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M. smegmatis MC2 155 MSMEG_1078 (-)

annotation: hydrolase
coordinates: 1142177 - 1142866
length: 229

VVMVKAVLFDFSGTLFRLEEDESWFEGMTVDEREVDGHVQAELMRRLTAPTGRSVQMSDEQYHAWVNRDL
APHLHREAYLHVLRESGLADPHAESLYGRVIDPDSWTAYPDTATVLKSLKQQDIKTAVVSNIAFDVRPAF
TALGIDADVDEFVLSYEVGAVKPDAAIFTTTLQRLGVAPQDALMVGDSEEADGGATAVGCAFALVDPLPT
TERPDGLIAAVSSVGIAT*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1078--100% (229)hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3410-6e-0727.73% (119) hypothetical protein Mb3410
M. gilvum PYR-GCKMflv_0023-8e-9072.93% (229) HAD family hydrolase
M. tuberculosis H37RvRv3376-6e-0727.73% (119) hypothetical protein Rv3376
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. thermoresistible (build 8)TH_4652-2e-1280.00% (40) PUTATIVE -
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0949-5e-9173.04% (230) HAD family hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0023|M.gilvum_PYR-GCK          -MTDLDAVLFDFSGTLF-----RLEEDESWFDGMTLDS----AGNRDVDE
Mvan_0949|M.vanbaalenii_PYR-1       -MSDLQAVLFDYSGTLF-----RLEEDESWFAGMELDTPLSPDANREIDG
MSMEG_1078|M.smegmatis_MC2_155      MVVMVKAVLFDFSGTLF-----RLEEDESWFEGMTVDE-------REVDG
TH_4652|M.thermoresistible__bu      -------VLFDFSGTLF-----RLEEDASWFGGMTIAE------QREVDR
Mb3410|M.bovis_AF2122/97            --MSISAVVFDRDGVLTSFDWTRAEEDVRRITGLPLEE-----IERRWGG
Rv3376|M.tuberculosis_H37Rv         --MSISAVVFDRDGVLTSFDWTRAEEDVRRITGLPLEE-----IERRWGG
                                           *:** .*.*      * ***   : *: :         *  . 

Mflv_0023|M.gilvum_PYR-GCK          HVQAELMRRLTAPTGRSVSMTPEALEAWMKRDLAPHLHREAYLHVLRESG
Mvan_0949|M.vanbaalenii_PYR-1       HVQAELMRRLTAPTGHSVSMTPDALDAWLNRDLAPHLHREAYLHVLRESG
MSMEG_1078|M.smegmatis_MC2_155      HVQAELMRRLTAPTGRSVQMSDEQYHAWVNRDLAPHLHREAYLHVLRESG
TH_4652|M.thermoresistible__bu      HVQVELMR------------------------------------------
Mb3410|M.bovis_AF2122/97            WLNGLTIDDAFVETQP----------------------ISEFLSSLAREL
Rv3376|M.tuberculosis_H37Rv         WLNGLTIDDAFVETQP----------------------ISEFLSSLAREL
                                     ::   :                                           

Mflv_0023|M.gilvum_PYR-GCK          LACEHAESLYSRVIDPACWTPYPDTATVLTGLRRRGIRTAVVSN--IAFD
Mvan_0949|M.vanbaalenii_PYR-1       LAHHHAESLYSRVIDPACWTPYPDTATVLDGLHRRGISTAVVSN--IAFD
MSMEG_1078|M.smegmatis_MC2_155      LADPHAESLYGRVIDPDSWTAYPDTATVLKSLKQQDIKTAVVSN--IAFD
TH_4652|M.thermoresistible__bu      --------------------------------------------------
Mb3410|M.bovis_AF2122/97            ELGSKARDELVRLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLVS
Rv3376|M.tuberculosis_H37Rv         ELGSKARDELVRLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLVS
                                                                                      

Mflv_0023|M.gilvum_PYR-GCK          LRPAFDGVG---TVDEFVLSFEVGAVKPDPSIFQTALDRLGVPAERALMV
Mvan_0949|M.vanbaalenii_PYR-1       VRPAFEVLGAAGHVDEFVLSFEVGAVKPDPAIFQTALDRLGVAADRALMV
MSMEG_1078|M.smegmatis_MC2_155      VRPAFTALGIDADVDEFVLSYEVGAVKPDAAIFTTTLQRLGVAPQDALMV
TH_4652|M.thermoresistible__bu      --------------------------------------------------
Mb3410|M.bovis_AF2122/97            ARSLLQCAALHDLVDVVLSSQMIGAAKPDPRAYQAIAEALGVSTTSCLFF
Rv3376|M.tuberculosis_H37Rv         ARSLLQCAALHDLVDVVLSSQMIGAAKPDPRAYQAIAEALGVSTTSCLFF
                                                                                      

Mflv_0023|M.gilvum_PYR-GCK          GDSDEADGGARALGCAFALVDPLPTRERSDGLLGALRAHGIRL-----
Mvan_0949|M.vanbaalenii_PYR-1       GDSDEADGGARTLGCAFALVDPLPTAERKDGLVAALWANGIQL-----
MSMEG_1078|M.smegmatis_MC2_155      GDSEEADGGATAVGCAFALVDPLPTTERPDGLIAAVSSVGIAT-----
TH_4652|M.thermoresistible__bu      ----------------LVLVDPLPSGQRPDGLRTALRDHGLRV-----
Mb3410|M.bovis_AF2122/97            DDIADWVEGARCAGMRAYLVD--RSGQTRDGVVRDLSSLGAILDGAGP
Rv3376|M.tuberculosis_H37Rv         DDIADWVEGARCAGMRAYLVD--RSGQTRDGVVRDLSSLGAILDGAGP
                                                      ***   : :  **:   :   *