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PLVFATPEIIAAAATDLAQIGSAISGANTAAAAPTTEVLAAGADEVSTVVASLFSRYAQAYQVLGADMAA IHDQFVQALNAGANWYAGVESANSSTLQTVQQDVLGLINAPTQALLGRGLIGDGAAGTASHPDGYDGGFL YGSGGSGYNSATSGVGGGAGGAAGLIGNGGAGGAGGAAAAGGSGGQGGWLYGNGGVGGAGGAASTAGGSG GLGGAGGNAGLWGNGGAGGAGGDGTAGAAGVNPTTMPAGNGTPGLTGRDTGGPGGPGADGTEYGQTGGTG GTGGYGRVEGGDGGVGGVGGQGAPGGVGGSGGAGGGGGHGGLLVGNGGGGGAGGIGGGGGTGAVGGTGGA GGAGGDSEFAGGNGNTGGDGGTGGTGGAGGDGGNGGAGGAGGLLGHSGNPGLGGEGGTGGGGGDGGHWGD GGGPGSGSRRGMSGSHGSYGQPGGSGADGAHGQPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_5099 | - | - | 100% (456) | PE-PGRS family protein |
| M. marinum M | MMAR_1162 | - | e-146 | 54.62% (509) | PE-PGRS family protein |
| M. marinum M | MMAR_1161 | - | e-139 | 52.62% (515) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3402 | PE_PGRS51 | 1e-143 | 51.25% (560) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 3e-83 | 52.20% (341) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3595c | PE_PGRS59 | 1e-157 | 62.23% (458) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 3e-12 | 37.37% (99) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 6e-41 | 37.64% (356) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 1e-24 | 43.09% (181) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 2e-68 | 45.14% (370) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-44 | 40.94% (298) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3507 | - | 1e-128 | 51.80% (529) | PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 8e-81 | 49.70% (336) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------MSIIDF
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_3507|M.ulcerans_Agy99 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVAS--
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu ------------------------------------------------VD
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Mb3402|M.bovis_AF2122/97 ------------------------------------MS-FVVAVPEALAA
MLBr_01183|M.leprae_Br4923 ------------------------------------MPLFLNAEPQALTA
MMAR_5099|M.marinum_M ------------------------------------MP-LVFATPEIIAA
Rv3595c|M.tuberculosis_H37Rv ------------------------------------MS-FVIAVPEFLSA
MUL_3507|M.ulcerans_Agy99 ------------------------------------MS-FVSVTQEALAA
MAB_4284c|M.abscessus_ATCC_199 --------NYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLS
MAV_4827|M.avium_104 -------MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAA
TH_3810|M.thermoresistible__bu GDGGSGGRTGLFSKLSRGGDGGDGGLGGNGGHGGGTGIISLLSLAGNGGN
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
Mb3402|M.bovis_AF2122/97 AASDVANIGSALSAANAAAAAGTTGLLAAGADEVSAALASLFSGHAVSYQ
MLBr_01183|M.leprae_Br4923 AANTLEGLSAATVASNAAAAQLTTEIAPPAADDVSILLAHFFSGHGRQYQ
MMAR_5099|M.marinum_M AATDLAQIGSAISGANTAAAAPTTEVLAAGADEVSTVVASLFSRYAQAYQ
Rv3595c|M.tuberculosis_H37Rv AATDLANLGSTISAANAAASIPTTGVLAAGADDVSAAIAALFGAHAQAYQ
MUL_3507|M.ulcerans_Agy99 AASDVGVIGSSLQAANMSVAAPTAGVLAAGADEVSVAMAALFSGHGQAYQ
MAB_4284c|M.abscessus_ATCC_199 PRDNDFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQ
MAV_4827|M.avium_104 TASAPDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARR
: .
TH_3810|M.thermoresistible__bu GGNGYRTTDNNALDGGHGGNGGNVGFFSLFN-------------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
Mb3402|M.bovis_AF2122/97 QVAAQATALHDQFVQALTGAGGSYALTEAANV------------------
MLBr_01183|M.leprae_Br4923 AHASQGATNHQDLIQSLLTSSSAYAGTETAN-------------------
MMAR_5099|M.marinum_M VLGADMAAIHDQFVQALNAGANWYAGVESANSSTL---------------
Rv3595c|M.tuberculosis_H37Rv TISAQAATFHAQFVQTLSAGAGAYANAEAAN-------------------
MUL_3507|M.ulcerans_Agy99 TLSAQANAFHAQFLQALTNAGGAYAAAEVANLSPL---------------
MAB_4284c|M.abscessus_ATCC_199 FGNRDTTAIGDGAVAVGGSNSGPIASGQGSTAVNG---------------
MAV_4827|M.avium_104 IDNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEP--------------
. .
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----------------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
Mb3402|M.bovis_AF2122/97 --------QQNLLNAINAPTQALLGRPLIGDGAVG--------------T
MLBr_01183|M.leprae_Br4923 --------HDSL--------------------------------------
MMAR_5099|M.marinum_M -----QTVQQDVLGLINAPTQALLGRGLIGDGAAG--------------T
Rv3595c|M.tuberculosis_H37Rv -------VQQSLLNAINAPTQALLGRPLIGDGADG--------------T
MUL_3507|M.ulcerans_Agy99 -----QGVEQGVLGVVNAPAQALLGRPLIGDGAAG--------------T
MAB_4284c|M.abscessus_ATCC_199 --------DVRDSNIINADHGSNVGVDQSQTRVGG------------DYT
MAV_4827|M.avium_104 -DTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLS------------A
TH_3810|M.thermoresistible__bu -LGGAGG---------------------------------------WGGS
Mflv_5091|M.gilvum_PYR-GCK AVGAAGAAG------TVGTAGATGGTG---------------TGANGGAG
Mvan_1264|M.vanbaalenii_PYR-1 AIGTAGVAG------AAGTAGATGGTG---------------VGGNGGAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
Mb3402|M.bovis_AF2122/97 ASSPDGQDGG-----LLFGNGGAGYNSA------------ATPGMAGGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ASHPDGYDGG-----FLYGSGGSGYNS-------------ATSGVGGGAG
Rv3595c|M.tuberculosis_H37Rv APGQNGGAGG-----LLYGNGGNGAAG-------------VNAGIAGGSG
MUL_3507|M.ulcerans_Agy99 AASPNGGAGG-----LLYGNGGAGYSYTS-----------GATAEAGGNG
MAB_4284c|M.abscessus_ATCC_199 NVSGHGSADIDKSVTVVDDHSQRNTTNIN-----DSFNTDRSTNIGSGNT
MAV_4827|M.avium_104 MVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALA
TH_3810|M.thermoresistible__bu GVDGVDVVGGNP---------------DGGTPGAHGESHTPG--VYTDRQ
Mflv_5091|M.gilvum_PYR-GCK GVGGVGGTGAAG--------------AAGGAGGLGETGTTGG--AGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 QAGGIGGTGAAG--------------AAGQAGTAGETGVTGG--VGGIGG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGG--AGGMGE
Mb3402|M.bovis_AF2122/97 GNAGLIGNGGTG--------------GSGGAGAAGGAGGSGG--WLYGNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M GAAGLIGNGGAG--------------GAGGAAAAGGSGGQGG--WLYGNG
Rv3595c|M.tuberculosis_H37Rv GAAGLIGNGGSG--------------GAGGAGAAGGSGGQGG--LLYGNG
MUL_3507|M.ulcerans_Agy99 GAAGLIGNGGAG--------------GSGWAGGAGGAGGNGG--WLYGNG
MAB_4284c|M.abscessus_ATCC_199 TNTEIGSHNQAN---------------IGTSTSAGGSAAVGGNAGLAGNA
MAV_4827|M.avium_104 RGAALAAANAPLFASS----TAALAYAQDPGTGAVDQYSLPDYLYVPVDP
TH_3810|M.thermoresistible__bu GEDGEDGTGTGIGGRGGNGGSSSGTHPMAED-------------------
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
Mb3402|M.bovis_AF2122/97 GNGGIGGNAIVAGGAGGNGGAGGAAGLWGSG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M GVGGAGGAASTAGGSGGLGGAGGNAGLWGNG-------------------
Rv3595c|M.tuberculosis_H37Rv GAGGNGGAATIPGGNGGAGGAGGNAWLFGNG-------------------
MUL_3507|M.ulcerans_Agy99 GAGGLGGAAAGDYTAGGVGGAGGNAGLWGDG-------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG-------------------
MAV_4827|M.avium_104 EPGDDELAYSAVGEEDAESPTVVIEKLFLPE-------------------
TH_3810|M.thermoresistible__bu ----GEHVKALDGRPGLDGGN-----------------------------
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
Mb3402|M.bovis_AF2122/97 ----GSGGQGGNGLTGNDGVNPAPVTNPALNGAAGDSNIEPQTSVLIGTQ
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ----GAGGAGGDGTAGAAGVNPTTMP------------------------
Rv3595c|M.tuberculosis_H37Rv ----GAGGLGAAGAAGAAGVNPLTVP------------------------
MUL_3507|M.ulcerans_Agy99 ----GAGGNGSATYDYDQNFSRLGALEG----------------------
MAB_4284c|M.abscessus_ATCC_199 ----LAGNAGLAGNAGLAGNAGLAGNAG----------------------
MAV_4827|M.avium_104 ----DSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
Mb3402|M.bovis_AF2122/97 GGDGTPGGAGVNGGNGGAGGDANGNPANTSIANAGAGGNGA---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ------------------------------------AGNGT---------
Rv3595c|M.tuberculosis_H37Rv ------------------------------------AGQGS---------
MUL_3507|M.ulcerans_Agy99 -AGGNGGHGGLLFGNGGGGGDAGANNKFVTAQATPNGAAGG---------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------LAGNAGLAGNAG-------
MAV_4827|M.avium_104 PNQHLIVPTEQAPAPPPVQASAPQPKISVPEPVAAPKPLSPP--------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG-------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG-------------
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
Mb3402|M.bovis_AF2122/97 ------------AGGDGGANGGAGGAGGQAASAGSSVG------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ------------PGLTGRDTGGPGGPG----ADGTEYG------------
Rv3595c|M.tuberculosis_H37Rv ------------MGNN----GEPGGPG----QPGTEFG------------
MUL_3507|M.ulcerans_Agy99 ------------YGGNAGLWGNGGAGGDGGFGGTATVI------------
MAB_4284c|M.abscessus_ATCC_199 ------------LAGNAGLAGNAGLAGNAGLAGNAGLAG-----------
MAV_4827|M.avium_104 ------------VAAPLPAAPPPAAPPLPEAPPIPAAPP-----------
TH_3810|M.thermoresistible__bu ----------------------------------GSHGGNGGHGGRGGFL
Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTG----GTGGTG-GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTG----GTGGTG-GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAG----GAGGVSEGEGGTGGHG
Mb3402|M.bovis_AF2122/97 ---GDGGNGGAGGTGTNGHAGGAGGAGGQAASAGSSVGGDGGNGGAGGTG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M ---QTGGTGGTGGYG-------------------RVEGGDGGVGGVGGQG
Rv3595c|M.tuberculosis_H37Rv ---QTGGTGGTGGTG-------------------LSVGGTGGTG------
MUL_3507|M.ulcerans_Agy99 ---GDGGTGGNGGLLSGD--GGAGGVGGTGGIQIYSGGGIGGVGGIGGNG
MAB_4284c|M.abscessus_ATCC_199 ---NAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGNAAVG
MAV_4827|M.avium_104 -VVPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVP
TH_3810|M.thermoresistible__bu GIGGSGGWGGHGGNGGDTDAD-GGNGGDGGNGGSAGRG---------GTG
Mflv_5091|M.gilvum_PYR-GCK GTGGKGGTGGTGGAGGTG-----GDGGTGGTGGTGGTG---------GTG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGKGGTGGTGGDGGTG-----GTGGTGGTGGTGGTG---------GTG
MSMEG_0868|M.smegmatis_MC2_155 GDGGRGGDGALGGNGGTGGVG-LGNGGKGGNGGNGGNGGTYVDPSHTGAG
Mb3402|M.bovis_AF2122/97 TNGHAGGAGGAGGAGGRGGWL-VGSGGNGGNGGNGAAG---------GNG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M APGGVGGSGGAGGGGGHGGLL-VGNGGGGGAGGIGGGG---------GTG
Rv3595c|M.tuberculosis_H37Rv ---GTGGTGGAGGSGGRGGLL-VGDGGAGGIGGTGGEG---------GIG
MUL_3507|M.ulcerans_Agy99 GAGGTSGLIGDGGAGGAGGTG-GGNAGVGGVGGVGGTG---------GAA
MAB_4284c|M.abscessus_ATCC_199 GVLNTGVSGAIGGSSHVGGAINESLGGSGSVGGSTAVG---------GGA
MAV_4827|M.avium_104 QPPSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYGG--------GHV
TH_3810|M.thermoresistible__bu GLRGVFGIN---------GGNGRAGLGGRGX-------------------
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---
MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEAL
Mb3402|M.bovis_AF2122/97 AIGGTGGAGGVPANQGGNSALGTQPVSGDGG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M AVGGTGGAG-------GAGGDSE-FAGGNGN-------------------
Rv3595c|M.tuberculosis_H37Rv ARGGTGGQG-------GMGGAGQPGVGGDAG-------------------
MUL_3507|M.ulcerans_Agy99 RLFGSGGSGGIGGTGGHSLINSGGGIGGKGG-------------------
MAB_4284c|M.abscessus_ATCC_199 HTGVGGGVSTGVGVGSHVGGGISESLGGSGS-------------------
MAV_4827|M.avium_104 PTPGAGGSG----------GSGGGHVPTPG--------------------
TH_3810|M.thermoresistible__bu ---------------XXXGGGVG---------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------TGGTGGQGG-LGGGGGTG------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------TGGTGGQGG-LGGVGGTG------------------
MSMEG_0868|M.smegmatis_MC2_155 IRATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQAS
Mb3402|M.bovis_AF2122/97 --------------DGGNGGTGG---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------TGGDGGTGG---------------------------
Rv3595c|M.tuberculosis_H37Rv --------------DGGNGGIGG---------------------------
MUL_3507|M.ulcerans_Agy99 --------------GGGAAGLIG---------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------VGGSTAVGG---------------------------
MAV_4827|M.avium_104 --------------AGGSGGSGG---------------------------
TH_3810|M.thermoresistible__bu --------------------------------------AAVRSGNGVFSG
Mflv_5091|M.gilvum_PYR-GCK -----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGG
Mvan_1264|M.vanbaalenii_PYR-1 -----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGG
MSMEG_0868|M.smegmatis_MC2_155 GTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGG
Mb3402|M.bovis_AF2122/97 --------------------------------------TGGRGGDGGSGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M --------------------------------------TGGAGGDGGNGG
Rv3595c|M.tuberculosis_H37Rv --------------------------------------DGGAGGDGGAGG
MUL_3507|M.ulcerans_Agy99 --------------------------------------DGGAGGAGGNGG
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------GAHTGVGGGVSTGVG
MAV_4827|M.avium_104 -------------------------------------GHVPTPGTGGPGG
TH_3810|M.thermoresistible__bu GGG-----------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK LGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----G
Mvan_1264|M.vanbaalenii_PYR-1 LGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----G
MSMEG_0868|M.smegmatis_MC2_155 LGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQ
Mb3402|M.bovis_AF2122/97 AGGASG--------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M AGGAGG--------------------------------------------
Rv3595c|M.tuberculosis_H37Rv AGGAGG--------------------------------------------
MUL_3507|M.ulcerans_Agy99 DGTGAG--------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGSHVG--------------------------------------------
MAV_4827|M.avium_104 TGGSGG--------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAA
Mvan_1264|M.vanbaalenii_PYR-1 SGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGAS
MSMEG_0868|M.smegmatis_MC2_155 SGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNT
Mb3402|M.bovis_AF2122/97 -----WLMGNGGNGGNGGTGGSGGVGGNGGIGGDGAGGGNATSTSSIPFD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M -----LLG------------------------------------------
Rv3595c|M.tuberculosis_H37Rv -----LFG------------------------------------------
MUL_3507|M.ulcerans_Agy99 -----GLGGNGASADWIGNGGSGGAGGSGGLGAHAGAGGNGGSLYGNDGS
MAB_4284c|M.abscessus_ATCC_199 ------GGISESLGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVGSHVGGG
MAV_4827|M.avium_104 --------------------------------------------------
TH_3810|M.thermoresistible__bu --TPSAGFGVPTTIQFPAG-------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGS
Mvan_1264|M.vanbaalenii_PYR-1 GAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGS
MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGG
Mb3402|M.bovis_AF2122/97 AHGGNGGAGGDAGHGGTGG-------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M -HSGNPGLGGEGGTGGGGG-------------------------------
Rv3595c|M.tuberculosis_H37Rv -VSGSSGLGGAAGSGGNGG-------------------------------
MUL_3507|M.ulcerans_Agy99 GGAGGTGASGAGGNGGGGG-------------------------------
MAB_4284c|M.abscessus_ATCC_199 ISESLGGSGSVGGSTAVGG-------------------------------
MAV_4827|M.avium_104 GHVPTPGAGTPGGSGGGHLP------------------------------
TH_3810|M.thermoresistible__bu --------------------------SCTSRAVSREGIMPSSRAASARAG
Mflv_5091|M.gilvum_PYR-GCK QGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG
Mvan_1264|M.vanbaalenii_PYR-1 QGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG
MSMEG_0868|M.smegmatis_MC2_155 KGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGG
Mb3402|M.bovis_AF2122/97 -------------------------DGGDGGHAGTGGRGGLLAGQHANSG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M -------------------------DGGHWGDGGGPGSG-SRRGMSGSHG
Rv3595c|M.tuberculosis_H37Rv -------------------------GGGEPGVAGSPGVGPAGRGGDGNLG
MUL_3507|M.ulcerans_Agy99 -------------------------AAGMMGDGGAGGDGGDGSAAGGLGG
MAB_4284c|M.abscessus_ATCC_199 -------------------------GAHTSAINDALGGSGSVGGSTAVGG
MAV_4827|M.avium_104 ------------------------FPGAGSTPGGSGGGHLPTPGAGTPGG
TH_3810|M.thermoresistible__bu -------------------AACASSTSRSR---------RSFCCSRA---
Mflv_5091|M.gilvum_PYR-GCK -----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGS
Mvan_1264|M.vanbaalenii_PYR-1 -----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGS
MSMEG_0868|M.smegmatis_MC2_155 NTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGT
Mb3402|M.bovis_AF2122/97 -----------NGG-----GGGTGGAGGTH---------GTPGSGNAGGT
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MMAR_5099|M.marinum_M -----------SYG-----QPGGSGADGAH---------GQPG-------
Rv3595c|M.tuberculosis_H37Rv -----------QFG-----PEGAPGQPGQP---------GQPG-------
MUL_3507|M.ulcerans_Agy99 -----------DGGNADWLGNGGGGTGGFG---------LPPATGGFGGR
MAB_4284c|M.abscessus_ATCC_199 --------GAHTSAINESMNSSINASHSSS--------MNESFGSSMGSH
MAV_4827|M.avium_104 -------------------GLGGFGGGHAP----------APGGGLGGGG
TH_3810|M.thermoresistible__bu ----------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 TAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
Mb3402|M.bovis_AF2122/97 GTGNADSTNGGPGSDGLGGDAFNGSRGTDGNPG-
MLBr_01183|M.leprae_Br4923 ----------------------------------
MMAR_5099|M.marinum_M ----------------------------------
Rv3595c|M.tuberculosis_H37Rv ----------------------------------
MUL_3507|M.ulcerans_Agy99 GGRLFGSPGAQGRRALMCLSAACRC---------
MAB_4284c|M.abscessus_ATCC_199 GAAGTGFEAQGHAQGHASETAHTTLPGAEHH---
MAV_4827|M.avium_104 GHAPAPGGGLGGFGGGHSGGGLGGLGGGHK----