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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4273 | - | - | 100% (388) | FAD dependent oxidoreductase |
| M. thermoresistible (build 8) | TH_0014 | - | 7e-28 | 28.61% (381) | dimethylaniline monooxygenase |
| M. thermoresistible (build 8) | TH_0016 | - | 5e-24 | 28.87% (336) | dimethylaniline monooxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0916 | - | 2e-17 | 31.84% (201) | monooxygenase |
| M. gilvum PYR-GCK | Mflv_3867 | - | 7e-84 | 46.53% (346) | FAD dependent oxidoreductase |
| M. tuberculosis H37Rv | Rv0892 | - | 2e-17 | 31.84% (201) | monooxygenase |
| M. leprae Br4923 | MLBr_00065 | - | 6e-11 | 21.26% (381) | putative monooxygenase |
| M. abscessus ATCC 19977 | MAB_2607 | - | 3e-23 | 28.92% (332) | putative flavin-containing monooxygenase |
| M. marinum M | MMAR_0403 | - | 6e-19 | 26.97% (356) | monooxygenase |
| M. avium 104 | MAV_2172 | - | 4e-18 | 29.12% (182) | FAD dependent oxidoreductase, putative |
| M. smegmatis MC2 155 | MSMEG_2038 | - | 5e-23 | 29.31% (348) | monooxygenase, flavin-binding family protein |
| M. ulcerans Agy99 | MUL_1053 | - | 1e-18 | 26.40% (356) | monooxygenase |
| M. vanbaalenii PYR-1 | Mvan_1971 | - | 3e-24 | 28.66% (335) | dimethylaniline monooxygenase (N-oxide-forming) |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0916|M.bovis_AF2122/97 ------MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKADDVGG
Rv0892|M.tuberculosis_H37Rv ------MTGRCPTVAVVGAGMSGMCVAITLLSAG-ITDVCIYEKADDVGG
MMAR_0403|M.marinum_M ------MTS-PLSVGIIGAGPGGLALGILLKNRG-FENFTIFDRESDVGG
MUL_1053|M.ulcerans_Agy99 ------MTS-PLSVGIIGAGPGGLALGILLKNRG-FENFNIFDRESDVGG
MAV_2172|M.avium_104 ------MVTDRFDAIIVGAGFGGIGAAIQLKRLG-FDNIVILDREDDLGG
MLBr_00065|M.leprae_Br4923 --MVVMAETEYLDVVIVGAGISGVSAAWHLQDRCPNKSYVILEKRAGMGG
MSMEG_2038|M.smegmatis_MC2_155 MGATESDDPAYTDVLIIGAGISGINAAYRIHEKCPGLTYTLLERRERIGG
TH_4273|M.thermoresistible__bu --------MNDHQVAVIGAGPSGVAAAVSLRDR--GIRPLLIDRAEHVGA
Mflv_3867|M.gilvum_PYR-GCK -------------MVVLGAGPAGLGIARELKHRH-GVDPLIVDRSDAPAA
MAB_2607|M.abscessus_ATCC_1997 --------MTGPSTAIIGAGISGLTSVKMLSDY--GIPHTCFETSDRIGG
Mvan_1971|M.vanbaalenii_PYR-1 ------MDQTHPRVAVIGAGISGLTAGKMLKDY--GVSYTTFETSDRIGG
::*** .*: : : ..
Mb0916|M.bovis_AF2122/97 TWRDN-------TYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYL
Rv0892|M.tuberculosis_H37Rv TWRDN-------TYPGLTCDVPSRLYQYSFAKNPNWTQMFSRGGEIQDYL
MMAR_0403|M.marinum_M TWRIN-------TYPGLACDVKSHLYSYSFDLNPGWSRLWSGQPEILAYF
MUL_1053|M.ulcerans_Agy99 TWRIN-------TYPGLACDVKSHLYSYSFDLNPGWSGLWSGQPEILAYF
MAV_2172|M.avium_104 TWHVN-------HYPGIAVDIPSTTYSYWFEPNPGWSRLFAPGGEVKQYA
MLBr_00065|M.leprae_Br4923 TWDLF-------RYPGIRSDSDMYTLGFRFRPWT-KCQAIADGKPILEYI
MSMEG_2038|M.smegmatis_MC2_155 TWDLF-------RYPGIRSDSDIFTLSYPYEPWT-RPENVADGGDIRAYL
TH_4273|M.thermoresistible__bu SWRAR--------YDRLRLNTGRLTSHLPNRPYPAGTAVFPTRDQVVAHL
Mflv_3867|M.gilvum_PYR-GCK SWRAR--------YDGFRLNTCGFWSHLPGQRIPLSFGRWPTRDQMVEYF
MAB_2607|M.abscessus_ATCC_1997 NWAFGNPNGHSSAYRSLHIDTSRHQLSFRDFPMPDSYPHFPHHTLIKQYL
Mvan_1971|M.vanbaalenii_PYR-1 NWAFGNPNGHSSAYRSLHIDTSKDRLSFKDFPMPEHYPSFPHHSQVKAYL
.* * : : . . : :
Mb0916|M.bovis_AF2122/97 RGIAERYGLRHRIRFGATVVSARFD--DGRWVLRTDSGTE---STVDFLI
Rv0892|M.tuberculosis_H37Rv RGIAERYGLRHRIRFGATVVSARFD--DGRWVLRTDSGTE---STVDFLI
MMAR_0403|M.marinum_M QRCADRYGLRPHLRLSTEIRSARWESQTRQWTLSTADGEQ---HQFSVVV
MUL_1053|M.ulcerans_Agy99 QRCADRYELRPHLRLGTEIRSARWESQTRQWTLSTADGEQ---HQFSVVV
MAV_2172|M.avium_104 ADVADKYDVRRHMRFNTTVEGAQWDEDAEVWRVALAGGES---LTTRFLI
MLBr_00065|M.leprae_Br4923 KSTAVMHGIDKYIRLNHKVTGADWSSIENRWTVQVENNGTPRMISCSFLF
MSMEG_2038|M.smegmatis_MC2_155 TETARKYGIDRHIRFNTHVLSADWDSATDTWTLHTEQDGQPRDYRARFVF
TH_4273|M.thermoresistible__bu DRHAREDGIDLLLGTT---VARVDRD-GEGWRLWTSGGD----VCARHVV
Mflv_3867|M.gilvum_PYR-GCK DDYVRRQGLRLRLGVR---AERIDRD-GAGWSITTDDED----VRASAVV
MAB_2607|M.abscessus_ATCC_1997 EDYARAFDLKRNIEFQNGIVHAEHRP-GGGWELLTQAGER---RLFDLLV
Mvan_1971|M.vanbaalenii_PYR-1 DEYAEVFGLLEHIEFGNGVVHAAKDG-SGGWRILDQAGAQ---RHFDLLV
. : : * : :.
Mb0916|M.bovis_AF2122/97 SATGVLH--HPRIPPIAGLDDFRGTVFHSARWDHT---VPLLGRRIAVIG
Rv0892|M.tuberculosis_H37Rv SATGVLH--HPRIPPIAGLDDFRGTVFHSARWDHT---VPLLGRRIAVIG
MMAR_0403|M.marinum_M SAVGIFS--RPAYPDLVEQQRFTGTVMHSSRWDHS---VPLAGARIAVLG
MUL_1053|M.ulcerans_Agy99 SVVGIFS--RPAYPDLVEQQRFTGTVMHSSRWDHS---VPLAGARIAVLG
MAV_2172|M.avium_104 TATGFLS--QPHTPDIPGIGSFGGKVVHTTAWDHD---YRYQGRRIAVIG
MLBr_00065|M.leprae_Br4923 LCSGYYNYEQGYAPTFLGSEDFTGPIIHPQHWPED---LDYAAKNIVVIG
MSMEG_2038|M.smegmatis_MC2_155 FGTGYYNYDEPYTPDFPGINDFRGEVVHPQFWPES---LDHTGKRVVVIG
TH_4273|M.thermoresistible__bu VATGYEH--TPNIPDWPGADGFTGRLLHSSAYRN---PIPFSGLRVLVVG
Mflv_3867|M.gilvum_PYR-GCK VALGNHN--TPGLPPWPGMDGFTGQLLHAADYRS---AEPFGGQEVLVVG
MAB_2607|M.abscessus_ATCC_1997 VANGHHW--DPRYPDFPGT--FTGTALHSHHYIDPRTPLDLMDKRILVVG
Mvan_1971|M.vanbaalenii_PYR-1 VANGHHW--DPRLPQFPGS--FAGESIHSHSYVDPSTPLDLSGKRILVVG
* * * * .*. : .: *:*
Mb0916|M.bovis_AF2122/97 TGSTGVQLVCGLAGV-AGKVTMFQ-RTAQWVLPWPNPRYSKLARVFHRAF
Rv0892|M.tuberculosis_H37Rv TGSTGVQLVCGLAGV-AGKVTMFQ-RTAQWVLPWPNPRYSKLARVFHRAF
MMAR_0403|M.marinum_M TGSTAAQLVPELAKV-ADRVYSIQ-RSPTWILPKPDRPYSRWERWVFAHV
MUL_1053|M.ulcerans_Agy99 TGSTAAQLVPELAKV-ADRVYSIQ-RSPTWILPKPDRPYSRWERWVFAHV
MAV_2172|M.avium_104 TGASAVQVVPELAKE-AEELTVYQ-RTATHVLPKVDFEFDPAVRRLFARV
MLBr_00065|M.leprae_Br4923 SGATAVTLVPALANSGAKHVTMLQ-RSPTYIVSQPAKDKIAARLNRWLPD
MSMEG_2038|M.smegmatis_MC2_155 SGATAISLVPAMART-AGHVTMLQ-RSPTYMMSSPRINPAVQAIRKVLPR
TH_4273|M.thermoresistible__bu AGSSAMEIVHDVAT-GGAAQAWLAVRTPPNIMLRALPGGFPSDYLATPLF
Mflv_3867|M.gilvum_PYR-GCK SGNSAVDIALQLSS-AVAAKVWMSVRTPPQLVPRSTAG-LPIDTLGPLLA
MAB_2607|M.abscessus_ATCC_1997 LGNSAADIAVELSSRATGNTVTLSTRSGAWIVPKYVAG-QPADKYFRTSP
Mvan_1971|M.vanbaalenii_PYR-1 IGNSAADITVELSSKALRNDVTLSTRSSAWIVPKYIAG-RPGDTFWRTSP
* :. :. :: *: ::
Mb0916|M.bovis_AF2122/97 PCLGSLAYKAYSLSFET-FAVALSNPGLHR-----KLVGAVCRASLRRVR
Rv0892|M.tuberculosis_H37Rv PCLGSLAYKAYSLSFET-FAVALSNPGLHR-----KLVGAVCRASLRRVR
MMAR_0403|M.marinum_M PFAARLYRTRLWLRSESNISVIEHGSPKTK-----EFTELALRMLENTVS
MUL_1053|M.ulcerans_Agy99 PFAARLYRTRLWLRSESNISVIEHGSPKTK-----EFTELALRMLENTVS
MAV_2172|M.avium_104 PAAQRALRWVTDVLLEIIMIVGALHFKESRGRGNISASDLAKINRFRWIR
MLBr_00065|M.leprae_Br4923 KYAYTAVRWKNILRQSALYGACQKWPQRMR-------NILLGHVARRLPK
MSMEG_2038|M.smegmatis_MC2_155 RVAHQVVRVRNAMVQYVAYHLFRAAPRLGR-------WVIRKATISVLPK
TH_4273|M.thermoresistible__bu DAPVGLVDRMARLAQRATIGDLSE-------------------------Y
Mflv_3867|M.gilvum_PYR-GCK TLPVWLLDGAAAAMRRVWFGELAG-------------------------V
MAB_2607|M.abscessus_ATCC_1997 HLPMSWQRKLFQMMQPLMSGRPDQ-------------------------L
Mvan_1971|M.vanbaalenii_PYR-1 YLPLSWQRKAVQLVAPMLGTDPTM-------------------------Y
Mb0916|M.bovis_AF2122/97 DPRLRRALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVEHRG
Rv0892|M.tuberculosis_H37Rv DPRLRRALTPDYEPMCKRLVMS--GGFYRAIQRDDVELVTAGIDHVEHRG
MMAR_0403|M.marinum_M DPQLRRQLTPDHPMGCKRLVFS--SEFLTALARPNVELVTSPARYLRQRS
MUL_1053|M.ulcerans_Agy99 DPQLRRQLTPDHPMGCKRLVFS--SEFLTALTRPNVELVTSPARYLRQRS
MAV_2172|M.avium_104 DKELRAKLTPDYDCGCKRPTFS--NSFYRVLTQPNVHLETNPIERIEPDG
MLBr_00065|M.leprae_Br4923 GYDVQKHFGPHYNPWEQRLCLVPDGDLFRAIRKGTVDMVTDAIDRFTSTG
MSMEG_2038|M.smegmatis_MC2_155 GYPVDVHFKPRYNPWDQRMCLVLDKDIFEGISSGRFDVVTDHIDHFDADG
TH_4273|M.thermoresistible__bu GLPTPREGVFARGKRLGRAPVIVDREVVDAIRARRFEVVRT-IGRFDGGT
Mflv_3867|M.gilvum_PYR-GCK GLPPPRQGIYTALRAQAKVPTIAD-ELVPRVKDGRIEIVSA-VESFETNR
MAB_2607|M.abscessus_ATCC_1997 GLPMPN-------HKFGEAHFTQSVELPLRLGSGDIVPKPD-ISRFDGHT
Mvan_1971|M.vanbaalenii_PYR-1 GLPPAD-------HKLFEAHPTQSVELPLRLGSGDVTPKPN-VARLDGHT
. . . : . .
Mb0916|M.bovis_AF2122/97 IVTDDGVLHEVDVIVLATGFDSHAF-FRPMQLTGRDGIRIDDVWQDG-PH
Rv0892|M.tuberculosis_H37Rv IVTDDGVLHEVDVIVLATGFDSHAF-FRPMQLTGRDGIRIDDVWQDG-PH
MMAR_0403|M.marinum_M LVTADGAEYDVDVVVCATGYAAADY-LGQLEVLGEDGAGLHEVWRDG-AH
MUL_1053|M.ulcerans_Agy99 LVTADGAEYDVDVVVCATGYAAADY-LGQLEVLGEDGAGLHEVWRDG-AH
MAV_2172|M.avium_104 IVTADGRKNVIDTLVLATGFDLWEANFPAIEVIGRKGRNLGKWWRETRFQ
MLBr_00065|M.leprae_Br4923 IRLKSGNELRADIIVTATGLNLQLFGGAVATVDGQP-------VDLAQTM
MSMEG_2038|M.smegmatis_MC2_155 IVLTSGNRIDADIVVTATGLQLQALGGITLRVDGDE-------VKPTERF
TH_4273|M.thermoresistible__bu VVLTDGRRLQPDAVICATGYSRGLEPLVGHLGVLDDR-----------GL
Mflv_3867|M.gilvum_PYR-GCK VVLADGTALAPQVVIGATGYRRGLDALVGHLGVLTDD-----------GH
MAB_2607|M.abscessus_ATCC_1997 VHFEDGTSTDVDVIIFATGYNITFPFFDPEFLSAPDN-----------RI
Mvan_1971|M.vanbaalenii_PYR-1 VHFVDGTSADFDVIIYATGYNITFPFFDPEFISAPDN-----------SI
: .* : :: ***
Mb0916|M.bovis_AF2122/97 AHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGE
Rv0892|M.tuberculosis_H37Rv AHQTVAIPGFPNFFMMLGPHSPVGNFPLTAVAESQAEHIVQWIKRWRHGE
MMAR_0403|M.marinum_M AYLGMAVPGFPNFFMLYGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKS
MUL_1053|M.ulcerans_Agy99 AYLGMAVPGFPNFFMLCGPNTNVGSNSVIFMLEAQARYIVAALAHLRRKS
MAV_2172|M.avium_104 AYQGVSMPYFPNYLSLASPFAFSG-LSFFHTIEYQMRHMDRLLGEVKRRG
MLBr_00065|M.leprae_Br4923 SYKGMMLSGLPNMIYTVG----YTNASWTLKADLVSEFFCRLLNYMNAND
MSMEG_2038|M.smegmatis_MC2_155 VYKEFLLEDVPNMAWCIG----YTNASWTLRADMTAKAVAKLLAYMGSHG
TH_4273|M.thermoresistible__bu PRSAGEVAAALG-LWFIG---------FQS-RPGLISFAAKQSQRIAKRI
Mflv_3867|M.gilvum_PYR-GCK PVVNGPPAAAPG-LWFAG---------YEEPLIGPLRAFRRHAPDVAE-V
MAB_2607|M.abscessus_ATCC_1997 DLYKRMFKPGLDDLIFVG---------LAQAVPSLFPFVECQARLVGAYA
Mvan_1971|M.vanbaalenii_PYR-1 RLYKRMFKPGVDDLVFIG---------FAQSVPTLFPFVECQSRLLAAYA
. .
Mb0916|M.bovis_AF2122/97 FDTMEPKSAATEAYNTVLRAAMPNTVWTTG----CDSWYLNKDG-IPEVW
Rv0892|M.tuberculosis_H37Rv FDTMEPKSAATEAYNTVLRAAMPNTVWTTG----CDSWYLNKDG-IPEVW
MMAR_0403|M.marinum_M KTYIAVRPGVLAEFMAKVDRWMTGTVWTTE----CSNYFRAPNGRVVTQW
MUL_1053|M.ulcerans_Agy99 KTYIAVRPGVLAEFIAKVDRWMTGTVWTTE----CSNYFRAPNGRVVTQW
MAV_2172|M.avium_104 ATTFEVTEEANDRFMERMTKLLDNSVFYAGNCATSRSYYFSPSGEASLLR
MLBr_00065|M.leprae_Br4923 FDTVAVEYPGSDVEERPFMDFTPGYVLRSL------DALPKQGSRTPWRL
MSMEG_2038|M.smegmatis_MC2_155 YTHAYPHKGSTPIAEKRTWDLEAGYIQRSE------HALPRSGTKRPWHV
TH_4273|M.thermoresistible__bu AAELVAAPAITPVADGG---------------------------------
Mflv_3867|M.gilvum_PYR-GCK VSHLAASSAASQTLSR----------------------------------
MAB_2607|M.abscessus_ATCC_1997 AGKYRLPPVDEMRAVIEAEHRKYTGHMLDR---------PRHTQQLDYFL
Mvan_1971|M.vanbaalenii_PYR-1 VGRYALPSADEMERTIDADQQLHAGHCTDR---------PRHTQQVDYFV
Mb0916|M.bovis_AF2122/97 PFAPAKHRAMLANLHPEEYDLRRYAAVRATSRPQSA--------------
Rv0892|M.tuberculosis_H37Rv PFAPAKHRAMLANLHPEEYDLRRYAAVRATSRPQSA--------------
MMAR_0403|M.marinum_M PRSARSFWGMTRRFKPADFSFQPAAVFAADGGDRNAGQR-----------
MUL_1053|M.ulcerans_Agy99 PRSARSFWGMTRRFKPADFSFQPAAVFAADGGDRNAGQRWPNPRPSIGWT
MAV_2172|M.avium_104 PTSTLNSIREASSFPLSDYVIA----------------------------
MLBr_00065|M.leprae_Br4923 NQNYLRDIRLIRRGKVADEGLLFAKKTTPVTV------------------
MSMEG_2038|M.smegmatis_MC2_155 RHNYLLDA-IDHRFDRIDESMVFGRAPAAVQVPASAPSPAPPSAPRAGAS
TH_4273|M.thermoresistible__bu --------------------------------------------------
Mflv_3867|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2607|M.abscessus_ATCC_1997 YEHDMRTKELPRGLARAGGVA-----------------------------
Mvan_1971|M.vanbaalenii_PYR-1 YEHDLLKREIPAGRKRAQRVAAVAR-------------------------
Mb0916|M.bovis_AF2122/97 ------------------
Rv0892|M.tuberculosis_H37Rv ------------------
MMAR_0403|M.marinum_M ------------------
MUL_1053|M.ulcerans_Agy99 PCCAPSRRRESTSPRSRS
MAV_2172|M.avium_104 ------------------
MLBr_00065|M.leprae_Br4923 ------------------
MSMEG_2038|M.smegmatis_MC2_155 AVEPAAS-----------
TH_4273|M.thermoresistible__bu ------------------
Mflv_3867|M.gilvum_PYR-GCK ------------------
MAB_2607|M.abscessus_ATCC_1997 ------------------
Mvan_1971|M.vanbaalenii_PYR-1 ------------------