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VSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQAS AFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGL LYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMS GGAGGTGGAAGLLGWGANGGAGGLGDGVGVDRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEP TVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNG IVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALP GDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGS GTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. tuberculosis H37Rv | Rv1983 | PE_PGRS35 | - | 100% (558) | PE-PGRS FAMILY PROTEIN |
M. tuberculosis H37Rv | Rv2591 | PE_PGRS44 | 7e-91 | 61.42% (267) | PE-PGRS family protein |
M. tuberculosis H37Rv | Rv1067c | PE_PGRS19 | 4e-87 | 59.51% (284) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2005 | PE_PGRS35 | 0.0 | 99.82% (558) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 3e-29 | 50.67% (150) | triple helix repeat-containing collagen |
M. leprae Br4923 | MLBr_01183 | - | 7e-14 | 39.42% (104) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_0321c | - | 4e-16 | 31.58% (228) | hypothetical protein MAB_0321c |
M. marinum M | MMAR_2933 | - | 0.0 | 69.71% (558) | PE-PGRS family protein |
M. avium 104 | MAV_1346 | - | 5e-25 | 35.51% (276) | PE family protein |
M. smegmatis MC2 155 | MSMEG_0868 | - | 7e-37 | 40.24% (251) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 1e-16 | 35.24% (227) | PUTATIVE - |
M. ulcerans Agy99 | MUL_4399 | - | 5e-92 | 60.00% (285) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_0928 | - | 8e-38 | 40.78% (255) | carboxymuconolactone decarboxylase |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 --------------------MSGTQSAESDDDADDSEGDASADDAEDAEE MUL_4399|M.ulcerans_Agy99 -------------------------------------------------- Rv1983|M.tuberculosis_H37Rv -------------------------------------------------- Mb2005|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2933|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 FVGDSGNGGSDDDAADDSEKDVDSSTDDGVGDFEGVVLDDAESEADSQLS MUL_4399|M.ulcerans_Agy99 --------MSYLLVAPELLTSAATDLEGIASALSTANLAAAVPTTGMLAA Rv1983|M.tuberculosis_H37Rv -------------------------------------------------- Mb2005|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2933|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 VPQPASTESTEQSADVANDADGNADPIADAGPEAVTAPVALSGASAPAIP MUL_4399|M.ulcerans_Agy99 GADEVSAAVASLFAGYGQAYQSISLQANAFQAQFIQAINGAGGAYVAAEA Rv1983|M.tuberculosis_H37Rv -----------------------MS-FLVVVPEFLTSAAADVENIGSTLR Mb2005|M.bovis_AF2122/97 -----------------------MS-FLVVVPEFLTSAAADVENIGSTLR MMAR_2933|M.marinum_M -----------------------MS-LLVVAPEWLTSAAAELQSIESALS MLBr_01183|M.leprae_Br4923 -----------------------MPLFLNAEPQALTAAANTLEGLSAATV MAV_1346|M.avium_104 -----------------------MS-FVTTRPEALLAVASMLEGLGSSMD Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 DGP-----------------------------------APVEPMGPLINS MUL_4399|M.ulcerans_Agy99 AS--------------------------------------TSPLQAFEDT Rv1983|M.tuberculosis_H37Rv AAN----------------------------------------------- Mb2005|M.bovis_AF2122/97 AAN----------------------------------------------- MMAR_2933|M.marinum_M AAN----------------------------------------------- MLBr_01183|M.leprae_Br4923 ASN----------------------------------------------- MAV_1346|M.avium_104 AQN----------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 LWWAVPKSGGRSTNDASLTLAGTGIYPSVTSLFAFGGRCGLICDGADGTE MUL_4399|M.ulcerans_Agy99 VLG------------------------VINAPTQTLLGRPLIGDGAAGTV Rv1983|M.tuberculosis_H37Rv ------------------------------------AAAAASTTALAAAG Mb2005|M.bovis_AF2122/97 ------------------------------------AAAAASTTALAAAG MMAR_2933|M.marinum_M ------------------------------------AAAAVPTTGLAAAA MLBr_01183|M.leprae_Br4923 ------------------------------------AAAAQLTTEIAPPA MAV_1346|M.avium_104 ------------------------------------AAAAAPTTSIAPAA Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFS------------ MAB_0321c|M.abscessus_ATCC_199 ------------------------------MAN----------------- Mvan_0928|M.vanbaalenii_PYR-1 QNPNGVGGGWLFGDGGDGWSSTLAGIAGGKGGAAG--------------- MUL_4399|M.ulcerans_Agy99 ANPNGGAGGFLYGNGGNGFSQTTAGVAGGAGGAAG--------------- Rv1983|M.tuberculosis_H37Rv ADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQT-------------- Mb2005|M.bovis_AF2122/97 ADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQT-------------- MMAR_2933|M.marinum_M ADEVSTAVATLFAGFGQEYQAISTQLSAFQQQFALT-------------- MLBr_01183|M.leprae_Br4923 ADDVSILLAHFFSGHGRQYQAHASQGATNHQDLIQS-------------- MAV_1346|M.avium_104 ADEVSALQAAQFSAYGTWYQQVSAQAKAIHQTLVQN-------------- Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG TH_3810|M.thermoresistible__bu -------------KLSRGGDGGDGGLG-------------GNGGHGGGTG MAB_0321c|M.abscessus_ATCC_199 -------------IISNGPDGDAGATG--------------AQGSQGAT- Mvan_0928|M.vanbaalenii_PYR-1 ------------LLWGSGGDGGAGGAG-------------AAGGTGGNAG MUL_4399|M.ulcerans_Agy99 -------------LIGNGGMGGAGGAG-------------AAGGAGGTGG Rv1983|M.tuberculosis_H37Rv -------------LNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETL Mb2005|M.bovis_AF2122/97 -------------LNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETL MMAR_2933|M.marinum_M -------------LNSSAGSYSAAEAQSVSILDTLGQDVFGAINAPTEAL MLBr_01183|M.leprae_Br4923 -------------LLTSSSAYAGTETAN---------------------- MAV_1346|M.avium_104 -------------LDTNADSYGATEAANRVNTSAAALQGLAPNVIPNAAP . Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT TH_3810|M.thermoresistible__bu IIS--------------------LLSLAGNGGNGG--------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------GAAGAMANCN--------------- Mvan_0928|M.vanbaalenii_PYR-1 LLWG-----------------NGGHGGAGGAGVNG--------------- MUL_4399|M.ulcerans_Agy99 WWFG-----------------NGGVGGAGGAGTAG--------------- Rv1983|M.tuberculosis_H37Rv LGRP----------------------LIGDGAPG---------------- Mb2005|M.bovis_AF2122/97 LGRP----------------------LIGDGAPG---------------- MMAR_2933|M.marinum_M LGRP----------------------LIGNGANG---------------- MLBr_01183|M.leprae_Br4923 ------------------------------HDSL---------------- MAV_1346|M.avium_104 AADP----------------------PPAGTTSLG--------------- Mflv_5091|M.gilvum_PYR-GCK VG--SAGAAGEAGETGTWGNAGLPGKAGDAGGAG----AVGAAG---AAG MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH TH_3810|M.thermoresistible__bu ------------------------------------------NG----YR MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------W Mvan_0928|M.vanbaalenii_PYR-1 -----------------------------------------------AVG MUL_4399|M.ulcerans_Agy99 -----------------------------------------------AVG Rv1983|M.tuberculosis_H37Rv -------------------------------------------------- Mb2005|M.bovis_AF2122/97 -------------------------------------------------- MMAR_2933|M.marinum_M -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------T Mflv_5091|M.gilvum_PYR-GCK TVGTAGATGGTG----TGANGGAGGVG-----GVGGTGAAGAAGGAG--- MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS TH_3810|M.thermoresistible__bu TTDNNALDGGHG------GNGGN--------------------------- MAB_0321c|M.abscessus_ATCC_199 IDDDCATRGGTG-------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 TSGVNNGRGGDGTAGGSGGAGGNAGLLS---------------------- MUL_4399|M.ulcerans_Agy99 FNGVSGGAGGAG-------------------------------------- Rv1983|M.tuberculosis_H37Rv -TATSPNGGAGG-------------------------------------- Mb2005|M.bovis_AF2122/97 -TATSPNGGAGG-------------------------------------- MMAR_2933|M.marinum_M -TATSPNGGAGG-------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 SIGWAQNVGAAA-------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---GLGETGTTG--------------GAGGVGGQGTAGGTGGVGGIG--- MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY TH_3810|M.thermoresistible__bu --VGFFSLFNLG--------------GAGGWGGSGVDG------------ MAB_0321c|M.abscessus_ATCC_199 --------------------------GTGGNGGP---------------- Mvan_0928|M.vanbaalenii_PYR-1 ---GRGGDGGVG--------------GAGGKGGAGAHG------------ MUL_4399|M.ulcerans_Agy99 ---GAAGWWGAG--------------GAGGQGGTG--------------- Rv1983|M.tuberculosis_H37Rv -----------------------LLYGNGGNGYSATASG----------- Mb2005|M.bovis_AF2122/97 -----------------------LLYGNGGNGYSATASG----------- MMAR_2933|M.marinum_M -----------------------LLFGNGGIGYSQTGAG----------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -----------------------SDFITLGEGQFAPVPG----------- Mflv_5091|M.gilvum_PYR-GCK --------------------GAGSTGAVGG-----------VGGKGIQGG MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA TH_3810|M.thermoresistible__bu ------------------------VDVVGG-------------------- MAB_0321c|M.abscessus_ATCC_199 ----------------------------GG-------------------- Mvan_0928|M.vanbaalenii_PYR-1 ------------------------SDAVAAE------------------- MUL_4399|M.ulcerans_Agy99 -------------------------GMAGG-------------------- Rv1983|M.tuberculosis_H37Rv ------------------------VGG----------------------- Mb2005|M.bovis_AF2122/97 ------------------------VGG----------------------- MMAR_2933|M.marinum_M ------------------------IVG----------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ------------------------AAG----------------------- Mflv_5091|M.gilvum_PYR-GCK QGLQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV TH_3810|M.thermoresistible__bu -------NPDGGTPG------------------------------AHGES MAB_0321c|M.abscessus_ATCC_199 ---------AGGPGG-------------------------------HGGV Mvan_0928|M.vanbaalenii_PYR-1 --------EDGGPGG-------------------------------SGGA MUL_4399|M.ulcerans_Agy99 ---------YDNVNG------------------------------VFGIT Rv1983|M.tuberculosis_H37Rv --------GAGGSAG----------------------------LIGNGGA Mb2005|M.bovis_AF2122/97 --------GAGGSAG----------------------------LIGNGGA MMAR_2933|M.marinum_M --------GAGGSAG----------------------------LIGNGGA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 --------IPNFNPG----------------------------LTAATTA Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNG------------- MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP TH_3810|M.thermoresistible__bu HTPGVYTDRQ---------------------------------------- MAB_0321c|M.abscessus_ATCC_199 IDFEVETFMD---------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 GGNAG--------------------------------------------- MUL_4399|M.ulcerans_Agy99 AGNGG--------------------------------------------- Rv1983|M.tuberculosis_H37Rv GGAGGPNAPG---------------------------------------- Mb2005|M.bovis_AF2122/97 GGAGGPNAPG---------------------------------------- MMAR_2933|M.marinum_M GGTGGAGATG---------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 GPPAPAAPAA---------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ---------ADGGTGGAGGAGGTGG-TGGAGGTGG--------------- MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ TH_3810|M.thermoresistible__bu ---------------GEDGEDGTGTGIGGRGGNGG--------------- MAB_0321c|M.abscessus_ATCC_199 --------------------GVTLQAKGGRGGNGG--------------- Mvan_0928|M.vanbaalenii_PYR-1 ----------------AGGVGGRGALLFGRGGDGG--------------- MUL_4399|M.ulcerans_Agy99 ----------------DGGAGGRGGWLFGDAGAGG--------------- Rv1983|M.tuberculosis_H37Rv ------------------GAGGNGGWLLGNGGIGG--------------- Mb2005|M.bovis_AF2122/97 ------------------GAGGNGGWLLGNGGIGG--------------- MMAR_2933|M.marinum_M ------------------GAGGNGGWLFGSGGIGG--------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ------------------AAG--APVLASMGRGPS--------------- Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG TH_3810|M.thermoresistible__bu -SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGGHG MAB_0321c|M.abscessus_ATCC_199 ------------------------------------HGGAGGTGGTGGKG Mvan_0928|M.vanbaalenii_PYR-1 --DGGSAGTGGAGGFGGTGGAIVVTLPGGKLSDSDGAGGAGGVGGAAGLG MUL_4399|M.ulcerans_Agy99 -----QGGLGGDGNYAGQGSYGGVGGAGGAGG----AAGMFGSGGSGGAG Rv1983|M.tuberculosis_H37Rv --------------------------PGGASSIPGMSGGAGGTGGAAGLL Mb2005|M.bovis_AF2122/97 --------------------------PGGASSIPGMSGGAGGTGGATGLL MMAR_2933|M.marinum_M --------------------------TGGANALG--TGGTGGLGGSAGLF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 --------------------------IGGLSVPPSWAPGGVAPAANATPA Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG TH_3810|M.thermoresistible__bu GRGGFLGIGGSG-------GWGGHGGNGGD-----------TDADGGNGG MAB_0321c|M.abscessus_ATCC_199 GDGDDCEFGRTG-------GNGGTGGRGGD------------GNFAGTGG Mvan_0928|M.vanbaalenii_PYR-1 GDGGGGGLGGLLG------QAGVNGDSGAT---------AAAGNAGGVGG MUL_4399|M.ulcerans_Agy99 GEGGAFGDGNAGG-----SGSGGHGGNGGNG-----------GWLYGDAG Rv1983|M.tuberculosis_H37Rv GWGANGGAGGLGDGVGVDRGTGGAGGRGGLL-----------YGGYGVSG Mb2005|M.bovis_AF2122/97 GWGANGGAGGLGDGVGVDRGTGGAGGRGGLL-----------YGGYGVSG MMAR_2933|M.marinum_M GGGGNGGAGGLG--ISGDLGTGGAGGTGGFL-----------LGDYGVSG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 QLVGAGFTSAAPDTAPVTAVPGGVPSMATAG-----------RGGYGLGA Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------- MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG TH_3810|M.thermoresistible__bu DG---------------GNGGSAG-------------------------- MAB_0321c|M.abscessus_ATCC_199 NG------------------------------------------------ Mvan_0928|M.vanbaalenii_PYR-1 AG---------------GLGGRLPIVDLNNASPAQATLAALIKKLGLPIQ MUL_4399|M.ulcerans_Agy99 AG---------------GQGGNAAP------------------------- Rv1983|M.tuberculosis_H37Rv PG------------------------------------------------ Mb2005|M.bovis_AF2122/97 PG------------------------------------------------ MMAR_2933|M.marinum_M AG------------------------------------------------ MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 PR------------------------------------------------ Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH TH_3810|M.thermoresistible__bu -------RGGTGGLRGVFGINGGNG------------------------R MAB_0321c|M.abscessus_ATCC_199 -----------GAILVKCQHDLSLG------------------------T Mvan_0928|M.vanbaalenii_PYR-1 AATGIQLEDVDGRLVGPLNAYLYNTIIGKAIFDVGNTFSSASLSARVKEI MUL_4399|M.ulcerans_Agy99 --------GAYSDNLGTFQSSYTSG------------------------N Rv1983|M.tuberculosis_H37Rv ----------GDGRTVPLEIIHVTEP-----------------------T Mb2005|M.bovis_AF2122/97 ----------GDGRTVPLEIIHVTEP-----------------------T MMAR_2933|M.marinum_M ----------GDGRTVPLEVVNVTEP-----------------------V MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 ----------YGVKPTVMPKPAI--------------------------- Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD TH_3810|M.thermoresistible__bu AGLGGRGXXXXGGGVG---------------AAVRSGNGVFSGGGGTPSA MAB_0321c|M.abscessus_ATCC_199 HPMDVSAGTGGNGGIG----------------GGGGGGGSVGANG--ATT Mvan_0928|M.vanbaalenii_PYR-1 VILSVGGQWGSEYELYAHKLAAQLFG-----IPADAIAALANGQAPVGLS MUL_4399|M.ulcerans_Agy99 GGAGGNGGVAGMIGTGG--------------AGGAGGAGGVNAFDSGGGG Rv1983|M.tuberculosis_H37Rv VHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYS Mb2005|M.bovis_AF2122/97 VHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYS MMAR_2933|M.marinum_M VNVNVNGGHSTPVLIDTGSAGLVMQVKDVGGPLGLLRMGLPSGISMSAYS MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGKA MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGSTL TH_3810|M.thermoresistible__bu GFGVPTTIQFPAGSCTSRAVSREG------------------------IM MAB_0321c|M.abscessus_ATCC_199 GVFSSSSDCSGPGPQPNPGSPGDP-------------------------- Mvan_0928|M.vanbaalenii_PYR-1 GNELLAAQFVQELVSTRRVSDALFEAAEAAFGQTGVVDMVNLAGTYLGVS MUL_4399|M.ulcerans_Agy99 G-GGGNGGNGGAGGASGALIEAGG----------------------VGGS Rv1983|M.tuberculosis_H37Rv GGLYYIFATYTTTVDFGNGIVTAP------------------TAVNVVLL Mb2005|M.bovis_AF2122/97 GGLYYIFATYTTTVDFGNGIVTAP------------------TAVNVVLL MMAR_2933|M.marinum_M GGLTYLFATYPTTVDFGNGIVTST------------------TGVDVVLF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGATG MSMEG_0868|M.smegmatis_MC2_155 GGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDGG TH_3810|M.thermoresistible__bu PSSRAASARAG---------------------------AACASSTSRSRR MAB_0321c|M.abscessus_ATCC_199 ---GTSVAVSG------------------------------AQGNPGQAQ Mvan_0928|M.vanbaalenii_PYR-1 ATLNAFKVRGPESFSAPVLPAAPSPVPASDEYGLGGRLPLIDLDTATPAQ MUL_4399|M.ulcerans_Agy99 GGGGGAGVVGP------------------------------PAGNPGNDG Rv1983|M.tuberculosis_H37Rv SIPTSPFAISTYFS-----------------------ALLADPTTTPFEA Mb2005|M.bovis_AF2122/97 SIPTSPFAISTYFS-----------------------ALLADPTTTPFEA MMAR_2933|M.marinum_M SIPTSPYALTTWLN-----------------------ALWSNPLTTPFDA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGKA MSMEG_0868|M.smegmatis_MC2_155 AATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGWV TH_3810|M.thermoresistible__bu SFCCSRA------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 FLIVP--------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 LDLAAKIKALAVPTQQATGIELVSPDGRLIGPLNGYLYNPVIGQALFEVG MUL_4399|M.ulcerans_Agy99 LDGVTGASGLLFGG------------------------------------ Rv1983|M.tuberculosis_H37Rv YFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGP Mb2005|M.bovis_AF2122/97 YFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGP MMAR_2933|M.marinum_M YFQSAGVDGVLGVGPNAVGPGPSIPTQALGGGLGQGLLIDMKGGELVFGP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GATG-TTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------ MSMEG_0868|M.smegmatis_MC2_155 QAYD-PAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 NAFASSSLSSRIKEIVILSVGGQWGSGYEVYAHEKVARLVGIPEEAIVSL MUL_4399|M.ulcerans_Agy99 -------------------------------------------------- Rv1983|M.tuberculosis_H37Rv NPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGS Mb2005|M.bovis_AF2122/97 NPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGS MMAR_2933|M.marinum_M NPL-TPEFSISGAPIATLWVSVNGGAPVAVPSIIDSGGVMGTIPSSVIGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -----------AGGEGGEGGDGGKGGAG--AEGGAGGGGGAGGSGAGGAG MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- Mvan_0928|M.vanbaalenii_PYR-1 ASGHAPVGLSGSELVAARFVQELVSTYEVSSELYHSAEAAFGQAGLVDLV MUL_4399|M.ulcerans_Agy99 -------------------------------------------------- Rv1983|M.tuberculosis_H37Rv GTLPANTNIEVYTS-PGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQP Mb2005|M.bovis_AF2122/97 GTLPANTNIEVYTS-PGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQP MMAR_2933|M.marinum_M STLPANTNITVYTDNTMTTEVYHYSTNDYQPTVISSGLMNTGFLPFWNQP MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAV_1346|M.avium_104 -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD- MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP- TH_3810|M.thermoresistible__bu ----------------------------- MAB_0321c|M.abscessus_ATCC_199 ----------------------------- Mvan_0928|M.vanbaalenii_PYR-1 NLASTYLGASALLNVFEVPVPTAALITTS MUL_4399|M.ulcerans_Agy99 ----------------------------- Rv1983|M.tuberculosis_H37Rv VYIDYSPSGIGTTVFDHPA---------- Mb2005|M.bovis_AF2122/97 VYIDYSPSGIGTTVFDHPA---------- MMAR_2933|M.marinum_M VYIDYSPAGTGTTVFDMP----------- MLBr_01183|M.leprae_Br4923 ----------------------------- MAV_1346|M.avium_104 -----------------------------