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LSISAVVFDRDGVLTSFDWTRAEEDVRRITGLPLEEIERRWGGWLNGLTIDDAFVETQPISEFLSSLARE LELGSKARDELVRLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLVSARSLLQCAALHDLVDVVLS SQMIGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADWVEGARCAGMRAYLVDRSGQTRDGVVRDLSSLGA ILDGAGP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3376 | - | - | 100% (217) | hypothetical protein Rv3376 |
| M. tuberculosis H37Rv | Rv3400 | - | 6e-05 | 25.10% (243) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3410 | - | 1e-121 | 100.00% (217) | hypothetical protein Mb3410 |
| M. gilvum PYR-GCK | Mflv_0023 | - | 7e-07 | 31.93% (119) | HAD family hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4086 | - | 1e-08 | 39.29% (112) | transferase |
| M. smegmatis MC2 155 | MSMEG_1078 | - | 9e-07 | 27.73% (119) | hydrolase |
| M. thermoresistible (build 8) | TH_2509 | - | 1e-05 | 29.57% (186) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0949 | - | 7e-09 | 33.61% (119) | HAD family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 MRHDDYTLVIPTVGRESLRRLLIALRESMGPQPPEVVVVDDRPRPGDGLP
TH_2509|M.thermoresistible__bu --------------------------------------------------
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 LPDDPPVRVLRSGGRGPAAARNVGWRASRSRWVCFLDDDVLPDRDWISAL
TH_2509|M.thermoresistible__bu --------------------------------------------------
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 CLDLKAADACGAAGSQAVLEVPTPRRPSDDQRRTARLATAQWITADMAYR
TH_2509|M.thermoresistible__bu --------------------------------------------------
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 RDILVAAGGFDERFPRAYREDSDLALRIVSAGGTILRGERRCTHPVAPAT
TH_2509|M.thermoresistible__bu ----------------------------------------LTFDRESPQP
Rv3376|M.tuberculosis_H37Rv --MSISAVVFDRDGVLTSFD-----WTRAEEDV-------RRITGLPLEE
Mb3410|M.bovis_AF2122/97 --MSISAVVFDRDGVLTSFD-----WTRAEEDV-------RRITGLPLEE
Mflv_0023|M.gilvum_PYR-GCK -MTDLDAVLFDFSGTLFRLEEDESWFDGMTLDS----AGNRDVDEHVQAE
Mvan_0949|M.vanbaalenii_PYR-1 -MSDLQAVLFDYSGTLFRLEEDESWFAGMELDTPLSPDANREIDGHVQAE
MSMEG_1078|M.smegmatis_MC2_155 MVVMVKAVLFDFSGTLFRLEEDESWFEGMTVDE-------REVDGHVQAE
MAV_4086|M.avium_104 WRSSVRAQIGNRDNALMRRKHGRRWRTRIGEGPGRMPAHAATTAAGTAAL
TH_2509|M.thermoresistible__bu DRPGIRGVVFDKDGTLFDFTRTWTPWCEQLVGE----------LSGGDPG
: . : : ...* .
Rv3376|M.tuberculosis_H37Rv IERRWG-----------------------------------GWLN-GLTI
Mb3410|M.bovis_AF2122/97 IERRWG-----------------------------------GWLN-GLTI
Mflv_0023|M.gilvum_PYR-GCK LMRRLT-----------------------------------APTGRSVSM
Mvan_0949|M.vanbaalenii_PYR-1 LMRRLT-----------------------------------APTGHSVSM
MSMEG_1078|M.smegmatis_MC2_155 LMRRLT-----------------------------------APTGRSVQM
MAV_4086|M.avium_104 LAGLLGRRATARRAAALWLLCTIEFAARRWLSGPRNVREALGLSATSVLI
TH_2509|M.thermoresistible__bu LARRLG-----------------------------------AALGFDLEL
: . .: :
Rv3376|M.tuberculosis_H37Rv DDAFVETQPISEFLSSLAR-ELELGSKARDELVRLDYMAFAQ--------
Mb3410|M.bovis_AF2122/97 DDAFVETQPISEFLSSLAR-ELELGSKARDELVRLDYMAFAQ--------
Mflv_0023|M.gilvum_PYR-GCK TPEALEAWMKRDLAPHLHR-EAYLHVLRESGLACEHAESLYSRVIDPACW
Mvan_0949|M.vanbaalenii_PYR-1 TPDALDAWLNRDLAPHLHR-EAYLHVLRESGLAHHHAESLYSRVIDPACW
MSMEG_1078|M.smegmatis_MC2_155 SDEQYHAWVNRDLAPHLHR-EAYLHVLRESGLADPHAESLYGRVIDPDSW
MAV_4086|M.avium_104 PPVAVAHRLAGEWTFRRARPEPPLAVLLDRDDTLIVDRPYLN---DPAGV
TH_2509|M.thermoresistible__bu RMFEPDSVVLTDTIQAVVK--TLLGVLPPDTDADRLFRHVDDS-IATRSP
: : * .
Rv3376|M.tuberculosis_H37Rv -GYPDARPALEEARRRGLKVGVLTNNS-LLVSARSLLQCAALHDLVDVVL
Mb3410|M.bovis_AF2122/97 -GYPDARPALEEARRRGLKVGVLTNNS-LLVSARSLLQCAALHDLVDVVL
Mflv_0023|M.gilvum_PYR-GCK TPYPDTATVLTGLRRRGIRTAVVSN---IAFDLRPAFDGVG---TVDEFV
Mvan_0949|M.vanbaalenii_PYR-1 TPYPDTATVLDGLHRRGISTAVVSN---IAFDVRPAFEVLGAAGHVDEFV
MSMEG_1078|M.smegmatis_MC2_155 TAYPDTATVLKSLKQQDIKTAVVSN---IAFDVRPAFTALGIDADVDEFV
MAV_4086|M.avium_104 RPTYDAAKALTRLRRRGLLLAVVTNQSGVARGLISAGQLAAVNDRVDEVL
TH_2509|M.thermoresistible__bu AQVVPLRPLLERLRSAGIVLGLATNDQ--KKSTLRHLQQAGIDSCLSFVA
* : .: .: :* . . :. .
Rv3376|M.tuberculosis_H37Rv SSQM------------IGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADW
Mb3410|M.bovis_AF2122/97 SSQM------------IGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADW
Mflv_0023|M.gilvum_PYR-GCK LSFE------------VGAVKPDPSIFQTALDRLGVPAERALMVGDSDEA
Mvan_0949|M.vanbaalenii_PYR-1 LSFE------------VGAVKPDPAIFQTALDRLGVAADRALMVGDSDEA
MSMEG_1078|M.smegmatis_MC2_155 LSYE------------VGAVKPDAAIFTTTLQRLGVAPQDALMVGDSEEA
MAV_4086|M.avium_104 GPFDSWQVCVHGAADGCGCRKPRPGLILAAAEALGVPARRCVMIGDTGAD
TH_2509|M.thermoresistible__bu DADS------------GHGIKPGPGMLVAFCEHTGLSPQHCAMVGDSVFD
. ** . : : *:.. . :..*
Rv3376|M.tuberculosis_H37Rv VEGARCAGMRAYLVD--RSGQTRDG---VVRDLSSLGAILDGAGP-----
Mb3410|M.bovis_AF2122/97 VEGARCAGMRAYLVD--RSGQTRDG---VVRDLSSLGAILDGAGP-----
Mflv_0023|M.gilvum_PYR-GCK DGGARALGCAFALVDPLPTRERSDG---LLGALRAHGIRL----------
Mvan_0949|M.vanbaalenii_PYR-1 DGGARTLGCAFALVDPLPTAERKDG---LVAALWANGIQL----------
MSMEG_1078|M.smegmatis_MC2_155 DGGATAVGCAFALVDPLPTTERPDG---LIAAVSSVGIAT----------
MAV_4086|M.avium_104 VRAALAAGAAAVLVPTDRTLPAEVE---HARAHARVAATLNDAVSLVLSE
TH_2509|M.thermoresistible__bu MLAAQSANFLRIGVCSGPTPAERLXXXLLRTGRPWVPVCWHREHTSDRGG
.* . * :
Rv3376|M.tuberculosis_H37Rv -----
Mb3410|M.bovis_AF2122/97 -----
Mflv_0023|M.gilvum_PYR-GCK -----
Mvan_0949|M.vanbaalenii_PYR-1 -----
MSMEG_1078|M.smegmatis_MC2_155 -----
MAV_4086|M.avium_104 CR---
TH_2509|M.thermoresistible__bu RRGSR