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M. marinum M MMAR_1294 (-)

annotation: TetR family transcriptional regulator
coordinates: 1577096 - 1577746
length: 216

VIDTNSFAKRDIVGPVKRVPYAEASRVLLRDSVLDAMRDLLLTRDWSAITLSDVARSAGISRQTIYNEFG
SRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGESAADPLVISLLTGVAKPDLLQLIT
TDSAPIITRASARLATAFTQTWVATSDDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERH
GVINVP
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_1294--100% (216)TetR family transcriptional regulator
M. marinum MMMAR_3519-1e-3943.46% (191) TetR family transcriptional regulator
M. marinum MMMAR_3158-3e-1929.51% (183) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3277c-1e-10392.16% (204) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_4718-7e-8574.29% (210) TetR family transcriptional regulator
M. tuberculosis H37RvRv3249c-1e-10392.16% (204) TetR family transcriptional regulator
M. leprae Br4923MLBr_00064-2e-0535.71% (70) putative transcriptional regulator
M. abscessus ATCC 19977MAB_3596c-3e-7165.33% (199) TetR family transcriptional regulator
M. avium 104MAV_4212-4e-9486.00% (200) putative transcriptional regulatory protein
M. smegmatis MC2 155MSMEG_1842-2e-8573.49% (215) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0467-1e-8580.71% (197) POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99MUL_2593-1e-11799.54% (216) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1745-4e-8677.78% (198) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1294|M.marinum_M               ----------------------------------MIDTNSFAKRDIVGPV
MUL_2593|M.ulcerans_Agy99           ---------------MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPV
Mb3277c|M.bovis_AF2122/97           -----------------------------------MSTPSAT----VAPV
Rv3249c|M.tuberculosis_H37Rv        -----------------------------------MSTPSAT----VAPV
MAV_4212|M.avium_104                -------------------------------------------------M
Mflv_4718|M.gilvum_PYR-GCK          -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
Mvan_1745|M.vanbaalenii_PYR-1       -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
TH_0467|M.thermoresistible__bu      ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155      MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
MAB_3596c|M.abscessus_ATCC_199      -MTDVLP--------------GRDALTSASVPARLPGVTRPDALRAGGSS
MLBr_00064|M.leprae_Br4923          --------------------------------------MINSTAGQTSQS
                                                                                      

MMAR_1294|M.marinum_M               KRVPYAEASRVLLRDSVLDAMRDLLLTRDWSAITLSDVARSAGISRQTIY
MUL_2593|M.ulcerans_Agy99           KRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIY
Mb3277c|M.bovis_AF2122/97           KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Rv3249c|M.tuberculosis_H37Rv        KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MAV_4212|M.avium_104                KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
Mflv_4718|M.gilvum_PYR-GCK          KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1       KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu      KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155      QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
MAB_3596c|M.abscessus_ATCC_199      HRVPYAEAARALLRESVLDALGDLLRQRDWSAVTMSDVSRRAGVSRQTLY
MLBr_00064|M.leprae_Br4923          RSRRSTRPSGDDRELAILATAEQLLEDRPLTEISVDYLAKSAGISRPTFY
                                    :    :..:    . ::*    ::*  *  : :::  ::: **:** *:*

MMAR_1294|M.marinum_M               NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MUL_2593|M.ulcerans_Agy99           NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
Mb3277c|M.bovis_AF2122/97           NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Rv3249c|M.tuberculosis_H37Rv        NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MAV_4212|M.avium_104                NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
Mflv_4718|M.gilvum_PYR-GCK          NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
Mvan_1745|M.vanbaalenii_PYR-1       NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu      NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155      NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
MAB_3596c|M.abscessus_ATCC_199      NEFGSRQGLAQGYALRLAHRLVDAVGDAIYAHVGDIHGALHSGFADFFAE
MLBr_00064|M.leprae_Br4923          FYFASKEAVLLTLLDRVFNKANAALETLIKNRDNKRGNKWRTGINVFFET
                                      *.*::.:      *: .:    :   :  . ..       .:  **  

MMAR_1294|M.marinum_M               SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MUL_2593|M.ulcerans_Agy99           SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
Mb3277c|M.bovis_AF2122/97           SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
Rv3249c|M.tuberculosis_H37Rv        SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
MAV_4212|M.avium_104                AAADPLVTSLRTGVAKPDLLQLITTDSAVIITRASARLASALTHTWVSTT
Mflv_4718|M.gilvum_PYR-GCK          SAADPLVISLLTGSSKPDLLQLITTDSAPIINHCSSRLTESLMGSWVRCS
Mvan_1745|M.vanbaalenii_PYR-1       SAADPLVISLLTGTSKPDLLQLITTDSAPIINHCSSRLTESFMSSWVRVS
TH_0467|M.thermoresistible__bu      SAADPLVISLLTGSAKPDLLQLITTDSAPIITRASQRLTESFQSSWVRAS
MSMEG_1842|M.smegmatis_MC2_155      SAADPLVISLLTGAAKPDLLQIITIGSGPIITRCSERLTATFQSSWIKAS
MAB_3596c|M.abscessus_ATCC_199      SAADPMVISLLTGEAKPELMRIVTVDSALIVVPASARLTESFMNSWVAAS
MLBr_00064|M.leprae_Br4923          FGSHKAVTCAGQVTRDNTEVRKLWSTFMQKWISYTAAVIDAERKRGVAPD
                                     .:.  * .      .   :: :           :  :  :     :   

MMAR_1294|M.marinum_M               DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MUL_2593|M.ulcerans_Agy99           DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
Mb3277c|M.bovis_AF2122/97           DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Rv3249c|M.tuberculosis_H37Rv        DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
MAV_4212|M.avium_104                DEDAGVLARAIVRLALSYVSMPPEADHDVAADLARLMTPFAERHGVVNVG
Mflv_4718|M.gilvum_PYR-GCK          EEDAGVLSRAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVVADP
Mvan_1745|M.vanbaalenii_PYR-1       QEDAGVLARAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVIDP-
TH_0467|M.thermoresistible__bu      EEDAGVLARAIVRLAMSYVSMPPEADHDVAHDLARLMTPFAERYGVIEEV
MSMEG_1842|M.smegmatis_MC2_155      DDDAGVLARAIVRLAMSYVSMPPEADHDVAGDLARLMSPFAERYGVIDTP
MAB_3596c|M.abscessus_ATCC_199      QEDASILARSIVRLAISYVSMPPESDHDVALDMARLLSPFVETNALADKA
MLBr_00064|M.leprae_Br4923          TLPATELATALNLMNERALFASFTAEQPHVPESRVLDTLVHIWVSSIYNE
                                       *  *: ::  :    :  .  :::  . :   * : .    .     

MMAR_1294|M.marinum_M               ------------
MUL_2593|M.ulcerans_Agy99           ------------
Mb3277c|M.bovis_AF2122/97           ------------
Rv3249c|M.tuberculosis_H37Rv        ------------
MAV_4212|M.avium_104                ------------
Mflv_4718|M.gilvum_PYR-GCK          VEGGNSQVTRRP
Mvan_1745|M.vanbaalenii_PYR-1       ------------
TH_0467|M.thermoresistible__bu      ------------
MSMEG_1842|M.smegmatis_MC2_155      ------------
MAB_3596c|M.abscessus_ATCC_199      ------------
MLBr_00064|M.leprae_Br4923          IR----------