For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. gilvum PYR-GCK Mflv_3776 (-)

annotation: binding-protein-dependent transport systems inner membrane component
coordinates: 4031428 - 4032288
length: 286

VKFQHGMVAPLVALFVGVVGFPLGYAAYLSVTDYKLTDQGAPDIVGADNFVATFGDSGFWNAFGTTALYV
LVAVGLELVIGLAIALALQKQRWARDLTRSMLLAPMFITPIAVGLTFRFLLNDQLGAIPAMLHAIGIDYD
FFGPGRALYTLAFIDVWQWTPFMVLLLLAGLESIPKEPLDAARVDGARGLYVLRRVTLPLLAPVLVVAIL
LRSLDAMKVFEYVFATTRGGPGTETETLQYFIYQTGIQFFRLGSASSMAFVVLIVVLAAIVFAFRRMDRA
REAGIR

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. gilvum PYR-GCK Mflv_3776 - - 100% (286) binding-protein-dependent transport systems inner membrane component
M. gilvum PYR-GCK Mflv_3852 - 1e-36 30.60% (281) binding-protein-dependent transport systems inner membrane
M. gilvum PYR-GCK Mflv_3777 - 6e-10 25.89% (282) binding-protein-dependent transport systems inner membrane

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb1268 sugA 1e-33 30.94% (278) sugar-transport integral membrane protein ABC transporter
M. tuberculosis H37Rv Rv2835c ugpA 2e-34 33.45% (278) sn-glycerol-3-phosphate transport integral membrane protein
M. leprae Br4923 MLBr_01087 - 3e-34 28.84% (267) putative ABC-transport protein, inner membrane component
M. abscessus ATCC 19977 MAB_1373 - 1e-37 32.58% (267) sugar ABC transporter, permease protein SugA
M. marinum M MMAR_4205 sugA 2e-35 31.84% (267) sugar-transport integral membrane protein ABC transporter
M. avium 104 MAV_1375 sugA 1e-34 32.96% (267) ABC transporter, permease protein SugA
M. smegmatis MC2 155 MSMEG_3110 - 1e-116 70.21% (282) binding-protein-dependent transport systems inner membrane
M. thermoresistible (build 8) TH_2010 - 4e-41 31.29% (278) sugar ABC transporter permease protein
M. ulcerans Agy99 MUL_4512 sugA 3e-33 32.13% (249) sugar-transport integral membrane protein ABC transporter
M. vanbaalenii PYR-1 Mvan_2623 - 1e-145 90.39% (281) binding-protein-dependent transport systems inner membrane

CLUSTAL 2.0.9 multiple sequence alignment


Mb1268|M.bovis_AF2122/97            -------------MTSVEQRTATAVFSRTGSRMAERRLAFMLVAPAAMLM
MAV_1375|M.avium_104                ------------------------MLGRT----SEQRLALVLVAPAAILM
MLBr_01087|M.leprae_Br4923          -------------MTAVVG---KSWHVRASSVQPEQRLAFLLVTPAAMLM
MMAR_4205|M.marinum_M               ----------------------MTALMRSRGRRAERRLAFALVAPATILM
MUL_4512|M.ulcerans_Agy99           ----------------------MTAFLRSRGRRAERRLAFALVAPATILM
MAB_1373|M.abscessus_ATCC_1997      ----------------------MTDRTSSEGKRAERRLGLLLIAPAALLM
Mflv_3776|M.gilvum_PYR-GCK          --------------------MKFQHG---------------MVAPLVALF
Mvan_2623|M.vanbaalenii_PYR-1       ----------------MMPSLRFQHG---------------MVAPLAALF
MSMEG_3110|M.smegmatis_MC2_155      --------------------MKFKYG---------------MLMPLLALF
Rv2835c|M.tuberculosis_H37Rv        --------------MAAPQRARLRSSKERVRDYAL---FVVLVGPNVALL
TH_2010|M.thermoresistible__bu      MTAIAPGASEHLTGSEADRVARIKHAKQQGVSRAEGWRRRGPLLPALIFM
                                                                              : *   ::

Mb1268|M.bovis_AF2122/97            VAVTAYPIGYALWLSLQRNNLATPNDTAFIGLGNYHTILIDRYWWTALAV
MAV_1375|M.avium_104                LAVTAYPIGYAVWLSLQRNNLAAPHDTAFVGLSNYATILSDRYWWTALAV
MLBr_01087|M.leprae_Br4923          LVVTAYPIGYAVWLSLQRYSLATPNETVFIGLGNYQTILTDPYWWTALAV
MMAR_4205|M.marinum_M               LLVIGYPIGYAMWLSLQRNNLATPNETRFIGLGNYQTILVDRYWWTALAV
MUL_4512|M.ulcerans_Agy99           LLVIGYPIGYAMWLSLQRNNLATPNETRFIGLGNYQTILVDRYWWTALAV
MAB_1373|M.abscessus_ATCC_1997      LAVTAYPICYAIWLSVQKYSFASPQDRKFVWFDNYITVLSDRYWWSALVV
Mflv_3776|M.gilvum_PYR-GCK          VGVVGFPLGYAAYLSVTDYKLTDQGAPDIVGADNFVATFGDSGFWNAFGT
Mvan_2623|M.vanbaalenii_PYR-1       VGVVGFPLGYAAYLSVTDYKLTDRGAPNLVGADNYVAAFSDGAFWGAFGT
MSMEG_3110|M.smegmatis_MC2_155      AVAVGFPLCYAAYLSVTDYKLTDREPPDFVGTANFATALSNPAFWEAFAT
Rv2835c|M.tuberculosis_H37Rv        LLFVYRPLADNIRLSFFDWNVSDPSAR-FVGLSNYTEWFTRSDTRQIVFN
TH_2010|M.thermoresistible__bu      IIVTQVPFLFTLYFSTLSWNLVRPGSREFVGFQNYVDVVQDSTFWQVAVN
                                          *:     :*    ..       ::   *:   .           

Mb1268|M.bovis_AF2122/97            TLAITAVSVTIEFVLGLALALVMHRTLIGKGLVRTAVLIPYGIVTVVASY
MAV_1375|M.avium_104                TLGITVVSVSAEFVLGLALALVMHRTLVGKGLVRTAVLIPYGIVTAVASY
MLBr_01087|M.leprae_Br4923          TLAITVVSVSIEFILGLMLALVMHRTLLGKSLVRIAVLIPYSIVTVVASY
MMAR_4205|M.marinum_M               TAAITVVSVACEFVLGLALALVMHRSLVAKGLVRTAVLVPYGIVTVVASY
MUL_4512|M.ulcerans_Agy99           TAAITVVSVACEFVLGLALALVMHRSLVAKGLVRTAVLVPYGIVTVVASY
MAB_1373|M.abscessus_ATCC_1997      TLVITVISVLIELVLGLALALVMHRTIFGRGVVRTAVLIPYGIVTVAASY
Mflv_3776|M.gilvum_PYR-GCK          TALYVLVAVGLELVIGLAIALALQKQRWARDLTRSMLLAPMFITPIAVGL
Mvan_2623|M.vanbaalenii_PYR-1       TALYVLVAVGLELVIGLAIALALQKQRWAKDLTRSMLLAPMFITPIAVGL
MSMEG_3110|M.smegmatis_MC2_155      TATYVVIAVCGELVIGFALALALHQQRWAKDLSRAIVLAPMFITPIAVGL
Rv2835c|M.tuberculosis_H37Rv        TAVFTGAAVVGSMVLGLALAMLLDRPLRGRNLVRSTVFAPFVISGAAVGL
TH_2010|M.thermoresistible__bu      SVLIIVVTVLVSVLLGLGLALLLDRVFLGRGIVRTLLITPFLVTPVAGAL
                                    :      :*  ..::*: :*: :.:   .:.: *  :: *  :   . . 

Mb1268|M.bovis_AF2122/97            SWY-YAWTPGTGYLANLLPYDSAPLTQQIPSLG----IVVIAEVWKTTPF
MAV_1375|M.avium_104                SWY-YAWTPGTGYLANLLPHGSAPLTAQIPSLA----IVVLAEVWKTTPF
MLBr_01087|M.leprae_Br4923          SWY-YAWTPGTGYLASLLPQGSVPLTEQIPSLS----IVIIVEVWKTTPF
MMAR_4205|M.marinum_M               SWY-YAWTPGTGYLANLLPQGSAPLTQQIPSLG----IVVIAEVWKTTPF
MUL_4512|M.ulcerans_Agy99           SWY-YAWTPGTGYLANLLPQGIAPLTQQIPSLG----IVVIAEVWKTTPF
MAB_1373|M.abscessus_ATCC_1997      SWY-YAWTPGTGYLANLLPAGSAPLTQQIPSLA----VVILAEVWKTTPF
Mflv_3776|M.gilvum_PYR-GCK          TFR-FLLNDQLGAIPAMLHAIGIDY-DFFGPGR-ALYTLAFIDVWQWTPF
Mvan_2623|M.vanbaalenii_PYR-1       TFR-FLLNDQLGAIPAMLDAIGVEY-DFFGPGR-ALFTLAFIDVWQWTPF
MSMEG_3110|M.smegmatis_MC2_155      IFR-FLLNDQIGAVPALLHAVGADH-DFFGSGR-ALLTLAFIDIWQWTPF
Rv2835c|M.tuberculosis_H37Rv        AAQ-FVFDPHFGLIQDLLRRIGVGVPDFYQDARWALFMVTITYVWKNLGY
TH_2010|M.thermoresistible__bu      MWKTAMLDPVFGIVNWLLSPFGVHQVDWVSRFP--LTSVMINLVWQWTPF
                                               * :  :*                    : :  :*:   :

Mb1268|M.bovis_AF2122/97            MSLLLLAGLALVPEDLLRAAQVDGASAWRRLTKVILPMIKPAIVVALLFR
MAV_1375|M.avium_104                MSLLLLAGLALVPEDLLKAAQVDGAGAWRRLTRVTLPIIKPAVVVALLFR
MLBr_01087|M.leprae_Br4923          MSLLLLVGLALVPEDLLKAAQMDGAGAWRRLTKIILPIIKPAVMVALLFR
MMAR_4205|M.marinum_M               MSLLLLAGLAMVPEDLLQAAQVDGAGAWRRLTKIILPLIKPAVLVALLFR
MUL_4512|M.ulcerans_Agy99           MSLLLLAGLAMVPEDLLQAAQVDGAGAWRRLTKIILPLIKPAVLVALLFR
MAB_1373|M.abscessus_ATCC_1997      MALLLLAGLALVPDDLLKAAQVDGANGWSRLIRVTVPIMKPAILVALLFR
Mflv_3776|M.gilvum_PYR-GCK          MVLLLLAGLESIPKEPLDAARVDGARGLYVLRRVTLPLLAPVLVVAILLR
Mvan_2623|M.vanbaalenii_PYR-1       MVLLLLAGLESIPKEPLDAARLDGASGLYVLRRVTLPLLAPVLVVAILLR
MSMEG_3110|M.smegmatis_MC2_155      MVLLILAGLESMPKQPMEAARVDGAGPVYRLRRVLIPMLAPVLTVAVLLR
Rv2835c|M.tuberculosis_H37Rv        TFVIYLAALQGVRRDLLEAAEIDGASRWAVFRRVLLPQLRPTTFFLSITV
TH_2010|M.thermoresistible__bu      MMLLILAGLQSMPRDILEAGRVDGAGTFQLFRELTLPHLRRFIELGAVLG
                                      :: *..*  :  : : *..:***     : .: :* :     .  :  

Mb1268|M.bovis_AF2122/97            TLDAFRIFDNIYVLTGGSN---NTGSVSILGYDNLFKGFNVGLGSA----
MAV_1375|M.avium_104                TLDAFRIFDNIYVLTNGAN---NTGSVSMLGYDNLFKGFNVGLGSA----
MLBr_01087|M.leprae_Br4923          TLDAFRIFDNIYVLTRGVN---NTDSVSILGYDNLFKGFNVGLGSA----
MMAR_4205|M.marinum_M               TLDAFRIFDNIYVLTGGDN---DTASVSILGYDNLFKGFNVGLGSA----
MUL_4512|M.ulcerans_Agy99           TLDAFRIFDNIYVLTGGDN---DTASVSILGYDNLFKGFNVGLAVQGIQC
MAB_1373|M.abscessus_ATCC_1997      TLDAFRIFDNIYVLTGGSN---NTGSVSILGYDNLFKAFNVGLGSA----
Mflv_3776|M.gilvum_PYR-GCK          SLDAMKVFEYVFATTRGGP-GTETETLQYFIYQTGIQFFRLGSASS----
Mvan_2623|M.vanbaalenii_PYR-1       CLDAMKVFEYVFATTRGGP-GTETETLQYFIYQTGIQFFRLGSASS----
MSMEG_3110|M.smegmatis_MC2_155      GLDALRVFEYVYATTRGGP-GTETQTLQYYMYLEGIQFFRLAQASA----
Rv2835c|M.tuberculosis_H37Rv        LINSLQVFDVINVMTRGGPEGTGTTTMVYQVYVETFRNFRAGYGAT----
TH_2010|M.thermoresistible__bu      AIYLVNTFDPIYMMTQGGP-GTASSNLPFYIYQRAFLGFDIGQAAA----
                                     :  .. *: :   * *      : .:    *   :  *  . .      

Mb1268|M.bovis_AF2122/97            ------------ISVLIFGCVAVIAFIFIKLFGA----AAPGGEPSGR--
MAV_1375|M.avium_104                ------------ISVLIFGCVGLIALVFVKVFGA----AAPGGDVDGR--
MLBr_01087|M.leprae_Br4923          ------------ISVLIFGCVALIAVIFIKVFGV----VAPGGDSNGY--
MMAR_4205|M.marinum_M               ------------ISVLIFGCVTLIAVVFITLFGAHQFHSAPGGVTDAR--
MUL_4512|M.ulcerans_Agy99           GPRFGDQRVDLRLCHSHCGCLHHAVRRPSIRFCARWCDRCALRLGPCRRV
MAB_1373|M.abscessus_ATCC_1997      ------------ISVLIFLCVAIIAVIFIKGFGAS--APTTDGEEARR--
Mflv_3776|M.gilvum_PYR-GCK          -----------------MAFVVLIVVLAAIVFAFRRMDRAREAGIR----
Mvan_2623|M.vanbaalenii_PYR-1       -----------------MAFIVLVVVLAVIVIAFRRMERTKSR-------
MSMEG_3110|M.smegmatis_MC2_155      -----------------MAFIVLVLVLAVIVVAFRTMERTRERTPSR---
Rv2835c|M.tuberculosis_H37Rv        -----------------VATIMFLVLLAVTYYQVRVMDRGQRQ-------
TH_2010|M.thermoresistible__bu      -----------------MGVIVVIFTIIIATFALRLIFRSFTGKEEAA--
                                                        :                             

Mb1268|M.bovis_AF2122/97            -------------------------
MAV_1375|M.avium_104                -------------------------
MLBr_01087|M.leprae_Br4923          -------------------------
MMAR_4205|M.marinum_M               -------------------------
MUL_4512|M.ulcerans_Agy99           AGGERSGWPSTPWSWSTPCSRCCGS
MAB_1373|M.abscessus_ATCC_1997      -------------------------
Mflv_3776|M.gilvum_PYR-GCK          -------------------------
Mvan_2623|M.vanbaalenii_PYR-1       -------------------------
MSMEG_3110|M.smegmatis_MC2_155      -------------------------
Rv2835c|M.tuberculosis_H37Rv        -------------------------
TH_2010|M.thermoresistible__bu      -------------------------

species	id	gene	e-value	identity (len)	annotation
M. gilvum PYR-GCK	Mflv_3776	-	-	100% (286)	binding-protein-dependent transport systems inner membrane component
M. gilvum PYR-GCK	Mflv_3852	-	1e-36	30.60% (281)	binding-protein-dependent transport systems inner membrane
M. gilvum PYR-GCK	Mflv_3777	-	6e-10	25.89% (282)	binding-protein-dependent transport systems inner membrane