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MSFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAA TFHAQFVQTLSAGAGAYANAEAANVQQSLLNAINAPTQALLGRPLIGDGADGTAPGQNGGAGGLLYGNGG NGAAGVNAGIAGGSGGAAGLIGNGGSGGAGGAGAAGGSGGQGGLLYGNGGAGGNGGAATIPGGNGGAGGA GGNAWLFGNGGAGGLGAAGAAGAAGVNPLTVPAGQGSMGNNGEPGGPASQAPSSGKPVAPVALAVLACPL AGPAGPAETVAPARPAAPGGPAGPAALAVGVGSWSATAAQVASGAQGAKAASAPGAAPAVRAEWAAPGNQ ALGVTLVTGVTAGSAVTAAPAETAARAARAARAACSASPVAPGWAVPPVAGVMAGAVVSPVWPAPRALGL RAVAATATSASSALKVHPASPASRASPVDIVAAGPSAPRRLLEQLPSVTGPVEALARVEFCGQGVDLIAE LG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3626c | PE_PGRS59 | - | 100% (492) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1275c | PE_PGRS23 | 7e-95 | 53.74% (374) | PE-PGRS family protein |
| M. bovis AF2122 / 97 | Mb1121 | PE_PGRS22 | 7e-95 | 56.48% (347) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-36 | 38.49% (278) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3595c | PE_PGRS59 | 1e-149 | 77.25% (356) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 1e-13 | 41.30% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-21 | 35.66% (258) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_4270 | - | 2e-97 | 53.03% (379) | PE-PGRS family protein |
| M. avium 104 | MAV_1346 | - | 4e-22 | 34.18% (275) | PE family protein |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-38 | 32.38% (386) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_4332 | - | 8e-19 | 27.75% (382) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_1145 | - | 2e-86 | 50.38% (399) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_0928 | - | 4e-39 | 40.79% (277) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 -----------------------------MSGTQSAESDDDADDSEGDAS
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb3626c|M.bovis_AF2122/97 -----------------------------------------MS-FVIAVP
Rv3595c|M.tuberculosis_H37Rv -----------------------------------------MS-FVIAVP
MUL_1145|M.ulcerans_Agy99 -----------------------------------------MS-YVVASP
MLBr_01183|M.leprae_Br4923 -----------------------------------------MPLFLNAEP
MAV_1346|M.avium_104 -----------------------------------------MS-FVTTRP
MMAR_4270|M.marinum_M -----------------------------------------MS-FVFAVP
MAB_4284c|M.abscessus_ATCC_199 ---------------------------------------MSIIDFILNLF
TH_4332|M.thermoresistible__bu ------------------------------------------MPFITSGA
Mvan_0928|M.vanbaalenii_PYR-1 ADDAEDAEEFVGDSGNGGSDDDAADDSEKDVDSSTDDGVGDFEGVVLDDA
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb3626c|M.bovis_AF2122/97 ----------------------------------------EFLSAAATDL
Rv3595c|M.tuberculosis_H37Rv ----------------------------------------EFLSAAATDL
MUL_1145|M.ulcerans_Agy99 ----------------------------------------EYVAAAASDL
MLBr_01183|M.leprae_Br4923 ----------------------------------------QALTAAANTL
MAV_1346|M.avium_104 ----------------------------------------EALLAVASML
MMAR_4270|M.marinum_M ----------------------------------------ETMAAVTSEL
MAB_4284c|M.abscessus_ATCC_199 R---------------------------------------DPVEAASYVA
TH_4332|M.thermoresistible__bu ----------------------------------------AFVGGAAMLL
Mvan_0928|M.vanbaalenii_PYR-1 ----------------------------------------ESEADSQLSV
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb3626c|M.bovis_AF2122/97 AN---------------------------------------LGSTISAAN
Rv3595c|M.tuberculosis_H37Rv AN---------------------------------------LGSTISAAN
MUL_1145|M.ulcerans_Agy99 AG---------------------------------------IGSALSTAN
MLBr_01183|M.leprae_Br4923 EG---------------------------------------LSAATVASN
MAV_1346|M.avium_104 EG---------------------------------------LGSSMDAQN
MMAR_4270|M.marinum_M AT---------------------------------------IGSNLEMAN
MAB_4284c|M.abscessus_ATCC_199 DP---------------------------------------EAALANAGL
TH_4332|M.thermoresistible__bu AG--------------------------------------PGGVSALEAA
Mvan_0928|M.vanbaalenii_PYR-1 PQP--------------------------------------ASTESTEQS
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGN-GLG
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGV-GWA
Mb3626c|M.bovis_AF2122/97 AAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAATFHAQ-FVQ
Rv3595c|M.tuberculosis_H37Rv AAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQTISAQAATFHAQ-FVQ
MUL_1145|M.ulcerans_Agy99 AAAAAPTIEVLAAGADEVSAAIAAFFGAHAQAYQALSEQASAFHLQ-FVQ
MLBr_01183|M.leprae_Br4923 AAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQAHASQGATNHQD-LIQ
MAV_1346|M.avium_104 AAAAAPTTSIAPAAADEVSALQAAQFSAYGTWYQQVSAQAKAIHQT-LVQ
MMAR_4270|M.marinum_M AAAALPTTGLLAAGADEVSAAIAALFDEHALGYQTISAQASAFHAR-FMS
MAB_4284c|M.abscessus_ATCC_199 SAVSAAQVGAVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNY-YAA
TH_4332|M.thermoresistible__bu GSAPRTVEYEYSLVACDSTLPLMCEAGDSVGGLGGASHDRSAFSAS-ALG
Mvan_0928|M.vanbaalenii_PYR-1 ADVANDADGNADPIADAGPEAVTAPVALSGASAPAIPDGPAPVEPMGPLI
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGAT
MSMEG_0868|M.smegmatis_MC2_155 GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGT
Mb3626c|M.bovis_AF2122/97 TLSAGAGAYANAEAANVQ--QSL----LNAINAPTQALLGRPLIGDGADG
Rv3595c|M.tuberculosis_H37Rv TLSAGAGAYANAEAANVQ--QSL----LNAINAPTQALLGRPLIGDGADG
MUL_1145|M.ulcerans_Agy99 AMTAGAGAYAGAEAVNASPLQAA----LDVLNAPAQALFGRPLIGDGAGG
MLBr_01183|M.leprae_Br4923 SLLTSSSAYAGTETAN----------------------------------
MAV_1346|M.avium_104 NLDTNADSYGATEAANRV----------NTSAAALQGLAPNVIPNAAPAA
MMAR_4270|M.marinum_M ALNTGAGAYAAAEAANSSPLQALQDLTLNAINAPAQSLFGRPLIGDGANA
MAB_4284c|M.abscessus_ATCC_199 QPDGPSILSPSLLSPRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSF
TH_4332|M.thermoresistible__bu MASFGPDWNPGGAFLGLIG---------PGGLLIGDGLNGTDAYIDENGV
Mvan_0928|M.vanbaalenii_PYR-1 NSLWWAVPKSGGRSTNDASLTLAGTGIYPSVTSLFAFGGRCGLICDGADG
Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV
Mb3626c|M.bovis_AF2122/97 TAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAG-------------
Rv3595c|M.tuberculosis_H37Rv TAPGQNGGAGGLLYGNGGNGAAGVNAGIAGGSGGAAG-------------
MUL_1145|M.ulcerans_Agy99 -APGQSGGDGGLLYGNGGNGGNGG-VGQAGGAGGAAG-------------
MLBr_01183|M.leprae_Br4923 ------HDSL----------------------------------------
MAV_1346|M.avium_104 DPPPAGTTSLGTSIGWAQNVGAAASDFITLGEGQFAP-------------
MMAR_4270|M.marinum_M TTPGGNGGAGGILWGNGG-AGATGAAGQTGGNGGAAG-------------
MAB_4284c|M.abscessus_ATCC_199 NRGPLLDLSFGDLQFGNRDTTAIGDGAVAVGGSNSGP-------------
TH_4332|M.thermoresistible__bu FHEATRGGNGGLLWGNGGKGGNGLDAGLYTVPDPDNP-------------
Mvan_0928|M.vanbaalenii_PYR-1 TEQNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAG-------------
Mflv_5091|M.gilvum_PYR-GCK AVG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AVGAAG---AA
MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG
Mb3626c|M.bovis_AF2122/97 ---------LIGNGGSG----GAGG-------------------------
Rv3595c|M.tuberculosis_H37Rv ---------LIGNGGSG----GAGG-------------------------
MUL_1145|M.ulcerans_Agy99 ---------LIGNGGSG----GIGGPGTTGLAGGAGGSGGWLFGNGGTGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ---------VPGAAGIPNFNP-----------------------------
MMAR_4270|M.marinum_M ---------FIGNGGAG----GAGG-------------------------
MAB_4284c|M.abscessus_ATCC_199 --------IASGQGSTAVNGDVRDS-------------------------
TH_4332|M.thermoresistible__bu -------GSTIQMY------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 --------LLWGSGGDGGAGG-----------------------------
Mflv_5091|M.gilvum_PYR-GCK GTVGTAGATGGTG----TGANGGAGGVG-----GVGGTGAAGAAGGAG--
MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
Mb3626c|M.bovis_AF2122/97 ----------------------------------------AGAAGGSG--
Rv3595c|M.tuberculosis_H37Rv ----------------------------------------AGAAGGSG--
MUL_1145|M.ulcerans_Agy99 RGGIGTTGIGGIGGTGGDAVGLFGHGGTGGTGGNGPDIFIAGGAGGSG--
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------------------------------------GLTAATTA--
MMAR_4270|M.marinum_M ----------------------------------------AGATGGVG--
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------NIINADHG--
TH_4332|M.thermoresistible__bu ---------------------------------------FEASDGADG--
Mvan_0928|M.vanbaalenii_PYR-1 ----------------------------------------AGAAGGTG--
Mflv_5091|M.gilvum_PYR-GCK ----GLGETGTTG--------------GAGGVGGQGTAGGTGGVGGIG--
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
Mb3626c|M.bovis_AF2122/97 --------------------------------GQGGLLYGNGGAGG----
Rv3595c|M.tuberculosis_H37Rv --------------------------------GQGGLLYGNGGAGG----
MUL_1145|M.ulcerans_Agy99 --------------------------------GTGGLLFGNGGAGGGAPW
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------GPPAPAAPAAAAGA----
MMAR_4270|M.marinum_M --------------------------------GSGGMLFGNGGAGG----
MAB_4284c|M.abscessus_ATCC_199 --------------------------------SNVGVDQSQTRVGG----
TH_4332|M.thermoresistible__bu --------------------------------GRGGFLFGNGGDGG----
Mvan_0928|M.vanbaalenii_PYR-1 --------------------------------GNAGLLWGNGGHGG----
Mflv_5091|M.gilvum_PYR-GCK ---------------------GAGSTGAVGG-----------VGGKGIQG
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
Mb3626c|M.bovis_AF2122/97 ------------------NGGAATIPG-----------------------
Rv3595c|M.tuberculosis_H37Rv ------------------NGGAATIPG-----------------------
MUL_1145|M.ulcerans_Agy99 ------------GGADGGAGGDARLIGNGGGGGYEGSLGVLSGGTAGPGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M ------------------NGGTAMVVG-----------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 -------------------AGGAGVNGAVGTSG-----------------
Mflv_5091|M.gilvum_PYR-GCK GQGLQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
Mb3626c|M.bovis_AF2122/97 ---------GNGGAGGAGGN-------------------------AWLFG
Rv3595c|M.tuberculosis_H37Rv ---------GNGGAGGAGGN-------------------------AWLFG
MUL_1145|M.ulcerans_Agy99 DGGNAVGLIGNGGAGGAGAAGLSGVTGG---------IGGNGGNGAQLFG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -------------PVLASMGRGPSIG------------------------
MMAR_4270|M.marinum_M ---------GTGGNGGAGGS-------------------------AGLFG
MAB_4284c|M.abscessus_ATCC_199 ------DYTNVSGHGSADIDKSVTVVDDHS--------QRNTTNINDSFN
TH_4332|M.thermoresistible__bu ---------NGGNVGGKNGADPVTAT------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ------VNNGRGGDGTAGGSGGAGGN------------------AGLLSG
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNG------------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
Mb3626c|M.bovis_AF2122/97 NGGAGGLG---------------------AAGAAGAAGVN---PLTVP--
Rv3595c|M.tuberculosis_H37Rv NGGAGGLG---------------------AAGAAGAAGVN---PLTVP--
MUL_1145|M.ulcerans_Agy99 NGGAGGAGGQSQLASGGTGGSGGMAALFGNGGAGGAAGVS---LSGAPGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 -----------------------------------GLSVP---PSWAP--
MMAR_4270|M.marinum_M AGGAGGQGGQGAQGPDAVNPGPVSPTGQATSGTGGGVGENGGPGDSSTVT
MAB_4284c|M.abscessus_ATCC_199 TDRSTNIGSGNTTNTEIGSHNQANIGTSTSAGGSAAVGGNAGLAGNAG--
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 RGGDGGVGGAGGKGGAG-----AHGSDAVAAEEDGGPGGSGGAGGNAGAG
Mflv_5091|M.gilvum_PYR-GCK ----------ADGGTGGAGGAGGTGG-TGGAGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQH---
Mb3626c|M.bovis_AF2122/97 ---------AGQGSMGNNGEPGGPASQA----------------------
Rv3595c|M.tuberculosis_H37Rv ---------AGQGSMGNNGEPGGPGQPG----------------------
MUL_1145|M.ulcerans_Agy99 GGNGGSAQFMGDGDSGGLGDSGGSAGAAGAGGLIGNPLDVVNAPTEALLG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 ----------GGVAPAANATPAQLVGAG----------------------
MMAR_4270|M.marinum_M GEEGGDGGSGGQGSPGASTASGGTGGDGGLAG------------------
MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAGLAGNAGLAGNAG------------------
TH_4332|M.thermoresistible__bu ----------VAADKSVAGGNGGNGGRGG---------------------
Mvan_0928|M.vanbaalenii_PYR-1 GVGGRGALLFGRGGDGGDGGSAGTGGAGGFGG------------------
Mflv_5091|M.gilvum_PYR-GCK -----------TGGTGGIGGAGSTGGTGGTGGTGGTGGTG--GTG-GTGG
MSMEG_0868|M.smegmatis_MC2_155 -----STGQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAG--GVSEGEGG
Mb3626c|M.bovis_AF2122/97 ------------PSSGKP---------------VAPVALA--VLACPLAG
Rv3595c|M.tuberculosis_H37Rv ------------TEFGQT---------------GGTGGTG--GTGLSVGG
MUL_1145|M.ulcerans_Agy99 RPLIGDGADGAPGESGQDGGLLYGNGGNGGNGLSGQAGGA--GGAAGLIG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------FTSAAPDT--APVTAVPG
MMAR_4270|M.marinum_M ------DGGPGAPGGTGGGGGNGGAGANNFSGGSATSGGA--GGNGNNGG
MAB_4284c|M.abscessus_ATCC_199 -----------LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAG
TH_4332|M.thermoresistible__bu -------------------------------LLFGLGGNGGNGGWSTTSY
Mvan_0928|M.vanbaalenii_PYR-1 ----------------TGGAIVVTLPGGKLSDSDGAGGAGGVGGAAGLGG
Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGGTG--------
MSMEG_0868|M.smegmatis_MC2_155 TGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSH
Mb3626c|M.bovis_AF2122/97 PAGPAETVAPARPAAPGGPAGPAALAVGVGSW------------------
Rv3595c|M.tuberculosis_H37Rv TGG---TGGTGGTGGAGGSGGRGGLLVGDG--------------------
MUL_1145|M.ulcerans_Agy99 NGGNGGIGGPGTTGMSGGAGGAGGWLIGNGGHGGIGGLGIGIG-------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 GVPSMATAGRGGYGLGAPRYGVKPTVMPKPAI------------------
MMAR_4270|M.marinum_M TGGDGAAGGDGGNGGNGGSGGTTTSKVSNAGSGANGGDGGDGG-------
MAB_4284c|M.abscessus_ATCC_199 NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGN-------
TH_4332|M.thermoresistible__bu LDARGGNGGNGGLGGVLRPGGLLSLLLPSGAASEPGG-------------
Mvan_0928|M.vanbaalenii_PYR-1 DGGGGGLGGLLGQAGVNGDSGATAAAGNAGGVGGAGGLGGRLPIVDLN--
Mflv_5091|M.gilvum_PYR-GCK -GTGGTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQG
MSMEG_0868|M.smegmatis_MC2_155 TGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDG
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ----------------------------------------NASPAQATLA
Mflv_5091|M.gilvum_PYR-GCK G-----------------TGGTGGQGG-LGGGGGTG--------------
MSMEG_0868|M.smegmatis_MC2_155 GEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQAN
Mb3626c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1145|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 ALIKKLGLPIQAATGIQLEDVDGRLVGPLNAYLYNTIIGKAIFDVGNTFS
Mflv_5091|M.gilvum_PYR-GCK ---------GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDG
MSMEG_0868|M.smegmatis_MC2_155 PQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDG
Mb3626c|M.bovis_AF2122/97 ------------SATAAQVASGAQGAKAASAPG-------AAPAVRAEWA
Rv3595c|M.tuberculosis_H37Rv ------------------------GAGGIGGTG-------GEGGIGARGG
MUL_1145|M.ulcerans_Agy99 --------DSGGAGGAGGAAIGLFGNGGTGGTGGYNQAFGAVSGVGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M --------D--GGAGAVGGNGGNGGKGGDSGSGGFFTPSPGTGGAGGDGG
MAB_4284c|M.abscessus_ATCC_199 ----------AGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVGGVLNTG
TH_4332|M.thermoresistible__bu -----------------LFTGGNGGNGGLAIANHWVGITDGVPGPDDDAV
Mvan_0928|M.vanbaalenii_PYR-1 SASLSARVKEIVILSVGGQWGSEYELYAHKLAAQLFGIPADAIAALANGQ
Mflv_5091|M.gilvum_PYR-GCK GLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG-
MSMEG_0868|M.smegmatis_MC2_155 IDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGP
Mb3626c|M.bovis_AF2122/97 AP----GNQALGVTLVTGVTAGSAVTA-----------------------
Rv3595c|M.tuberculosis_H37Rv TG----GQGGMGGAGQPGVGGDAGDGG-----------------------
MUL_1145|M.ulcerans_Agy99 AGGQWYGNGGDGGTSWGGAAAGAGGDAGLIDNGGDGDSAGVLRQNGIGGH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M HG----GSGSNGQAGGSGGQGGAGGNGGLLAGDGGAGGAGGLGGQGGAAA
MAB_4284c|M.abscessus_ATCC_199 VSGAIGGSSHVGGAINESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVGVG
TH_4332|M.thermoresistible__bu SSSAYGGHGGHGAGPGSGGNGGS---------------------------
Mvan_0928|M.vanbaalenii_PYR-1 APVGLSGNELLAAQFVQELVSTRRVSDALFEAAEAAFGQTGVVDMVNLAG
Mflv_5091|M.gilvum_PYR-GCK ---GSGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-A
MSMEG_0868|M.smegmatis_MC2_155 SWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVA
Mb3626c|M.bovis_AF2122/97 ----------------------------------------------APAE
Rv3595c|M.tuberculosis_H37Rv ----------------------------------------------NGGI
MUL_1145|M.ulcerans_Agy99 GGAGGSLFGDGGDGGSAGFQSTAGDGGNAGLVGNGGNGGWAIYNSFAGDD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M AGANGGVAGNGGNGGHGPFGEKIPAGGSGGDGGTGGIGG-------DGGL
MAB_4284c|M.abscessus_ATCC_199 SHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGGVSTGVG------VGSH
TH_4332|M.thermoresistible__bu -------------------------------------------------A
Mvan_0928|M.vanbaalenii_PYR-1 TYLGVSATLNAFKVRGPESFSAPVLPAAPSPVPASDEYGLGGRLPLIDLD
Mflv_5091|M.gilvum_PYR-GCK TGAAGKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NG
MSMEG_0868|M.smegmatis_MC2_155 TGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNG
Mb3626c|M.bovis_AF2122/97 TAARAARAARAACSASPVAPGWA--------------VPPVAGVMAGAVV
Rv3595c|M.tuberculosis_H37Rv GGDGGAGGDGGAGGAGGAGGLFG--------------VSGSSG-LGGAAG
MUL_1145|M.ulcerans_Agy99 GSGGTAIGNGGDGGANIVSSGFI--------------LGAGGGGNGGNAV
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M GGDGGAGGQGGAGGRAGLLAGLG--------------GAGGDGGLGGNGG
MAB_4284c|M.abscessus_ATCC_199 VGGGISESLGGSGSVGGSTAVGG-------------GAHTGVGGGVNTGV
TH_4332|M.thermoresistible__bu VANSLGNAIAGNGGDAGRFVLIG---------------------------
Mvan_0928|M.vanbaalenii_PYR-1 TATPAQLDLAAKIKALAVPTQQATG----------IELVSPDGRLIGPLN
Mflv_5091|M.gilvum_PYR-GCK ANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAG
MSMEG_0868|M.smegmatis_MC2_155 GNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDG
Mb3626c|M.bovis_AF2122/97 SPVWPAPRA------------------------LGLRAVAATATSASSAL
Rv3595c|M.tuberculosis_H37Rv S---------------------------------GGNGGGGGEPGVAGSP
MUL_1145|M.ulcerans_Agy99 GLIGNGGAGGTGADGFSTALGSDGGNGGTGAWLLGNGGAGGSGGSTAGVH
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M VGGDGAQGGLGGNGGVRNSDNLSYDGIIGNGGTGGNGGVGGHGGDGGAGG
MAB_4284c|M.abscessus_ATCC_199 GVGSHVGGGISESLGGSGSVGGSTAVGGGAHTSAINDALGGSGSVGGSTA
TH_4332|M.thermoresistible__bu --------------------------------------------------
Mvan_0928|M.vanbaalenii_PYR-1 GYLYNPVIGQALFEVGNAFASSSLSSRIKEIVILSVGGQWGSGYEVYAHE
Mflv_5091|M.gilvum_PYR-GCK GAGG-----------------AGGEGGEGGDGGKGGAG--AEGGAGGGGG
MSMEG_0868|M.smegmatis_MC2_155 GNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGG
Mb3626c|M.bovis_AF2122/97 KVHP------------------ASPASRASPVDIVAAGPSAPRRLLEQLP
Rv3595c|M.tuberculosis_H37Rv GVG---------------------PAGRGGDGNLGQFGP-------EGAP
MUL_1145|M.ulcerans_Agy99 PAGD------------------GGNSGMSALIGNGGAGGSAGVSPTGVFP
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_1346|M.avium_104 --------------------------------------------------
MMAR_4270|M.marinum_M EGGS------------------GSLLGAAGSAGSNAAGGSGGTGGLRGQG
MAB_4284c|M.abscessus_ATCC_199 VGGG-------------------AHTSAINESMNSSINASHSSSMNESFG
TH_4332|M.thermoresistible__bu ------------------------PGGNGGNGGTGLXXXPRPRRRRNHRR
Mvan_0928|M.vanbaalenii_PYR-1 KVARLVGIPEEAIVSLASGHAPVGLSGSELVAARFVQELVSTYEVSSELY
Mflv_5091|M.gilvum_PYR-GCK AGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD-------
MSMEG_0868|M.smegmatis_MC2_155 TGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-------
Mb3626c|M.bovis_AF2122/97 SVTGPVEALARVEFCGQG---------------VDLIAELG----
Rv3595c|M.tuberculosis_H37Rv GQPGQPGQPG-----------------------------------
MUL_1145|M.ulcerans_Agy99 SNGGSGGNAQLIGDGGDGGRGDSGGTGGAGGTGGSLAGHDGSDGD
MLBr_01183|M.leprae_Br4923 ---------------------------------------------
MAV_1346|M.avium_104 ---------------------------------------------
MMAR_4270|M.marinum_M GDPGSTGRAGTGSAGADGMNGTDGDPGDPGGMA------------
MAB_4284c|M.abscessus_ATCC_199 SSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH--------
TH_4332|M.thermoresistible__bu TRRRPNGRRPRPPPGR-----------------------------
Mvan_0928|M.vanbaalenii_PYR-1 HSAEAAFGQAGLVDLVNLASTYLGASALLNVFEVPVPTAALITTS