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GSESGQHYEIVIVGAGFSGIGTAISLLKAGFADFLIVDDADGVGGTWHWNTYPGIAVDIPSYSYQFSYEM RTSWSRTYAHGDELKAYAERCVEKYGLQNYIRFNTTVDEACFDEGAALWRLSCSSGQNLTARFVINCSGV LSRPKWPDIPGVRDFAGVTLHTARWDHTKDLTGKRVAVIGTGASAVQLIPEVAKIASSLTVFQRTPIYCL PKPDFSIPSWAATVMRLVPGAQLMTRTASQAFVEFTFPIAAHFHSLIPVSDLMEEAAKRYMRRAVDDPVT RDQLIPRYSLGCKRPSFHNSYLATYNRRNVSLETSGITHVDHASVHTEDGKSYPIDVMVLATGFKVMESG NMPTYVLKGRGGVEQSAWWDEHRLQAFEGVSVPGFPNHFNIFGPYGYNGSSYFTLIEAQSRHIVRCLRRA RTLKADYVEVRQQANDRYFGDMVSRRHRQVFWQPSCSNANSYYFDKHGDVPLRPSTTLETYWRSRTFRLS DYRFERRAESVGAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3138 | - | - | 100% (505) | monooxygenase |
| M. marinum M | MMAR_2207 | - | e-180 | 60.94% (489) | monoxygenase |
| M. marinum M | MMAR_3139 | - | 7e-81 | 37.55% (466) | monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1428c | - | 0.0 | 62.55% (486) | monoxygenase |
| M. gilvum PYR-GCK | Mflv_4607 | - | 0.0 | 69.59% (490) | cyclohexanone monooxygenase |
| M. tuberculosis H37Rv | Rv1393c | - | 0.0 | 62.55% (486) | monoxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 1e-24 | 23.18% (440) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_2075 | - | 1e-151 | 83.39% (295) | putative monooxygenase |
| M. avium 104 | MAV_3378 | - | 0.0 | 61.41% (495) | lipolytic enzyme |
| M. smegmatis MC2 155 | MSMEG_0816 | - | 1e-108 | 40.90% (489) | flavin-binding monooxygenase |
| M. thermoresistible (build 8) | TH_4080 | - | 4e-83 | 35.32% (487) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1793 | - | 1e-177 | 60.49% (486) | monoxygenase |
| M. vanbaalenii PYR-1 | Mvan_2671 | - | 1e-175 | 59.43% (493) | cyclohexanone monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3138|M.marinum_M ---------------MGSESGQHYEIVIVGAGFSGIGTAISLL-KAGFAD
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4607|M.gilvum_PYR-GCK MSVHVAGDENAPTSGAPTYEVPTHEILVIGAGFSGIGVGIKLL-KEGFSD
Mb1428c|M.bovis_AF2122/97 -------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSD
Rv1393c|M.tuberculosis_H37Rv -------------------MMPDYHALIVGAGFSGIGAAIKLD-RAGFSD
MUL_1793|M.ulcerans_Agy99 --------------------------MIVGAGFSGIGAAISLD-KAGFGD
MAV_3378|M.avium_104 ---------------MSSPAVPDHHTLIIGAGFSGIGAAIKLD-KAGLPD
Mvan_2671|M.vanbaalenii_PYR-1 --------------------MHDVETVIVGAGFSGIGAAIGLD-RVGMSD
MSMEG_0816|M.smegmatis_MC2_155 ------------------MRPVVHDAVIVGAGFAGLGAAIQLK-KMSFDD
TH_4080|M.thermoresistible__bu -MTVTEPSADITPANTPTQPPVRTRALIVGTGFSGLGMAIALQ-RRG-ID
MLBr_00065|M.leprae_Br4923 --------------MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKS
MMAR_3138|M.marinum_M FLIVDDADGVGGTWHWNTYPGIAVDIPSYSYQFSYEMRTSWSRTYAHGDE
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4607|M.gilvum_PYR-GCK FLIVDEAQGVGGTWYWNTYPGIAVDIPSYSYQFSFEKRPSWSRTYAPGIE
Mb1428c|M.bovis_AF2122/97 YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
Rv1393c|M.tuberculosis_H37Rv YLVVEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGHE
MUL_1793|M.ulcerans_Agy99 YLVIEAGDAVGGTWFWNTYPGIAVDIPSFSYQFSFEQSPDWSRSYAPGRE
MAV_3378|M.avium_104 YRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRE
Mvan_2671|M.vanbaalenii_PYR-1 YVVVEAGDEPGGTWYWNTYPGIAVDIPSFSYQFSFEQSSAWSRTYAHGHE
MSMEG_0816|M.smegmatis_MC2_155 FVILEREDDLGGTWYVNHYPGLAVDVPTTTYSYFFEPNPSWSRLFSTGRE
TH_4080|M.thermoresistible__bu FLMLEKADDIGGTWRDNTYPGCACDIPSHLYSFSFEPKADWRHLFSYQDE
MLBr_00065|M.leprae_Br4923 YVILEKRAGMGGTWDLFRYPGIRSDSDMYTLGFRFRP-WTKCQAIADGKP
MMAR_3138|M.marinum_M LKAYAERCVEKYGLQNYIRFNTTVDEACFDEGAALWRLSCSSGQ---NLT
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4607|M.gilvum_PYR-GCK LKNYAKHCVKKYGLASRIRFGVTVVRAEFDEESTLWRLFTSTDE---ELT
Mb1428c|M.bovis_AF2122/97 LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
Rv1393c|M.tuberculosis_H37Rv LKAYAEHCVDKYGIRSRIRLNTKVLAAEFDDEHSLWRVQTDPGG---EIT
MUL_1793|M.ulcerans_Agy99 LRAYAEHCADKYGIRPRIRFNTKVLGAELDDERSLWRLQTDPGG---DLI
MAV_3378|M.avium_104 LKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGG---EVT
Mvan_2671|M.vanbaalenii_PYR-1 LKTYAEHCVDKYGLRPRIRFATTVRSADFDEAQGIWRLALDTADGPATLS
MSMEG_0816|M.smegmatis_MC2_155 IKRYADDVADKYDVRRHIRFGTTVTGARWDEDDNVWQVSLTDGE---QLQ
TH_4080|M.thermoresistible__bu IQEYLQGVTAKYGLRRYIHFDSLVDRAHWDDTEHRWHVFTADGR---EYI
MLBr_00065|M.leprae_Br4923 ILEYIKSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMIS
MMAR_3138|M.marinum_M ARFVINCSGVLSRPK--WPDIPGVRDFAGVTLHTARWDHTKDLTGKRVAV
MAB_2075|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4607|M.gilvum_PYR-GCK ARFVINASGVLTRPK--SPDIPGVGDFGGVTMHTSRWDHQQTLTGKRVAV
Mb1428c|M.bovis_AF2122/97 ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
Rv1393c|M.tuberculosis_H37Rv ARFLISACGILTVPK--LPDIDGVDSFEGVTMHTARWDHTQDLTGKRVGI
MUL_1793|M.ulcerans_Agy99 TRFIINASGVLTVPK--LPDIAGVDSFAGVTMHTARWDHSQELTGKRVGI
MAV_3378|M.avium_104 ARFLISACGVLTVPN--LPDIDGVDSFAGITMHTARWDHGQDLRGKRVAV
Mvan_2671|M.vanbaalenii_PYR-1 ARFLVNAGGVLTVPK--LPDIAGVDSFAGVTMHTARWDHTQDLRGKRVAI
MSMEG_0816|M.smegmatis_MC2_155 ARFLITATGFLSQPH--TPDIPGITEFDGKVIHTTDWDDGCSLYGRRAAV
TH_4080|M.thermoresistible__bu AQFLISCAGALHIPS--IPDFPGRDQFAGPAFHSAQWDHSVDLTGKRVAV
MLBr_00065|M.leprae_Br4923 CSFLFLCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPEDLDYAAKNIVV
MMAR_3138|M.marinum_M IGTGASAVQLIPEVAKI-ASSLTVFQRTPIYCLPKPDFSIPSWAATVMRL
MAB_2075|M.abscessus_ATCC_1997 --------------------------------MPKPDIPIPTWAGRLLHF
Mflv_4607|M.gilvum_PYR-GCK IGTGASAVQLIPSIAKD-VDTLTVFQRTPIWCLPKFDFAVPRPLSALLRL
Mb1428c|M.bovis_AF2122/97 IGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-
Rv1393c|M.tuberculosis_H37Rv IGTGASAVQVIPEMAPI-VSHLTVFQRTPIWCFPKFDVPLPTAVRWAMR-
MUL_1793|M.ulcerans_Agy99 IGTGASAVQVIPEIAPI-VKHLTVFQRTPIWCFPKFDFPLPAALRWAMR-
MAV_3378|M.avium_104 IGTGASAVQVIPEIAPI-VSSLTVFQRTPIWCFPKLDVPLPAPARWAMR-
Mvan_2671|M.vanbaalenii_PYR-1 IGTGASAVQVIPEIAPI-VERLTVFQRTPIWCFPKFDVPLSKTAQTMMR-
MSMEG_0816|M.smegmatis_MC2_155 VGTGATAVQLIPELAER-VAELTVYQRTPIWVVPKVDVRFPPAVRALFAR
TH_4080|M.thermoresistible__bu IGTGASAIQIVPEIIDR-VAQLQLYQRTPAWVVPRTNDELPAWLRRALEN
MLBr_00065|M.leprae_Br4923 IGSGATAVTLVPALANSGAKHVTMLQRSPTYIVSQPAKDKIAARLNRWLP
..:
MMAR_3138|M.marinum_M VPGAQLMTRTASQAFVEFTFPIAAHFHSLIP-VSDLMEEAAKRYMRRAVD
MAB_2075|M.abscessus_ATCC_1997 LPGAQLATRTASQAFVEITFPIAAHFHTVIP-FADVMESAAKRYMRREVH
Mflv_4607|M.gilvum_PYR-GCK APGAQIAARGASQAFVELTFPVAAHFHTAIP-LASAIERAAISYMRRQVT
Mb1428c|M.bovis_AF2122/97 IPGGKAVHRLLSQAFVEATFPIAAHYFAVFP-LAKHMESAGRRYLRQQVH
Rv1393c|M.tuberculosis_H37Rv IPGGKAVHRLLSQAFVEATFPIAAHYFAVFP-LAKHMESAGRRYLRQQVH
MUL_1793|M.ulcerans_Agy99 IPGGKALQRLLSQAYVEATFPISAHYFTVFP-LARWSAVLGRRYLRQRVD
MAV_3378|M.avium_104 FPGGKALQRLLSQAYVELTFPISAHYFTVIP-LAKRMAALGRAYLRRQVR
Mvan_2671|M.vanbaalenii_PYR-1 LPFGKSLQRLISQAFVELTFPLAAQYFTVNP-MAKRMGAVGRAYLRKQVD
MSMEG_0816|M.smegmatis_MC2_155 VPLTQRVVRAITDAIYAFMVDTAVLKHRYFRRLNIAAADLGRLHLAASIR
TH_4080|M.thermoresistible__bu IPGLRLALRGGIYALQEALAVGMTKYPGMLR----IGHLLGKWNINRSVK
MLBr_00065|M.leprae_Br4923 DKYAYTAVRWKNILRQSALYGACQKWPQRMR--NILLGHVARRLPKGYDV
* .
MMAR_3138|M.marinum_M DPVTRDQLIPRYSLGCKRPSFHNSYLATYNRRNVSLETSGITHVDHASVH
MAB_2075|M.abscessus_ATCC_1997 DPTTREQLIPRYSLGCKRPSFHNSYLATYNRSNVSLETSGITHIDHASVH
Mflv_4607|M.gilvum_PYR-GCK DPVVREKLTPRYALGCKRPSFHNEYLKTFNRENVLLETNPITRVDETAVI
Mb1428c|M.bovis_AF2122/97 DPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVA
Rv1393c|M.tuberculosis_H37Rv DPVVREQLTPRYAVGCKRPGFHNTYLSTFNRDNVRLVTEPIDKITPTAVA
MUL_1793|M.ulcerans_Agy99 DPVVRDQLTPRYAVDCKRPGFHNGYLSTFNRDNVQLVTEPIEKITPTSVA
MAV_3378|M.avium_104 DPAVREQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEPIDKITPDAVA
Mvan_2671|M.vanbaalenii_PYR-1 DPVLRDKLTPRYAVGCKRPGFHNTYLSTFNRDNVDLVTEPIDKITGSGVS
MSMEG_0816|M.smegmatis_MC2_155 DPDLRSKLTPDYDFGCKRPTFSNSYYRTFTKPHVHLQADGIDHVEPDGIV
TH_4080|M.thermoresistible__bu DPQLRAKLTPDYRLGCKRILNSSTYYPAVADPRTEVITESIDRITTDGIV
MLBr_00065|M.leprae_Br4923 QKHFGPHYNPWEQRLCLVP--DGDLFRAIRKGTVDMVTDAIDRFTSTGIR
: : * * . : . : :. * :. .:
MMAR_3138|M.marinum_M TEDGKSYPIDVMVLATGFKVMES----GNMPTYVLKGRGGVEQSAWWDEH
MAB_2075|M.abscessus_ATCC_1997 SRDGKAHPIDVLILATGFKVMES----GNMPTYVLKGRGGLEQATWWDEH
Mflv_4607|M.gilvum_PYR-GCK TADGVRHEIDVLVLATGFKVMES----DSMPTYSLRGVAGRDQAQWWDEN
Mb1428c|M.bovis_AF2122/97 TTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGASLSRFWDEH
Rv1393c|M.tuberculosis_H37Rv TTDGASHEIDVLVLATGFKVLDT----DSIPTYAVTGTGGASLSRFWDEH
MUL_1793|M.ulcerans_Agy99 TDDGTDHEIDVLILATGFKVLDT----DDVLTYPVIGRAGRSLSQFWEEH
MAV_3378|M.avium_104 TTDGETHEIDVLILATGFKVMDP----DSVPTFAVTGSGGRSLSRFWDEH
Mvan_2671|M.vanbaalenii_PYR-1 TTDGSLHEVDVLILATGFKVFAAHDGDDSVATFPVTGPGGRSLARFWDDN
MSMEG_0816|M.smegmatis_MC2_155 NADGSKTVIDTLVLATGFDLWEA-----NFPAIEVIGRQGRDLGKWWRET
TH_4080|M.thermoresistible__bu TSDGTERAVDVIVYATGFHVSDS------YKYVQIKGLNGEDIVDRFNRE
MLBr_00065|M.leprae_Br4923 LKSGNELRADIIVTATGLNLQLFG------------GAVATVDGQPVDLA
.* * :: ***:.: * .
MMAR_3138|M.marinum_M RLQAFEGVSVPGFPNHFNIFGPYGYNGS-SYFTLIEAQSRHIVRCLRRAR
MAB_2075|M.abscessus_ATCC_1997 RLQAFEGVSVPGFPNHFNIFGPYGYNGS-SYFTLIEAQSRHIVRCLRRAR
Mflv_4607|M.gilvum_PYR-GCK RLQAYEGVSVPGFPNHFSVFGPYGYNGS-SYFALIEAQAGHILRCLRHAR
Mb1428c|M.bovis_AF2122/97 RLQAYEGVSVPGYPNFFTVFGPYGYVGS-SYFALIETQAHHIIRCLKRAR
Rv1393c|M.tuberculosis_H37Rv RLQAYEGVSVPGYPNFFTVFGPYGYVGS-SYFALIETQAHHIIRCLKRAR
MUL_1793|M.ulcerans_Agy99 RAQAYQGVSVPGYRNFFAVFGPYGYVGS-SYFALIETQTHHILRCLKRAR
MAV_3378|M.avium_104 RLQAYEGVTVPGFPNLFTVFGPYGYVGS-SYFALIEAQTHHIVRCLKRAQ
Mvan_2671|M.vanbaalenii_PYR-1 RLQAYEGVSVPGFPNFFTVFGPYGYVGS-SYFALIEAQTRHIVRCLDAAR
MSMEG_0816|M.smegmatis_MC2_155 RFQAYQGVSMPYFPNYLSLAGPYAFLGL-NFFNTMEYQMRLMERLLGEVA
TH_4080|M.thermoresistible__bu GPMAHRGTAVADLPNAYLLLGPNTGLGHNSMVYMIESQINYVIEAIKAVD
MLBr_00065|M.leprae_Br4923 QTMSYKGMMLSGLPNMIYTVG-YTNASWTLKADLVSEFFCRLLNYMNAND
:..* :. * * . :. : . :
MMAR_3138|M.marinum_M TLKADYVEVRQQANDRYFGDMVSRRHRQVFWQPSCSNANSYYFDKHGDVP
MAB_2075|M.abscessus_ATCC_1997 ALGANLVEVKKEANDRYFAEVLSRRHRQVFWQPSCSGANSYYFDKHGDVP
Mflv_4607|M.gilvum_PYR-GCK TADSNYVEVREEANQRFFAEMLARRHTQVFWQDSCAGANSYYFDKHGDVP
Mb1428c|M.bovis_AF2122/97 RTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVP
Rv1393c|M.tuberculosis_H37Rv RTGATRIEVTEEANARYFAEVMRRRHRQVFWQDSCRLANSYYFDKNGDVP
MUL_1793|M.ulcerans_Agy99 RDGATRVEVTEEANARYFAEMMRRRYRQVFWQDSCRRANSYYFDKNGDVP
MAV_3378|M.avium_104 RLGATRVEVSEEANDRYFAEMMRRRHRQIFWQDSCRLANSYYFDKNGDVP
Mvan_2671|M.vanbaalenii_PYR-1 RRRATRVEVRREANDRYFAEMMRKRHRQIFWQDSCQLSNSYYFDQHGDVP
MSMEG_0816|M.smegmatis_MC2_155 RRDARTFEVTEEANRRYLDRMTDALGDSLFTLGNCASARSYYFNPSGEAT
TH_4080|M.thermoresistible__bu KAGAQALAPTREAQDRYNAELQARLGRSVWNTGGCR---SWYLDEHGNNR
MLBr_00065|M.leprae_Br4923 FDTVAVEYPGSDVEERPFMDFTPGYVLRSLDALPKQGSRTPWRLNQNYLR
:.: * . : : .
MMAR_3138|M.marinum_M -LRPSTTLETYWRSRTFRLSDYRFERR----AESVGAR-----
MAB_2075|M.abscessus_ATCC_1997 -LRPSTTFETYWRSRTFRLSDYQFENR----AEVVGAR-----
Mflv_4607|M.gilvum_PYR-GCK -LRPTTTVESIWRSRRFDLADYRFERRPAKKADTAPQKVDTAG
Mb1428c|M.bovis_AF2122/97 -LRPTTTVEAYWRSRRFDLGDYRISS-----------------
Rv1393c|M.tuberculosis_H37Rv -LRPTTTVEAYWRSRRFDLGDYRISS-----------------
MUL_1793|M.ulcerans_Agy99 -LRPTTTVEAYWRGRHFDLDDYRFGR-----------------
MAV_3378|M.avium_104 -LRPGTTPEVYWRSRRFDLDDYRFTG-----------------
Mvan_2671|M.vanbaalenii_PYR-1 -LRPASTPEAYWRSRRFPIDDYEFSC-----------------
MSMEG_0816|M.smegmatis_MC2_155 LLRPMTTRRAVAEASRFPLSDYTFA------------------
TH_4080|M.thermoresistible__bu VLWGGFTWQYRLATRTLDPAEYRFWG-----------------
MLBr_00065|M.leprae_Br4923 DIRLIRRGKVADEGLLFAKKTTPVTV-----------------
: . : .