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M. gilvum PYR-GCK Mflv_3284 (-)

annotation: anti-sigma-factor antagonist
coordinates: 3471434 - 3471823
length: 129

DEQAAEGTAAGGAPSSTCVVTQRWVDTTAVVAVTGVVDMLTSPQLETAIDDALNQKPGAVVIDFTEVEFL
ASAGMGVLVAAHDKAGSEVKISVVADGPATSRPLKLVGIADIVALYSNLDEALAARDT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3284--100% (129)anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_2021-4e-2550.96% (104) anti-sigma-factor antagonist
M. gilvum PYR-GCKMflv_4938-1e-1943.48% (115) anti-sigma-factor antagonist

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3712c-2e-1146.27% (67) hypothetical protein Mb3712c
M. tuberculosis H37RvRv3687crsfB6e-1742.11% (95) anti-anti-sigma factor RSFB (anti-sigma factor antagonist)
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0214-1e-2043.64% (110) hypothetical protein MMAR_0214
M. avium 104MAV_5272-5e-2349.06% (106) anti-anti-sigma factor
M. smegmatis MC2 155MSMEG_6127-6e-3361.06% (113) anti-anti-sigma factor
M. thermoresistible (build 8)TH_0498-1e-3464.49% (107) anti-anti-sigma factor
M. ulcerans Agy99MUL_3602-9e-0532.04% (103) anti sigma factor antagonist
M. vanbaalenii PYR-1Mvan_3003-1e-5686.15% (130) anti-sigma-factor antagonist

CLUSTAL 2.0.9 multiple sequence alignment


Mb3712c|M.bovis_AF2122/97           --------------------------------------------------
Rv3687c|M.tuberculosis_H37Rv        MSAP-------------DSITVTVADHNGVAVLSIGGEIDLITAA----A
Mflv_3284|M.gilvum_PYR-GCK          MDEQAAEGTAAGGAP-SSTCVVTQRWVDTTAVVAVTGVVDMLTSP----Q
Mvan_3003|M.vanbaalenii_PYR-1       MDEQAAEGTNVGGAASSSTCVVTERWVERTAVVAVSGVVDMLTSP----Q
TH_0498|M.thermoresistible__bu      --------------------VIDERWDADIAVVSATGVVDMLSAP----Q
MSMEG_6127|M.smegmatis_MC2_155      MTSQDPAN-----------CTVEERRVGDITVVAVTGTVDMLTAP----K
MMAR_0214|M.marinum_M               MVEQSGDPTPP------TAFGIEKSRVGEAVVVTVSGELDMLTAP----R
MAV_5272|M.avium_104                MGEQPGDLADP------TPFEVGKHQVDQAVVLTVSGEVDMLSSP----M
MUL_3602|M.ulcerans_Agy99           ----------------MDLLAVEHEVRQDTVVVRAKGDVDSSTVEQLVVH
                                                                                      

Mb3712c|M.bovis_AF2122/97           --------MADNPTALVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
Rv3687c|M.tuberculosis_H37Rv        LEEAIGEVVADNPTALVIDLSAVEFLGSVGLKILAATSEK-IGQSVKFGV
Mflv_3284|M.gilvum_PYR-GCK          LETAIDDALNQKPGAVVIDFTEVEFLASAGMGVLVAAHDK-AGSEVKISV
Mvan_3003|M.vanbaalenii_PYR-1       LESAIDTALSQQPAAVVIDFTDVEFLASAGMGVLVAAHDK-AGSDVKISV
TH_0498|M.thermoresistible__bu      LDEAIRTALGKKPRALVVDFTAVDFLASAGMGVLVAIHDE-VSPAVNLTI
MSMEG_6127|M.smegmatis_MC2_155      LEDAIGSAAKSEPSAVVVDLSAVDFLASAGMGVLVAAHGE-LAPAVRLVV
MMAR_0214|M.marinum_M               LAEMLRTSLIEAPATLIVDLSKVDFLASAGMTVLVSAKAQ-AVAPTRFVV
MAV_5272|M.avium_104                LAEAVQTALAAKPAALIVDLSKVGFLASAGMTVLVTTQAE-LQPPTKFAV
MUL_3602|M.ulcerans_Agy99           LAAAMQLAATHPARLVVIDLQPVTFFGSAGLNAVLECHEQGMAAGTSVRL
                                                .  :::*:  * *:.*.*:  :     :     . . :

Mb3712c|M.bovis_AF2122/97           VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Rv3687c|M.tuberculosis_H37Rv        VARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR-------
Mflv_3284|M.gilvum_PYR-GCK          VADGPATSRPLKLVGIADIVALYSNLDEALAARDT------------
Mvan_3003|M.vanbaalenii_PYR-1       VAEGPATSRPLKLVGIADIVALYPNLEEALAARDT------------
TH_0498|M.thermoresistible__bu      VADGPATSRPLKLLGIADLVPLHATLDEALAAVAT------------
MSMEG_6127|M.smegmatis_MC2_155      VADGPATSRPLKLVGIADVVDLFATLDEALSSLKT------------
MMAR_0214|M.marinum_M               VADGPATSRPIRLMGIDAMLPLYDALDDALNDISDS-----------
MAV_5272|M.avium_104                VADGSATSRPIKLMGIDSVLSLYPSLNDALSALSGA-----------
MUL_3602|M.ulcerans_Agy99           VADHGQLLAPIQVTELDRIFEIYPTLAGALRPGKPGEHDLEDVERPR
                                    **       *:::  :   . :.  *  **