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MANWYRPNYPEVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMFDAYLAERAERTGEKFVPFDPA ADYHTYVDGKKREDGVRSFLSSRAIEIPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRY LEAVTAAGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSFLRAAELLGVTPDAA AVFEDALSGVAAGRAGNFAVVVGINRTGRAAQAAQLRRHGADVVVTDLAELL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3400 | - | - | 100% (262) | PROBABLE HYDROLASE |
| M. tuberculosis H37Rv | Rv2006 | otsB1 | 1e-28 | 34.87% (238) | trehalose-6-phosphate phosphatase OtsB1 |
| M. tuberculosis H37Rv | Rv3372 | otsB2 | 4e-07 | 46.88% (64) | trehalose 6-phosphate phosphatase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3433 | - | 1e-148 | 100.00% (262) | hydrolase |
| M. gilvum PYR-GCK | Mflv_1072 | - | 9e-85 | 63.39% (254) | beta-phosphoglucomutase family hydrolase |
| M. leprae Br4923 | MLBr_00393 | - | 1e-110 | 74.43% (262) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_2130 | - | 3e-13 | 28.39% (236) | putative hydrolase |
| M. marinum M | MMAR_1144 | - | 1e-112 | 80.97% (247) | hydrolase |
| M. avium 104 | MAV_4350 | - | 1e-114 | 78.41% (264) | beta-phosphoglucomutase hydrolase |
| M. smegmatis MC2 155 | MSMEG_4183 | - | 1e-10 | 29.86% (211) | phosphoglycolate phosphatase, chromosomal |
| M. thermoresistible (build 8) | TH_2142 | - | 2e-98 | 72.47% (247) | PROBABLE HYDROLASE |
| M. ulcerans Agy99 | MUL_0908 | - | 3e-70 | 85.03% (147) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_5751 | - | 3e-85 | 66.80% (247) | beta-phosphoglucomutase family hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1072|M.gilvum_PYR-GCK ------------MKGDMLGLPDRIHACLFDLDGVLTDTASVHRRAWKAMF
Mvan_5751|M.vanbaalenii_PYR-1 ----------------MLGLPDRIRACLFDLDGVLTDTASVHRRAWKAMF
TH_2142|M.thermoresistible__bu ----------------VLGLPDHIRACLFDLDGVLTDTAGVHRKAWKAMF
Rv3400|M.tuberculosis_H37Rv MANWYRPNYP-EVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
Mb3433|M.bovis_AF2122/97 MANWYRPNYP-EVRSRVLGLPEKVRACLFDLDGVLTDTASLHTKAWKAMF
MMAR_1144|M.marinum_M ----------------MLGLPEKVRACLFDLDGVLTDTASVHTKAWKAMF
MUL_0908|M.ulcerans_Agy99 ----------------MLGLPEKVRACLFDLDGVLTDTASVHTKAWKAMF
MAV_4350|M.avium_104 MVEWIPPDPNHRKRVPVLGLPEKVHACLFDLDGVLTDTASVHTKAWKAMF
MLBr_00393|M.leprae_Br4923 MANWDHPTSK--VRSTVLGLPEQVRACLFDLDGVLTDTASVHAKAWQTMF
MAB_2130|M.abscessus_ATCC_1997 -----------------------MRAVLWDMDGTLIESE----KLWDISM
MSMEG_4183|M.smegmatis_MC2_155 -----------------------MLAVLWDMDGTLVDSE----KLWDISM
: * *:*:**.* :: : *. :
Mflv_1072|M.gilvum_PYR-GCK DEYLSDIADGAEDPDARYTPFDAGADYETYVDGKPRADGIRSFLGSRLID
Mvan_5751|M.vanbaalenii_PYR-1 DEYLRSRAEDG----VPYVPFDAGADYERYVDGKPRLDGIRSFLGSRGIV
TH_2142|M.thermoresistible__bu DEYLRDRAARTG---AEFVPFDIDADYHHYVDGKKREDGVRSFLASRSIK
Rv3400|M.tuberculosis_H37Rv DAYLAERAERTG---EKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
Mb3433|M.bovis_AF2122/97 DAYLAERAERTG---EKFVPFDPAADYHTYVDGKKREDGVRSFLSSRAIE
MMAR_1144|M.marinum_M DAYLSERAERTG---GQFVPFDPAADYRQYVDGKKREDGVRSFLSSRGIQ
MUL_0908|M.ulcerans_Agy99 DAYLSERAERTG---GQFVPFDPAADYRQYVDGKKREDGVRSFLSSRGIQ
MAV_4350|M.avium_104 DAYLADRAKRTG---ETFVPFDPAADYRKYVDGKKREDGVRSFLQSRGIH
MLBr_00393|M.leprae_Br4923 DTYLYQRAKHTG---ENFVPFDPTADYRQYVDGKKREDGVRSFLGSRGIT
MAB_2130|M.abscessus_ATCC_1997 GELCRKLG------------GEMTPELRTALVGGAADATMRMIFTALELE
MSMEG_4183|M.smegmatis_MC2_155 HALYARMG------------AVLTPEVRESTVGGSSETVMRIVYEDIGLE
. .: . * :* . :
Mflv_1072|M.gilvum_PYR-GCK VDE---------ATVTRLGDRKNEMFRKTLKSDGIEVFDGSRRYLQAAAD
Mvan_5751|M.vanbaalenii_PYR-1 APD---------ETVTLLGDRKNHVFTQTLHTDGVTVFEGSRRYLQAAAA
TH_2142|M.thermoresistible__bu LPDGHYDDDPATETVHGLGNRKNVVFHQILEAEGVEVFEGSRRYLAAVVD
Rv3400|M.tuberculosis_H37Rv IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
Mb3433|M.bovis_AF2122/97 IPDGSPDDPGAAETVYGLGNRKNDMLHKLLRDDGAQVFDGSRRYLEAVTA
MMAR_1144|M.marinum_M LPDGSPDDPGDLETVYGLGNRKNDMFQKVLKKDGVDVFEGSRRYLEAVSA
MUL_0908|M.ulcerans_Agy99 LPDGSPDDPGDLETVYGLGNRKNDMFQKVLKKDGVDVFEGSRRYLEAVSA
MAV_4350|M.avium_104 LPDGSPDDAGDAETIYGLGNRKNDMFQKVLKQDGVKVFDGSRRYLEAASA
MLBr_00393|M.leprae_Br4923 LPEGSADNSGDVETIYGLGNRKDDLFRQVLKEHGIEVFDGSRRYLEAITY
MAB_2130|M.abscessus_ATCC_1997 PDP----------VRMASENDWLHQYTGELFATGLIWCDGAQEMLGQLAA
MSMEG_4183|M.smegmatis_MC2_155 PDP----------AAMAESADWLHAYTGELFEQGLPWRPGAQEMLDALVA
. * * *::. *
Mflv_1072|M.gilvum_PYR-GCK AGLRRAVVSSSANTREVLELTGLDRYVEVRVDGVTLREENLPGKPAPDTY
Mvan_5751|M.vanbaalenii_PYR-1 AGLRRAVVSSSANTRTILELTGLDVYVEARVDGVTLREEHLPGKPAPDAF
TH_2142|M.thermoresistible__bu AGLGVAVVTSSANGRQILEVTGLDRFVQYRVDGVTMREEQLPGKPAPDSF
Rv3400|M.tuberculosis_H37Rv AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
Mb3433|M.bovis_AF2122/97 AGLGVAVVSSSANTRDVLATTGLDRFVQQRVDGVTLREEHIAGKPAPDSF
MMAR_1144|M.marinum_M AGLSIAVVSSSANTRDVLEITGLGRFIQQRVDGVRLREEHIAGKPAPDSY
MUL_0908|M.ulcerans_Agy99 AGLSIAVVSSSANTRDPSTCT-----------------------------
MAV_4350|M.avium_104 AGLGIAVVSSSANTRDVLEVTGLDRFVQQRVDGITLREEHLAGKPAPDSF
MLBr_00393|M.leprae_Br4923 AGLGVAVVSSSTNTRDVLKITGLDRFVQQQVDGITLREEHIAGKPAPDSY
MAB_2130|M.abscessus_ATCC_1997 EQMPMALVT---NTIRSLTDQALKTIGTHWFTESVCGDEVPAGKPAPDPY
MSMEG_4183|M.smegmatis_MC2_155 AEVPMALVT---NTRRDLAERALNSIGRHYFSVSVCGDEVPSGKPAPDPY
: *:*: *
Mflv_1072|M.gilvum_PYR-GCK LRAAELLGVDPAEAAVFEDALSGVAAGRAGDFGLVVGVDRTG--------
Mvan_5751|M.vanbaalenii_PYR-1 LRAAELLGVAPADAAVFEDALSGVAAGRAGGFGLVVGVDRTG--------
TH_2142|M.thermoresistible__bu LRAAELLQVPPQHGAVFEDALSGVAAGRAGGFGLVVGVDRVG--------
Rv3400|M.tuberculosis_H37Rv LRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVGINRTGRAA-----
Mb3433|M.bovis_AF2122/97 LRAAELLGVTPDAAAVFEDALSGVAAGRAGNFAVVVGINRTGRAA-----
MMAR_1144|M.marinum_M LRGAQLLDTAPDAAAVFEDAISGVQAGRAGNFGYVVGVDRVG--------
MUL_0908|M.ulcerans_Agy99 -----MANCSP---------MS----------AFSICVPRRV--------
MAV_4350|M.avium_104 LRGAQLLDVPAGAAAVFEDALSGVAAGRAGNFGFVVGVDRVG--------
MLBr_00393|M.leprae_Br4923 LRGAQLLDVAPDAAAVFEDALSGVQAGLSGHFGFVVGINRTGRVD-----
MAB_2130|M.abscessus_ATCC_1997 LRAAALLGVEPRDCLAIEDSVTGAAAAEAAGCAVLVVPNHVEVPAGARRR
MSMEG_4183|M.smegmatis_MC2_155 LRAAELLGVPVARCLAVEDSVTGTTAAEAAGCPVLVIPNDVAVPHGPRRK
: :: :
Mflv_1072|M.gilvum_PYR-GCK QAQALRDKGADIVITDLGELLT-------
Mvan_5751|M.vanbaalenii_PYR-1 QSEALRRNGADIVVTDLGELLSP------
TH_2142|M.thermoresistible__bu QAEALRRNGADIVVTDLAELLTP------
Rv3400|M.tuberculosis_H37Rv QAAQLRRHGADVVVTDLAELL--------
Mb3433|M.bovis_AF2122/97 QAAQLRRHGADVVVTDLAELL--------
MMAR_1144|M.marinum_M QAEDLRRNGADVVITDLAELLQS------
MUL_0908|M.ulcerans_Agy99 PALLISR----LVSWGIVD----------
MAV_4350|M.avium_104 QAEDLRRNGADVVVSDLAELLAS------
MLBr_00393|M.leprae_Br4923 QAEELRRIGANVVVTDLAELL--------
MAB_2130|M.abscessus_ATCC_1997 HAASLSGLSVRDLRDAHADVLAATTCKPI
MSMEG_4183|M.smegmatis_MC2_155 QVESLSLLGVDDLRAIHAELGPERLSA--
: : :