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M. ulcerans Agy99 MUL_2972 (-)

annotation: oxidoreductase
coordinates: 3295547 - 3296491
length: 314

VPEFRFSFNVFRIDPVHTFIETCRRAEQWGYDAVFAADHLGIAAPFMTLVAAAAATDRMRVGILLLNAPW
WNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTTRTARLRQTIEELASRFAEDGFAQQ
AELREAHNIAVLRPTQRRGFGGYGPPLLVGGTGDQVLRLAAQYADTVSIACLYQVKGRPPGTMRLAIVAE
IEQRVAYVRRCAGAARHPELHTLIQEVVLTDDRREVAGMLAAKYGNLLTANEILQSPTLLIGTVEQIARQ
LRANRERYGFTHYTIPQPHVAAFAPVITVLGDLN
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_2972--100% (314)oxidoreductase
M. ulcerans Agy99MUL_3024-6e-2029.29% (280) oxidoreductase
M. ulcerans Agy99MUL_3839-2e-1430.34% (178) coenzyme F420-dependent oxidoreductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2917-3e-3537.59% (274) oxidoreductase
M. gilvum PYR-GCKMflv_1815-2e-3430.87% (311) luciferase family protein
M. tuberculosis H37RvRv2893-3e-3537.59% (274) oxidoreductase
M. leprae Br4923MLBr_00131-3e-0624.26% (169) putative oxidoreductase
M. abscessus ATCC 19977MAB_2431c-2e-2128.32% (339) luciferase-like oxidoreductase
M. marinum MMMAR_2775-1e-17998.41% (314) oxidoreductase
M. avium 104MAV_1042-1e-3431.72% (309) hypothetical protein MAV_1042
M. smegmatis MC2 155MSMEG_5592-9e-3933.77% (308) hypothetical protein MSMEG_5592
M. thermoresistible (build 8)TH_1174-9e-1829.14% (302) POSSIBLE OXIDOREDUCTASE
M. vanbaalenii PYR-1Mvan_0757-7e-3838.30% (282) luciferase family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2917|M.bovis_AF2122/97            ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
Rv2893|M.tuberculosis_H37Rv         ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
Mvan_0757|M.vanbaalenii_PYR-1       ------------------------MRFGLTTALPRDGAAAREFAQRVEAA
MUL_2972|M.ulcerans_Agy99           ---------------------MPEFRFSFNVFRIDPVHTFIETCRRAEQW
MMAR_2775|M.marinum_M               MTLRLPRTRWLARLPAGSVTPVPEFRFSFNVFRIDPVHTFIETCRRAEQW
Mflv_1815|M.gilvum_PYR-GCK          -----MPLPPAVQTWTYDHDVAKEFRFGVGVTRVSTRAKLEDDARRAEAL
MAV_1042|M.avium_104                --------------------MAKDFRFGMSMRFYKSREALLDKAKRAEDA
MSMEG_5592|M.smegmatis_MC2_155      -------------------MMPKEFRFGVSVRNAESQAQVAATARRAEDL
MAB_2431c|M.abscessus_ATCC_199      ---------------MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEAS
TH_1174|M.thermoresistible__bu      ---------------VSIRLGLQIPNFSYGTGVADLFPTVIAQAREADEA
MLBr_00131|M.leprae_Br4923          ---MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNAL
                                                               .                   :  

Mb2917|M.bovis_AF2122/97            GFDVLAFPDHLVP----------SVSPFAGATAAAMATQR--LHTGTLVL
Rv2893|M.tuberculosis_H37Rv         GFDVLAFPDHLVP----------SVSPFAGATAAAMATQR--LHTGTLVL
Mvan_0757|M.vanbaalenii_PYR-1       GIDVLTFADHLAP----------AVAPFSGATAAAAVTSR--LHVGTLVL
MUL_2972|M.ulcerans_Agy99           GYDAVFAADHLG-----------IAAPFMTLVAAAAATDR--MRVGILLL
MMAR_2775|M.marinum_M               GYDAVFAADHLG-----------IAAPFMTLVAAAAATDR--MRVGTLVL
Mflv_1815|M.gilvum_PYR-GCK          GFDVLHVPDHLG-----------GSAPFPVMTAVAMATTS--LRVGTFVL
MAV_1042|M.avium_104                GFDILCVPDHLG-----------AAAPFPTLTAVAMVTTT--LRLSMYVL
MSMEG_5592|M.smegmatis_MC2_155      GYNVIVVPDHLG-----------APAPFPTLTAIAAATDT--IRVGTCVL
MAB_2431c|M.abscessus_ATCC_199      GFDTVFVMDHFYQLPMIGTPDQPMLEAYTALGALASATST--IQLSTLVT
TH_1174|M.thermoresistible__bu      GYDAVFVMDHFYQLPMLGDPDEPMLEAYTALGGLATSTER--VQLGTLVT
MLBr_00131|M.leprae_Br4923          VPRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVT
                                        :   .::               .:      *  .    :: .  : 

Mb2917|M.bovis_AF2122/97            NNDFRHPVDTAREAAGVATLAEGRFELGLGAGHRRSEYDAAGITFDSGAT
Rv2893|M.tuberculosis_H37Rv         NNDFRHPVDTAREAAGVATLAEGRFELGLGAGHRRSEYDAAGITFDSGAT
Mvan_0757|M.vanbaalenii_PYR-1       NNDFRHPVETAREAAGVATVSDGRFELGIGAGHMKSEYDSAGIPFDGGGT
MUL_2972|M.ulcerans_Agy99           NAPWWNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTT
MMAR_2775|M.marinum_M               NAPWWNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTT
Mflv_1815|M.gilvum_PYR-GCK          NSAFYRPALLARDVAALNDLSDGRVELGLGTGYVREEFDAAGIPYPTAGE
MAV_1042|M.avium_104                NSAFYKPALLSRDMQALDLLSDGRLEIGLGTGYVREEFEAAEIPYPSARE
MSMEG_5592|M.smegmatis_MC2_155      NACFYKPALLARDVTALRDLSDGRFEVGLGAGYVREEFEAAELPFPSARE
MAB_2431c|M.abscessus_ATCC_199      GNTYRNPALLAKAVTTLDVVSGGRAILGIGAGWFELEHQQLGFEFGTFTD
TH_1174|M.thermoresistible__bu      GNTYRNPTLLAKAVTTLDVMSQGRAVLGIGTGWFELEHQQLGYEFGTFTD
MLBr_00131|M.leprae_Br4923          DAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGE-REGNEPYGVEWTKPVA
                                    .    .*.  ::       :: *:  :*:*.*  .   :     :     

Mb2917|M.bovis_AF2122/97            RVARLIESAHLIRALLDAEPVDFDGQHYRVHAEAG----SLVAPPKVRVP
Rv2893|M.tuberculosis_H37Rv         RVARLIESAHLIRALLDAEPVDFDGQHYRVHAEAG----SLVAPPKVRVP
Mvan_0757|M.vanbaalenii_PYR-1       RVSRLVESVTVLRALLHGDAVDFDGDHYRVHAAAG----EIVAAPVHRVP
MUL_2972|M.ulcerans_Agy99           RTARLRQTIEELASRFAEDGFAQQAELREAHNIAVLRPTQRRGFGGYGPP
MMAR_2775|M.marinum_M               RTARLRQTIEELASRFAEEGFAQQAELREAHNIAVLRPTQRRGFGGYGPP
Mflv_1815|M.gilvum_PYR-GCK          RVDHLKLTAAHIAEHLPDV------------------------------P
MAV_1042|M.avium_104                RVDYLEHMTKYLKEHHPST------------------------------P
MSMEG_5592|M.smegmatis_MC2_155      RIDHLRHTTEYLREHVSDV------------------------------P
MAB_2431c|M.abscessus_ATCC_199      RFERLTEALEIIPPMLRGERPTFEGKYYRTESALN------EPRLRPNIP
TH_1174|M.thermoresistible__bu      RFNRLYEALEIIVPMIEGKRPTFEGRYYRVESAAA------EPRFRDRIP
MLBr_00131|M.leprae_Br4923          RFQEALATIRALWDSNGELVSRESQFFPLHNALFD-----LPPYRGKWPE
                                    *          :                                      

Mb2917|M.bovis_AF2122/97            LLVGGNGTE-VLRLGGRIAD------IVGLAGISHNRDATQVRFTHFDAD
Rv2893|M.tuberculosis_H37Rv         LLVGGNGTE-VLRLGGRIAD------IVGLAGISHNRDATQVRFTHFDAD
Mvan_0757|M.vanbaalenii_PYR-1       ILIGGNGTR-VLQLAGRIAD------IVGFAGISHNRDATRVRLSHFDGA
MUL_2972|M.ulcerans_Agy99           LLVGGTGDQ-VLRLAAQYAD------TVSIACLYQVKGRPPGTMRLAIVA
MMAR_2775|M.marinum_M               LLVGGTGDQ-VLRLAAQYAD------TVSIACLYQVKGRPPGTMRLATVA
Mflv_1815|M.gilvum_PYR-GCK          IMIAGNGDR-VLRTAARFAD------IVGFTGGDRAATGDE--------D
MAV_1042|M.avium_104                LIIAGNGDR-VLTIAARNAD------IIGLTG--AKVRDVE--------D
MSMEG_5592|M.smegmatis_MC2_155      IMVAGNGDR-LLTVAAQTAD------IVGLTGGDGVPDGDH--------D
MAB_2431c|M.abscessus_ATCC_199      IMIGGSGEKKTFGLAVKYAD------HLNLLSS---------------LD
TH_1174|M.thermoresistible__bu      LMIGGSGEKKTIPLAARRFD------HLNLIAG---------------FD
MLBr_00131|M.leprae_Br4923          IWVAAHGPR-MLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRD
                                    : :.. * .  :    :  *       :                      

Mb2917|M.bovis_AF2122/97            GLADRIAVVR--------HAAGDRFEAIELNALIQAVVCTNDRNA-AAAE
Rv2893|M.tuberculosis_H37Rv         GLADRIAVVR--------HAAGDRFEAIELNALIQAVVCTNDRNA-AAAE
Mvan_0757|M.vanbaalenii_PYR-1       GLADRIGVVR--------EAAGERFAQIELNALIQAVVVTTDRQR-AAAE
MUL_2972|M.ulcerans_Agy99           EIEQRVAYVR--------RCAGAARHPELHTLIQEVVLTDDRREV-AGML
MMAR_2775|M.marinum_M               EIEQRVAYVR--------RCAGAARHPELHTLIQEVVLTDDRRKV-AGML
Mflv_1815|M.gilvum_PYR-GCK          PLGDRIGFVR--------AAAGERFAALELNIAITAIPLDSSGQP-DLTI
MAV_1042|M.avium_104                PFAERVEFVR--------NAAGDRFDSLELNLAITAMPRVGETEP-DLKL
MSMEG_5592|M.smegmatis_MC2_155      PLAERISFLR--------KAADGR--DLELNITFTAIPAAGSEMP-DLRL
MAB_2431c|M.abscessus_ATCC_199      EIPHKLTVLRQRC-----EEAGRDPSTLETSAFFSVFIDDDSATAWKLAA
TH_1174|M.thermoresistible__bu      ELPGKVAAVKRSC-----EEIGRDPDTLETSTLVSVMVDDN---------
MLBr_00131|M.leprae_Br4923          PMSITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHP
                                     :      ::           .              .             

Mb2917|M.bovis_AF2122/97            LAATLGGITPEQ------------VLESPF------LLLGTHEQMAEALA
Rv2893|M.tuberculosis_H37Rv         LAATLGGITPEQ------------VLESPF------LLLGTHEQMAEALA
Mvan_0757|M.vanbaalenii_PYR-1       LAAAFG-ADPET------------LLCSPF------VLLGTHEQMAEQLL
MUL_2972|M.ulcerans_Agy99           AAKYGNLLTANE------------ILQSPT------LLIGTVEQIARQLR
MMAR_2775|M.marinum_M               AAKYGNLLTANE------------ILQSPT------LLIGTVEQIARQLR
Mflv_1815|M.gilvum_PYR-GCK          PRISLPGLSDDE------------LLRHPS------VLSGSTTEIADRIH
MAV_1042|M.avium_104                TRSYSPELTDEQ------------ILSMPS------VLSGSPRDIADTLS
MSMEG_5592|M.smegmatis_MC2_155      TRRFLGHLTDEQ------------LLRHPG------VLAGSASDMADRLR
MAB_2431c|M.abscessus_ATCC_199      SQLSQNGIDLDT------------LPDEARAQVLGRTLVGNPEEIAEQVQ
TH_1174|M.thermoresistible__bu      -------ITDDM------------LPEKAR----GRLLVGSAERIAEQLQ
MLBr_00131|M.leprae_Br4923          MGADFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVA
                                                                .        : *.   :   : 

Mb2917|M.bovis_AF2122/97            ARQRRFGVSYWTVFDEWAGRASAMRDIAEVIALLRYG------
Rv2893|M.tuberculosis_H37Rv         ARQRRFGVSYWTVFDEWAGRASAMRDIAEVIALLRYG------
Mvan_0757|M.vanbaalenii_PYR-1       ARRREFGIGYWTVFDELPGRESALPDISEVIALLR--------
MUL_2972|M.ulcerans_Agy99           ANRERYGFTHYTIPQPH------VAAFAPVITVLGDLN-----
MMAR_2775|M.marinum_M               ANRERYGFTHYTIPQPH------VAAFAPVITVLGDLN-----
Mflv_1815|M.gilvum_PYR-GCK          GYRDVYGISYVIVQMRH------AEAFGAVIDLLR--------
MAV_1042|M.avium_104                AYRDKYGVSSFTVQDNH------IDNFAKVIAELR--------
MSMEG_5592|M.smegmatis_MC2_155      QLRDTYGVSYFIVQIPH------IETFAKVIAELR--------
MAB_2431c|M.abscessus_ATCC_199      TRVLDQGIDSVTLNAP--ATGHLPGVVELIGNTLRPLFKN---
TH_1174|M.thermoresistible__bu      TKVLDAGVDGVIVNMATKVQGYRPGLITALGEALRPRVGA---
MLBr_00131|M.leprae_Br4923          EWR-DHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL
                                          *.    :             .  :