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VNNRPIRLLTSGRAGLGAGALITAVVLLIALGAVWTPVAFADGCPDAEVTFARGTGEPPGIGRVGQAFVD SLRQQTGMEIGVYPVNYAASRLQLHGGDGANDAISHIKSMASSCPNTKLVLGGYSQGATVIDIVAGVPLG SISFGSPLPAAYADNVAAVAVFGNPSNRAGGSLSSLSPLFGSKAIDLCNPTDPICHVGPGNEFSGHIDGY IPTYTTQAASFVVQRLRAGSVPHLPGSVPQLPGSVLQMPGTAAPAPESLHGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv3451 | cut3 | - | 100% (262) | PROBABLE CUTINASE PRECURSOR CUT3 |
| M. tuberculosis H37Rv | Rv3452 | cut4 | 8e-62 | 56.76% (222) | cutinase precursor CUT4 |
| M. tuberculosis H37Rv | Rv2301 | cut2 | 3e-42 | 42.29% (227) | cutinase CUT2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3481 | cut3 | 1e-151 | 100.00% (262) | cutinase precursor CUT3 |
| M. gilvum PYR-GCK | Mflv_4965 | - | 1e-47 | 45.29% (223) | cutinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3766 | - | 3e-51 | 46.85% (222) | cutinase cut3 precursor |
| M. marinum M | MMAR_1098 | cut3 | 2e-96 | 68.58% (261) | cutinase precursor, Cut3 |
| M. avium 104 | MAV_4394 | - | 5e-83 | 63.79% (243) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_2095 | - | 1e-74 | 61.40% (228) | serine esterase, cutinase family protein |
| M. thermoresistible (build 8) | TH_4127 | - | 7e-40 | 50.58% (172) | PUTATIVE serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_0856 | cut3 | 2e-95 | 67.82% (261) | cutinase precursor, Cut3 |
| M. vanbaalenii PYR-1 | Mvan_1441 | - | 5e-53 | 51.64% (213) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv3451|M.tuberculosis_H37Rv MNNRPIRLLTSGRAGLGAGALITAVVLL----IALGA-VWT--PVAFADG
Mb3481|M.bovis_AF2122/97 MNNRPIRLLTSGRAGLGAGALITAVVLL----IALGA-VWT--PVAFADG
MMAR_1098|M.marinum_M MNKHPLAVL--------AGALVTATGLL----AAPSI-TGTAIPSASAAD
MUL_0856|M.ulcerans_Agy99 MNKHPLAVL--------AGALVTATGLL----AAPSI-TGTAIPSASAAD
MAV_4394|M.avium_104 MKTHRIGRL----LGLGSSALITAAGLL----GAP-----AAVPVASADD
MSMEG_2095|M.smegmatis_MC2_155 MLSRRIG----------AWALMAAGIAL----VVP-----ARLPVASAAE
MAB_3766|M.abscessus_ATCC_1997 MTTHQRGTRVG--VVLSSFVVLTVLVLS----AASVVGPVSAVPRASADP
Mflv_4965|M.gilvum_PYR-GCK MKIDLEVVTRG------VRALVAAAVAAGVLVVAPAVAAPRSLPAAGAQG
Mvan_1441|M.vanbaalenii_PYR-1 MMIDLDAPARR------ATGVLAAILVA----AATLVAAPVQIPAAHAQG
TH_4127|M.thermoresistible__bu --------VLG------SAALLAG------------VPAP----TAAAIP
::: * *
Rv3451|M.tuberculosis_H37Rv CPDAEVTFARGTGEPPGIGRVGQAFVDSL--RQQT-GMEIGVYPVNYAAS
Mb3481|M.bovis_AF2122/97 CPDAEVTFARGTGEPPGIGRVGQAFVDSL--RQQT-GMEIGVYPVNYAAS
MMAR_1098|M.marinum_M CPDAEVVFARGTSEPPGIGRVGEAFVDSL--RQQT-GKNIGVYAVNYPAS
MUL_0856|M.ulcerans_Agy99 CPDAEVVFPRGTSEPPGIGRVGEAFVDSL--RQQT-GKNIGVYAVNYPAS
MAV_4394|M.avium_104 CPDVEVIFARGTNEPPGMGRVGDAFVESL--RQQTSGLNIDTYGVNYAAS
MSMEG_2095|M.smegmatis_MC2_155 CPDAEVVFARGTDEPAGLGRVGTAFVDAL--RKQAAGLEIDAYAVDYKAG
MAB_3766|M.abscessus_ATCC_1997 CSDVDVSFARGRKEPVGLGRVGDEFVDSLTPRVQATGATMNVYPVNYDAG
Mflv_4965|M.gilvum_PYR-GCK CTDIQVVFARGTDEPPGLGRVGSAFVESL--RGRVGGRSVGSYAVAYPAT
Mvan_1441|M.vanbaalenii_PYR-1 CPDIEVVFARGTDEPPGLGRVGAAFVDSL--RGRVGGRSVGTYAVNYPAS
TH_4127|M.thermoresistible__bu CSDVEVVFARGTSEPPGVGRVGQALANAL--QARLPGRTVSTYGVSYPAT
*.* :* *.** ** *:**** :.::* : : * :. * * * *
Rv3451|M.tuberculosis_H37Rv RLQLHGGDGANDAISHIKSMASSCPNTKLVLGGYSQGATVIDIVAGVPLG
Mb3481|M.bovis_AF2122/97 RLQLHGGDGANDAISHIKSMASSCPNTKLVLGGYSQGATVIDIVAGVPLG
MMAR_1098|M.marinum_M RLQLHGGDGANDVISHVKSMASSCPNTKIVLGGYSQGADVIDIVAGVPLA
MUL_0856|M.ulcerans_Agy99 RLQLHGGDGANDVISHVKSMASSCPNTKIVQGGYSQGADVIDIVAGVPLA
MAV_4394|M.avium_104 KLQLHGGDGANDTINRIKQAVQKCPNTKIVLGGYSQGASVMDIVAGVPIG
MSMEG_2095|M.smegmatis_MC2_155 KLQLSGGDGAKDAIAHIKSTVSSCSNTKIVLGGYSQGASVVNIAAGNQLG
MAB_3766|M.abscessus_ATCC_1997 --IFSAGGGANDLSNHLQSVAASCPRTKLVIGGYSMGAEVIDTIIGVPNV
Mflv_4965|M.gilvum_PYR-GCK FDFLAAAGGANDASNHIQWMMANCPSTRLVLGGYSQGAAVIDVIAAVPFP
Mvan_1441|M.vanbaalenii_PYR-1 FDFLAAAAGANDASLHIQYMMANCPRTRLVLGGYSQGAAVIDVIAAVPIP
TH_4127|M.thermoresistible__bu YDFLAATDGANDATARITTLAQQCPSTRVVLGGYSQGAAVVDMLGGLPPL
: . **:* :: .*. *::* **** ** *:: .
Rv3451|M.tuberculosis_H37Rv S--ISFG-SPLPAAYADNVAAVAVFGNPSNRAGGSLSSLSPLFGSKAIDL
Mb3481|M.bovis_AF2122/97 S--ISFG-SPLPAAYADNVAAVAVFGNPSNRAGGSLSSLSPLFGSKAIDL
MMAR_1098|M.marinum_M G--ISFG-NELPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGSKSIDL
MUL_0856|M.ulcerans_Agy99 G--ISFG-NELPAQYADNIAAVAVFGNVANRSGGSLTTQSSLLGSKSIDL
MAV_4394|M.avium_104 G--INWG-SSITPDLASHVAAVATFGDVADRAGGTLPSQSALLGSKAIDL
MSMEG_2095|M.smegmatis_MC2_155 G--ITWA-DPLPAQYANNVAAIVTFGDIATRTGEALSTRSNLFGSKAIDL
MAB_3766|M.abscessus_ATCC_1997 G--IGFN-RPLPPTVGDRIVAIATFGNATHRTGGPLSGIAGVFGSRAIDL
Mflv_4965|M.gilvum_PYR-GCK --AVGFD-RPLPPNAPDFIAAIALFGNPTTKVGLPIT-ASPVWGTRSIDL
Mvan_1441|M.vanbaalenii_PYR-1 --AVGFN-APLPPNTPDFVAAIAVFGNPSTKLGIPIT-ASPVWGSRSIDL
TH_4127|M.thermoresistible__bu GDRVGLVGSALPTGSVGNVAAVAVFGNPSAKFGRPIN-TSPVFGGRGIDL
: :.. . :.*:. **: : : * .: : : * :.***
Rv3451|M.tuberculosis_H37Rv CNPTDPICHVGPGNEFSGHIDGYIPTYTTQAASFVVQRLRAGSVP-----
Mb3481|M.bovis_AF2122/97 CNPTDPICHVGPGNEFSGHIDGYIPTYTTQAASFVVQRLRAGSVP-----
MMAR_1098|M.marinum_M CNPSDPICHSGPGNDWNGHTDGYVPTYTTQAASFVAAKLAASSMAPV---
MUL_0856|M.ulcerans_Agy99 CNPSDPICHSGPGNDWNGHTDGYVPTYTTQAASFVAAKLAASSMAPV---
MAV_4394|M.avium_104 CNPNDPICHAGPGNEWSGHTEGYVPVYTTQAAAFVASKL-MGAGQSVPGY
MSMEG_2095|M.smegmatis_MC2_155 CNPSDPICHAGQGNEWSGHTDGYVPVYTTQAAVFAAAKLRAGSGRSVPGY
MAB_3766|M.abscessus_ATCC_1997 CNQGDPICMAGPNNSWDAHTSYERTGLPAEAAAFVASKLNRHGESEAE--
Mflv_4965|M.gilvum_PYR-GCK CNGADPVCSAG--DDIAAHSNYGPAGFTDQAAAFVAGLV-----------
Mvan_1441|M.vanbaalenii_PYR-1 CNGLDPVCSGG--DDIAAHSNYGPGMFTDQAAAFVAGRL-----------
TH_4127|M.thermoresistible__bu CSDGDPICSNG--RNPFAHTNYETSVHIETAADFAAGLI-----------
*. **:* * . .* . ** *.. :
Rv3451|M.tuberculosis_H37Rv -----------------------------HLPGSVP------QLPGSVLQ
Mb3481|M.bovis_AF2122/97 -----------------------------HLPGSVP------QLPGSVLQ
MMAR_1098|M.marinum_M ----------------------------VQLPGPVP------RAPGPAPQ
MUL_0856|M.ulcerans_Agy99 ----------------------------VRLPGPVP------RAPGPAPQ
MAV_4394|M.avium_104 GPSVPGAGP-QSPGYGQQS-----PVYGQTPPGSGPSIHDNAPGPGTAPA
MSMEG_2095|M.smegmatis_MC2_155 G-TVPEYGPGYGPGYGSGNGQGYGPLYGPATPGYDPESPTHGPPPGYVPA
MAB_3766|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_4965|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1441|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4127|M.thermoresistible__bu --------------------------------------------------
Rv3451|M.tuberculosis_H37Rv MPG--TAAP-----APESLHGR----------
Mb3481|M.bovis_AF2122/97 MPG--TAAP-----APESLHGR----------
MMAR_1098|M.marinum_M APGPATASPGTPVGATGTLVGAH---------
MUL_0856|M.ulcerans_Agy99 APGPATASPGTPVGATGTLVGAH---------
MAV_4394|M.avium_104 PA--VPSTP------PSQAP------LV----
MSMEG_2095|M.smegmatis_MC2_155 PPGYVPETPGYELPGPSAAEPSAEVGLVSAVG
MAB_3766|M.abscessus_ATCC_1997 --------------------------------
Mflv_4965|M.gilvum_PYR-GCK --------------------------------
Mvan_1441|M.vanbaalenii_PYR-1 --------------------------------
TH_4127|M.thermoresistible__bu --------------------------------