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SSTATSGAAVVSPAERVEVLFEELAELAGQRNAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCS SGNAHTIATVARRLPEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHYAQLAGVATVNQLRTALKLEPR PEPEPDFRPEPRPSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDHDNSDGVSDQRPPL PGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMHLDVQERAAGLHLGPLLSESERRYLLCDATFEAWFERD GQVIGCGRTTRQINRRLRRALEHRDRTCVVPGCGATRGLHAHHIRHWQDGGATELANLVLVCPYHHRAHH RGLNRPGESGDSLI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1765c | - | - | 100% (365) | hypothetical protein Rv1765c |
| M. tuberculosis H37Rv | Rv2015c | - | 0.0 | 100.00% (354) | hypothetical protein Rv2015c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1794c | - | 0.0 | 100.00% (354) | hypothetical protein Mb1794c |
| M. gilvum PYR-GCK | Mflv_1988 | - | 1e-135 | 66.29% (356) | hypothetical protein Mflv_1988 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0990c | - | 6e-09 | 33.88% (121) | hypothetical protein MAB_0990c |
| M. marinum M | MMAR_0868 | - | 3e-08 | 25.24% (313) | hypothetical protein MMAR_0868 |
| M. avium 104 | MAV_4292 | - | 1e-151 | 76.42% (335) | hypothetical protein MAV_4292 |
| M. smegmatis MC2 155 | MSMEG_3404 | - | 1e-131 | 63.28% (354) | HNH endonuclease domain-containing protein |
| M. thermoresistible (build 8) | TH_1926 | - | 8e-19 | 70.37% (54) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2371 | - | 6e-05 | 33.06% (121) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_0040 | - | 1e-142 | 67.20% (372) | hypothetical protein Mvan_0040 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1765c|M.tuberculosis_H37Rv ------------------MSSTATSGAAVVSPAERVEVLFEELAELAGQR
Mb1794c|M.bovis_AF2122/97 ------------------MSSTATSGAAVVSPAERVEVLFEELAELAGQR
MAV_4292|M.avium_104 -------------------------------------MLFEELAELTGQR
Mflv_1988|M.gilvum_PYR-GCK -----------------MRPGSAPSFIPSPPREARLEALFDELSELAGQR
Mvan_0040|M.vanbaalenii_PYR-1 -----------------MSSTVVDSPAGCTQSE-RLEVLFEELSELAGQR
MSMEG_3404|M.smegmatis_MC2_155 ------------------MTSAATSPAAQPTPVERLEALFDALAELTGQR
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 ------------MSSIGVVEAAVDAFCAESIEDLTAGEALAMLARLKVVQ
MUL_2371|M.ulcerans_Agy99 MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLEVVA
MMAR_0868|M.marinum_M --------MRSIAGLLDALDAAVAAIGEAHLEGLQPVERLRMLARLETAR
Rv1765c|M.tuberculosis_H37Rv NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
Mb1794c|M.bovis_AF2122/97 NAIDGRIVEIVAELDRDGLWGVTGARSVAGLVAWKMGCSSGNAHTIATVA
MAV_4292|M.avium_104 NAIDGRIVDIVAEIDRDELCGITGARSVPALVAWKTGCSPANAHTIATIA
Mflv_1988|M.gilvum_PYR-GCK NAIDGRIVDIVAEIDGDQLWGATGARSIAALVAWKLGTSAGNAERIVAIA
Mvan_0040|M.vanbaalenii_PYR-1 NAIDGRIVEIAAQIDRDGLVGITGARSVAALVAWKTGCSPHNAKTITTVA
MSMEG_3404|M.smegmatis_MC2_155 NAIDAKIVQIVAEIDRDGLWGATGARSISALVAWKTGASERNAKAIAAVA
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 RRLASRGLGLVSAVTGQASPMQLGGTSYAEVLSRRMHMGKRAARRRIADA
MUL_2371|M.ulcerans_Agy99 RRLPAAQYALVNQLDEQPGEAELGGR-LAAVVASRLRITRSEAGRRVAEA
MMAR_0868|M.marinum_M RLQAVISHDVIAGLYTED-PAAIGGP-VTKVVADWLRITPTDARRRLRDA
Rv1765c|M.tuberculosis_H37Rv RRL------------PEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
Mb1794c|M.bovis_AF2122/97 RRL------------PEFPRCARGMREGRLSLDQVGVIAGRAGEGSDAHY
MAV_4292|M.avium_104 ARL------------PEFPRCAQGMREGWLSLDQVGVIAARGGAGSDEHY
Mflv_1988|M.gilvum_PYR-GCK DRA------------AEFPRCTQALREGRLSVDQVGVIAEGAGQGSDDHY
Mvan_0040|M.vanbaalenii_PYR-1 DRL------------EEFPRCVTALGEGRLSLDQVAVIAEHAGQGSDAHY
MSMEG_3404|M.smegmatis_MC2_155 HRA------------EEFPRCVQGLGAGRLSLDQVGVIAEGAADGSDEHY
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 ELLAPRRAITGEQLAPQLPHTAQALGRGDIGEEHLRIIRHFFDRLPVVVD
MUL_2371|M.ulcerans_Agy99 AEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPAGVD
MMAR_0868|M.marinum_M QQLSARTTLTGQVLPPELPATARAWRDGQLDGQHLRVIATFVRDLPQDTA
Rv1765c|M.tuberculosis_H37Rv AQLAGVATVNQLRTALKLEPRPEPEPDF--------------RPEPR---
Mb1794c|M.bovis_AF2122/97 AQLAGVATVNQLRTALKLEPRPEPEPDF--------------RPEPR---
MAV_4292|M.avium_104 VELARVATVSQLRTAVKLEPRPEPEP----------------QREPE---
Mflv_1988|M.gilvum_PYR-GCK ARLAQNASVSQLRTAIKQEPRPEPEPSADDGDEPDHDLPDHDEPEPPSLP
Mvan_0040|M.vanbaalenii_PYR-1 AHLAASASVSQLRTAVKSEPRPDPEPVRDPFADAD------EEPEPAPVP
MSMEG_3404|M.smegmatis_MC2_155 AALASVATVSQLRKAISLEPKPEPEP----------------KPDPR---
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 AATREAAEAQLAVMATQFRPEALRVGADRMMALLNPD-GQFSDADRARRR
MUL_2371|M.ulcerans_Agy99 VGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPD-GRHSDEDRARRR
MMAR_0868|M.marinum_M PQIVAGAEKLLAHQALQLRPDQLEKAAHRCALLINPD-GRFSDADRARQR
Rv1765c|M.tuberculosis_H37Rv -PSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDH----
Mb1794c|M.bovis_AF2122/97 -PSITRSADEQFSCWRIKLPHVEAAKFDAALQSHLDALIAEYKRDH----
MAV_4292|M.avium_104 -RAFTRTSTEQGSCYRITLAHDEAAKFDAALQSHLDALIAEWEHDR----
Mflv_1988|M.gilvum_PYR-GCK TAEITTSCDADYTYWRIKLPHEQAATFQAALHSHKDALIAQWTREH----
Mvan_0040|M.vanbaalenii_PYR-1 RPEITSTCDADYTYWRIKLPHEQSARFTAALQSHKDRLIAQHTRDHGTDP
MSMEG_3404|M.smegmatis_MC2_155 -RSIRTNPGDGYTTYHITLPRLEAAKFDTALEASHEGLIARWEREQ----
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 GITIGPQGFDGMSAISGLLDPETRAYLDAVFAKLAAPGMCNPNDQS-PLV
MUL_2371|M.ulcerans_Agy99 GLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPEDEA-AVV
MMAR_0868|M.marinum_M GFTWCAQRRDGMSIGKLIATPELRANLDAWLARFAAPGMCNPDNQT-PCV
Rv1765c|M.tuberculosis_H37Rv ----DNSDGVSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMH
Mb1794c|M.bovis_AF2122/97 ----DNSDGVSDQRPPLPGNVEAFLRLVEAGWDAEVARRPHGQHTTVVMH
MAV_4292|M.avium_104 ----DNTERVFDQRPPLPDSLDAFMRLVETGWDAEAARRPHGQHTTVVMH
Mflv_1988|M.gilvum_PYR-GCK ---ADSDEGP--HRPPLPNLAEAFLALVEASWDAEALRRPHGQHTTVVVH
Mvan_0040|M.vanbaalenii_PYR-1 TGDGDGDRGV--QLPPWPSAGEAFMELVEAGWDAEATRRPHGQHTTVVVH
MSMEG_3404|M.smegmatis_MC2_155 ----DPGDPA----VPMPDLVDAFMALVETGWDREATRRPHGQHTAVAVH
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 DGQPADDAAERDTRTVAQRHHDALRAALRSTLVSTELGSHHGLPVTVVVT
MUL_2371|M.ulcerans_Agy99 DGPVSRDAADRDSRSVSQRQHDGFNAALRAVLASGELGQHNGLPASIIVS
MMAR_0868|M.marinum_M TDEPTEDAAATDARRPAQRQHDALNALVRGQLGDPALGTHNGLPVTVIVS
Rv1765c|M.tuberculosis_H37Rv LDVQERAAGLHLGP------LLSESERRYLLCDATFEAWFERDG-QVIGC
Mb1794c|M.bovis_AF2122/97 LDVQERAAGLHLGP------LLSESERRYLLCDATFEAWFERDG-QVIGC
MAV_4292|M.avium_104 LDIAQRLAALNLGP------LLTDAERQYLTCDATCEVWFERDG-QPIGA
Mflv_1988|M.gilvum_PYR-GCK VDVESKLAALHLGP------LLTAEERRYLSCEATCEVWFERHG-RPIGA
Mvan_0040|M.vanbaalenii_PYR-1 VDIDTRVAALHLGP------LLTDEERRFLLCDATCEVWFQRHG-RPLGT
MSMEG_3404|M.smegmatis_MC2_155 VDLKSKVAALHLGP------LLGDDERRLLTCDATCEVWFELRG-RVIGT
TH_1926|M.thermoresistible__bu --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 TTLKELEDAAGIAITGAGTRLPMRDLIRMATHAHHYLAIFDDHG-RALYL
MUL_2371|M.ulcerans_Agy99 TTLKELEAAAGRGLTGGGTLLPMSDVIRLARHAHHYLAVFD-RG-EAIGL
MMAR_0868|M.marinum_M TTLQEITAATGRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSNRPLYL
Rv1765c|M.tuberculosis_H37Rv GRTTRQINRRLRRALEHRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATEL
Mb1794c|M.bovis_AF2122/97 GRTTRQINRRLRRALEHRDRTCVVPGCGAT-RGLHAHHIRHWQDGGATEL
MAV_4292|M.avium_104 GRTTRVINRRLRRALEHRHPTCAVPGCGAT-RGLHAHHLRHWEDGGPTEL
Mflv_1988|M.gilvum_PYR-GCK GRSTRTVNRRLRRALEHRDRSCVVPGCGAT-RGLHAHHIVHWEDGGDTEL
Mvan_0040|M.vanbaalenii_PYR-1 GRSTRTINRRLRRALEHRDRTCVVPGCGAT-RGLHAHHLVHWEDGGDTEL
MSMEG_3404|M.smegmatis_MC2_155 GRATRTVNRRLRRALEHRDRCCVVPGCSAT-RGLHAHHLVHWEDGGLTEM
TH_1926|M.thermoresistible__bu -----------------------VPGCGAT-RGLHAHHIRHWEHRGPTDL
MAB_0990c|M.abscessus_ATCC_199 GRSQRIASPDQRLVLHARDRGCTHPDCHVPGYLCQAHHITEWVHDGPTDI
MUL_2371|M.ulcerans_Agy99 YHAKRLATPGQRIVLYAKDRGCTRPGCDVAGYQCEVHHVAAWAISGRTDI
MMAR_0868|M.marinum_M GRTRRIASPDQRVVLYAAERGCTHPGCDAPGYWCEVHHLADWAAGGPTDV
*.* .. ..**: * * *::
Rv1765c|M.tuberculosis_H37Rv ANLVLVCPYHHRAHHRGLNRPG---ESGDSLI------------------
Mb1794c|M.bovis_AF2122/97 ANLVLVCPYHHRAHHRGLITIT---GPADNLTVADSAGRPLSAGSLARAS
MAV_4292|M.avium_104 ANLVLVCPYHHRLHHRGIITIT---GPADALTVTDSDGRPLSPGSLARPP
Mflv_1988|M.gilvum_PYR-GCK DNLVLVCPYHHRAHHRGIIVIT---GPAHQLAVTDHTGRPLQSGTLARPP
Mvan_0040|M.vanbaalenii_PYR-1 DNLVLVCPYHHRTHHRGLITIT---GPAHQLLVTDHTGRPLQPGSLARPP
MSMEG_3404|M.smegmatis_MC2_155 ANLVLLCPYHHRAHHRGLITIT---GPADQLTVTDDRGRLLTNQSLARTP
TH_1926|M.thermoresistible__bu DNLVLVCRYHHRLHHRGLITIS---DTPDNLTVSDRDGDRLHPGSLARPP
MAB_0990c|M.abscessus_ATCC_199 DNLTFACAPHHRLLGHGWTTRKRKDGTTEWIPPPQLALPG---------E
MUL_2371|M.ulcerans_Agy99 NQLTLACGPDHKLLEQGWRTRKNAHGDTEWLPPPHLDHGQPRTNSYHHPE
MMAR_0868|M.marinum_M DNLTFACTPHHRLAGKSWQTIKLPNSRTAWLPPPQLRRGAR-TNDYHHPE
:*.: * .*: :. :
Rv1765c|M.tuberculosis_H37Rv ----------------------------------------
Mb1794c|M.bovis_AF2122/97 TKPPPAVAPWPGPTGERADWWWYEPFQPQPPPISN-----
MAV_4292|M.avium_104 TQPPPAVPPCPGPLGERADWWWYDPFQPQPPPTNN-----
Mflv_1988|M.gilvum_PYR-GCK TQPPPAVPPYRGPSGERLYWKWYHPYQPPPTATAN-----
Mvan_0040|M.vanbaalenii_PYR-1 TTPPPEVNPYPGTSGERAQWKWYHPYQPPPPTSNN-----
MSMEG_3404|M.smegmatis_MC2_155 TTPPPTVPPCPGPLGERAQWWWYQPFEPQPPPSAN-----
TH_1926|M.thermoresistible__bu DRPPPQVAPCTGPTGERADWWWYTPYQPPAPPPADETGPG
MAB_0990c|M.abscessus_ATCC_199 TRHDDIVDQCPHGVGSR-----------------------
MUL_2371|M.ulcerans_Agy99 KLLRDSADDDDEGHGAA-----------------------
MMAR_0868|M.marinum_M RLLDDRAAPD------------------------------