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SAPDSITVTVADHNGVAVLSIGGEIDLITAAALEEAIGEVVADNPTALVIDLSAVEFLGSVGLKILAATS EKIGQSVKFGVVARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3687c | rsfB | - | 100% (122) | ANTI-ANTI-SIGMA FACTOR RSFB (ANTI-SIGMA FACTOR ANTAGONIST) (REGULATOR OF SIGMA F B) |
| M. tuberculosis H37Rv | Rv1365c | rsfA | 7e-06 | 23.21% (112) | anti-anti-sigma factor RSFA (anti-sigma factor antagonist) |
| M. tuberculosis H37Rv | Rv1904 | - | 2e-05 | 27.84% (97) | hypothetical protein Rv1904 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3712c | - | 2e-40 | 100.00% (81) | hypothetical protein Mb3712c |
| M. gilvum PYR-GCK | Mflv_3284 | - | 6e-17 | 42.11% (95) | anti-sigma-factor antagonist |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5181 | - | 2e-47 | 76.23% (122) | anti-anti-sigma regulatory factor |
| M. avium 104 | MAV_0435 | - | 8e-41 | 72.97% (111) | anti-anti-sigma factor |
| M. smegmatis MC2 155 | MSMEG_6127 | - | 6e-19 | 38.05% (113) | anti-anti-sigma factor |
| M. thermoresistible (build 8) | TH_1832 | - | 1e-24 | 53.47% (101) | ANTI-ANTI-SIGMA FACTOR RSFB (ANTI-SIGMA FACTOR ANTAGONIST) |
| M. ulcerans Agy99 | MUL_4427 | - | 2e-06 | 25.41% (122) | hypothetical protein MUL_4427 |
| M. vanbaalenii PYR-1 | Mvan_4702 | - | 8e-19 | 42.72% (103) | anti-sigma-factor antagonist |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3687c|M.tuberculosis_H37Rv ----------MSAPDSITVTVADH--NGVAVLSIGGEIDLITAAALEEAI
Mb3712c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5181|M.marinum_M ----------MSAPDSITAVVTDH--DGVTVLSIGGEIDLVTAPALEEAI
MAV_0435|M.avium_104 -------------------MVEDH--DGVSVVSVSGEIDLVTAPALEQAI
TH_1832|M.thermoresistible__bu --------------------VEHR--DDSAVLRVQGVVDLATGDALQQAI
Mflv_3284|M.gilvum_PYR-GCK MDEQAAEGTAAGGAPSSTCVVTQRWVDTTAVVAVTGVVDMLTSPQLETAI
MSMEG_6127|M.smegmatis_MC2_155 MTSQD----------PANCTVEERRVGDITVVAVTGTVDMLTAPKLEDAI
Mvan_4702|M.vanbaalenii_PYR-1 -----------------MQQFTEHQIDGVLVVAAVGAVDMLTAPQLQEAI
MUL_4427|M.ulcerans_Agy99 --------MNATAKSPNALAIDTRSEDSLVVLSVEGAIDSTNCAALRDAI
Rv3687c|M.tuberculosis_H37Rv GEVVADNPTALVIDLSAVEFLGSVGLKILAATSEKIGQ--SVKFGVVARG
Mb3712c|M.bovis_AF2122/97 ---MADNPTALVIDLSAVEFLGSVGLKILAATSEKIGQ--SVKFGVVARG
MMAR_5181|M.marinum_M GAVVADSPTALVIDLSGVEFLGSVGLKILAATYEKLGT--AAEFGVVAQG
MAV_0435|M.avium_104 GAVVADSPPALVIDLSAVEFLGSVGLKILAATYEKLGK--ETGFGVVARG
TH_1832|M.thermoresistible__bu DDLIATRPSALVVDLSAVDFLASVGLQILVATHERLSP--SARFAVVADG
Mflv_3284|M.gilvum_PYR-GCK DDALNQKPGAVVIDFTEVEFLASAGMGVLVAAHDKAGS--EVKISVVADG
MSMEG_6127|M.smegmatis_MC2_155 GSAAKSEPSAVVVDLSAVDFLASAGMGVLVAAHGELAP--AVRLVVVADG
Mvan_4702|M.vanbaalenii_PYR-1 NAALDRQPTGVVVDLTAVDFLGSAGMQVLMTTRRQLEG--TVKFAVVADG
MUL_4427|M.ulcerans_Agy99 IKATLDEPSAVVVNVSALQVPDEASWSIFVSARWQVDTPQHVPILLVCAS
* .:*::.: ::. ... :: :: . . : :*. .
Rv3687c|M.tuberculosis_H37Rv SVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR--------------
Mb3712c|M.bovis_AF2122/97 SVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR--------------
MMAR_5181|M.marinum_M PATRRPIHLTGLDKTFPLYPALDDALTGVRDGKLNR--------------
MAV_0435|M.avium_104 PATRRPIHLTGLDKTFPLYPTLDDALTAVRDGKLNG--------------
TH_1832|M.thermoresistible__bu PATSRPIQLTRLDEVIALYPTLDEALSGVRTGERAE--------------
Mflv_3284|M.gilvum_PYR-GCK PATSRPLKLVGIADIVALYSNLDEALAARDT-------------------
MSMEG_6127|M.smegmatis_MC2_155 PATSRPLKLVGIADVVDLFATLDEALSSLKT-------------------
Mvan_4702|M.vanbaalenii_PYR-1 PATSRPLKITGIADYVDLFSTLDVALRNLAG-------------------
MUL_4427|M.ulcerans_Agy99 RAGRELITRTGVTRFMPVYPTEKRAIKAVGRLARRKVRYAQVQLPANLGS
. . : : . ::. . *:
Rv3687c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3712c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5181|M.marinum_M --------------------------------------------------
MAV_0435|M.avium_104 --------------------------------------------------
TH_1832|M.thermoresistible__bu --------------------------------------------------
Mflv_3284|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6127|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4702|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4427|M.ulcerans_Agy99 LRESRKLVREWLTSWSKPGLIPVALVIVNVFVENVLEHTGSDPVIKVQCD
Rv3687c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3712c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_5181|M.marinum_M --------------------------------------------------
MAV_0435|M.avium_104 --------------------------------------------------
TH_1832|M.thermoresistible__bu --------------------------------------------------
Mflv_3284|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6127|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4702|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4427|M.ulcerans_Agy99 GTAATIAVSDGSNAPAIRLQTPPKGIDVSGLAIVEALCRAWGSTPTATGK
Rv3687c|M.tuberculosis_H37Rv ------------
Mb3712c|M.bovis_AF2122/97 ------------
MMAR_5181|M.marinum_M ------------
MAV_0435|M.avium_104 ------------
TH_1832|M.thermoresistible__bu ------------
Mflv_3284|M.gilvum_PYR-GCK ------------
MSMEG_6127|M.smegmatis_MC2_155 ------------
Mvan_4702|M.vanbaalenii_PYR-1 ------------
MUL_4427|M.ulcerans_Agy99 TVWAIIGPENQL