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SFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAAT FHAQFVQTLSAGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGADGTAPGQNGGAGGLLYGNGGN GAAGVNAGIAGGSGGAAGLIGNGGSGGAGGAGAAGGSGGQGGLLYGNGGAGGNGGAATIPGGNGGAGGAG GNAWLFGNGGAGGLGAAGAAGAAGVNPLTVPAGQGSMGNNGEPGGPGQPGTEFGQTGGTGGTGGTGLSVG GTGGTGGTGGTGGAGGSGGRGGLLVGDGGAGGIGGTGGEGGIGARGGTGGQGGMGGAGQPGVGGDAGDGG NGGIGGDGGAGGDGGAGGAGGAGGLFGVSGSSGLGGAAGSGGNGGGGGEPGVAGSPGVGPAGRGGDGNLG QFGPEGAPGQPGQPGQPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3595c | PE_PGRS59 | - | 100% (439) | PE-PGRS FAMILY PROTEIN |
| M. tuberculosis H37Rv | Rv2162c | PE_PGRS38 | e-138 | 55.76% (495) | PE-PGRS family protein |
| M. tuberculosis H37Rv | Rv1091 | PE_PGRS22 | e-138 | 53.06% (539) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3626c | PE_PGRS59 | 1e-149 | 77.25% (356) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-81 | 43.18% (447) | triple helix repeat-containing collagen |
| M. leprae Br4923 | MLBr_01183 | - | 9e-14 | 41.30% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 1e-39 | 35.75% (386) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_5099 | - | 1e-157 | 62.23% (458) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 7e-24 | 41.67% (168) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 1e-66 | 36.96% (460) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 8e-48 | 43.92% (296) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3507 | - | 1e-125 | 54.21% (487) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 5e-85 | 44.62% (455) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VEAASYVADP
MAV_4827|M.avium_104 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAA-------------------------------------LANAGLSAVS
MAV_4827|M.avium_104 ------------------------------------------MNIVLGVS
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
MAB_4284c|M.abscessus_ATCC_199 AAQVGAVMPVVAESVASNYGYQSQWVNTGN----PIHDLSGNLQNYYAAQ
MAV_4827|M.avium_104 MAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGT
Rv3595c|M.tuberculosis_H37Rv MS-FVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSA
Mb3626c|M.bovis_AF2122/97 MS-FVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSA
MLBr_01183|M.leprae_Br4923 MPLFLNAEPQALTAAANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSI
MMAR_5099|M.marinum_M MP-LVFATPEIIAAAATDLAQIGSAISGANTAAAAPTTEVLAAGADEVST
MUL_3507|M.ulcerans_Agy99 MS-FVSVTQEALAAAASDVGVIGSSLQAANMSVAAPTAGVLAAGADEVSV
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGTG
MAB_4284c|M.abscessus_ATCC_199 PDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFN
MAV_4827|M.avium_104 REGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAA
.
Rv3595c|M.tuberculosis_H37Rv AIAALFGAHAQAYQTISAQAATFHAQFVQTLSAGAG--------------
Mb3626c|M.bovis_AF2122/97 AIAALFGAHAQAYQTISAQAATFHAQFVQTLSAGAG--------------
MLBr_01183|M.leprae_Br4923 LLAHFFSGHGRQYQAHASQGATNHQDLIQSLLTSSS--------------
MMAR_5099|M.marinum_M VVASLFSRYAQAYQVLGADMAAIHDQFVQALNAGAN--------------
MUL_3507|M.ulcerans_Agy99 AMAALFSGHGQAYQTLSAQANAFHAQFLQALTNAGG--------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 RGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP----------IASG
MAV_4827|M.avium_104 LAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIP-------------
..
Rv3595c|M.tuberculosis_H37Rv -AYANAEAANV---------------------------------------
Mb3626c|M.bovis_AF2122/97 -AYANAEAANV---------------------------------------
MLBr_01183|M.leprae_Br4923 -AYAGTETAN----------------------------------------
MMAR_5099|M.marinum_M -WYAGVESANSSTLQTV---------------------------------
MUL_3507|M.ulcerans_Agy99 -AYAAAEVANLSPLQGV---------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu NGYRTTDNNALDGGHGG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 QGSTAVNGDVRDSNIIN---------------------------------
MAV_4827|M.avium_104 DVYKQQIRAESYGDAAG---------------------------------
Rv3595c|M.tuberculosis_H37Rv ----------------------------------------QQSLLNAINA
Mb3626c|M.bovis_AF2122/97 ----------------------------------------QQSLLNAINA
MLBr_01183|M.leprae_Br4923 ----------------------------------------HDSL------
MMAR_5099|M.marinum_M ----------------------------------------QQDVLGLINA
MUL_3507|M.ulcerans_Agy99 ----------------------------------------EQGVLGVVNA
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
TH_3810|M.thermoresistible__bu ------------------------------------------NGGNVGFF
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------ADHGSNVGVD
MAV_4827|M.avium_104 ----------------------------------------QLSAMVAGLE
Rv3595c|M.tuberculosis_H37Rv PTQALLGRPLIG---------------DGADGTAPGQNGGAGGLLYGNGG
Mb3626c|M.bovis_AF2122/97 PTQALLGRPLIG---------------DGADGTAPGQNGGAGGLLYGNGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M PTQALLGRGLIG---------------DGAAGTASHPDGYDGGFLYGSGG
MUL_3507|M.ulcerans_Agy99 PAQALLGRPLIG---------------DGAAGTAASPNGGAGGLLYGNGG
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGGQ-
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGGQ-
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
TH_3810|M.thermoresistible__bu SLFNLGG--------------------AGGWGGSGVDG------------
MAB_4284c|M.abscessus_ATCC_199 QSQTRVGGDYTN---------------VSGHGSADIDKSVTVVDDHSQRN
MAV_4827|M.avium_104 KLESLPGGLLLVG------SGVDVAPLKQVLQTTTFLDVSVAEEPETALA
Rv3595c|M.tuberculosis_H37Rv NGAAG--VNAGIAGGSGGAAGLIGNGGSGG--------------------
Mb3626c|M.bovis_AF2122/97 NGAAG--VNAGIAGGSGGAAGLIGNGGSGG--------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M SGYN--SATSGVGGGAGGAAGLIGNGGAGG--------------------
MUL_3507|M.ulcerans_Agy99 AGYSYTSGATAEAGGNGGAAGLIGNGGAGG--------------------
Mflv_5091|M.gilvum_PYR-GCK -GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 -GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
TH_3810|M.thermoresistible__bu ---------VDVVGGNP---------------------------------
MAB_4284c|M.abscessus_ATCC_199 TTNINDSFNTDRSTNIGSGNTTNTEIGSHN--------------------
MAV_4827|M.avium_104 RGAALAAANAPLFASSTAALAYAQDPGTGAVDQYSLP-------------
Rv3595c|M.tuberculosis_H37Rv ---AGGAGAAGGSGGQGG------------------------LLYGNGGA
Mb3626c|M.bovis_AF2122/97 ---AGGAGAAGGSGGQGG------------------------LLYGNGGA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ---AGGAAAAGGSGGQGG------------------------WLYGNGGV
MUL_3507|M.ulcerans_Agy99 ---SGWAGGAGGAGGNGG------------------------WLYGNGGA
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
TH_3810|M.thermoresistible__bu ---------DGGTPG------------------------------AHGES
MAB_4284c|M.abscessus_ATCC_199 -------QANIGTS------------------------------TSAGGS
MAV_4827|M.avium_104 --DYLYVPVDPEPGDDE------------------------LAYSAVGEE
Rv3595c|M.tuberculosis_H37Rv GGNGGAATIPGGNG------------------------------------
Mb3626c|M.bovis_AF2122/97 GGNGGAATIPGGNG------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M GGAGGAASTAGGSG------------------------------------
MUL_3507|M.ulcerans_Agy99 GGLGGAAAGDYTAG------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
TH_3810|M.thermoresistible__bu HTPGVYTDRQ----------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAVGGNAGLAGNAG------------------------------------
MAV_4827|M.avium_104 DAESPTVVIEKLFLP-----------------------------------
Rv3595c|M.tuberculosis_H37Rv ---------------GAGGAGGNAWLFGNGGAGG----------------
Mb3626c|M.bovis_AF2122/97 ---------------GAGGAGGNAWLFGNGGAGG----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ---------------GLGGAGGNAGLWGNGGAGG----------------
MUL_3507|M.ulcerans_Agy99 ---------------GVGGAGGNAGLWGDGGAGGNGSATYDYDQNFSRLG
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST--
TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG---------------
MAB_4284c|M.abscessus_ATCC_199 -------------LAGNAGLAGNAGLAGNAGLAGN---------------
MAV_4827|M.avium_104 ---------------EDSEPRRRPVLLVGSGLAVVG------------IS
Rv3595c|M.tuberculosis_H37Rv ----LGAAGAAG-----------AAGVN---PLTVPAGQGSMGNNG----
Mb3626c|M.bovis_AF2122/97 ----LGAAGAAG-----------AAGVN---PLTVPAGQGSMGNNG----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ----AGGDGTAG-----------AAGVN---PTTMPAGNGTPGLTGRDTG
MUL_3507|M.ulcerans_Agy99 ALEGAGGNGGHGGLLFGNGGGGGDAGANNKFVTAQATPNGAAGGYGGNAG
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG
TH_3810|M.thermoresistible__bu ---SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGG
MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLA----GNAGLAGNAG
MAV_4827|M.avium_104 AVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAPPPVQASAPQPK
Rv3595c|M.tuberculosis_H37Rv --EPGGPGQPGTEFGQTG---GTGGTGGTGLSVG--------GTGG---T
Mb3626c|M.bovis_AF2122/97 --EPGGPASQAPSSGKPV---APVALAVLACPLA--------GPAGPAET
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --GPGGPGADGTEYGQTG---GTGGTGGYGRVEG--------GDGGVGGV
MUL_3507|M.ulcerans_Agy99 LWGNGGAGGDG-GFGGTATVIGDGGTGGNGGLLS--------GDGGAGGV
Mflv_5091|M.gilvum_PYR-GCK KGGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGT
Mvan_1264|M.vanbaalenii_PYR-1 KGGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGT
MSMEG_0868|M.smegmatis_MC2_155 RGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGN
TH_3810|M.thermoresistible__bu HGGRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGN
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAG----NAGLAGNAGLAGNAG--------LAGNAGLA
MAV_4827|M.avium_104 ISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVV
Rv3595c|M.tuberculosis_H37Rv GGTGG---------TGGAGGSGGRGG------------------------
Mb3626c|M.bovis_AF2122/97 VAPAR---------PAAPGGPAGPAA------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M GGQG------------APGGVGGSGG------------------------
MUL_3507|M.ulcerans_Agy99 GGTGGIQ-------IYSGGGIGGVGG------------------------
Mflv_5091|M.gilvum_PYR-GCK GGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG--------
Mvan_1264|M.vanbaalenii_PYR-1 GGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG--------
MSMEG_0868|M.smegmatis_MC2_155 GGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATV
TH_3810|M.thermoresistible__bu GGDG---------------GNGGSAG------------------------
MAB_4284c|M.abscessus_ATCC_199 GNAG-------------LAGNAGLAG------------------------
MAV_4827|M.avium_104 VPPVPVPVPVRIPVPDPVSPPQLLAPPR----------------------
Rv3595c|M.tuberculosis_H37Rv ---------LLVGDG-----------------------------------
Mb3626c|M.bovis_AF2122/97 ---------LAVGVGSWSATAAQVASG-----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ---------AGGGGGHGG--LLVGNGG-----------------------
MUL_3507|M.ulcerans_Agy99 ---------IGGNGGAGGTSGLIGDGG-----------------------
Mflv_5091|M.gilvum_PYR-GCK ---------TGGTGGQGG-LGGGGGTG-----------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------TGGTGGQGG-LGGVGGTG-----------------------
MSMEG_0868|M.smegmatis_MC2_155 IGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATD
TH_3810|M.thermoresistible__bu ---------RGGTGGLRGVFGINGGNG-----------------------
MAB_4284c|M.abscessus_ATCC_199 ---------NAAVAGNAAVAGNAAVAG-----------------------
MAV_4827|M.avium_104 ---------LSVPQPVQPPVRVPQPPS-------------------PPQV
Rv3595c|M.tuberculosis_H37Rv --GAGGIGGT----GGEGGIGARG------------GTGGQGGMGGAGQP
Mb3626c|M.bovis_AF2122/97 AQGAKAASAP----GAAPAVRAEW------------AAPGNQALGVTLVT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M GGGAGGIGGG----GGTGAVGGTG------------GAGGAGGDSEFAGG
MUL_3507|M.ulcerans_Agy99 AGGAGGTGGGNAGVGGVGGVGGTGGAARLFGSGGSGGIGGTGGHSLINSG
Mflv_5091|M.gilvum_PYR-GCK GQGGTGGTGGQGGTGGTGGTGGTG------------GTGGAGGDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGTGGQGGTGGTGGTGGTG------------GTGGAGGDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155 GHGGSGINGGHGGNGGQGTIEANGPSAVASGI----GAGGNGGDGIDGGL
TH_3810|M.thermoresistible__bu -RAGLGGRGXXXXGGGVGAAVRSG-------------------NGVFSGG
MAB_4284c|M.abscessus_ATCC_199 -NAAVGGVLNTGVSGAIGGSSHVG-------------GAINESLGGSGSV
MAV_4827|M.avium_104 GGTVPQSPPQHQTPPGEGTPPKPD-------------GPGNYGGGHVPTP
Rv3595c|M.tuberculosis_H37Rv GVGGD----------AGDGGNGGIGGDGGA-------------------G
Mb3626c|M.bovis_AF2122/97 GVTAG----------SAVTAAPAETAARAA-------------------R
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M NGNTG-----------GDGGTGGTGGAGGD-------------------G
MUL_3507|M.ulcerans_Agy99 GGIGGKGGGGGAAGLIGDGGAGGAGGNGGDGTGAGGLGGNGASADWIGNG
Mflv_5091|M.gilvum_PYR-GCK GGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GS
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GS
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQS
TH_3810|M.thermoresistible__bu GGTPSAGFGVPTTIQFPAGSCTSRAVSREG--------------------
MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHTGVGGGVSTGVGVGSHVGG--------------------
MAV_4827|M.avium_104 GAGGSGGSGGGHVPTPGAGGSGGSGGGHVP------------------TP
Rv3595c|M.tuberculosis_H37Rv GDGGAGGAGGAGGLFGVSGSSG-LGGAAGS---------GGNGGGGGEPG
Mb3626c|M.bovis_AF2122/97 AARAACSASPVAPGWAVPPVAGVMAGAVVSPVWPAPRALGLRAVAATATS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M GNGGAGGAGGLLGHS----------GNPGLGGEGGT--------GGGGGD
MUL_3507|M.ulcerans_Agy99 GSGGAGGSGGLGAHAGAGGNGGSLYGNDGSGGAGGTGASGAGGNGGGGGA
Mflv_5091|M.gilvum_PYR-GCK GSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASG
MSMEG_0868|M.smegmatis_MC2_155 GYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTA
TH_3810|M.thermoresistible__bu ----IMPSSRAASARAG---------------------------AACASS
MAB_4284c|M.abscessus_ATCC_199 GISESLGGSGSVGGSTAVGGGAHTGVGGGVS----------TGVGVGSHV
MAV_4827|M.avium_104 GTGGPGGTGGSGGGHVPTPGAGTPGGSGGGHLPFPGAGSTPGGSGGGHLP
Rv3595c|M.tuberculosis_H37Rv VAGSPGVG---PAGRGGDGNLGQFGP-------EGAPGQPGQPGQPG---
Mb3626c|M.bovis_AF2122/97 ASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M GGHWGDGGGPGSGSRRGMSG-----------------SHGSYGQP---GG
MUL_3507|M.ulcerans_Agy99 AGMMGDGGAGGDGGDGSAAGGLGGDGGNADWLGNGGGGTGGFGLPPATGG
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
Mvan_1264|M.vanbaalenii_PYR-1 AQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGK
TH_3810|M.thermoresistible__bu TSRSRRSFCCSRA-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGGISESLGGSGSVGGSTAVG---------GGAHTGVGGGVNTGVGVGSH
MAV_4827|M.avium_104 TPGAGTPGGGLGGFGGGHAPAP----------GGGLGGGGGHAPAPGGGL
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 FCGQGVDLIAELG-------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M SGADG--AHGQPG-------------------------------------
MUL_3507|M.ulcerans_Agy99 FGGRGGRLFGSPGAQGRRALMCLSAACRC---------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-
Mvan_1264|M.vanbaalenii_PYR-1 GAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-
MSMEG_0868|M.smegmatis_MC2_155 GADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGISESLGGSGSVG-------GSTAVGGGAHTSAINDALGGSGSVGG-
MAV_4827|M.avium_104 GGFGGGHSGGGLGGLGGGHK------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSG
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSG
MSMEG_0868|M.smegmatis_MC2_155 TSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---------STAVGGGAHTSAINESMNSSINASHSSSMNESFGSSMGSHG
MAV_4827|M.avium_104 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv ---------------------------------
Mb3626c|M.bovis_AF2122/97 ---------------------------------
MLBr_01183|M.leprae_Br4923 ---------------------------------
MMAR_5099|M.marinum_M ---------------------------------
MUL_3507|M.ulcerans_Agy99 ---------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 TGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 AGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ---------------------------------
MAB_4284c|M.abscessus_ATCC_199 AAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 ---------------------------------