSMEG_2202|M.smegmatis_MC2_155 VIEDQAS---ARRDFDLLVVANGHHWDPR--MPDFPG--EFTGEQIHSHH TH_0016|M.thermoresistible__bu LIEDQSG---ATREFDLLVVGNGHHWDPR--YPDFPG--TFTGETIHSHH MAB_2607|M.abscessus_ATCC_1997 ELLTQAG---ERRLFDLLVVANGHHWDPR--YPDFPG--TFTGTALHSHH MLBr_00065|M.leprae_Br4923 TVQVENNGTPRMISCSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQH : . ::. * * : * * * :*. Mb0916|M.bovis_AF2122/97 WDH---TVPLLGRRIAVIGTGSTGVQLVCGLAGVAG--KVTMFQRTAQWV Rv0892|M.tuberculosis_H37Rv WDH---TVPLLGRRIAVIGTGSTGVQLVCGLAGVAG--KVTMFQRTAQWV MAV_3915|M.avium_104 WDH---TVDLTGKRVAVIGTGASAIQIVPEIVGQVA--ELQLYQRTPPWV MUL_1880|M.ulcerans_Agy99 WDH---SVDLTGKRVAIIGAGASAIQIVPEIVEQVG--ELQLYQRTPPWV MMAR_3138|M.marinum_M WDH---TKDLTGKRVAVIGTGASAVQLIPEVAKIAS--SLTVFQRTPIYC Mflv_4373|M.gilvum_PYR-GCK YIDPATPLELTGKRILVVGIGNSAADITVELSSKALRNQVTLSTRSSAWI Mvan_1971|M.vanbaalenii_PYR-1 YVDPSTPLDLSGKRILVVGIGNSAADITVELSSKALRNDVTLSTRSSAWI MSMEG_2202|M.smegmatis_MC2_155 YIDPRTPLDLTGKRILVVGIGNSAADITVELSSRTLQNQVTLSTRSSAWI TH_0016|M.thermoresistible__bu YIDPATPLDLTGKRILVVGLGNSAADITVELSSRALRNKVTLSTRSSAWI MAB_2607|M.abscessus_ATCC_1997 YIDPRTPLDLMDKRILVVGLGNSAADIAVELSSRATGNTVTLSTRSGAWI MLBr_00065|M.leprae_Br4923 WPE---DLDYAAKNIVVIGSGATAVTLVPALANSGAK-HVTMLQRSPTYI : . :.: ::* * :. : : : : *: : Mb0916|M.bovis_AF2122/97 LPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSFET---FAVALSNPGLH Rv0892|M.tuberculosis_H37Rv LPWPNPRYSKLARVFHRAFPCLGSLAYKAYSLSFET---FAVALSNPGLH MAV_3915|M.avium_104 VPRSNPEIPPAVRAAMENVPGLRALVRLAIYWGQEA---LAFGMTKRPNL MUL_1880|M.ulcerans_Agy99 VPRSNPEIPPALRRAMENVPGLRALARLGIYWAQEA---LAFGMTKRPNV MMAR_3138|M.marinum_M LPKPDFSIPSWAATVMRLVPGAQLMTRTASQAFVEFTFPIAAHFHSLIPV Mflv_4373|M.gilvum_PYR-GCK VPKYIAGRP--GDTLFRTSPHLPLSWQRKAVQLIAP-------------- Mvan_1971|M.vanbaalenii_PYR-1 VPKYIAGRP--GDTFWRTSPYLPLSWQRKAVQLVAP-------------- MSMEG_2202|M.smegmatis_MC2_155 VPKYLAGQP--GDKFFRTTPYLPLSWQRKAVQMIAP-------------- TH_0016|M.thermoresistible__bu VPKYIAGQP--GDKLWRTTPYLPLSWQRKAMQLVAP-------------- MAB_2607|M.abscessus_ATCC_1997 VPKYVAGQP--ADKYFRTSPHLPMSWQRKLFQMMQP-------------- MLBr_00065|M.leprae_Br4923 VSQP--AKDKIAARLNRWLPDKYAYTAVRWKNILRQS---ALYGACQKWP :. . * Mb0916|M.bovis_AF2122/97 RKLVGAVCRASLRR-VRDPRLRRALTPDYEPMCKRLVMS--GGFYRAIQR Rv0892|M.tuberculosis_H37Rv RKLVGAVCRASLRR-VRDPRLRRALTPDYEPMCKRLVMS--GGFYRAIQR MAV_3915|M.avium_104 LKVIEAYAKYNIRRSVKDKELRRKLTPHYRIGCKRILNS--STYYGAVAD MUL_1880|M.ulcerans_Agy99 LKVGEAYAKYNIRRSVKDRELRRKLTPHYRIGCKRILNS--SSYYPAVAN MMAR_3138|M.marinum_M SDLMEEAAKRYMRRAVDDPVTRDQLIPRYSLGCKRPSFH--NSYLATYNR Mflv_4373|M.gilvum_PYR-GCK -------------MLGTDPTMYGLPPADHKLFEAHPTQS--VELPLRLGS Mvan_1971|M.vanbaalenii_PYR-1 -------------MLGTDPTMYGLPPADHKLFEAHPTQS--VELPLRLGS MSMEG_2202|M.smegmatis_MC2_155 -------------MLGTDPTAYGLPAPNHKLFEAHPTQS--VELPLRLGS TH_0016|M.thermoresistible__bu -------------LLGTDPTMYGLPPANHKLFEAHPTQS--VELPLRLGS MAB_2607|M.abscessus_ATCC_1997 -------------LMSGRPDQLGLPMPNHKFGEAHFTQS--VELPLRLGS MLBr_00065|M.leprae_Br4923 QRMRNILLGHVARRLPKGYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRK . : : Mb0916|M.bovis_AF2122/97 DDVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLATGFDSHAF--FRPMQL Rv0892|M.tuberculosis_H37Rv DDVELVTAGIDHVEHRGIVTDDGVLHEVDVIVLATGFDSHAF--FRPMQL MAV_3915|M.avium_104 PKTELVTDHIARITPDGIVTADGTHRPVDVIVYATGFHVTDS--YTYVQI MUL_1880|M.ulcerans_Agy99 PKTRLITDRIARITRNGIVTADGVEHQADVIVYATGFHVTDS--YTYVQI MMAR_3138|M.marinum_M RNVSLETSGITHVDHASVHTEDGKSYPIDVMVLATGFKVMESGNMPTYVL Mflv_4373|M.gilvum_PYR-GCK GDVTPKPN-VARLDGSTVHFVDGTHSDFDVIIYATGYNITFP-FFDPDFV Mvan_1971|M.vanbaalenii_PYR-1 GDVTPKPN-VARLDGHTVHFVDGTSADFDVIIYATGYNITFP-FFDPEFI MSMEG_2202|M.smegmatis_MC2_155 GDVTPKPN-VARLSGDTVLFEDGTSDVFDVIIYATGYNITFP-FFDRDFI TH_0016|M.thermoresistible__bu GDVIPKPN-VSRLDGATVHFEDGTSDDFDAIIYATGYNITFP-FFDPDFI MAB_2607|M.abscessus_ATCC_1997 GDIVPKPD-ISRFDGHTVHFEDGTSTDVDVIIFATGYNITFP-FFDPEFL MLBr_00065|M.leprae_Br4923 GTVDMVTDAIDRFTSTGIRLKSGNELRADIIVTATGLNLQLFG-GAVATV . : :. : .* * :: *** . : Mb0916|M.bovis_AF2122/97 TGRDGIRIDDVWQ-DGPHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVA Rv0892|M.tuberculosis_H37Rv TGRDGIRIDDVWQ-DGPHAHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVA MAV_3915|M.avium_104 KGLHGEDLVDRWNREGIGAHRGITVADVPNLFFLLGPNTGLGHNSVVFMI MUL_1880|M.ulcerans_Agy99 KGQHGEDLVDRWNREGIGAHRGIAVADVPNLFFLLGPNTGLGHNSVVFMI MMAR_3138|M.marinum_M KGRGGVEQSAWWDEHRLQAFEGVSVPGFPNHFNIFGPYG-YNGSSYFTLI Mflv_4373|M.gilvum_PYR-GCK SAPD----------NAIRLYKRMFIPGIENLVFMG---FAQAVPTLFPFV Mvan_1971|M.vanbaalenii_PYR-1 SAPD----------NSIRLYKRMFKPGVDDLVFIG---FAQSVPTLFPFV MSMEG_2202|M.smegmatis_MC2_155 SAPD----------NQIRLYKRMFKPGIDDLVFIG---FAQAIPTLFPFV TH_0016|M.thermoresistible__bu SAPD----------NHIRLYKRMFKPGVENLVFIG---FAQAVPTLFPFV MAB_2607|M.abscessus_ATCC_1997 SAPD----------NRIDLYKRMFKPGLDDLIFVG---LAQAVPSLFPFV MLBr_00065|M.leprae_Br4923 DGQP-------VDLAQTMSYKGMMLSGLPNMIYTVGYTNASWTLKADLVS . .. : ... : . . Mb0916|M.bovis_AF2122/97 ESQAEHIVQWIK-RWRHGEFDTMEPKSAAT--EAYN-TVLRAAMPNTVWT Rv0892|M.tuberculosis_H37Rv ESQAEHIVQWIK-RWRHGEFDTMEPKSAAT--EAYN-TVLRAAMPNTVWT MAV_3915|M.avium_104 ESQIRYVADAIA-TCDKLGAQALAPTRAAQ--DRFN-DELQRRLGPSVWN MUL_1880|M.ulcerans_Agy99 ESQIHYVADAIA-KCDKRGAQALAPTRAAQ--DRFN-EELQRRLAGSVWN MMAR_3138|M.marinum_M EAQSRHIVRCLR-RARTLKADYVEVRQQAN--DRYFGDMVSRRHRQVFWQ Mflv_4373|M.gilvum_PYR-GCK ESQSRLLAAYAVGRYALPPVDEMERTIDAD--QQLHAGHCTDRPR----- Mvan_1971|M.vanbaalenii_PYR-1 ECQSRLLAAYAVGRYALPSADEMERTIDAD--QQLHAGHCTDRPR----- MSMEG_2202|M.smegmatis_MC2_155 ECQSRLLAAYAVGRYALPSTDEMERVIDAD--QRLHAGHCTDRPR----- TH_0016|M.thermoresistible__bu ECQSRLMAAYAVGRYALPPVDEMERVIDAD--QQLHAGHCIDRPR----- MAB_2607|M.abscessus_ATCC_1997 ECQARLVGAYAAGKYRLPPVDEMRAVIEAE--HRKYTGHMLDRPR----- MLBr_00065|M.leprae_Br4923 EFFCRLLNYMNANDFDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQ * . : : Mb0916|M.bovis_AF2122/97 TG---CDSWYLNKDG-IPEVWPFAPAKHRAMLANLHPEEYDLRRYAAVRA Rv0892|M.tuberculosis_H37Rv TG---CDSWYLNKDG-IPEVWPFAPAKHRAMLANLHPEEYDLRRYAAVRA MAV_3915|M.avium_104 SGG--CSSWYLDEHGKNTVLWGGYTWEYWRATRAVKPEEYQFYGIGSRAG MUL_1880|M.ulcerans_Agy99 SGG--CSSWYLDEHGRNTVLWCGYTWQYWLATRSVKPEEYQFFKAGAKSS MMAR_3138|M.marinum_M PSCSNANSYYFDKHG-DVPLRPSTTLETYWRSRTFRLSDYRFERRAESVG Mflv_4373|M.gilvum_PYR-GCK ----------------HTQQVDYFVYEHDLRTRELPAGLKRAQRAVAVAR Mvan_1971|M.vanbaalenii_PYR-1 ----------------HTQQVDYFVYEHDLLKREIPAGRKRAQRVAAVAR MSMEG_2202|M.smegmatis_MC2_155 ----------------HTQQVDYFYYEHDIRAREMPAGAKRAERRAAGTR TH_0016|M.thermoresistible__bu ----------------HTQQVDYFYYEHDLRTRELPAGLKRAGHTAPRRT MAB_2607|M.abscessus_ATCC_1997 ----------------HTQQLDYFLYEHDMRTKELPRGLARAGGVA---- MLBr_00065|M.leprae_Br4923 GSR------------TPWRLNQNYLRDIRLIRRGKVADEGLLFAKKTTPV . Mb0916|M.bovis_AF2122/97 TSRPQSA- Rv0892|M.tuberculosis_H37Rv TSRPQSA- MAV_3915|M.avium_104 V------- MUL_1880|M.ulcerans_Agy99 VNG----- MMAR_3138|M.marinum_M AR------ Mflv_4373|M.gilvum_PYR-GCK -------- Mvan_1971|M.vanbaalenii_PYR-1 -------- MSMEG_2202|M.smegmatis_MC2_155 TAIVGSVA TH_0016|M.thermoresistible__bu PVAL---- MAB_2607|M.abscessus_ATCC_1997 -------- MLBr_00065|M.leprae_Br4923 TV------