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MRATHRAEPCRHARSRNTASQGTAVTASAGPGTITVARVGLSNDKRVSYAEASRVLLRDSILDGMREMLL TRDWSAITLSDVAKAAGISRQTIYNEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRD FFVESAADPLVISLLTGTSKPDLLQLITTDSAPIINHCSSRLTESFMSSWVRVSQEDAGVLARAIVRLAM SYISMPPEADHDVARDLARLMTPFAERYGVIDP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1745 | - | - | 100% (243) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0372 | - | 2e-08 | 25.84% (178) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3496 | - | 7e-08 | 27.33% (150) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3277c | - | 2e-84 | 75.76% (198) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4718 | - | 1e-106 | 81.40% (242) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3249c | - | 2e-84 | 75.76% (198) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3596c | - | 2e-71 | 63.96% (197) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1294 | - | 5e-86 | 77.78% (198) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4212 | - | 1e-80 | 73.23% (198) | putative transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_1842 | - | 3e-89 | 79.33% (208) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0467 | - | 1e-92 | 84.92% (199) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2593 | - | 1e-85 | 77.27% (198) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3277c|M.bovis_AF2122/97 -----------------------------------MSTPSAT----VAPV
Rv3249c|M.tuberculosis_H37Rv -----------------------------------MSTPSAT----VAPV
MMAR_1294|M.marinum_M ----------------------------------MIDTNSFAKRDIVGPV
MUL_2593|M.ulcerans_Agy99 ---------------MPRLRCGKGGLRDGGGGSTVIDTNSFAKRDIVGPV
MAV_4212|M.avium_104 -------------------------------------------------M
Mvan_1745|M.vanbaalenii_PYR-1 -MRATHRAEPC----RHARSRNTASQGTAVTASAGPGTITVARVGL-SND
Mflv_4718|M.gilvum_PYR-GCK -MTAQPIATSARVATRHADQRRADTRARGASLGPVRATVIVAPVGG-GND
TH_0467|M.thermoresistible__bu ---------------------------------------VVSRR-----D
MSMEG_1842|M.smegmatis_MC2_155 MIHAVTHAVAG---------AQFGAPARVVRGPLTAESDIVARVSRPRAK
MAB_3596c|M.abscessus_ATCC_199 -MTDVLP--------------GRDALTSASVPARLPGVTRPDALRAGGSS
Mb3277c|M.bovis_AF2122/97 KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
Rv3249c|M.tuberculosis_H37Rv KRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIY
MMAR_1294|M.marinum_M KRVPYAEASRVLLRDSVLDAMRDLLLTRDWSAITLSDVARSAGISRQTIY
MUL_2593|M.ulcerans_Agy99 KRVPYAEASRVLLRDSVLDAMRDLLFTRDWSAITLSDVARSAGISRQTIY
MAV_4212|M.avium_104 KRMPYAEASRALLRDSVLDAMRDLLVTRDWSAITLSDVARAAGISRQTIY
Mvan_1745|M.vanbaalenii_PYR-1 KRVSYAEASRVLLRDSILDGMREMLLTRDWSAITLSDVAKAAGISRQTIY
Mflv_4718|M.gilvum_PYR-GCK KRISYAEASRVLLRDSILDGMREMLLARDWSQITLSDVAKAAGISRQTIY
TH_0467|M.thermoresistible__bu KRVPYAEASRVLLRDSILDGMRELLQTRDWSQITLADVAKAAGISRQTIY
MSMEG_1842|M.smegmatis_MC2_155 QRMPYAEASRVLLRDSILDGMRDLLLTRDWSAITLSHVAQAAGVSRQTIY
MAB_3596c|M.abscessus_ATCC_199 HRVPYAEAARALLRESVLDALGDLLRQRDWSAVTMSDVSRRAGVSRQTLY
:*:.****:*.***:*:**.: ::* **** :*::.*:: **:****:*
Mb3277c|M.bovis_AF2122/97 NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
Rv3249c|M.tuberculosis_H37Rv NEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAE
MMAR_1294|M.marinum_M NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MUL_2593|M.ulcerans_Agy99 NEFGSRQGLAQGYALRLADRLVDKVHAALDANVGNIYEAFLQGFRSFFGE
MAV_4212|M.avium_104 NEFGSRQGLAQGYALRLADRLVDTIHEALDAHVGNIYESFLDAFRRFFAD
Mvan_1745|M.vanbaalenii_PYR-1 NEFGSRQGLAQGYAMRLADRLVDQIHGAINGNAGDVYAAFLQGFRDFFVE
Mflv_4718|M.gilvum_PYR-GCK NEFGSRQGLAQGYAMRLADRLVDQIHAAIDNNVGDMYAAFLQGFRDFFVE
TH_0467|M.thermoresistible__bu NEFGSRQGLAQGYALRLADRLVDEVDEAIANNVGDIHAAFLAGFRKFFAE
MSMEG_1842|M.smegmatis_MC2_155 NEFGSRQGLAEGYAMRLADRLVDAVDDAINNNVGDVYAAFLEGFRAFFAE
MAB_3596c|M.abscessus_ATCC_199 NEFGSRQGLAQGYALRLAHRLVDAVGDAIYAHVGDIHGALHSGFADFFAE
**********:***:***.**** : :: :.*:.: :: .* ** :
Mb3277c|M.bovis_AF2122/97 SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
Rv3249c|M.tuberculosis_H37Rv SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATT
MMAR_1294|M.marinum_M SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MUL_2593|M.ulcerans_Agy99 SAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLATAFTQTWVATS
MAV_4212|M.avium_104 AAADPLVTSLRTGVAKPDLLQLITTDSAVIITRASARLASALTHTWVSTT
Mvan_1745|M.vanbaalenii_PYR-1 SAADPLVISLLTGTSKPDLLQLITTDSAPIINHCSSRLTESFMSSWVRVS
Mflv_4718|M.gilvum_PYR-GCK SAADPLVISLLTGSSKPDLLQLITTDSAPIINHCSSRLTESLMGSWVRCS
TH_0467|M.thermoresistible__bu SAADPLVISLLTGSAKPDLLQLITTDSAPIITRASQRLTESFQSSWVRAS
MSMEG_1842|M.smegmatis_MC2_155 SAADPLVISLLTGAAKPDLLQIITIGSGPIITRCSERLTATFQSSWIKAS
MAB_3596c|M.abscessus_ATCC_199 SAADPMVISLLTGEAKPELMRIVTVDSALIVVPASARLTESFMNSWVAAS
:****:* ** ** :**:*::::* .*. *: .* **: :: :*: :
Mb3277c|M.bovis_AF2122/97 DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Rv3249c|M.tuberculosis_H37Rv DNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
MMAR_1294|M.marinum_M DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MUL_2593|M.ulcerans_Agy99 DDDANVLARAIVRLSLSYVSMPPEADHNVAADLARLMTPFAERHGVINVP
MAV_4212|M.avium_104 DEDAGVLARAIVRLALSYVSMPPEADHDVAADLARLMTPFAERHGVVNVG
Mvan_1745|M.vanbaalenii_PYR-1 QEDAGVLARAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVIDP-
Mflv_4718|M.gilvum_PYR-GCK EEDAGVLSRAIVRLAMSYISMPPEADHDVARDLARLMTPFAERYGVVADP
TH_0467|M.thermoresistible__bu EEDAGVLARAIVRLAMSYVSMPPEADHDVAHDLARLMTPFAERYGVIEEV
MSMEG_1842|M.smegmatis_MC2_155 DDDAGVLARAIVRLAMSYVSMPPEADHDVAGDLARLMSPFAERYGVIDTP
MAB_3596c|M.abscessus_ATCC_199 QEDASILARSIVRLAISYVSMPPESDHDVALDMARLLSPFVETNALADKA
::**.:*:*:****.:**:*****:**:** *:***::**.* .:
Mb3277c|M.bovis_AF2122/97 ------------
Rv3249c|M.tuberculosis_H37Rv ------------
MMAR_1294|M.marinum_M ------------
MUL_2593|M.ulcerans_Agy99 ------------
MAV_4212|M.avium_104 ------------
Mvan_1745|M.vanbaalenii_PYR-1 ------------
Mflv_4718|M.gilvum_PYR-GCK VEGGNSQVTRRP
TH_0467|M.thermoresistible__bu ------------
MSMEG_1842|M.smegmatis_MC2_155 ------------
MAB_3596c|M.abscessus_ATCC_199 ------------