For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_0435 (-)

annotation: anti-anti-sigma factor
coordinates: 428508 - 428849
length: 113

LVEDHDGVSVVSVSGEIDLVTAPALEQAIGAVVADSPPALVIDLSAVEFLGSVGLKILAATYEKLGKETG
FGVVARGPATRRPIHLTGLDKTFPLYPTLDDALTAVRDGKLNG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_0435--100% (113)anti-anti-sigma factor
M. avium 104MAV_5272-1e-2146.53% (101) anti-anti-sigma factor
M. avium 104MAV_1619-2e-0534.67% (75) anti-anti-sigma factor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3712c-2e-2875.00% (80) hypothetical protein Mb3712c
M. gilvum PYR-GCKMflv_2021-6e-2247.96% (98) anti-sigma-factor antagonist
M. tuberculosis H37RvRv3687crsfB6e-4172.97% (111) anti-anti-sigma factor RSFB (anti-sigma factor antagonist)
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_5181-3e-5085.71% (112) anti-anti-sigma regulatory factor
M. smegmatis MC2 155MSMEG_6127-4e-2145.00% (100) anti-anti-sigma factor
M. thermoresistible (build 8)TH_1832-6e-2956.88% (109) ANTI-ANTI-SIGMA FACTOR RSFB (ANTI-SIGMA FACTOR ANTAGONIST)
M. ulcerans Agy99MUL_3602-5e-0834.91% (106) anti sigma factor antagonist
M. vanbaalenii PYR-1Mvan_3003-3e-2146.39% (97) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


MAV_0435|M.avium_104                --------------------MVEDH--DGVSVVSVSGEIDLVTAPALEQA
MMAR_5181|M.marinum_M               -----------MSAPDSITAVVTDH--DGVTVLSIGGEIDLVTAPALEEA
Mb3712c|M.bovis_AF2122/97           --------------------------------------------------
Rv3687c|M.tuberculosis_H37Rv        -----------MSAPDSITVTVADH--NGVAVLSIGGEIDLITAAALEEA
TH_1832|M.thermoresistible__bu      ---------------------VEHR--DDSAVLRVQGVVDLATGDALQQA
MSMEG_6127|M.smegmatis_MC2_155      MTSQ-----------DPANCTVEERRVGDITVVAVTGTVDMLTAPKLEDA
Mvan_3003|M.vanbaalenii_PYR-1       MDEQAAEGTNVGGAASSSTCVVTERWVERTAVVAVSGVVDMLTSPQLESA
Mflv_2021|M.gilvum_PYR-GCK          ------------------MQQFTEREVDGVVIVAAVGAIDMLTAPQLQEA
MUL_3602|M.ulcerans_Agy99           ----------------MDLLAVEHEVRQDTVVVRAKGDVDSSTVEQLVVH
                                                                                      

MAV_0435|M.avium_104                IGAVVADSPPA----LVIDLSAVEFLGSVGLKILAATYEK-LGKETGFGV
MMAR_5181|M.marinum_M               IGAVVADSPTA----LVIDLSGVEFLGSVGLKILAATYEK-LGTAAEFGV
Mb3712c|M.bovis_AF2122/97           ----MADNPTA----LVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
Rv3687c|M.tuberculosis_H37Rv        IGEVVADNPTA----LVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
TH_1832|M.thermoresistible__bu      IDDLIATRPSA----LVVDLSAVDFLASVGLQILVATHER-LSPSARFAV
MSMEG_6127|M.smegmatis_MC2_155      IGSAAKSEPSA----VVVDLSAVDFLASAGMGVLVAAHGE-LAPAVRLVV
Mvan_3003|M.vanbaalenii_PYR-1       IDTALSQQPAA----VVIDFTDVEFLASAGMGVLVAAHDK-AGSDVKISV
Mflv_2021|M.gilvum_PYR-GCK          VAAAARRRPSG----LVVDLTSVDFLGSAGMQVLMETRKG-LDGDTRFAV
MUL_3602|M.ulcerans_Agy99           LAAAMQLAATHPARLVVIDLQPVTFFGSAGLNAVLECHEQGMAAGTSVRL
                                            ..     :*:*:  * *:.*.*:  :           . . :

MAV_0435|M.avium_104                VARGPATRRPIHLTGLDKTFPLYPTLDDALTAVRDGKLNG-------
MMAR_5181|M.marinum_M               VAQGPATRRPIHLTGLDKTFPLYPALDDALTGVRDGKLNR-------
Mb3712c|M.bovis_AF2122/97           VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Rv3687c|M.tuberculosis_H37Rv        VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
TH_1832|M.thermoresistible__bu      VADGPATSRPIQLTRLDEVIALYPTLDEALSGVRTGERAE-------
MSMEG_6127|M.smegmatis_MC2_155      VADGPATSRPLKLVGIADVVDLFATLDEALSSLKT------------
Mvan_3003|M.vanbaalenii_PYR-1       VAEGPATSRPLKLVGIADIVALYPNLEEALAARDT------------
Mflv_2021|M.gilvum_PYR-GCK          VADGPATSRPLKITGITDYVDLYPSLDVALADLAG------------
MUL_3602|M.ulcerans_Agy99           VADHGQLLAPIQVTELDRIFEIYPTLAGALRPGKPGEHDLEDVERPR
                                    **       *:::  :   . ::. *  **