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MPSLRFQHGMVAPLAALFVGVVGFPLGYAAYLSVTDYKLTDRGAPNLVGADNYVAAFSDGAFWGAFGTTA LYVLVAVGLELVIGLAIALALQKQRWAKDLTRSMLLAPMFITPIAVGLTFRFLLNDQLGAIPAMLDAIGV EYDFFGPGRALFTLAFIDVWQWTPFMVLLLLAGLESIPKEPLDAARLDGASGLYVLRRVTLPLLAPVLVV AILLRCLDAMKVFEYVFATTRGGPGTETETLQYFIYQTGIQFFRLGSASSMAFIVLVVVLAVIVIAFRRM ERTKSR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2623 | - | - | 100% (287) | binding-protein-dependent transport systems inner membrane component |
M. vanbaalenii PYR-1 | Mvan_2543 | - | 3e-36 | 30.30% (264) | binding-protein-dependent transport systems inner membrane |
M. vanbaalenii PYR-1 | Mvan_6022 | - | 1e-09 | 24.88% (217) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1268 | sugA | 7e-35 | 33.21% (277) | sugar-transport integral membrane protein ABC transporter |
M. gilvum PYR-GCK | Mflv_3776 | - | 1e-145 | 90.39% (281) | binding-protein-dependent transport systems inner membrane |
M. tuberculosis H37Rv | Rv1236 | sugA | 8e-35 | 33.21% (277) | sugar-transport integral membrane protein ABC transporter |
M. leprae Br4923 | MLBr_01087 | - | 8e-37 | 31.65% (278) | putative ABC-transport protein, inner membrane component |
M. abscessus ATCC 19977 | MAB_1373 | - | 1e-38 | 34.33% (268) | sugar ABC transporter, permease protein SugA |
M. marinum M | MMAR_4205 | sugA | 3e-36 | 32.60% (273) | sugar-transport integral membrane protein ABC transporter |
M. avium 104 | MAV_1375 | sugA | 2e-35 | 32.71% (266) | ABC transporter, permease protein SugA |
M. smegmatis MC2 155 | MSMEG_3110 | - | 1e-116 | 71.02% (283) | binding-protein-dependent transport systems inner membrane |
M. thermoresistible (build 8) | TH_4307 | - | 2e-40 | 34.07% (273) | PUTATIVE binding-protein-dependent transport systems inner |
M. ulcerans Agy99 | MUL_4512 | sugA | 3e-34 | 32.28% (254) | sugar-transport integral membrane protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment Mb1268|M.bovis_AF2122/97 ---MTSVEQRTATAVFSRTGSRMAERRLAFMLVAPAAMLMVAVTAYPIGY Rv1236|M.tuberculosis_H37Rv ---MTSVEQRTATAVFSRTGSRMAERRLAFMLVAPAAMLMVAVTAYPIGY MAV_1375|M.avium_104 --------------MLGRT----SEQRLALVLVAPAAILMLAVTAYPIGY MLBr_01087|M.leprae_Br4923 ---MTAVVG---KSWHVRASSVQPEQRLAFLLVTPAAMLMLVVTAYPIGY MMAR_4205|M.marinum_M ------------MTALMRSRGRRAERRLAFALVAPATILMLLVIGYPIGY MUL_4512|M.ulcerans_Agy99 ------------MTAFLRSRGRRAERRLAFALVAPATILMLLVIGYPIGY MAB_1373|M.abscessus_ATCC_1997 MTDRTS------------SEGKRAERRLGLLLIAPAALLMLAVTAYPICY TH_4307|M.thermoresistible__bu MTAAAEKADPTPAAAVARTDDTRSERRLAYWLIAPAVLLMVAVTGYPIAY Mvan_2623|M.vanbaalenii_PYR-1 ---------------------MMPSLRFQHGMVAPLAALFVGVVGFPLGY Mflv_3776|M.gilvum_PYR-GCK -------------------------MKFQHGMVAPLVALFVGVVGFPLGY MSMEG_3110|M.smegmatis_MC2_155 -------------------------MKFKYGMLMPLLALFAVAVGFPLCY :: :: * *: . .:*: * Mb1268|M.bovis_AF2122/97 ALWLSLQRNNLATPNDTAFIGLGNYHTILIDRYWWTALAVTLAITAVSVT Rv1236|M.tuberculosis_H37Rv ALWLSLQRNNLATPNDTAFIGLGNYHTILIDRYWWTALAVTLAITAVSVT MAV_1375|M.avium_104 AVWLSLQRNNLAAPHDTAFVGLSNYATILSDRYWWTALAVTLGITVVSVS MLBr_01087|M.leprae_Br4923 AVWLSLQRYSLATPNETVFIGLGNYQTILTDPYWWTALAVTLAITVVSVS MMAR_4205|M.marinum_M AMWLSLQRNNLATPNETRFIGLGNYQTILVDRYWWTALAVTAAITVVSVA MUL_4512|M.ulcerans_Agy99 AMWLSLQRNNLATPNETRFIGLGNYQTILVDRYWWTALAVTAAITVVSVA MAB_1373|M.abscessus_ATCC_1997 AIWLSVQKYSFASPQDRKFVWFDNYITVLSDRYWWSALVVTLVITVISVL TH_4307|M.thermoresistible__bu AVWLSLLRYNLAQPDDVSFVGLENYVTVLTDEYWWTAFAVTLGITVVSVA Mvan_2623|M.vanbaalenii_PYR-1 AAYLSVTDYKLTDRGAPNLVGADNYVAAFSDGAFWGAFGTTALYVLVAVG Mflv_3776|M.gilvum_PYR-GCK AAYLSVTDYKLTDQGAPDIVGADNFVATFGDSGFWNAFGTTALYVLVAVG MSMEG_3110|M.smegmatis_MC2_155 AAYLSVTDYKLTDREPPDFVGTANFATALSNPAFWEAFATTATYVVIAVC * :**: .:: :: *: : : : :* *: .* . ::* Mb1268|M.bovis_AF2122/97 IEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASYSWYYAWTPGT Rv1236|M.tuberculosis_H37Rv IEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASYSWYYAWTPGT MAV_1375|M.avium_104 AEFVLGLALALVMHRTLVGKGLVRTAVLIPYGIVTAVASYSWYYAWTPGT MLBr_01087|M.leprae_Br4923 IEFILGLMLALVMHRTLLGKSLVRIAVLIPYSIVTVVASYSWYYAWTPGT MMAR_4205|M.marinum_M CEFVLGLALALVMHRSLVAKGLVRTAVLVPYGIVTVVASYSWYYAWTPGT MUL_4512|M.ulcerans_Agy99 CEFVLGLALALVMHRSLVAKGLVRTAVLVPYGIVTVVASYSWYYAWTPGT MAB_1373|M.abscessus_ATCC_1997 IELVLGLALALVMHRTIFGRGVVRTAVLIPYGIVTVAASYSWYYAWTPGT TH_4307|M.thermoresistible__bu IEFVLGLALALVMHRTIFGKGVVRTAILIPYGIVTVAASYSWYYAWTPGT Mvan_2623|M.vanbaalenii_PYR-1 LELVIGLAIALALQKQRWAKDLTRSMLLAPMFITPIAVGLTFRFLLNDQL Mflv_3776|M.gilvum_PYR-GCK LELVIGLAIALALQKQRWARDLTRSMLLAPMFITPIAVGLTFRFLLNDQL MSMEG_3110|M.smegmatis_MC2_155 GELVIGFALALALHQQRWAKDLSRAIVLAPMFITPIAVGLIFRFLLNDQI *:::*: :**.::: .:.: * :* * *.. ... : : . Mb1268|M.bovis_AF2122/97 GYLANLLPYDSAPLTQQIP--SLGIVVIAEVWKTTPFMSLLLLAGLALVP Rv1236|M.tuberculosis_H37Rv GYLANLLPYDSAPLTQQIP--SLGIVVIAEVWKTTPFMSLLLLAGLALVP MAV_1375|M.avium_104 GYLANLLPHGSAPLTAQIP--SLAIVVLAEVWKTTPFMSLLLLAGLALVP MLBr_01087|M.leprae_Br4923 GYLASLLPQGSVPLTEQIP--SLSIVIIVEVWKTTPFMSLLLLVGLALVP MMAR_4205|M.marinum_M GYLANLLPQGSAPLTQQIP--SLGIVVIAEVWKTTPFMSLLLLAGLAMVP MUL_4512|M.ulcerans_Agy99 GYLANLLPQGIAPLTQQIP--SLGIVVIAEVWKTTPFMSLLLLAGLAMVP MAB_1373|M.abscessus_ATCC_1997 GYLANLLPAGSAPLTQQIP--SLAVVILAEVWKTTPFMALLLLAGLALVP TH_4307|M.thermoresistible__bu GYLANLLPDGSAPLTQQLP--SLAIVVLAEVWKTTPFMALLLLAGLALVP Mvan_2623|M.vanbaalenii_PYR-1 GAIPAMLDAIGVEYDFFGPGRALFTLAFIDVWQWTPFMVLLLLAGLESIP Mflv_3776|M.gilvum_PYR-GCK GAIPAMLHAIGIDYDFFGPGRALYTLAFIDVWQWTPFMVLLLLAGLESIP MSMEG_3110|M.smegmatis_MC2_155 GAVPALLHAVGADHDFFGSGRALLTLAFIDIWQWTPFMVLLILAGLESMP * :. :* . :* : : ::*: **** **:*.** :* Mb1268|M.bovis_AF2122/97 EDLLRAAQVDGASAWRRLTKVILPMIKPAIVVALLFRTLDAFRIFDNIYV Rv1236|M.tuberculosis_H37Rv EDLLRAAQVDGASAWRRLTKVILPMIKPAIVVALLFRTLDAFRIFDNIYV MAV_1375|M.avium_104 EDLLKAAQVDGAGAWRRLTRVTLPIIKPAVVVALLFRTLDAFRIFDNIYV MLBr_01087|M.leprae_Br4923 EDLLKAAQMDGAGAWRRLTKIILPIIKPAVMVALLFRTLDAFRIFDNIYV MMAR_4205|M.marinum_M EDLLQAAQVDGAGAWRRLTKIILPLIKPAVLVALLFRTLDAFRIFDNIYV MUL_4512|M.ulcerans_Agy99 EDLLQAAQVDGAGAWRRLTKIILPLIKPAVLVALLFRTLDAFRIFDNIYV MAB_1373|M.abscessus_ATCC_1997 DDLLKAAQVDGANGWSRLIRVTVPIMKPAILVALLFRTLDAFRIFDNIYV TH_4307|M.thermoresistible__bu QELLNAAQMDGANAWQRLVKIILPMIKPAILVALLFRTLDAFRIFDNIYI Mvan_2623|M.vanbaalenii_PYR-1 KEPLDAARLDGASGLYVLRRVTLPLLAPVLVVAILLRCLDAMKVFEYVFA Mflv_3776|M.gilvum_PYR-GCK KEPLDAARVDGARGLYVLRRVTLPLLAPVLVVAILLRSLDAMKVFEYVFA MSMEG_3110|M.smegmatis_MC2_155 KQPMEAARVDGAGPVYRLRRVLIPMLAPVLTVAVLLRGLDALRVFEYVYA .: : **::*** * :: :*:: *.: **:*:* ***:::*: :: Mb1268|M.bovis_AF2122/97 LTGGSNNTGSVSILGYDNLFKGFNVGLGSA----------------ISVL Rv1236|M.tuberculosis_H37Rv LTGGSNNTGSVSILGYDNLFKGFNVGLGSA----------------ISVL MAV_1375|M.avium_104 LTNGANNTGSVSMLGYDNLFKGFNVGLGSA----------------ISVL MLBr_01087|M.leprae_Br4923 LTRGVNNTDSVSILGYDNLFKGFNVGLGSA----------------ISVL MMAR_4205|M.marinum_M LTGGDNDTASVSILGYDNLFKGFNVGLGSA----------------ISVL MUL_4512|M.ulcerans_Agy99 LTGGDNDTASVSILGYDNLFKGFNVGLAVQGIQCGPRFGDQRVDLRLCHS MAB_1373|M.abscessus_ATCC_1997 LTGGSNNTGSVSILGYDNLFKAFNVGLGSA----------------ISVL TH_4307|M.thermoresistible__bu LTGGANNTGSVSILGYNNLFKAFNLGLGSA----------------ISVL Mvan_2623|M.vanbaalenii_PYR-1 TTRGGPGTETETLQYFIYQTGIQFFRLGSA-----------------SSM Mflv_3776|M.gilvum_PYR-GCK TTRGGPGTETETLQYFIYQTGIQFFRLGSA-----------------SSM MSMEG_3110|M.smegmatis_MC2_155 TTRGGPGTETQTLQYYMYLEGIQFFRLAQA-----------------SAM * * .* : :: : . *. . Mb1268|M.bovis_AF2122/97 IFGCVAVIAFIFIKLFGA----AAPGGEPSGR------------------ Rv1236|M.tuberculosis_H37Rv IFGCVAVIAFIFIKLFGA----AAPGGEPSGR------------------ MAV_1375|M.avium_104 IFGCVGLIALVFVKVFGA----AAPGGDVDGR------------------ MLBr_01087|M.leprae_Br4923 IFGCVALIAVIFIKVFGV----VAPGGDSNGY------------------ MMAR_4205|M.marinum_M IFGCVTLIAVVFITLFGAHQFHSAPGGVTDAR------------------ MUL_4512|M.ulcerans_Agy99 HCGCLHHAVRRPSIRFCARWCDRCALRLGPCRRVAGGERSGWPSTPWSWS MAB_1373|M.abscessus_ATCC_1997 IFLCVAIIAVIFIKGFGA----SAPTTDGEEARR---------------- TH_4307|M.thermoresistible__bu IFLCVAVIAFIYIKIFGT----SAPGSDAERS------------------ Mvan_2623|M.vanbaalenii_PYR-1 AFIVLVVVLAVIVIAFRR----MERTKSR--------------------- Mflv_3776|M.gilvum_PYR-GCK AFVVLIVVLAAIVFAFRR----MDRAREAGIR------------------ MSMEG_3110|M.smegmatis_MC2_155 AFIVLVLVLAVIVVAFRT----MERTRERTPSR----------------- : * Mb1268|M.bovis_AF2122/97 --------- Rv1236|M.tuberculosis_H37Rv --------- MAV_1375|M.avium_104 --------- MLBr_01087|M.leprae_Br4923 --------- MMAR_4205|M.marinum_M --------- MUL_4512|M.ulcerans_Agy99 TPCSRCCGS MAB_1373|M.abscessus_ATCC_1997 --------- TH_4307|M.thermoresistible__bu --------- Mvan_2623|M.vanbaalenii_PYR-1 --------- Mflv_3776|M.gilvum_PYR-GCK --------- MSMEG_3110|M.smegmatis_MC2_155 ---------