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M. tuberculosis H37Rv Rv1365c (rsfA)

annotation: ANTI-ANTI-SIGMA FACTOR RSFA (ANTI-SIGMA FACTOR ANTAGONIST) (REGULATOR OF SIGMA F A)
coordinates: 1537783 - 1538169
length: 128

NPTQAGSFTTPVSNALKATIQHHDSAVIIHARGEIDAANEHTWQDLVTKAAAATTAPEPLVVNLNGLDFM
GCCAVAVLAHEAERCRRRGVDVRLVSRDRAVARIIHACGYGDVLPVHPTTESALSAT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1365crsfA-100% (128)ANTI-ANTI-SIGMA FACTOR RSFA (ANTI-SIGMA FACTOR ANTAGONIST) (REGULATOR OF SIGMA F A)
M. tuberculosis H37RvRv2638-6e-3357.66% (111) hypothetical protein Rv2638
M. tuberculosis H37RvRv1904-5e-2948.78% (123) hypothetical protein Rv1904

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1400c-9e-7199.22% (128) hypothetical protein Mb1400c
M. gilvum PYR-GCKMflv_4424-2e-0832.08% (106) anti-sigma-factor antagonist
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2512-2e-0631.25% (96) hypothetical protein MAB_2512
M. marinum MMMAR_2061-7e-2949.56% (113) hypothetical protein MMAR_2061
M. avium 104MAV_3518-1e-3356.64% (113) anti-anti-sigma factor
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_1832-2e-0626.42% (106) ANTI-ANTI-SIGMA FACTOR RSFB (ANTI-SIGMA FACTOR ANTAGONIST)
M. ulcerans Agy99MUL_3282-1e-2849.56% (113) hypothetical protein MUL_3282
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Rv1365c|M.tuberculosis_H37Rv        --------MNP---TQAGSFTTPVSN---ALKATIQHH-DSAVIIHARGE
Mb1400c|M.bovis_AF2122/97           --------MNP---TQAGSFTTPVSN---ALKATIQHH-DSAVIIHARGE
MMAR_2061|M.marinum_M               MSVDIAEPFTP-HPMLSIRLVRELGDPHSTLRATTDFR-SAAVLIHAGGE
MUL_3282|M.ulcerans_Agy99           MSVDIAEPFTP-HPMLSIRLLRELGDPHSTLRAATDFR-STAVLIHAGGE
MAV_3518|M.avium_104                -----MEPMSATHLTLSTKLVYELGDPNSTLRATTARS-GSAVLIYAGGE
Mflv_4424|M.gilvum_PYR-GCK          -----------------------MAERVGLLEIGQEVH-DVAVVVRAGGE
TH_1832|M.thermoresistible__bu      ----------------------------------VEHR-DDSAVLRVQGV
MAB_2512|M.abscessus_ATCC_1997      -MSVIDQNASRFAARAKTGVVSLFSSADDTARFTAHWHRPSAVLVRATGE
                                                                             :.:: . * 

Rv1365c|M.tuberculosis_H37Rv        IDAANEHTWQDLVTKAAAATTAP--EPLVVNLNGLDFMGCCAVAVLAHEA
Mb1400c|M.bovis_AF2122/97           IDAANEHTWQDLVTKAAAATTAP--EPLVVNLNGLDFMGCCAVAVLAHKA
MMAR_2061|M.marinum_M               VDAANEHTWRQLIAETAASAPSP--GLFIVDVSGLDFMGCCAFEVLAEQA
MUL_3282|M.ulcerans_Agy99           VDAANEHTWRQLIAETAASAPSP--GLFVVDVSGLDFMGCCAFEVLAEQA
MAV_3518|M.avium_104                IDACNEDTWRHLVSEAAGVVATP--GPFVVDVTGLEFMGCCAFAVLTDEA
Mflv_4424|M.gilvum_PYR-GCK          VDSGTVETLAAALDSAVAAAAAHPTRTVVVDLDGITYFGSAGLNALLTCR
TH_1832|M.thermoresistible__bu      VDLATGDALQQAIDDLIATRPSA----LVVDLSAVDFLASVGLQILVATH
MAB_2512|M.abscessus_ATCC_1997      IDAVNANHLAEYATRYLDGHRTL-----VLDLQGLRFFGTDGLVALDRVR
                                    :*  . .              :      :::: .: ::.  ..  *    

Rv1365c|M.tuberculosis_H37Rv        ERCRRRGVDVRLVSRDR-AVARIIHACGYGDVLPVHPTTESALSAT----
Mb1400c|M.bovis_AF2122/97           ERCRRRGVDVRLVSRDR-AVARIIHACGYGDVLPVHPTTESALSAT----
MMAR_2061|M.marinum_M               GRCRARGVELRIASAAHTRVTRIVAACGLSDALPVYRSVDAALALPAPSD
MUL_3282|M.ulcerans_Agy99           GRCRARGVELRIASAAHTRVTRIVAACGLSDALPVYRSVDAALALPAPSD
MAV_3518|M.avium_104                KRCRQRGIDLRLVSCEP-IVGRIIDACGLSDILPIYPTVDSALSGADRW-
Mflv_4424|M.gilvum_PYR-GCK          EEGEGRGVVVRLVATTA-EVTRPIEVTRLARILRPYPSVGEAVAAPEDPP
TH_1832|M.thermoresistible__bu      ER-LSPSARFAVVADGP-ATSRPIQLTRLDEVIALYPTLDEALSGVRTGE
MAB_2512|M.abscessus_ATCC_1997      RHCKVQGIDWTVIPGDA--VTKLLTLSGDMAAYPVNDAIPDVWKKLAQ--
                                     .    .    : .     . : :             :   .        

Rv1365c|M.tuberculosis_H37Rv        ----
Mb1400c|M.bovis_AF2122/97           ----
MMAR_2061|M.marinum_M               ----
MUL_3282|M.ulcerans_Agy99           ----
MAV_3518|M.avium_104                ----
Mflv_4424|M.gilvum_PYR-GCK          EDPR
TH_1832|M.thermoresistible__bu      RAE-
MAB_2512|M.abscessus_ATCC_1997      ----