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AAPQRARLRSSKERVRDYALFVVLVGPNVALLLLFVYRPLADNIRLSFFDWNVSDPSARFVGLSNYTEWF TRSDTRQIVFNTAVFTGAAVVGSMVLGLALAMLLDRPLRGRNLVRSTVFAPFVISGAAVGLAAQFVFDPH FGLIQDLLRRIGVGVPDFYQDARWALFMVTITYVWKNLGYTFVIYLAALQGVRRDLLEAAEIDGASRWAV FRRVLLPQLRPTTFFLSITVLINSLQVFDVINVMTRGGPEGTGTTTMVYQVYVETFRNFRAGYGATVATI MFLVLLAVTYYQVRVMDRGQRQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2835c | ugpA | - | 100% (303) | PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPA |
| M. tuberculosis H37Rv | Rv2040c | - | 2e-41 | 33.69% (279) | sugar-transport integral membrane protein ABC transporter |
| M. tuberculosis H37Rv | Rv2316 | uspA | 7e-39 | 33.81% (278) | sugar-transport integral membrane protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2859c | ugpAb | 1e-100 | 100.00% (180) | sn-glycerol-3-phosphate ABC transporter integral membrane |
| M. gilvum PYR-GCK | Mflv_3776 | - | 3e-34 | 33.45% (278) | binding-protein-dependent transport systems inner membrane |
| M. leprae Br4923 | MLBr_01768 | uspA | 1e-37 | 31.96% (291) | sugar transport integral membrane protein |
| M. abscessus ATCC 19977 | MAB_1717c | - | 5e-36 | 31.91% (282) | sugar ABC transporter, permease protein |
| M. marinum M | MMAR_1898 | ugpA | 1e-147 | 88.50% (287) | SN-glycerol-3-phosphate transport integral membrane protein |
| M. avium 104 | MAV_2477 | - | 6e-42 | 34.41% (279) | sugar ABC transporter permease |
| M. smegmatis MC2 155 | MSMEG_0516 | - | 6e-42 | 33.82% (275) | sugar transport system |
| M. thermoresistible (build 8) | TH_2010 | - | 8e-35 | 31.39% (274) | sugar ABC transporter permease protein |
| M. ulcerans Agy99 | MUL_2126 | ugpA | 1e-147 | 88.50% (287) | SN-glycerol-3-phosphate transport integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_2623 | - | 2e-33 | 34.42% (276) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2835c|M.tuberculosis_H37Rv ----------------------------MAAPQRARLRSSKERVRDYALF
Mb2859c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1898|M.marinum_M ----------------------------MTTTRPRRNRS----WRDYALF
MUL_2126|M.ulcerans_Agy99 ----------------------------MTTTRPRRNRS----WRDYALF
MAV_2477|M.avium_104 ------------------------MTALDTEAGRRTPKNPSPWRRHAWAG
MSMEG_0516|M.smegmatis_MC2_155 ------------------------MTG--HVATRHSWRDRLGHSEHV-AG
MLBr_01768|M.leprae_Br4923 MCAHFNTSMTNTGDDTEQSDEVGSISRLRGRKTHRTRALTKNHPRSIALA
MAB_1717c|M.abscessus_ATCC_199 ----------------------------------------MSRSRQTAVA
Mflv_3776|M.gilvum_PYR-GCK ----------------------------------------------MKFQ
Mvan_2623|M.vanbaalenii_PYR-1 ------------------------------------------MMPSLRFQ
TH_2010|M.thermoresistible__bu -----------MTAIAPGASEHLTGSEADRVARIKHAKQQGVSRAEGWRR
Rv2835c|M.tuberculosis_H37Rv VVLVGPNVALLLLFVYRPLADNIRLSFFDWNVSDPSAR-FVGLSNYTEWF
Mb2859c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1898|M.marinum_M VALVGPNLALLLLFVYRPLVDNIRLSFFDWNISDPTAE-FVGFSNYIEWF
MUL_2126|M.ulcerans_Agy99 VALVGPNLALLLLFVYRPLVDNIRLSFFDWNISDPTAE-FVGFSNYIEWF
MAV_2477|M.avium_104 RLFVAPNMVAVAVFMLFPLGFSLYMSFQRWDVFTPPK--FVGLKNFTDLF
MSMEG_0516|M.smegmatis_MC2_155 WTLVSPAVVLIGVFGLLPVLMSLTLSFQHSDLLTPETP-WVGLENYRKLA
MLBr_01768|M.leprae_Br4923 YALLAPSLFGVVTFLLLPIIVVIWLSLFRWDLLGPLH--YVGLANWRSVL
MAB_1717c|M.abscessus_ATCC_199 YGLLAPSLFGVAAFLLLPILVVVWLSLCRWDLLGPIE--FVGLDNWRSVL
Mflv_3776|M.gilvum_PYR-GCK HGMVAPLVALFVGVVGFPLGYAAYLSVTDYKLTDQGAPDIVGADNFVATF
Mvan_2623|M.vanbaalenii_PYR-1 HGMVAPLAALFVGVVGFPLGYAAYLSVTDYKLTDRGAPNLVGADNYVAAF
TH_2010|M.thermoresistible__bu RGPLLPALIFMIIVTQVPFLFTLYFSTLSWNLVRPGSREFVGFQNYVDVV
Rv2835c|M.tuberculosis_H37Rv T-RSDTRQIVFNTAVFTGAAVVGSMVLGLALAMLLDRPLRGRNLVRSTVF
Mb2859c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_1898|M.marinum_M S-RPDTRQIVANTAIFTTAAVAGSMVLGLLLAMLLDQPLRGRNLVRSTVF
MUL_2126|M.ulcerans_Agy99 S-RPDTRQIVANTAIFTTAAVAGSMVLGLLLAMLLDQPLRGRNLVRSTVF
MAV_2477|M.avium_104 SSDPLFLIAIRNTVIFTLGSVVPTVAISLAVAGVLNQKVRGIGIFRTIVF
MSMEG_0516|M.smegmatis_MC2_155 D-DPVFVDAIKHTIIYTALFVPGTMIVGLLVAAALNRSVRFISVYRTAAY
MLBr_01768|M.leprae_Br4923 T-DPNFANSLIVTAVFVAIVVPTQTMLGLLIATMLARQLPGTGVFRTLYV
MAB_1717c|M.abscessus_ATCC_199 T-DGTFGHSLLVTLLFVALVIPVQTALGLAAATLLVRGLPGTVLFRTIYV
Mflv_3776|M.gilvum_PYR-GCK G-DSGFWNAFGTTALYVLVAVGLELVIGLAIALALQKQRWARDLTRSMLL
Mvan_2623|M.vanbaalenii_PYR-1 S-DGAFWGAFGTTALYVLVAVGLELVIGLAIALALQKQRWAKDLTRSMLL
TH_2010|M.thermoresistible__bu Q-DSTFWQVAVNSVLIIVVTVLVSVLLGLGLALLLDRVFLGRGIVRTLLI
Rv2835c|M.tuberculosis_H37Rv APFVISGAAVGLAAQ-FVFDPHFGLIQDLLRRIGVGVPDFYQDARWALFM
Mb2859c|M.bovis_AF2122/97 ---MISGAAVGLAAQ-FVFDPHFGLIQDLLRRIGVGVPDFYQDARWALFM
MMAR_1898|M.marinum_M APFVISGAAVGLAAQ-FVFDPHFGLVQDLLHRVGVNAPDFYQDTPWALFM
MUL_2126|M.ulcerans_Agy99 APFVISGAAVGLAAQ-FVFDPHFGLVQDLLHRVGVNAPDFYQDTPWALFM
MAV_2477|M.avium_104 LPLAISSVVMAVVWQ-FVFNTDNGLLNIMLGWVGLGPVPWLVEPRWAMAS
MSMEG_0516|M.smegmatis_MC2_155 VTMAVSTISQGIIFL-WLTDRDYGLVNAALNTVGISSQPFLASPSQALYV
MLBr_01768|M.leprae_Br4923 LPWICAPLAIAVLWR-WLLAPTDGAFSMVLRHR----IEWLSDPSLALPV
MAB_1717c|M.abscessus_ATCC_199 IPWICAPLAIGVLWH-WMLAPTDGAVNALLGQR----VEWLTDPSLALPV
Mflv_3776|M.gilvum_PYR-GCK APMFITPIAVGLTFR-FLLNDQLGAIPAMLHAIGIDYDFFG--PGRALYT
Mvan_2623|M.vanbaalenii_PYR-1 APMFITPIAVGLTFR-FLLNDQLGAIPAMLDAIGVEYDFFG--PGRALFT
TH_2010|M.thermoresistible__bu TPFLVTPVAGALMWKTAMLDPVFGIVNWLLSPFGVHQVDWV--SRFPLTS
: .: : * . * : . .:
Rv2835c|M.tuberculosis_H37Rv VTITYVWKNLGYTFVIYLAALQGVRRDLLEAAEIDGASRWAVFRRVLLPQ
Mb2859c|M.bovis_AF2122/97 VTITYVWKNLGYTFVIYLAALQGVRRDLLEAAEIDGASRWAVFRRVLLPQ
MMAR_1898|M.marinum_M VTVTYVWKNLGYTCVIYLAALQGVRRDLLEAAEIDGASRWTSFRRVLLPQ
MUL_2126|M.ulcerans_Agy99 VTVTYVWKNLGYTCVIYLAALQGVRRDLLEAAEIDGASRWTSFRRVLLPQ
MAV_2477|M.avium_104 LCIVSVWRSVPFATVVLLAAMQGVPETVYEAARIDGAGEIRQFFAITVPL
MSMEG_0516|M.smegmatis_MC2_155 IVAMTIWGWTGFSVIVYLAALQGVPAELHEAAAIDGASAFTRFRTITVPL
MLBr_01768|M.leprae_Br4923 VSAVVVWTNVGYVSLSFLAGLLSIPEDINAAARTDGADAWQRFWRITLPM
MAB_1717c|M.abscessus_ATCC_199 VAAVSVWTNVGYVALFFMAGLLAIPGDVHNAARVDGATAWQRFRRITLPM
Mflv_3776|M.gilvum_PYR-GCK LAFIDVWQWTPFMVLLLLAGLESIPKEPLDAARVDGARGLYVLRRVTLPL
Mvan_2623|M.vanbaalenii_PYR-1 LAFIDVWQWTPFMVLLLLAGLESIPKEPLDAARLDGASGLYVLRRVTLPL
TH_2010|M.thermoresistible__bu VMINLVWQWTPFMMLLILAGLQSMPRDILEAGRVDGAGTFQLFRELTLPH
: :* : : :*.: .: *. *** : : :*
Rv2835c|M.tuberculosis_H37Rv LRPTTFFLSITVLINSLQVFDVINVMTR--GGPEGTGTTTMVYQVYVETF
Mb2859c|M.bovis_AF2122/97 LRPTTFFLSITVLINSLQVFDVINVMTR--GGPEGTGTTTMVYQVYVETF
MMAR_1898|M.marinum_M LRPTTFFLSITVLINSLQVFDVINVMTR--GGPEGTGTTTMVYQVYLETF
MUL_2126|M.ulcerans_Agy99 LRPTTFFLSITVLINSLQVFDVINVMTR--GGPEGTGTTTMVYQVYLETF
MAV_2477|M.avium_104 IRGSISFVVIISIIHAFQAFDMVYVLTGPSGGPESA-TYVLGIMLFQHAF
MSMEG_0516|M.smegmatis_MC2_155 LGPANIFLVVWLTINALQLFDEVYATTR--GGPLRA-TTVIVYYLWDRAF
MLBr_01768|M.leprae_Br4923 LRPTMFFVLVTGIVSTAQVFDTVYALTD--GGPKSR-TDLVAHRIYAEAF
MAB_1717c|M.abscessus_ATCC_199 LRPTFFFVLVTGVVSAVQTFDTVYALTS--GGPQNR-TDLAAHRVYAEAF
Mflv_3776|M.gilvum_PYR-GCK LAPVLVVAILLRSLDAMKVFEYVFATTR---GGPGTETETLQYFIYQTGI
Mvan_2623|M.vanbaalenii_PYR-1 LAPVLVVAILLRCLDAMKVFEYVFATTR---GGPGTETETLQYFIYQTGI
TH_2010|M.thermoresistible__bu LRRFIELGAVLGAIYLVNTFDPIYMMTQ---GGPGTASSNLPFYIYQRAF
: . : : : *: : * * : :: :
Rv2835c|M.tuberculosis_H37Rv RNFRAGYGATVATIMFLVLLAVTYYQVRVMDRGQRQ------
Mb2859c|M.bovis_AF2122/97 RNFRAGYGATVATIMFLVLLAVTYYQVRVMDRGQRQ------
MMAR_1898|M.marinum_M RNFRAGYGATIATMMFLFLLVVTYYQVRVMDRGQQQ------
MUL_2126|M.ulcerans_Agy99 RNFRAGYGATIATMMFLFLLVVTYYQVRVMDRGQQQ------
MAV_2477|M.avium_104 SFLEFGYASALAWVMFAVLLVLTVVQLRVSHRRSLETSRGLK
MSMEG_0516|M.smegmatis_MC2_155 VQFDAGYAAAMAYVLFVVILVITAVQFRLARR-YVHT-----
MLBr_01768|M.leprae_Br4923 GSAAIGRASVMAVLLFVVLFGVTVVQHLYFQRRISYELT---
MAB_1717c|M.abscessus_ATCC_199 EAAHVGRSAAMSLILFLILVTITVIQHRYFRARVSYDLV---
Mflv_3776|M.gilvum_PYR-GCK QFFRLGSASSMAFVVLIVVLAAIVFAFRRMDRAREAGIR---
Mvan_2623|M.vanbaalenii_PYR-1 QFFRLGSASSMAFIVLVVVLAVIVIAFRRMERTKSR------
TH_2010|M.thermoresistible__bu LGFDIGQAAAMGVIVVIFTIIIATFALRLIFRSFTGKEEAA-
* .: :. ::. . .