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MSSTVVDSPAGCTQSERLEVLFEELSELAGQRNAIDGRIVEIAAQIDRDGLVGITGARSVAALVAWKTGC SPHNAKTITTVADRLEEFPRCVTALGEGRLSLDQVAVIAEHAGQGSDAHYAHLAASASVSQLRTAVKSEP RPDPEPVRDPFADADEEPEPAPVPRPEITSTCDADYTYWRIKLPHEQSARFTAALQSHKDRLIAQHTRDH GTDPTGDGDGDRGVQLPPWPSAGEAFMELVEAGWDAEATRRPHGQHTTVVVHVDIDTRVAALHLGPLLTD EERRFLLCDATCEVWFQRHGRPLGTGRSTRTINRRLRRALEHRDRTCVVPGCGATRGLHAHHLVHWEDGG DTELDNLVLVCPYHHRTHHRGLITITGPAHQLLVTDHTGRPLQPGSLARPPTTPPPEVNPYPGTSGERAQ WKWYHPYQPPPPTSNN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0040 | - | - | 100% (436) | hypothetical protein Mvan_0040 |
| M. vanbaalenii PYR-1 | Mvan_4621 | - | e-166 | 61.59% (479) | hypothetical protein Mvan_4621 |
| M. vanbaalenii PYR-1 | Mvan_2373 | - | e-165 | 62.28% (464) | hypothetical protein Mvan_2373 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1794c | - | 1e-167 | 66.97% (436) | hypothetical protein Mb1794c |
| M. gilvum PYR-GCK | Mflv_1988 | - | 0.0 | 73.00% (426) | hypothetical protein Mflv_1988 |
| M. tuberculosis H37Rv | Rv2015c | - | 1e-167 | 66.97% (436) | hypothetical protein Rv2015c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 1e-10 | 41.25% (80) | hypothetical protein MAB_0394c |
| M. marinum M | MMAR_0868 | - | 6e-09 | 37.21% (86) | hypothetical protein MMAR_0868 |
| M. avium 104 | MAV_0036 | - | 1e-158 | 63.07% (436) | hypothetical protein MAV_0036 |
| M. smegmatis MC2 155 | MSMEG_3404 | - | 1e-152 | 62.84% (436) | HNH endonuclease domain-containing protein |
| M. thermoresistible (build 8) | TH_1926 | - | 3e-40 | 68.27% (104) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1813 | - | 6e-05 | 30.43% (138) | 13e12 repeat-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0394c|M.abscessus_ATCC_199 MSPIDDLLTTATAVVESS----FDELNNPELLSALRQLEIAQRKITAASH
MMAR_0868|M.marinum_M MRSIAGLLDALDAAVAAIGEAHLEGLQPVERLRMLARLETARRLQAVISH
Mb1794c|M.bovis_AF2122/97 ---------MSS-TATSGAAVVSPAERVEVLFEELAELAGQRNAIDGRIV
Rv2015c|M.tuberculosis_H37Rv ---------MSS-TATSGAAVVSPAERVEVLFEELAELAGQRNAIDGRIV
MAV_0036|M.avium_104 ---------MSS-SVLAAEVEVRPYDRLAVLFDELAELTGQRNAIDGRIV
Mvan_0040|M.vanbaalenii_PYR-1 ---------MSSTVVDSPAGCTQSE-RLEVLFEELSELAGQRNAIDGRIV
Mflv_1988|M.gilvum_PYR-GCK ---------MRPGSAPSFIPSPPREARLEALFDELSELAGQRNAIDGRIV
MSMEG_3404|M.smegmatis_MC2_155 ---------MTS-AATSPAAQPTPVERLEALFDALAELTGQRNAIDAKIV
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 -----------------------MERAREASRREAAAAAERLDVVGALFV
MAB_0394c|M.abscessus_ATCC_199 TLTARLVQRGSPVALGGTSFAEVLARYLSITTATARRRLADAAHLGPRRA
MMAR_0868|M.marinum_M DVIAGLYTED-PAAIGG-PVTKVVADWLRITPTDARRRLRDAQQLSARTT
Mb1794c|M.bovis_AF2122/97 EIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVARRLP----
Rv2015c|M.tuberculosis_H37Rv EIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVARRLP----
MAV_0036|M.avium_104 EIVAQIEREQLWGATGARSLGALVAWKTGCSPGNAETIATVARRLD----
Mvan_0040|M.vanbaalenii_PYR-1 EIAAQIDRDGLVGITGARSVAALVAWKTGCSPHNAKTITTVADRLE----
Mflv_1988|M.gilvum_PYR-GCK DIVAEIDGDQLWGATGARSIAALVAWKLGTSAGNAERIVAIADRAA----
MSMEG_3404|M.smegmatis_MC2_155 QIVAEIDRDGLWGATGARSISALVAWKTGASERNAKAIAAVAHRAE----
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 LRCRESGDRAEWATDTWEAVGAQVAAALRTSVAMGSSYLRYAMAMRN---
MAB_0394c|M.abscessus_ATCC_199 LTGEPLRPALPYVAHALREGRLGDEHVRIIRRFFDVLPDAVDADTREAAE
MMAR_0868|M.marinum_M LTGQVLPPELPATARAWRDGQLDGQHLRVIATFVRDLPQDTAPQIVAGAE
Mb1794c|M.bovis_AF2122/97 --------EFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHYAQLAGVAT
Rv2015c|M.tuberculosis_H37Rv --------EFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHYAQLAGVAT
MAV_0036|M.avium_104 --------SFPRCAAGLREGRFSLDQLGVIAQRAGEGSDEHYAQLAGVAT
Mvan_0040|M.vanbaalenii_PYR-1 --------EFPRCVTALGEGRLSLDQVAVIAEHAGQGSDAHYAHLAASAS
Mflv_1988|M.gilvum_PYR-GCK --------EFPRCTQALREGRLSVDQVGVIAEGAGQGSDDHYARLAQNAS
MSMEG_3404|M.smegmatis_MC2_155 --------EFPRCVQGLGAGRLSLDQVGVIAEGAADGSDEHYAALASVAT
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 --------RLPKVGQAFRAEDIDYRAFQTIVFRTDLITDAEVLAKVDAQL
MAB_0394c|M.abscessus_ATCC_199 KQLASMGTEFGPEQLRAGADRIAALVNPD-GRFSDIDRARRRGISIGRQG
MMAR_0868|M.marinum_M KLLAHQALQLRPDQLEKAAHRCALLINPD-GRFSDADRARQRGFTWCAQR
Mb1794c|M.bovis_AF2122/97 VNQLRTALKLEPRPEPEPDFRPE------------------PRPSITRSA
Rv2015c|M.tuberculosis_H37Rv VNQLRTALKLEPRPEPEPDFRPE------------------PRPSITRSA
MAV_0036|M.avium_104 VNQLRTAVKLEPRPQPE--AKPA------------------PQPGLTKTS
Mvan_0040|M.vanbaalenii_PYR-1 VSQLRTAVKSEPRPDPEPVRDPFADAD------EEPEPAPVPRPEITSTC
Mflv_1988|M.gilvum_PYR-GCK VSQLRTAIKQEPRPEPEPSADDGDEPDHDLPDHDEPEPPSLPTAEITTSC
MSMEG_3404|M.smegmatis_MC2_155 VSQLRKAISLEPKPEPEPKPD--------------------PRRSIRTNP
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 AALLARCPAVTRGRLSVAVDQVVADVDRD------------VVRRVAEAA
MAB_0394c|M.abscessus_ATCC_199 ADGMSALSGLLDPETRAYFDAVLSKLAAPGMCDPRDESPMTEGEPDSAAA
MMAR_0868|M.marinum_M RDGMSIGKLIATPELRANLDAWLARFAAPGMCNPDNQTPCVTDEPTEDAA
Mb1794c|M.bovis_AF2122/97 DEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHD-------NSDG
Rv2015c|M.tuberculosis_H37Rv DEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHD-------NSDG
MAV_0036|M.avium_104 DEELSCWRITLDRLDAATFDAALAAHREALIAEWKRDHN-------HRAG
Mvan_0040|M.vanbaalenii_PYR-1 DADYTYWRIKLPHEQSARFTAALQSHKDRLIAQHTRDHGTDP-TGDGDGD
Mflv_1988|M.gilvum_PYR-GCK DADYTYWRIKLPHEQAATFQAALHSHKDALIAQWTREH--------ADSD
MSMEG_3404|M.smegmatis_MC2_155 GDGYTTYHITLPRLEAAKFDTALEASHEGLIARWEREQ-----------D
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 DGRFVDVDVIADGSGLAALAGSVLATAGRAFDRRLDELANTVCAADPRTR
MAB_0394c|M.abscessus_ATCC_199 ERDTRTSAQRNHDGLRACLRSTLASGKLGAHRGLPVTVVVSTTLRELQSA
MMAR_0868|M.marinum_M ATDARRPAQRQHDALNALVRGQLGDPALGTHNGLPVTVIVSTTLQEITAA
Mb1794c|M.bovis_AF2122/97 VSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAG
Rv2015c|M.tuberculosis_H37Rv VSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAG
MAV_0036|M.avium_104 ES--VPPLPGTLEAFIRLIETGWDAEAHRRPHGHHTTVVVHLDAAQRVAG
Mvan_0040|M.vanbaalenii_PYR-1 RGVQLPPWPSAGEAFMELVEAGWDAEATRRPHGQHTTVVVHVDIDTRVAA
Mflv_1988|M.gilvum_PYR-GCK EGPHRPPLPNLAEAFLALVEASWDAEALRRPHGQHTTVVVHVDVESKLAA
MSMEG_3404|M.smegmatis_MC2_155 PGDPAVPMPDLVDAFMALVETGWDREATRRPHGQHTAVAVHVDLKSKVAA
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 EQRRADAVGALVAGSDRLACGCTSADCTAAARSAPSKVVIHVVADQSTVD
MAB_0394c|M.abscessus_ATCC_199 AGRAISGSGNLVPIPDLIRMATHAFHYLTIFGDDG-RPLHLGRSKRIATP
MMAR_0868|M.marinum_M TGRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSNRPLYLGRTRRIASP
Mb1794c|M.bovis_AF2122/97 LHLGP-------LLSESERRYLLCDATFEAWFERDGQVIGCGRTTRQINR
Rv2015c|M.tuberculosis_H37Rv LHLGP-------LLSESERRYLLCDATFEAWFERDGQVIGCGRTTRQINR
MAV_0036|M.avium_104 LHLGP-------LLSDAERRYLTCDATCEVWVERDGQPIGAGRSTRVINR
Mvan_0040|M.vanbaalenii_PYR-1 LHLGP-------LLTDEERRFLLCDATCEVWFQRHGRPLGTGRSTRTINR
Mflv_1988|M.gilvum_PYR-GCK LHLGP-------LLTAEERRYLSCEATCEVWFERHGRPIGAGRSTRTVNR
MSMEG_3404|M.smegmatis_MC2_155 LHLGP-------LLGDDERRLLTCDATCEVWFELRGRVIGTGRATRTVNR
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 GTGHTP--AVLLGAEGLIPASLIAELAKVATLRPLMRPSGRPESGYAPSA
MAB_0394c|M.abscessus_ATCC_199 DQRIVLHAKDRGCSAPGCTVPGYLCQVHHVDDWRDDGPTDIDNLTFACGP
MMAR_0868|M.marinum_M DQRVVLYAAERGCTHPGCDAPGYWCEVHHLADWAAGGPTDVDNLTFACTP
Mb1794c|M.bovis_AF2122/97 RLRRALEHRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATELANLVLVCPY
Rv2015c|M.tuberculosis_H37Rv RLRRALEHRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATELANLVLVCPY
MAV_0036|M.avium_104 RLRRALEHRHRGCAIPGCGAT-RGLHAHHLRHWEDGGPTELSNLVLVCPY
Mvan_0040|M.vanbaalenii_PYR-1 RLRRALEHRDRTCVVPGCGAT-RGLHAHHLVHWEDGGDTELDNLVLVCPY
Mflv_1988|M.gilvum_PYR-GCK RLRRALEHRDRSCVVPGCGAT-RGLHAHHIVHWEDGGDTELDNLVLVCPY
MSMEG_3404|M.smegmatis_MC2_155 RLRRALEHRDRCCVVPGCSAT-RGLHAHHLVHWEDGGLTEMANLVLLCPY
TH_1926|M.thermoresistible__bu --------------VPGCGAT-RGLHAHHIRHWEHRGPTDLDNLVLVCRY
MUL_1813|M.ulcerans_Agy99 GLAEFVRCRDLTCRARGCDQPAVCCDLDHTVAYGDGGHTHASNLKCLCRK
** . . .* : * *. ** *
MAB_0394c|M.abscessus_ATCC_199 HHRLL-QQGWTTRKRRSDGITEWIPPPHLDTGQSRTNDHHH----PERFI
MMAR_0868|M.marinum_M HHRLA-GKSWQTIKLP-NSRTAWLPPPQLRRG-ARTNDYHH----PERLL
Mb1794c|M.bovis_AF2122/97 HHRAH-HRGLITITGPADNLTVADSAGRPLSAGSLARASTK----PPPAV
Rv2015c|M.tuberculosis_H37Rv HHRAH-HRGLITITGPADNLTVADSAGRPLSAGSLARASTK----PPPAV
MAV_0036|M.avium_104 HHRAH-HRGEITITGPADTLLVTDSSGRHLKPGSLARKPTR----PPPAV
Mvan_0040|M.vanbaalenii_PYR-1 HHRTH-HRGLITITGPAHQLLVTDHTGRPLQPGSLARPPTT----PPPEV
Mflv_1988|M.gilvum_PYR-GCK HHRAH-HRGIIVITGPAHQLAVTDHTGRPLQSGTLARPPTQ----PPPAV
MSMEG_3404|M.smegmatis_MC2_155 HHRAH-HRGLITITGPADQLTVTDDRGRLLTNQSLARTPTT----PPPTV
TH_1926|M.thermoresistible__bu HHRLH-HRGLITISDTPDNLTVSDRDGDRLHPGSLARPPDR----PPPQV
MUL_1813|M.ulcerans_Agy99 HHLLKTFWGWRDLQLPDGTVIWLLPDGHTYVTTPGSALLFPNLCVPTGEL
** . . : * :
MAB_0394c|M.abscessus_ATCC_199 RRF-----------------------------------------------
MMAR_0868|M.marinum_M DDRAAPD-------------------------------------------
Mb1794c|M.bovis_AF2122/97 APWPGPTGERADWWWYEPFQPQPPPISN----------------------
Rv2015c|M.tuberculosis_H37Rv APWPGPTGERADWWWYEPFQPQPPPISN----------------------
MAV_0036|M.avium_104 PPCPGPLGQRADWWWYDPFQPQPPPTTN----------------------
Mvan_0040|M.vanbaalenii_PYR-1 NPYPGTSGERAQWKWYHPYQPPPPTSNN----------------------
Mflv_1988|M.gilvum_PYR-GCK PPYRGPSGERLYWKWYHPYQPPPTATAN----------------------
MSMEG_3404|M.smegmatis_MC2_155 PPCPGPLGERAQWWWYQPFEPQPPPSAN----------------------
TH_1926|M.thermoresistible__bu APCTGPTGERADWWWYTPYQPPAPPPADETGPG-----------------
MUL_1813|M.ulcerans_Agy99 PPIVGTAGKPPRWPSGEDADPCPNPRTKPGESHRHRAPMQSQGTGSRRRR
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0868|M.marinum_M --------------------------------------------------
Mb1794c|M.bovis_AF2122/97 --------------------------------------------------
Rv2015c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0036|M.avium_104 --------------------------------------------------
Mvan_0040|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1988|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3404|M.smegmatis_MC2_155 --------------------------------------------------
TH_1926|M.thermoresistible__bu --------------------------------------------------
MUL_1813|M.ulcerans_Agy99 PRRPVRHPGAGNRSRRAAALLAATSLGTCQIPRRIAPRPGPSRSSRGCTD
MAB_0394c|M.abscessus_ATCC_199 --------------------
MMAR_0868|M.marinum_M --------------------
Mb1794c|M.bovis_AF2122/97 --------------------
Rv2015c|M.tuberculosis_H37Rv --------------------
MAV_0036|M.avium_104 --------------------
Mvan_0040|M.vanbaalenii_PYR-1 --------------------
Mflv_1988|M.gilvum_PYR-GCK --------------------
MSMEG_3404|M.smegmatis_MC2_155 --------------------
TH_1926|M.thermoresistible__bu --------------------
MUL_1813|M.ulcerans_Agy99 SGTRMGESSMSARPRACVAG