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MCAHFNTSMTNTGDDTEQSDEVGSISRLRGRKTHRTRALTKNHPRSIALAYALLAPSLFGVVTFLLLPII VVIWLSLFRWDLLGPLHYVGLANWRSVLTDPNFANSLIVTAVFVAIVVPTQTMLGLLIATMLARQLPGTG VFRTLYVLPWICAPLAIAVLWRWLLAPTDGAFSMVLRHRIEWLSDPSLALPVVSAVVVWTNVGYVSLSFL AGLLSIPEDINAAARTDGADAWQRFWRITLPMLRPTMFFVLVTGIVSTAQVFDTVYALTDGGPKSRTDLV AHRIYAEAFGSAAIGRASVMAVLLFVVLFGVTVVQHLYFQRRISYELT
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_01768 | uspA | - | 100% (328) | sugar transport integral membrane protein |
M. leprae Br4923 | MLBr_01426 | - | 1e-40 | 32.46% (305) | putative ABC-transport protein, inner membrane component |
M. leprae Br4923 | MLBr_01087 | - | 6e-35 | 30.22% (268) | putative ABC-transport protein, inner membrane component |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2343 | uspA | 1e-138 | 83.80% (284) | sugar-transport integral membrane protein ABC transporter |
M. gilvum PYR-GCK | Mflv_3852 | - | 3e-33 | 28.67% (279) | binding-protein-dependent transport systems inner membrane |
M. tuberculosis H37Rv | Rv2316 | uspA | 1e-137 | 83.45% (284) | sugar-transport integral membrane protein ABC transporter |
M. abscessus ATCC 19977 | MAB_1717c | - | 1e-117 | 68.90% (283) | sugar ABC transporter, permease protein |
M. marinum M | MMAR_3617 | uspA | 1e-135 | 81.34% (284) | sugar-transport integral membrane protein ABC transporter |
M. avium 104 | MAV_2090 | uspA | 1e-139 | 84.91% (285) | ABC transporter, permease protein UspA |
M. smegmatis MC2 155 | MSMEG_4466 | - | 1e-132 | 80.28% (284) | ABC transporter, permease protein UspA |
M. thermoresistible (build 8) | TH_4307 | - | 3e-35 | 31.75% (274) | PUTATIVE binding-protein-dependent transport systems inner |
M. ulcerans Agy99 | MUL_1248 | uspA | 1e-135 | 81.34% (284) | sugar-transport integral membrane protein ABC transporter |
M. vanbaalenii PYR-1 | Mvan_2543 | - | 2e-34 | 28.28% (297) | binding-protein-dependent transport systems inner membrane |
CLUSTAL 2.0.9 multiple sequence alignment Mb2343|M.bovis_AF2122/97 --------------------------------------MRDAPRRRTALA Rv2316|M.tuberculosis_H37Rv --------------------------------------MRDAPRRRTALA MLBr_01768|M.leprae_Br4923 MCAHFNTSMTNTGDDTEQSDEVGSISRLRGRKTHRTRALTKNHPRSIALA MAV_2090|M.avium_104 ----------------------------------MASAERRVAPRSTALG MMAR_3617|M.marinum_M --------------------------------------MRATPRRTTALA MUL_1248|M.ulcerans_Agy99 --------------------------------------MRATPRRTTALA MSMEG_4466|M.smegmatis_MC2_155 -----------------------MAPWRLLTANRFNEPMATPRVRTTALA MAB_1717c|M.abscessus_ATCC_199 ----------------------------------------MSRSRQTAVA Mflv_3852|M.gilvum_PYR-GCK ---------------------MTAPADAPIQKDPGKPSVSERAKGERRLG Mvan_2543|M.vanbaalenii_PYR-1 ---------------------MTALHEAPIQKDPGTPAVSERARGERRLG TH_4307|M.thermoresistible__bu ---------------------MTAAAEKADPTPAAAVARTDDTRSERRLA :. Mb2343|M.bovis_AF2122/97 YALLAPSLVGVVAFLLLPILVVVWLSLHRWDLLGP--LRYVGLTNWRSVL Rv2316|M.tuberculosis_H37Rv YALLAPSLVGVVAFLLLPILVVVWLSLHRWDLLGP--LRYVGLTNWRSVL MLBr_01768|M.leprae_Br4923 YALLAPSLFGVVTFLLLPIIVVIWLSLFRWDLLGP--LHYVGLANWRSVL MAV_2090|M.avium_104 YALLAPSLFGVLAFLLLPILVVIWLSLCRWDLLGP--LRFVGLSNWRSVL MMAR_3617|M.marinum_M YALLAPSLFGVLAFLLLPILVVIWLSLYRWDLLGP--LRYVGLANWRSVL MUL_1248|M.ulcerans_Agy99 YALLAPSLFGVLAFLLLPILVVIWLSLYRWDLLGP--LRYVGLANWRSVL MSMEG_4466|M.smegmatis_MC2_155 YALVAPSLFGVVTFLLLPMLVVVWLSLHRWDLLGP--IEFVGLDNWTSVL MAB_1717c|M.abscessus_ATCC_199 YGLLAPSLFGVAAFLLLPILVVVWLSLCRWDLLGP--IEFVGLDNWRSVL Mflv_3852|M.gilvum_PYR-GCK LYLTLPSYVVMLLVTAYPLGYALVLSLYNFRLTDPEGRSFVGLGNYLVIL Mvan_2543|M.vanbaalenii_PYR-1 IYLTLPSYVVMLLVTAYPLGYALVLSLYNFRLTDPEGRSFVGLSNYLVIL TH_4307|M.thermoresistible__bu YWLIAPAVLLMVAVTGYPIAYAVWLSLLRYNLAQPDDVSFVGLENYVTVL * *: . : . *: .: *** .: * * :*** *: :* Mb2343|M.bovis_AF2122/97 TDSGFADSLVVTAVFVAIVVPAQTVLGLLAASLLARRLPGTGLFRTLYVL Rv2316|M.tuberculosis_H37Rv TDSGFADSLVVTAVFVAIVVPAQTVLGLLAASLLARRLPGTGLFRTLYVL MLBr_01768|M.leprae_Br4923 TDPNFANSLIVTAVFVAIVVPTQTMLGLLIATMLARQLPGTGVFRTLYVL MAV_2090|M.avium_104 TDAGFGNSLMVTAVFVAMVVPAQTALGLLAATMLARRLPGTGLFRTVYVL MMAR_3617|M.marinum_M RDGDFGNSLVVTAIFVAIVVPAQTVLGLLAAMMLTRRLPGTNFFRTLYVL MUL_1248|M.ulcerans_Agy99 RDGDFGNSLVVTAIFVAIVVPAQTVLGLLAAMMLTRRLPGTNFFRTLYVL MSMEG_4466|M.smegmatis_MC2_155 TDPAFGKSLVVTLLFMALVVPTQTVLGLVAATMLARGLPGTGFFRTVYVL MAB_1717c|M.abscessus_ATCC_199 TDGTFGHSLLVTLLFVALVIPVQTALGLAAATLLVRGLPGTVLFRTIYVI Mflv_3852|M.gilvum_PYR-GCK TDPIWWNDFVTTLAITVVTVAIELVLGFWFAFVMLRIVRGRGPLRTAILI Mvan_2543|M.vanbaalenii_PYR-1 TDPLWWNDFVTTLAITVVTVAIELVLGFWFAFVMLRIVRGRGPLRTAILI TH_4307|M.thermoresistible__bu TDEYWWTAFAVTLGITVVSVAIEFVLGLALALVMHRTIFGKGVVRTAILI * : : .* : .: :. : **: * :: * : * .** :: Mb2343|M.bovis_AF2122/97 PWICAPLAIAVMWRWILAPTDGAISTVLG-HRIEWLTDPGLALPVVSAVV Rv2316|M.tuberculosis_H37Rv PWICAPLAIAVMWRWIVAPTDGAISTVLG-HRIEWLTDPGLALPVVSAVV MLBr_01768|M.leprae_Br4923 PWICAPLAIAVLWRWLLAPTDGAFSMVLR-HRIEWLSDPSLALPVVSAVV MAV_2090|M.avium_104 PWICAPLAIAVLWRWILAPTDGAVSAVLG-HSIEWLSDPSFALPLVSAVV MMAR_3617|M.marinum_M PWICAPLAIAVMWRWILAPTDGAISTLLG-RRIEWLTDPDLALPVVAAVV MUL_1248|M.ulcerans_Agy99 PWICAPLAIAVMWRWILAPTDGAISTLLG-RRIEWLTDPDLALPVVAAVV MSMEG_4466|M.smegmatis_MC2_155 PWICAPLAIAVLWRWILAPTDGALSTVLG-TRIEWLTDPSLALPVVSAVV MAB_1717c|M.abscessus_ATCC_199 PWICAPLAIGVLWHWMLAPTDGAVNALLG-QRVEWLTDPSLALPVVAAVS Mflv_3852|M.gilvum_PYR-GCK PYGIVTVVSAFIWRYAFAIDSGFVNQWLNLTDFDWFGDRWSAIFVICLSE Mvan_2543|M.vanbaalenii_PYR-1 PYGIVTVVSAFIWRYAFAIDSGFVNQWLNLTEFDWFGDRWSAIFVICLSE TH_4307|M.thermoresistible__bu PYGIVTVAASYSWYYAWTPGTGYLANLLPDGSAPLT-QQLPSLAIVVLAE *: ..:. . * : : * . * : :: :: Mb2343|M.bovis_AF2122/97 VWTNVGYVSLFFLAGLMAIPQDIHNAARTDGASAWQRFWRITLPMLRPTM Rv2316|M.tuberculosis_H37Rv VWTNVGYVSLFFLAGLMAIPQDIHNAARTDGASAWQRFWRITLPMLRPTM MLBr_01768|M.leprae_Br4923 VWTNVGYVSLSFLAGLLSIPEDINAAARTDGADAWQRFWRITLPMLRPTM MAV_2090|M.avium_104 VWTNVGYVSLSFLAGLLAIPEDIHAAARTDGANAWQRFWRITMPMLRPTT MMAR_3617|M.marinum_M IWTNVGYVSLSFLAGLLAIPDDIHAAARTDGANAWQRFWRITLPMLRPTT MUL_1248|M.ulcerans_Agy99 IWTNVGYVSLSFLAGLLAIPDDIHAAARTDGANAWQRFWRITLPMLRPTT MSMEG_4466|M.smegmatis_MC2_155 VWTNVGYVTLFFLAGILNIPADLHNAARTDGADAWQRFRHITLPMLRPTM MAB_1717c|M.abscessus_ATCC_199 VWTNVGYVALFFMAGLLAIPGDVHNAARVDGATAWQRFRRITLPMLRPTF Mflv_3852|M.gilvum_PYR-GCK IWKTTPFISLLLLAGLVQVPEDMQEAAKVDGATAWQRLWKITLPNMKAAI Mvan_2543|M.vanbaalenii_PYR-1 IWKTTPFISLLLLAGLVQVPEDMQEAAKVDGATAWQRLWKITLPNMKAAI TH_4307|M.thermoresistible__bu VWKTTPFMALLLLAGLALVPQELLNAAQMDGANAWQRLVKIILPMIKPAI :*... :::* ::**: :* :: **: *** ****: :* :* ::.: Mb2343|M.bovis_AF2122/97 FFVLVTGIISAAQVFDTVYALTGGGPQGSTDLVAHRIYAEAFGAAAIGRA Rv2316|M.tuberculosis_H37Rv FFVLVTGIISAAQVFDTVYALTGGGPQGSTDLVAHRIYAEAFGAAAIGRA MLBr_01768|M.leprae_Br4923 FFVLVTGIVSTAQVFDTVYALTDGGPKSRTDLVAHRIYAEAFGSAAIGRA MAV_2090|M.avium_104 FFVLVTGIVSSAQVFDTVYALTGGGPAGSTDLVAHRIYAEAFGSAAIGRA MMAR_3617|M.marinum_M FFVLVTGIVSAAQIFDIVYALTGGGPEGSTELVAHQIYAEAFGSAAIGRA MUL_1248|M.ulcerans_Agy99 FFVLVTGIVSAAQIFDIVYALTGGGPEGSTELVAHQIYAEAFGSAAIGRA MSMEG_4466|M.smegmatis_MC2_155 FFVLVTGIVSAAQVFDTVYALTAGGPQGRTDLIAHRIYAEAFGAAAVGRA MAB_1717c|M.abscessus_ATCC_199 FFVLVTGVVSAVQTFDTVYALTSGGPQNRTDLAAHRVYAEAFEAAHVGRS Mflv_3852|M.gilvum_PYR-GCK MVALLFRTLDAWRIFDNPYVMTAG--ANNTETISFLAYRQNVTLVNLGMG Mvan_2543|M.vanbaalenii_PYR-1 MVALLFRTLDAWRIFDNPYVMTAG--ANNTETISFLAYRQNVTLVNLGMG TH_4307|M.thermoresistible__bu LVALLFRTLDAFRIFDNIYILTGG--ANNTGSVSILGYNNLFKAFNLGLG :..*: :.: : ** * :* * . * : * : . :* . Mb2343|M.bovis_AF2122/97 SVMAVVLFVILVGATVVQHLYFRRRISYELT--- Rv2316|M.tuberculosis_H37Rv SVMAVVLFVILVGATVVQHLYFRRRISYELT--- MLBr_01768|M.leprae_Br4923 SVMAVLLFVVLFGVTVVQHLYFQRRISYELT--- MAV_2090|M.avium_104 SVMAVVLFVILIGVTLVQHLYFRRRISYDLT--- MMAR_3617|M.marinum_M SVMAVVLFVILIGVTFVQHMYFRRRISYDLT--- MUL_1248|M.ulcerans_Agy99 SVMAVVLFVILIGVTFVQHMYFRRRISYDLT--- MSMEG_4466|M.smegmatis_MC2_155 AVMALVLFVLLVGVTIVQHLYFRRRISYELT--- MAB_1717c|M.abscessus_ATCC_199 AAMSLILFLILVTITVIQHRYFRARVSYDLV--- Mflv_3852|M.gilvum_PYR-GCK SAVSVLLFLSVVAIAWIFIKVFKTDLSQVRGDQ- Mvan_2543|M.vanbaalenii_PYR-1 SAVSVLLFLSVVGIAWIFIKVFKTDLSQVRGDQ- TH_4307|M.thermoresistible__bu SAISVLIFLCVAVIAFIYIKIFGTSAPGSDAERS :.:::::*: : : : * .