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VRHDDYTLVIPTVGRESLRRLLIALRESMGPQPPEVVVVDDRPRPGDGLPLPDDPPVRVLRSGGRGPAAA RNVGWRASRSRWVCFLDDDVLPDRDWISALCLDLKAADACGAAGSQAVLEVPTPRRPSDDQRRTARLATA QWITADMAYRRDILVAAGGFDERFPRAYREDSDLALRIVSAGGTILRGERRCTHPVAPATWRSSVRAQIG NRDNALMRRKHGRRWRTRIGEGPGRMPAHAATTAAGTAALLAGLLGRRATARRAAALWLLCTIEFAARRW LSGPRNVREALGLSATSVLIPPVAVAHRLAGEWTFRRARPEPPLAVLLDRDDTLIVDRPYLNDPAGVRPT YDAAKALTRLRRRGLLLAVVTNQSGVARGLISAGQLAAVNDRVDEVLGPFDSWQVCVHGAADGCGCRKPR PGLILAAAEALGVPARRCVMIGDTGADVRAALAAGAAAVLVPTDRTLPAEVEHARAHARVAATLNDAVSL VLSECR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4086 | - | - | 100% (496) | transferase |
| M. avium 104 | MAV_1120 | - | 3e-16 | 35.48% (186) | hypothetical protein MAV_1120 |
| M. avium 104 | MAV_4475 | - | 4e-11 | 35.00% (200) | membrane sugar transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0118 | - | 3e-12 | 31.55% (168) | dehydratase |
| M. gilvum PYR-GCK | Mflv_5057 | - | 9e-10 | 31.03% (203) | glycosyl transferase family protein |
| M. tuberculosis H37Rv | Rv0114 | gmhB | 3e-12 | 31.93% (166) | D-alpha,beta-D-heptose-1,7-biphosphate phosphatase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3831c | - | 6e-11 | 32.34% (201) | putative glycosyltransferase |
| M. marinum M | MMAR_1024 | - | 6e-10 | 32.02% (203) | membrane glycosyl transferase |
| M. smegmatis MC2 155 | MSMEG_1426 | - | 2e-12 | 33.50% (203) | membrane sugar transferase |
| M. thermoresistible (build 8) | TH_1903 | - | 5e-11 | 32.09% (268) | PROBABLE MEMBRANE SUGAR TRANSFERASE |
| M. ulcerans Agy99 | MUL_0776 | - | 5e-09 | 31.03% (203) | membrane glycosyl transferase |
| M. vanbaalenii PYR-1 | Mvan_1299 | - | 1e-10 | 33.50% (203) | glycosyl transferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5057|M.gilvum_PYR-GCK MTGP------------RLPDGFAVQVDRRVRVLGEGAALLGGSPTRLLRL
Mvan_1299|M.vanbaalenii_PYR-1 MTGP------------RLPDGFAVQVDRRVRVLGEGAALLGGSPTRLLRL
MSMEG_1426|M.smegmatis_MC2_155 MTGP------------RLPDGFAVQVDRRVKVLGEGAALLGGSPTRLLRL
TH_1903|M.thermoresistible__bu MTGQ------------RLPDGFAVQVDRRVKVLGEGAALLGGSPTRLLKL
MMAR_1024|M.marinum_M MTQP------------RLPDGFAVQVDRRVRVLGGGSALLGGSPTRLLRL
MUL_0776|M.ulcerans_Agy99 MTQP------------RLPDGFAVQVDRRVRVLGGGSALLGGSPTRLLRL
MAB_3831c|M.abscessus_ATCC_199 MTTSDEQAQHAAPSQERLPDGFAVQVDRRVRVLDEGSALLGGSPTRLLRL
Mb0118|M.bovis_AF2122/97 --------------------------------------------------
Rv0114|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4086|M.avium_104 --------------MRHDDYTLVIPTVGRESLRRLLIALRESMGPQPPEV
Mflv_5057|M.gilvum_PYR-GCK APAAQTMLHGGRLEVHDAVSAQLAR-----TLLDATVAHPRPLSGPSHRD
Mvan_1299|M.vanbaalenii_PYR-1 APAAQTMLHGGRLEVHDAVSAQLAR-----TLLDATVAHPRPMSGPSHRD
MSMEG_1426|M.smegmatis_MC2_155 APTAQNMLSGGRLEVHDAVSAQLAR-----TLLDATVAHPRPASGPSHLD
TH_1903|M.thermoresistible__bu APAARTMLAGGRLEVRDAVSAQLAR-----TLLDATVAHPRPASGPSHRD
MMAR_1024|M.marinum_M APAAQDMLCDGRLKVRDDISAELAR-----TLLDATVAHPRPASGPSHRD
MUL_0776|M.ulcerans_Agy99 APAAQDMLCDGRLKVRDDISAELAR-----TLLDATVAHPRPASGPSHRD
MAB_3831c|M.abscessus_ATCC_199 APAARTLLSGGRLEVRDATSAQLAR-----TLLDATVAHPRPVGGPGYRD
Mb0118|M.bovis_AF2122/97 --------------------------------------------------
Rv0114|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4086|M.avium_104 VVVDDRPRPGDGLPLPDDPPVRVLRSGGRGPAAARNVGWRASRSRWVCFL
Mflv_5057|M.gilvum_PYR-GCK VTVVIPVHNNATGLTRLVAALRGLKVVIVDDGSSRPVNEADFASAACDIR
Mvan_1299|M.vanbaalenii_PYR-1 VTVIIPVRDNLSGLTRLVSALRGLRVVVVDDGSAVPVAESDFAATRCDVQ
MSMEG_1426|M.smegmatis_MC2_155 VTVVVPVRDNASGLHRLMAALRGLRVIVVDDGSAIPVQPSDFSGMHCDVQ
TH_1903|M.thermoresistible__bu VTVVIPVRDNAFGLHRLMRALRGLRVIIVDDGSAVPVDAAEFTGLHCDVQ
MMAR_1024|M.marinum_M VTVVIPVRDNASGVRRLVASLRGLRVIVVDDGSSSPVELEDFAGAHCDVE
MUL_0776|M.ulcerans_Agy99 VTVVISVRDNASGVRRLVASLRGLRVIVVDDGSSSPVELEDFAGAHCDIE
MAB_3831c|M.abscessus_ATCC_199 VTVVIPCRDNGFGLRRLLRALRGMRVIVVDDGSTIPIVESDLEGMHCHVE
Mb0118|M.bovis_AF2122/97 --------------------------------------------------
Rv0114|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4086|M.avium_104 DDDVLPDRDWISALCLDLKAADACGAAGSQAVLEVPTPRRPSDDQRRTAR
Mflv_5057|M.gilvum_PYR-GCK VLRHSRRKGPSAARNAGLAVCATDFVAFLDSD------VVPRKGWLEALL
Mvan_1299|M.vanbaalenii_PYR-1 VLRNDRSKGPAAARNAGLAVCTTDLVAFLDSD------VLPRRGWLEALL
MSMEG_1426|M.smegmatis_MC2_155 VLRHTRSNGPAAARNTGLASCETDFVAFLDSD------VVPKRGWLEALL
TH_1903|M.thermoresistible__bu VLRHPHSKGPAAARNTGLAACTTDFVAFLDSD------VVPQRGWLEALL
MMAR_1024|M.marinum_M VLHHRRSKGPAAARNTGLAACTTEFVAFLDSD------VAPRRGWLEALL
MUL_0776|M.ulcerans_Agy99 VLHHRRSKGPAAARNTGLAACTTEFVAFLDSD------VAPRRGWLEALL
MAB_3831c|M.abscessus_ATCC_199 VVRHADSQGPAAARNTGLKLATTDFVAFLDSD------VVPRRGWLEALL
Mb0118|M.bovis_AF2122/97 ---------MVAER------AGHQWCLFLDRD------GVINRQVVGDYV
Rv0114|M.tuberculosis_H37Rv ---------MVAER------AGHQWCLFLDRD------GVINRQVVGDYV
MAV_4086|M.avium_104 LATAQWITADMAYRRDILVAAGGFDERFPRAYREDSDLALRIVSAGGTIL
* * . * :
Mflv_5057|M.gilvum_PYR-GCK GHFCDPAVALVAPRIVAHEPSDNVVARYEAVRSSLDLGLREAPVIPFGTV
Mvan_1299|M.vanbaalenii_PYR-1 GHFCDPAVALVAPRIVALNQSDNVVARYEAVRSSLDLGLREAPVIPYGTV
MSMEG_1426|M.smegmatis_MC2_155 GHFCDPAVALVAPRIVGLHNADNIVARYESVRSSLDLGVREAPVVPHGTV
TH_1903|M.thermoresistible__bu GHFCDPAVALVAPRIVGLRKDDNLIARYEAVRSSLDLGVREAPVVPYGPV
MMAR_1024|M.marinum_M GHFCDPTVALVAPRIVGLAPSENLVARYEAVRSSLDLGQREAPILPHSPV
MUL_0776|M.ulcerans_Agy99 GHFCDPTVALVAPRIVGLAPSENLVARYEAVRSSLDLGQREAPILPHSPV
MAB_3831c|M.abscessus_ATCC_199 GHFSDPAVALVAPRIVGLVLSDNAIARYEAVRSSLDLGLREAPVVPYGPV
Mb0118|M.bovis_AF2122/97 RNWR--QFEWLPGAARALKKLRAWAPYIVVVTNQQGVG-----------A
Rv0114|M.tuberculosis_H37Rv RNWR--QFEWLPGAARALKKLRAWAPYIVVVTNQQGVG-----------A
MAV_4086|M.avium_104 RGERRCTHPVAPATWRSSVRAQIGNRDNALMRRKHGRRWRTRIGEGPGRM
. . : . .
Mflv_5057|M.gilvum_PYR-GCK SYVPSAAIICRRSAILEIGGFDETLVSGEDVDLCWRLNESGARLRYEPIA
Mvan_1299|M.vanbaalenii_PYR-1 SYVPSAAIICRRSRLLEVGGFDESLISGEDVDLCWRLNEAGARLRYEPIA
MSMEG_1426|M.smegmatis_MC2_155 SYVPSAAIICRRSALVEVGGFDETMHSGEDVDLCWRLVESGARLRYEPIA
TH_1903|M.thermoresistible__bu SYVPSAAIICRRKVLDEIGGFDEALRSGEDVDLCWRLVEAGTRLRYEPIA
MMAR_1024|M.marinum_M SYVPSAAIICRCSAIRQVGGFDETMHSGEDVDLCWRLIESGARLRYEPIA
MUL_0776|M.ulcerans_Agy99 SYVPSAAIICRCSAIRQVGGFDETMHSGEDVDLCWRLIESGARLRYEPIA
MAB_3831c|M.abscessus_ATCC_199 SYVPSAAIVVRRSAINEIGGFDEALQCGEDVDLCWRLIEAGSRLRYEPVS
Mb0118|M.bovis_AF2122/97 GLMSAVDVMVIHRHLQMQLASDGVLIDGFQVCPHHRSQRCGCRK------
Rv0114|M.tuberculosis_H37Rv GLMSAVDVMVIHRHLQMQLASDGVLIDGFQVCPHHRSQRCGCRK------
MAV_4086|M.avium_104 PAHAATTAAGTAALLAGLLGRRATARRAAALWLLCTIEFAARRWLSGPRN
.:. : . . : .. *
Mflv_5057|M.gilvum_PYR-GCK MVGHDHRTELRKWFARKSFYGGSAAPLTIRHPGKTAPLVISG----WMLV
Mvan_1299|M.vanbaalenii_PYR-1 MVAHDHRTELRKWFARKSFYGSSAAPLTIRHPGKTAPLVISG----WTLV
MSMEG_1426|M.smegmatis_MC2_155 LVAHDHRTNLRAWFHRKAFYGTSAAPLTVRHPGKTSPLVISG----WTLM
TH_1903|M.thermoresistible__bu LVAHDHRTDIGEWLGRKAFYGSSAAPLTARHPDKTAPLLMSG----WTLV
MMAR_1024|M.marinum_M LVGHEHRTQLRAWIARKAFYGGSAAPLSVRHPDKTAPLVISG----WALT
MUL_0776|M.ulcerans_Agy99 LVGHEHRTQLRAWIARKAFYGGSAAPLSVRHPDKTAPLVISG----WALT
MAB_3831c|M.abscessus_ATCC_199 HVAHDHRLTLREWFARKAFYGKSAAPLSTRHPDKVAPMVISR----WTLL
Mb0118|M.bovis_AF2122/97 ----PRPGLVLDWLR--------------RHPDSEPLLSIV---------
Rv0114|M.tuberculosis_H37Rv ----PRPGLVLDWLG--------------RHPDSEPLLSIV---------
MAV_4086|M.avium_104 VREALGLSATSVLIPPVAVAHRLAGEWTFRRARPEPPLAVLLDRDDTLIV
: *:. . : :
Mflv_5057|M.gilvum_PYR-GCK VWMLVAVGSGIGYAASVAVAAVTGRRIAKSLSTVQTEPMEVAVVAAHGLW
Mvan_1299|M.vanbaalenii_PYR-1 VWMLVAIGSGIGYFASIAVAAITGRRIAKSLASVQTEPMEVAVVAAHGLG
MSMEG_1426|M.smegmatis_MC2_155 VWLMLGVGSFFGYLASLAAAVFAGTRIARALSVVETEPKEVAVVAAHGLW
TH_1903|M.thermoresistible__bu LGVLVAMGSWVGYLAALVLAVITGRRVAKSLSTVGSEPVEVVALAAQGLG
MMAR_1024|M.marinum_M AWVLMSLGTRATQLASLIIAVLTGRRIATALRSAQTSSWDVVVVAARGLW
MUL_0776|M.ulcerans_Agy99 AWVLLSLGTRATQLASLIIAVLTGRRIATALRSAQTSSWDVVVVAARGLW
MAB_3831c|M.abscessus_ATCC_199 VWILAAVGSGMGYLAAVGMAALAAGRVARTLRGVDTPPRDVVRVAAQGVG
Mb0118|M.bovis_AF2122/97 --------------------------VGDSLSDLELAHN----VAAAAGA
Rv0114|M.tuberculosis_H37Rv --------------------------VGDSLSDLELAHN----VAAAAGA
MAV_4086|M.avium_104 DRPYLNDPAGVRPTYDAAKALTRLRRRGLLLAVVTNQSGVARGLISAGQL
. * : : .
Mflv_5057|M.gilvum_PYR-GCK SAALQLASALCRHYWPIALVAS-------VLSKRCRRVVVVAAVLDGVFD
Mvan_1299|M.vanbaalenii_PYR-1 SAALQLASAICRHYWPIALIAA-------LVSRRSRRVVVVAAVLDGVFD
MSMEG_1426|M.smegmatis_MC2_155 SSALQLCSAICRHYWPIAMIAA-------VLFRRARHAVLVAAVVDGVVD
TH_1903|M.thermoresistible__bu SAARQLAGAICRHYWPIALIAA-------LLSPRFRQVVVVAAVVDGVVD
MMAR_1024|M.marinum_M SAALQLASAICRHYWPVTLIAV-------IVSRHCRRVVLVAAVIDGVVD
MUL_0776|M.ulcerans_Agy99 SAALQLASAICRHYWPVTLIAV-------IVSRHCRRVVLVAAVIDGVVD
MAB_3831c|M.abscessus_ATCC_199 GAALQIASALCRHYWPLALFAA-------ALSRRSRQVLVVAAIVDGVVD
Mb0118|M.bovis_AF2122/97 CASVQIGGASSGG--------------------------VADASFDSLWE
Rv0114|M.tuberculosis_H37Rv CASVQIGGASSGG--------------------------VADASFDSLWE
MAV_4086|M.avium_104 AAVNDRVDEVLGPFDSWQVCVHGAADGCGCRKPRPGLILAAAEALGVPAR
: : . . ..
Mflv_5057|M.gilvum_PYR-GCK WVTRNGNADEDTKRVGILTYILLKRLDDIAYGLGLWSGVVRERHAGALKP
Mvan_1299|M.vanbaalenii_PYR-1 WVTRNGNADEDTKRVGLPTYLLLKRLDDIAYGLGLWTGVVRERHAGALKP
MSMEG_1426|M.smegmatis_MC2_155 WVTRRGNADDDTKPVGLLTHIVLKRLDDIAYGTGLWTGVVRERHLGALKP
TH_1903|M.thermoresistible__bu WLSRREHAGEDTKPVGLFAYLVLKRLDDLAYGCGLWAGVLRERDLGALKP
MMAR_1024|M.marinum_M WLRRREDPDGDSEPIGLLTYLLLKRIDDLAYGLGLWYGVMRERNAGALKP
MUL_0776|M.ulcerans_Agy99 WLRRREDPDGDSEPIGLLTYLLLKRIDDLAYGLGLWYGVMRERNAGALKP
MAB_3831c|M.abscessus_ATCC_199 WMKRNDSSASPDDRIGLIEYVLLKRLDDIAYGIGLWSGIVRERDLGALRP
Mb0118|M.bovis_AF2122/97 FAVAVGHARGERG-------------------------------------
Rv0114|M.tuberculosis_H37Rv FAVAVGHARGERG-------------------------------------
MAV_4086|M.avium_104 RCVMIGDTGADVRAALAAGAAAVLVPTDRTLPAEVEHARAHARVAATLND
.
Mflv_5057|M.gilvum_PYR-GCK QIRA------
Mvan_1299|M.vanbaalenii_PYR-1 QIRT------
MSMEG_1426|M.smegmatis_MC2_155 QVRS------
TH_1903|M.thermoresistible__bu QIRI------
MMAR_1024|M.marinum_M QIRR------
MUL_0776|M.ulcerans_Agy99 QIRR------
MAB_3831c|M.abscessus_ATCC_199 ELRP------
Mb0118|M.bovis_AF2122/97 ----------
Rv0114|M.tuberculosis_H37Rv ----------
MAV_4086|M.avium_104 AVSLVLSECR