For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SDLQAVLFDYSGTLFRLEEDESWFAGMELDTPLSPDANREIDGHVQAELMRRLTAPTGHSVSMTPDALDA WLNRDLAPHLHREAYLHVLRESGLAHHHAESLYSRVIDPACWTPYPDTATVLDGLHRRGISTAVVSNIAF DVRPAFEVLGAAGHVDEFVLSFEVGAVKPDPAIFQTALDRLGVAADRALMVGDSDEADGGARTLGCAFAL VDPLPTAERKDGLVAALWANGIQL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0949 | - | - | 100% (235) | HAD family hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3410 | - | 5e-09 | 33.61% (119) | hypothetical protein Mb3410 |
| M. gilvum PYR-GCK | Mflv_0023 | - | 1e-105 | 81.28% (235) | HAD family hydrolase |
| M. tuberculosis H37Rv | Rv3376 | - | 5e-09 | 33.61% (119) | hypothetical protein Rv3376 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4086 | - | 5e-07 | 32.77% (119) | transferase |
| M. smegmatis MC2 155 | MSMEG_1078 | - | 5e-91 | 73.04% (230) | hydrolase |
| M. thermoresistible (build 8) | TH_4652 | - | 6e-10 | 63.04% (46) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
TH_4652|M.thermoresistible__bu --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 MRHDDYTLVIPTVGRESLRRLLIALRESMGPQPPEVVVVDDRPRPGDGLP
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
TH_4652|M.thermoresistible__bu --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 LPDDPPVRVLRSGGRGPAAARNVGWRASRSRWVCFLDDDVLPDRDWISAL
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
TH_4652|M.thermoresistible__bu --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 CLDLKAADACGAAGSQAVLEVPTPRRPSDDQRRTARLATAQWITADMAYR
Mb3410|M.bovis_AF2122/97 --------------------------------------------------
Rv3376|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_0949|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_0023|M.gilvum_PYR-GCK --------------------------------------------------
TH_4652|M.thermoresistible__bu --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 --------------------------------------------------
MAV_4086|M.avium_104 RDILVAAGGFDERFPRAYREDSDLALRIVSAGGTILRGERRCTHPVAPAT
Mb3410|M.bovis_AF2122/97 --MSISAVVFDRDGVLTSFDW-----TRAEEDVRRITGLPLEE-----IE
Rv3376|M.tuberculosis_H37Rv --MSISAVVFDRDGVLTSFDW-----TRAEEDVRRITGLPLEE-----IE
Mvan_0949|M.vanbaalenii_PYR-1 -MSDLQAVLFDYSGTLF----------RLEEDESWFAGMELDTPLSPDAN
Mflv_0023|M.gilvum_PYR-GCK -MTDLDAVLFDFSGTLF----------RLEEDESWFDGMTLDS----AGN
TH_4652|M.thermoresistible__bu -------VLFDFSGTLF----------RLEEDASWFGGMTIAE------Q
MSMEG_1078|M.smegmatis_MC2_155 MVVMVKAVLFDFSGTLF----------RLEEDESWFEGMTVDE-------
MAV_4086|M.avium_104 WRSSVRAQIGNRDNALMRRKHGRRWRTRIGEGPGRMPAHAATT------A
: : ...* * *. : .
Mb3410|M.bovis_AF2122/97 RRWGGWLNGLTIDDAFVETQP----------------------ISEFLSS
Rv3376|M.tuberculosis_H37Rv RRWGGWLNGLTIDDAFVETQP----------------------ISEFLSS
Mvan_0949|M.vanbaalenii_PYR-1 REIDGHVQAELMRRLTAPTGHSVSMTPDALDAWLNRDLAPHLHREAYLHV
Mflv_0023|M.gilvum_PYR-GCK RDVDEHVQAELMRRLTAPTGRSVSMTPEALEAWMKRDLAPHLHREAYLHV
TH_4652|M.thermoresistible__bu REVDRHVQVELMR-------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 REVDGHVQAELMRRLTAPTGRSVQMSDEQYHAWVNRDLAPHLHREAYLHV
MAV_4086|M.avium_104 AGTAALLAGLLGRRATARRAAALWLLCTIEFAARRWLSGPRNVREALGLS
:
Mb3410|M.bovis_AF2122/97 LARELELGSKARDELV-----------------------------RLDYM
Rv3376|M.tuberculosis_H37Rv LARELELGSKARDELV-----------------------------RLDYM
Mvan_0949|M.vanbaalenii_PYR-1 LRESGLAHHHAESLYS-----------------------------RVIDP
Mflv_0023|M.gilvum_PYR-GCK LRESGLACEHAESLYS-----------------------------RVIDP
TH_4652|M.thermoresistible__bu --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 LRESGLADPHAESLYG-----------------------------RVIDP
MAV_4086|M.avium_104 ATSVLIPPVAVAHRLAGEWTFRRARPEPPLAVLLDRDDTLIVDRPYLNDP
Mb3410|M.bovis_AF2122/97 AFAQGYPDARPALEEARRRGLKVGVLTNNS-LLVSARSLLQCAALHDLVD
Rv3376|M.tuberculosis_H37Rv AFAQGYPDARPALEEARRRGLKVGVLTNNS-LLVSARSLLQCAALHDLVD
Mvan_0949|M.vanbaalenii_PYR-1 ACWTPYPDTATVLDGLHRRGISTAVVSN---IAFDVRPAFEVLGAAGHVD
Mflv_0023|M.gilvum_PYR-GCK ACWTPYPDTATVLTGLRRRGIRTAVVSN---IAFDLRPAFDGVG---TVD
TH_4652|M.thermoresistible__bu --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 DSWTAYPDTATVLKSLKQQDIKTAVVSN---IAFDVRPAFTALGIDADVD
MAV_4086|M.avium_104 AGVRPTYDAAKALTRLRRRGLLLAVVTNQSGVARGLISAGQLAAVNDRVD
Mb3410|M.bovis_AF2122/97 VVLSSQM------------IGAAKPDPRAYQAIAEALGVSTTSCLFFDDI
Rv3376|M.tuberculosis_H37Rv VVLSSQM------------IGAAKPDPRAYQAIAEALGVSTTSCLFFDDI
Mvan_0949|M.vanbaalenii_PYR-1 EFVLSFE------------VGAVKPDPAIFQTALDRLGVAADRALMVGDS
Mflv_0023|M.gilvum_PYR-GCK EFVLSFE------------VGAVKPDPSIFQTALDRLGVPAERALMVGDS
TH_4652|M.thermoresistible__bu --------------------------------------------------
MSMEG_1078|M.smegmatis_MC2_155 EFVLSYE------------VGAVKPDAAIFTTTLQRLGVAPQDALMVGDS
MAV_4086|M.avium_104 EVLGPFDSWQVCVHGAADGCGCRKPRPGLILAAAEALGVPARRCVMIGDT
Mb3410|M.bovis_AF2122/97 ADWVEGARCAGMRAYLVD--RSGQTRDGVVRDLSSLGAILDGAGP-----
Rv3376|M.tuberculosis_H37Rv ADWVEGARCAGMRAYLVD--RSGQTRDGVVRDLSSLGAILDGAGP-----
Mvan_0949|M.vanbaalenii_PYR-1 DEADGGARTLGCAFALVDPLPTAERKDGLVAALWANGIQL----------
Mflv_0023|M.gilvum_PYR-GCK DEADGGARALGCAFALVDPLPTRERSDGLLGALRAHGIRL----------
TH_4652|M.thermoresistible__bu -------------LVLVDPLPSGQRPDGLRTALRDHGLRV----------
MSMEG_1078|M.smegmatis_MC2_155 EEADGGATAVGCAFALVDPLPTTERPDGLIAAVSSVGIAT----------
MAV_4086|M.avium_104 GADVRAALAAGAAAVLVPTDRTLPAEVEHARAHARVAATLNDAVSLVLSE
** : .
Mb3410|M.bovis_AF2122/97 --
Rv3376|M.tuberculosis_H37Rv --
Mvan_0949|M.vanbaalenii_PYR-1 --
Mflv_0023|M.gilvum_PYR-GCK --
TH_4652|M.thermoresistible__bu --
MSMEG_1078|M.smegmatis_MC2_155 --
MAV_4086|M.avium_104 CR