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TLRLPRTRWLARLPAGSVTPVPEFRFSFNVFRIDPVHTFIETCRRAEQWGYDAVFAADHLGIAAPFMTLV AAAAATDRMRVGTLVLNAPWWNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTTRTAR LRQTIEELASRFAEEGFAQQAELREAHNIAVLRPTQRRGFGGYGPPLLVGGTGDQVLRLAAQYADTVSIA CLYQVKGRPPGTMRLATVAEIEQRVAYVRRCAGAARHPELHTLIQEVVLTDDRRKVAGMLAAKYGNLLTA NEILQSPTLLIGTVEQIARQLRANRERYGFTHYTIPQPHVAAFAPVITVLGDLN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2775 | - | - | 100% (335) | oxidoreductase |
| M. marinum M | MMAR_4587 | - | 4e-35 | 33.33% (309) | oxidoreductase |
| M. marinum M | MMAR_2729 | - | 4e-22 | 29.82% (275) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2917 | - | 1e-36 | 35.71% (308) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1815 | - | 4e-36 | 31.83% (311) | luciferase family protein |
| M. tuberculosis H37Rv | Rv2893 | - | 1e-36 | 35.71% (308) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 3e-06 | 30.97% (113) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_2431c | - | 3e-23 | 29.20% (339) | luciferase-like oxidoreductase |
| M. avium 104 | MAV_1042 | - | 1e-34 | 32.49% (317) | hypothetical protein MAV_1042 |
| M. smegmatis MC2 155 | MSMEG_5592 | - | 8e-40 | 34.42% (308) | hypothetical protein MSMEG_5592 |
| M. thermoresistible (build 8) | TH_1174 | - | 2e-19 | 30.13% (302) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_2972 | - | 1e-179 | 98.41% (314) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0757 | - | 9e-39 | 37.86% (280) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2775|M.marinum_M MTLRLPRTRWLARLPAGSVTPVPEFRFSFNVFRIDPVHTFIETCRRAEQW
MUL_2972|M.ulcerans_Agy99 ---------------------MPEFRFSFNVFRIDPVHTFIETCRRAEQW
MAV_1042|M.avium_104 --------------------MAKDFRFGMSMRFYKSREALLDKAKRAEDA
MSMEG_5592|M.smegmatis_MC2_155 -------------------MMPKEFRFGVSVRNAESQAQVAATARRAEDL
Mflv_1815|M.gilvum_PYR-GCK -----MPLPPAVQTWTYDHDVAKEFRFGVGVTRVSTRAKLEDDARRAEAL
Mb2917|M.bovis_AF2122/97 ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
Rv2893|M.tuberculosis_H37Rv ------------MTVASTAHHTRRLRFGLAAPLPRAGTQMRAFAQAVEAA
Mvan_0757|M.vanbaalenii_PYR-1 ------------------------MRFGLTTALPRDGAAAREFAQRVEAA
MAB_2431c|M.abscessus_ATCC_199 ---------------MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEAS
TH_1174|M.thermoresistible__bu ---------------VSIRLGLQIPNFSYGTGVADLFPTVIAQAREADEA
MLBr_00348|M.leprae_Br4923 ---------------MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGA
: .:
MMAR_2775|M.marinum_M GYDAVFAADHLG-----------IAAPFMTLVAAAAATDRMRVGTLVLNA
MUL_2972|M.ulcerans_Agy99 GYDAVFAADHLG-----------IAAPFMTLVAAAAATDRMRVGILLLNA
MAV_1042|M.avium_104 GFDILCVPDHLG-----------AAAPFPTLTAVAMVTTTLRLSMYVLNS
MSMEG_5592|M.smegmatis_MC2_155 GYNVIVVPDHLG-----------APAPFPTLTAIAAATDTIRVGTCVLNA
Mflv_1815|M.gilvum_PYR-GCK GFDVLHVPDHLG-----------GSAPFPVMTAVAMATTSLRVGTFVLNS
Mb2917|M.bovis_AF2122/97 GFDVLAFPDHLVP----------SVSPFAGATAAAMATQRLHTGTLVLNN
Rv2893|M.tuberculosis_H37Rv GFDVLAFPDHLVP----------SVSPFAGATAAAMATQRLHTGTLVLNN
Mvan_0757|M.vanbaalenii_PYR-1 GIDVLTFADHLAP----------AVAPFSGATAAAAVTSRLHVGTLVLNN
MAB_2431c|M.abscessus_ATCC_199 GFDTVFVMDHFYQLPMIGTPDQPMLEAYTALGALASATSTIQLSTLVTGN
TH_1174|M.thermoresistible__bu GYDAVFVMDHFYQLPMLGDPDEPMLEAYTALGGLATSTERVQLGTLVTGN
MLBr_00348|M.leprae_Br4923 GFDAVFTGEAWG------------SDAYTPLAWWGSSTQRVRLGTSVVQL
* : : : .: . * :: . :
MMAR_2775|M.marinum_M PWWNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTTR-
MUL_2972|M.ulcerans_Agy99 PWWNPALLARDIATTDVLTGGRLEVGLGAGHMKWEYDQADIPFPSFTTR-
MAV_1042|M.avium_104 AFYKPALLSRDMQALDLLSDGRLEIGLGTGYVREEFEAAEIPYPSARER-
MSMEG_5592|M.smegmatis_MC2_155 CFYKPALLARDVTALRDLSDGRFEVGLGAGYVREEFEAAELPFPSARER-
Mflv_1815|M.gilvum_PYR-GCK AFYRPALLARDVAALNDLSDGRVELGLGTGYVREEFDAAGIPYPTAGER-
Mb2917|M.bovis_AF2122/97 DFRHPVDTAREAAGVATLAEGRFELGLGAGHRRSEYDAAGITFDSGATR-
Rv2893|M.tuberculosis_H37Rv DFRHPVDTAREAAGVATLAEGRFELGLGAGHRRSEYDAAGITFDSGATR-
Mvan_0757|M.vanbaalenii_PYR-1 DFRHPVETAREAAGVATVSDGRFELGIGAGHMKSEYDSAGIPFDGGGTR-
MAB_2431c|M.abscessus_ATCC_199 TYRNPALLAKAVTTLDVVSGGRAILGIGAGWFELEHQQLGFEFGTFTDR-
TH_1174|M.thermoresistible__bu TYRNPTLLAKAVTTLDVMSQGRAVLGIGTGWFELEHQQLGYEFGTFTDR-
MLBr_00348|M.leprae_Br4923 SARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKPLSRT
*. : :: ** :*:*.. . : *
MMAR_2775|M.marinum_M ---TARLRQTIEELASRFAEEGFAQQAELREAHNIAVLRPTQRRGFGGYG
MUL_2972|M.ulcerans_Agy99 ---TARLRQTIEELASRFAEDGFAQQAELREAHNIAVLRPTQRRGFGGYG
MAV_1042|M.avium_104 ---VDYLEHMTKYLKEHHP------------------------------S
MSMEG_5592|M.smegmatis_MC2_155 ---IDHLRHTTEYLREHVS------------------------------D
Mflv_1815|M.gilvum_PYR-GCK ---VDHLKLTAAHIAEHLP------------------------------D
Mb2917|M.bovis_AF2122/97 ---VARLIESAHLIRALLDAE----PVDFDGQHYRVHAEAGSLVAPPKVR
Rv2893|M.tuberculosis_H37Rv ---VARLIESAHLIRALLDAE----PVDFDGQHYRVHAEAGSLVAPPKVR
Mvan_0757|M.vanbaalenii_PYR-1 ---VSRLVESVTVLRALLHGD----AVDFDGDHYRVHAAAGEIVAAPVHR
MAB_2431c|M.abscessus_ATCC_199 ---FERLTEALEIIPPMLRGE------RPTFEGKYYRTESALNEPRLRPN
TH_1174|M.thermoresistible__bu ---FNRLYEALEIIVPMIEGK------RPTFEGRYYRVESAAAEPRFRDR
MLBr_00348|M.leprae_Br4923 REYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHPLRAD
:
MMAR_2775|M.marinum_M PPLLVGGTGDQ-VLRLAAQYAD--------------TVSIACLYQVKGRP
MUL_2972|M.ulcerans_Agy99 PPLLVGGTGDQ-VLRLAAQYAD--------------TVSIACLYQVKGRP
MAV_1042|M.avium_104 TPLIIAGNGDR-VLTIAARNAD--------------IIGLTG-AKVRD--
MSMEG_5592|M.smegmatis_MC2_155 VPIMVAGNGDR-LLTVAAQTAD--------------IVGLTGGDGVPDG-
Mflv_1815|M.gilvum_PYR-GCK VPIMIAGNGDR-VLRTAARFAD--------------IVGFTGGDRAATG-
Mb2917|M.bovis_AF2122/97 VPLLVGGNGTE-VLRLGGRIAD--------------IVGLAGISHNRDAT
Rv2893|M.tuberculosis_H37Rv VPLLVGGNGTE-VLRLGGRIAD--------------IVGLAGISHNRDAT
Mvan_0757|M.vanbaalenii_PYR-1 VPILIGGNGTR-VLQLAGRIAD--------------IVGFAGISHNRDAT
MAB_2431c|M.abscessus_ATCC_199 IPIMIGGSGEKKTFGLAVKYAD--------------HLNLLSSLDEIPH-
TH_1174|M.thermoresistible__bu IPLMIGGSGEKKTIPLAARRFD--------------HLNLIAGFDELPG-
MLBr_00348|M.leprae_Br4923 IPIMLGAEGPK-NVALAAEICDGWLPIFFSPRMADMYNEWLDEGFARTGA
*:::.. * . . . . *
MMAR_2775|M.marinum_M PGTMRLATVAEIEQRVAYVRRCAGAARHPELHTLIQEVVLTDDRRKVAGM
MUL_2972|M.ulcerans_Agy99 PGTMRLAIVAEIEQRVAYVRRCAGAARHPELHTLIQEVVLTDDRREVAGM
MAV_1042|M.avium_104 -------VEDPFAERVEFVRNAAGDRFDSLELNLAITAMPRVGETEPDLK
MSMEG_5592|M.smegmatis_MC2_155 -------DHDPLAERISFLRKAADGR--DLELNITFTAIPAAGSEMPDLR
Mflv_1815|M.gilvum_PYR-GCK -------DEDPLGDRIGFVRAAAGERFAALELNIAITAIPLDSSGQPDLT
Mb2917|M.bovis_AF2122/97 QVRFTHFDADGLADRIAVVRHAAGDRFEAIELNALIQAVVCTNDRNAAAA
Rv2893|M.tuberculosis_H37Rv QVRFTHFDADGLADRIAVVRHAAGDRFEAIELNALIQAVVCTNDRNAAAA
Mvan_0757|M.vanbaalenii_PYR-1 RVRLSHFDGAGLADRIGVVREAAGERFAQIELNALIQAVVVTTDRQRAAA
MAB_2431c|M.abscessus_ATCC_199 -------KLTVLRQRCEEAGRDPSTLETSAFFSVFIDDDSATAWKLAASQ
TH_1174|M.thermoresistible__bu -------KVAAVKRSCEEIGRDPDTLETSTLVSVMVDDN-----------
MLBr_00348|M.leprae_Br4923 RRSREDFEICASAQIVVTEDRAAAFAGIKPFLALYMGGMGAEGTNFHADV
.
MMAR_2775|M.marinum_M LAAKYGNLLTANEILQSP---TLLIGTVEQIARQLRANRERYGFTHYTIP
MUL_2972|M.ulcerans_Agy99 LAAKYGNLLTANEILQSP---TLLIGTVEQIARQLRANRERYGFTHYTIP
MAV_1042|M.avium_104 LTRSYSPELTDEQILSMP---SVLSGSPRDIADTLSAYRDKYGVSSFTVQ
MSMEG_5592|M.smegmatis_MC2_155 LTRRFLGHLTDEQLLRHP---GVLAGSASDMADRLRQLRDTYGVSYFIVQ
Mflv_1815|M.gilvum_PYR-GCK IPRISLPGLSDDELLRHP---SVLSGSTTEIADRIHGYRDVYGISYVIVQ
Mb2917|M.bovis_AF2122/97 ELAATLGGITPEQVLESP---FLLLGTHEQMAEALAARQRRFGVSYWTVF
Rv2893|M.tuberculosis_H37Rv ELAATLGGITPEQVLESP---FLLLGTHEQMAEALAARQRRFGVSYWTVF
Mvan_0757|M.vanbaalenii_PYR-1 ELAAAFG-ADPETLLCSP---FVLLGTHEQMAEQLLARRREFGIGYWTVF
MAB_2431c|M.abscessus_ATCC_199 LSQNGIDLDTLPDEARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSVTLN
TH_1174|M.thermoresistible__bu -----ITDDMLPEKAR----GRLLVGSAERIAEQLQTKVLDAGVDGVIVN
MLBr_00348|M.leprae_Br4923 YRRMGYAEVVDEVTALFR--SNQKDKAAEIIPNELVDSTMIVGDVDYVCK
:. : *
MMAR_2775|M.marinum_M QPH------VAAFAPVITVLGDLN------
MUL_2972|M.ulcerans_Agy99 QPH------VAAFAPVITVLGDLN------
MAV_1042|M.avium_104 DNH------IDNFAKVIAELR---------
MSMEG_5592|M.smegmatis_MC2_155 IPH------IETFAKVIAELR---------
Mflv_1815|M.gilvum_PYR-GCK MRH------AEAFGAVIDLLR---------
Mb2917|M.bovis_AF2122/97 DEWAGRASAMRDIAEVIALLRYG-------
Rv2893|M.tuberculosis_H37Rv DEWAGRASAMRDIAEVIALLRYG-------
Mvan_0757|M.vanbaalenii_PYR-1 DELPGRESALPDISEVIALLR---------
MAB_2431c|M.abscessus_ATCC_199 AP--ATGHLPGVVELIGNTLRPLFKN----
TH_1174|M.thermoresistible__bu MATKVQGYRPGLITALGEALRPRVGA----
MLBr_00348|M.leprae_Br4923 QIAAWSAAGVTMMMVSASSVEQVRDLAGLF
. :