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M. tuberculosis H37Rv Rv2316 (uspA)

annotation: PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPA
coordinates: 2588838 - 2589710
length: 290

MRDAPRRRTALAYALLAPSLVGVVAFLLLPILVVVWLSLHRWDLLGPLRYVGLTNWRSVLTDSGFADSLV
VTAVFVAIVVPAQTVLGLLAASLLARRLPGTGLFRTLYVLPWICAPLAIAVMWRWIVAPTDGAISTVLGH
RIEWLTDPGLALPVVSAVVVWTNVGYVSLFFLAGLMAIPQDIHNAARTDGASAWQRFWRITLPMLRPTMF
FVLVTGIISAAQVFDTVYALTGGGPQGSTDLVAHRIYAEAFGAAAIGRASVMAVVLFVILVGATVVQHLY
FRRRISYELT
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2316uspA-100% (290)PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPA
M. tuberculosis H37RvRv2040c-2e-4435.29% (289) sugar-transport integral membrane protein ABC transporter
M. tuberculosis H37RvRv2835cugpA7e-3933.81% (278) sn-glycerol-3-phosphate transport integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2343uspA1e-16499.66% (290) sugar-transport integral membrane protein ABC transporter
M. gilvum PYR-GCKMflv_3852-7e-3329.03% (279) binding-protein-dependent transport systems inner membrane
M. leprae Br4923MLBr_01768uspA1e-13883.45% (284) sugar transport integral membrane protein
M. abscessus ATCC 19977MAB_1717c-1e-12372.79% (283) sugar ABC transporter, permease protein
M. marinum MMMAR_3617uspA1e-14385.17% (290) sugar-transport integral membrane protein ABC transporter
M. avium 104MAV_2090uspA1e-14285.12% (289) ABC transporter, permease protein UspA
M. smegmatis MC2 155MSMEG_4466-1e-13782.75% (284) ABC transporter, permease protein UspA
M. thermoresistible (build 8)TH_4307-3e-3933.69% (282) PUTATIVE binding-protein-dependent transport systems inner
M. ulcerans Agy99MUL_1248uspA1e-14385.17% (290) sugar-transport integral membrane protein ABC transporter
M. vanbaalenii PYR-1Mvan_2543-3e-3429.23% (284) binding-protein-dependent transport systems inner membrane

CLUSTAL 2.0.9 multiple sequence alignment


Rv2316|M.tuberculosis_H37Rv         --------------------------------------MRDAPRRRTALA
Mb2343|M.bovis_AF2122/97            --------------------------------------MRDAPRRRTALA
MMAR_3617|M.marinum_M               --------------------------------------MRATPRRTTALA
MUL_1248|M.ulcerans_Agy99           --------------------------------------MRATPRRTTALA
MLBr_01768|M.leprae_Br4923          MCAHFNTSMTNTGDDTEQSDEVGSISRLRGRKTHRTRALTKNHPRSIALA
MAV_2090|M.avium_104                ----------------------------------MASAERRVAPRSTALG
MSMEG_4466|M.smegmatis_MC2_155      -----------------------MAPWRLLTANRFNEPMATPRVRTTALA
MAB_1717c|M.abscessus_ATCC_199      ----------------------------------------MSRSRQTAVA
Mflv_3852|M.gilvum_PYR-GCK          ---------------------MTAPADAPIQKDPGKPSVSERAKGERRLG
Mvan_2543|M.vanbaalenii_PYR-1       ---------------------MTALHEAPIQKDPGTPAVSERARGERRLG
TH_4307|M.thermoresistible__bu      ---------------------MTAAAEKADPTPAAAVARTDDTRSERRLA
                                                                                    :.

Rv2316|M.tuberculosis_H37Rv         YALLAPSLVGVVAFLLLPILVVVWLSLHRWDLLGP--LRYVGLTNWRSVL
Mb2343|M.bovis_AF2122/97            YALLAPSLVGVVAFLLLPILVVVWLSLHRWDLLGP--LRYVGLTNWRSVL
MMAR_3617|M.marinum_M               YALLAPSLFGVLAFLLLPILVVIWLSLYRWDLLGP--LRYVGLANWRSVL
MUL_1248|M.ulcerans_Agy99           YALLAPSLFGVLAFLLLPILVVIWLSLYRWDLLGP--LRYVGLANWRSVL
MLBr_01768|M.leprae_Br4923          YALLAPSLFGVVTFLLLPIIVVIWLSLFRWDLLGP--LHYVGLANWRSVL
MAV_2090|M.avium_104                YALLAPSLFGVLAFLLLPILVVIWLSLCRWDLLGP--LRFVGLSNWRSVL
MSMEG_4466|M.smegmatis_MC2_155      YALVAPSLFGVVTFLLLPMLVVVWLSLHRWDLLGP--IEFVGLDNWTSVL
MAB_1717c|M.abscessus_ATCC_199      YGLLAPSLFGVAAFLLLPILVVVWLSLCRWDLLGP--IEFVGLDNWRSVL
Mflv_3852|M.gilvum_PYR-GCK          LYLTLPSYVVMLLVTAYPLGYALVLSLYNFRLTDPEGRSFVGLGNYLVIL
Mvan_2543|M.vanbaalenii_PYR-1       IYLTLPSYVVMLLVTAYPLGYALVLSLYNFRLTDPEGRSFVGLSNYLVIL
TH_4307|M.thermoresistible__bu      YWLIAPAVLLMVAVTGYPIAYAVWLSLLRYNLAQPDDVSFVGLENYVTVL
                                      *  *: . :  .   *:  .: *** .: *  *    :*** *:  :*

Rv2316|M.tuberculosis_H37Rv         TDSGFADSLVVTAVFVAIVVPAQTVLGLLAASLLARRLPGTGLFRTLYVL
Mb2343|M.bovis_AF2122/97            TDSGFADSLVVTAVFVAIVVPAQTVLGLLAASLLARRLPGTGLFRTLYVL
MMAR_3617|M.marinum_M               RDGDFGNSLVVTAIFVAIVVPAQTVLGLLAAMMLTRRLPGTNFFRTLYVL
MUL_1248|M.ulcerans_Agy99           RDGDFGNSLVVTAIFVAIVVPAQTVLGLLAAMMLTRRLPGTNFFRTLYVL
MLBr_01768|M.leprae_Br4923          TDPNFANSLIVTAVFVAIVVPTQTMLGLLIATMLARQLPGTGVFRTLYVL
MAV_2090|M.avium_104                TDAGFGNSLMVTAVFVAMVVPAQTALGLLAATMLARRLPGTGLFRTVYVL
MSMEG_4466|M.smegmatis_MC2_155      TDPAFGKSLVVTLLFMALVVPTQTVLGLVAATMLARGLPGTGFFRTVYVL
MAB_1717c|M.abscessus_ATCC_199      TDGTFGHSLLVTLLFVALVIPVQTALGLAAATLLVRGLPGTVLFRTIYVI
Mflv_3852|M.gilvum_PYR-GCK          TDPIWWNDFVTTLAITVVTVAIELVLGFWFAFVMLRIVRGRGPLRTAILI
Mvan_2543|M.vanbaalenii_PYR-1       TDPLWWNDFVTTLAITVVTVAIELVLGFWFAFVMLRIVRGRGPLRTAILI
TH_4307|M.thermoresistible__bu      TDEYWWTAFAVTLGITVVSVAIEFVLGLALALVMHRTIFGKGVVRTAILI
                                     *  :   : .*  : .: :. :  **:  * :: * : *   .**  ::

Rv2316|M.tuberculosis_H37Rv         PWICAPLAIAVMWRWIVAPTDGAISTVLG-HRIEWLTDPGLALPVVSAVV
Mb2343|M.bovis_AF2122/97            PWICAPLAIAVMWRWILAPTDGAISTVLG-HRIEWLTDPGLALPVVSAVV
MMAR_3617|M.marinum_M               PWICAPLAIAVMWRWILAPTDGAISTLLG-RRIEWLTDPDLALPVVAAVV
MUL_1248|M.ulcerans_Agy99           PWICAPLAIAVMWRWILAPTDGAISTLLG-RRIEWLTDPDLALPVVAAVV
MLBr_01768|M.leprae_Br4923          PWICAPLAIAVLWRWLLAPTDGAFSMVLR-HRIEWLSDPSLALPVVSAVV
MAV_2090|M.avium_104                PWICAPLAIAVLWRWILAPTDGAVSAVLG-HSIEWLSDPSFALPLVSAVV
MSMEG_4466|M.smegmatis_MC2_155      PWICAPLAIAVLWRWILAPTDGALSTVLG-TRIEWLTDPSLALPVVSAVV
MAB_1717c|M.abscessus_ATCC_199      PWICAPLAIGVLWHWMLAPTDGAVNALLG-QRVEWLTDPSLALPVVAAVS
Mflv_3852|M.gilvum_PYR-GCK          PYGIVTVVSAFIWRYAFAIDSGFVNQWLNLTDFDWFGDRWSAIFVICLSE
Mvan_2543|M.vanbaalenii_PYR-1       PYGIVTVVSAFIWRYAFAIDSGFVNQWLNLTEFDWFGDRWSAIFVICLSE
TH_4307|M.thermoresistible__bu      PYGIVTVAASYSWYYAWTPGTGYLANLLPDGSAPLT-QQLPSLAIVVLAE
                                    *:  ..:. .  * :  :   * .   *         :   :: ::    

Rv2316|M.tuberculosis_H37Rv         VWTNVGYVSLFFLAGLMAIPQDIHNAARTDGASAWQRFWRITLPMLRPTM
Mb2343|M.bovis_AF2122/97            VWTNVGYVSLFFLAGLMAIPQDIHNAARTDGASAWQRFWRITLPMLRPTM
MMAR_3617|M.marinum_M               IWTNVGYVSLSFLAGLLAIPDDIHAAARTDGANAWQRFWRITLPMLRPTT
MUL_1248|M.ulcerans_Agy99           IWTNVGYVSLSFLAGLLAIPDDIHAAARTDGANAWQRFWRITLPMLRPTT
MLBr_01768|M.leprae_Br4923          VWTNVGYVSLSFLAGLLSIPEDINAAARTDGADAWQRFWRITLPMLRPTM
MAV_2090|M.avium_104                VWTNVGYVSLSFLAGLLAIPEDIHAAARTDGANAWQRFWRITMPMLRPTT
MSMEG_4466|M.smegmatis_MC2_155      VWTNVGYVTLFFLAGILNIPADLHNAARTDGADAWQRFRHITLPMLRPTM
MAB_1717c|M.abscessus_ATCC_199      VWTNVGYVALFFMAGLLAIPGDVHNAARVDGATAWQRFRRITLPMLRPTF
Mflv_3852|M.gilvum_PYR-GCK          IWKTTPFISLLLLAGLVQVPEDMQEAAKVDGATAWQRLWKITLPNMKAAI
Mvan_2543|M.vanbaalenii_PYR-1       IWKTTPFISLLLLAGLVQVPEDMQEAAKVDGATAWQRLWKITLPNMKAAI
TH_4307|M.thermoresistible__bu      VWKTTPFMALLLLAGLALVPQELLNAAQMDGANAWQRLVKIILPMIKPAI
                                    :*... :::* ::**:  :* ::  **: *** ****: :* :* ::.: 

Rv2316|M.tuberculosis_H37Rv         FFVLVTGIISAAQVFDTVYALTGGGPQGSTDLVAHRIYAEAFGAAAIGRA
Mb2343|M.bovis_AF2122/97            FFVLVTGIISAAQVFDTVYALTGGGPQGSTDLVAHRIYAEAFGAAAIGRA
MMAR_3617|M.marinum_M               FFVLVTGIVSAAQIFDIVYALTGGGPEGSTELVAHQIYAEAFGSAAIGRA
MUL_1248|M.ulcerans_Agy99           FFVLVTGIVSAAQIFDIVYALTGGGPEGSTELVAHQIYAEAFGSAAIGRA
MLBr_01768|M.leprae_Br4923          FFVLVTGIVSTAQVFDTVYALTDGGPKSRTDLVAHRIYAEAFGSAAIGRA
MAV_2090|M.avium_104                FFVLVTGIVSSAQVFDTVYALTGGGPAGSTDLVAHRIYAEAFGSAAIGRA
MSMEG_4466|M.smegmatis_MC2_155      FFVLVTGIVSAAQVFDTVYALTAGGPQGRTDLIAHRIYAEAFGAAAVGRA
MAB_1717c|M.abscessus_ATCC_199      FFVLVTGVVSAVQTFDTVYALTSGGPQNRTDLAAHRVYAEAFEAAHVGRS
Mflv_3852|M.gilvum_PYR-GCK          MVALLFRTLDAWRIFDNPYVMTAG--ANNTETISFLAYRQNVTLVNLGMG
Mvan_2543|M.vanbaalenii_PYR-1       MVALLFRTLDAWRIFDNPYVMTAG--ANNTETISFLAYRQNVTLVNLGMG
TH_4307|M.thermoresistible__bu      LVALLFRTLDAFRIFDNIYILTGG--ANNTGSVSILGYNNLFKAFNLGLG
                                    :..*:   :.: : **  * :* *   . *   :   * : .    :* .

Rv2316|M.tuberculosis_H37Rv         SVMAVVLFVILVGATVVQHLYFRRRISYELT---
Mb2343|M.bovis_AF2122/97            SVMAVVLFVILVGATVVQHLYFRRRISYELT---
MMAR_3617|M.marinum_M               SVMAVVLFVILIGVTFVQHMYFRRRISYDLT---
MUL_1248|M.ulcerans_Agy99           SVMAVVLFVILIGVTFVQHMYFRRRISYDLT---
MLBr_01768|M.leprae_Br4923          SVMAVLLFVVLFGVTVVQHLYFQRRISYELT---
MAV_2090|M.avium_104                SVMAVVLFVILIGVTLVQHLYFRRRISYDLT---
MSMEG_4466|M.smegmatis_MC2_155      AVMALVLFVLLVGVTIVQHLYFRRRISYELT---
MAB_1717c|M.abscessus_ATCC_199      AAMSLILFLILVTITVIQHRYFRARVSYDLV---
Mflv_3852|M.gilvum_PYR-GCK          SAVSVLLFLSVVAIAWIFIKVFKTDLSQVRGDQ-
Mvan_2543|M.vanbaalenii_PYR-1       SAVSVLLFLSVVGIAWIFIKVFKTDLSQVRGDQ-
TH_4307|M.thermoresistible__bu      SAISVLIFLCVAVIAFIYIKIFGTSAPGSDAERS
                                    :.:::::*: :   : :    *    .