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IARSFARILGAAVVALGVLSAPVFSPSATADPCSDVAVVFARGTHQEPGLGNIGQAFVDSLTSQVGGRSV DVYAVNYPANDDYHTSASLGSDDASAHIQGTVANCPNTKIVLGGYSQGATVIDLASTAMPSTVADHVAAV ALFGEPSSGFSSMLWGGQPLPTINPLYGAKTINLCAADDPICTGGGNIMAHVSYIQAGMTDQAASFAAGK LN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2934 | cfp21 | - | 100% (213) | cutinase Cfp21 |
| M. marinum M | MMAR_3837 | - | 3e-56 | 50.43% (232) | cutinase precursor |
| M. marinum M | MMAR_2419 | cut1 | 6e-50 | 48.48% (231) | cutinase Cut1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2006c | cfp21 | 4e-91 | 75.70% (214) | cutinase precursor CFP21 |
| M. gilvum PYR-GCK | Mflv_4965 | - | 2e-49 | 48.40% (219) | cutinase |
| M. tuberculosis H37Rv | Rv1984c | cfp21 | 4e-91 | 75.70% (214) | cutinase precursor CFP21 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3272c | - | 2e-40 | 46.84% (190) | cutinase Cut1 |
| M. avium 104 | MAV_2741 | - | 5e-92 | 83.68% (190) | serine esterase, cutinase family protein |
| M. smegmatis MC2 155 | MSMEG_1528 | - | 3e-48 | 45.41% (229) | cutinase |
| M. thermoresistible (build 8) | TH_0238 | - | 3e-46 | 45.37% (227) | serine esterase, cutinase family protein |
| M. ulcerans Agy99 | MUL_1597 | cut1 | 3e-46 | 48.76% (201) | cutinase Cut1 |
| M. vanbaalenii PYR-1 | Mvan_3105 | - | 3e-57 | 51.79% (224) | cutinase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2934|M.marinum_M ------MIAR------SFARILGAAVVA-LGVLSAPVFSPSATADPCSDV
MAV_2741|M.avium_104 ---------------------MG---------------NPVAAADPCSDV
Mb2006c|M.bovis_AF2122/97 ------MTPR------SLVRIVGVVVATTLALVSAPAGGRAAHADPCSDI
Rv1984c|M.tuberculosis_H37Rv ------MTPR------SLVRIVGVVVATTLALVSAPAGGRAAHADPCSDI
Mflv_4965|M.gilvum_PYR-GCK MKIDLEVVTRGVRALVAAAVAAGVLVVAP-AVAAPR-SLPAAGAQGCTDI
MSMEG_1528|M.smegmatis_MC2_155 --MSLDLVFRRARLVAAAALIATVMLAAPLAAHAPTGALGAARAADCPDI
Mvan_3105|M.vanbaalenii_PYR-1 ------MQVRRVLGIVGAAVAVSAG-LWPIGVGAPA-----ASADPCPDI
TH_0238|M.thermoresistible__bu ------LSRIGSAVGAALTTASLITGTVITSTVVAGTAVPAAAAQPCPDV
MUL_1597|M.ulcerans_Agy99 --------------------------------MFSAVAIPSASAEPCPDV
MAB_3272c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_2934|M.marinum_M AVVFARGTHQEPGLGNIGQAFVDSLTSQVGGRSVDVYAVNYPANDDYHTS
MAV_2741|M.avium_104 SVVFARGTHQEPGLGNIGQAFVDSLTSQLGGRSVDVYAVNYPANDDYHNS
Mb2006c|M.bovis_AF2122/97 AVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGVYAVNYPASDDYRAS
Rv1984c|M.tuberculosis_H37Rv AVVFARGTHQASGLGDVGEAFVDSLTSQVGGRSIGVYAVNYPASDDYRAS
Mflv_4965|M.gilvum_PYR-GCK QVVFARGTDEPPGLGRVGSAFVESLRGRVGGRSVGSYAVAYPATFDFLAA
MSMEG_1528|M.smegmatis_MC2_155 EVVFARGTDESPGIGRIGNAFVQALRGKVGGRSVGTYAVNYPASYDFLAA
Mvan_3105|M.vanbaalenii_PYR-1 EVIFARGTGAEPGLGWVGDAFVNALRPKVGGRSVGTYAVNYPAGFDFDNS
TH_0238|M.thermoresistible__bu QVVFARGTGEPPGVGPTGQAFIDALRPRVGDRSLDVYAVNYPAIDVWNTG
MUL_1597|M.ulcerans_Agy99 EVVFARGTGEPPGLGPTGQAFVNSLRSHIGGRSLDVYPVNYPASDNWDTG
MAB_3272c|M.abscessus_ATCC_199 --MFARGTFEPPGVGGTGESFVNALRARTKGKSVEVYPVEYPASLAFATA
:***** .*:* *.:*:::* : .:*: *.* *** : .
MMAR_2934|M.marinum_M ASLGSDDASAHIQGTVANCPNTKIVLGGYSQGATVIDLAST---------
MAV_2741|M.avium_104 ANAGADDASAHVQDTVAACPNSRIVLGGYSQGSTVIDLATN---------
Mb2006c|M.bovis_AF2122/97 ASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTS---------
Rv1984c|M.tuberculosis_H37Rv ASNGSDDASAHIQRTVASCPNTRIVLGGYSQGATVIDLSTS---------
Mflv_4965|M.gilvum_PYR-GCK AG-GANDASNHIQWMMANCPSTRLVLGGYSQGAAVIDVIAAVPFPA---V
MSMEG_1528|M.smegmatis_MC2_155 AD-GANDASGHVQWMVNNCPNTRLVLGGYSQGAAVIDVIAAVPFPA---I
Mvan_3105|M.vanbaalenii_PYR-1 APLGAADASGRVQWMAGNCPDTKLVLGGMSQGAGVIDLITVDPRPL---G
TH_0238|M.thermoresistible__bu ID-GIRDAGAHVVRMAEQCPDTRLVLGGFSQGAAVMGFVTSAEVPAGVDP
MUL_1597|M.ulcerans_Agy99 LD-GIRDAGTHVVSMAGQCPQTKMVLGGYSQGTAVMSFVTSAAVPAGVDP
MAB_3272c|M.abscessus_ATCC_199 AD-GVIDASNRVKDVAARCPNTKIVMGGFSQGAAVVAYTTADAVPPGFEL
* **. :: **.:::*:** ***: *: :
MMAR_2934|M.marinum_M ------AMPSTVADHVAAVALFGEPSSGFSSMLWGGQPLPTINPLYGAKT
MAV_2741|M.avium_104 ------AMPPSVADHVAAVALFGEPSSGFSTMLWGGQPLPTINPLYGGKT
Mb2006c|M.bovis_AF2122/97 ------AMPPAVADHVAAVALFGEPSSGFSSMLWGGGSLPTIGPLYSSKT
Rv1984c|M.tuberculosis_H37Rv ------AMPPAVADHVAAVALFGEPSSGFSSMLWGGGSLPTIGPLYSSKT
Mflv_4965|M.gilvum_PYR-GCK GF-D-RPLPPNAPDFIAAIALFGNPT------TKVGLPITASP-VWGTRS
MSMEG_1528|M.smegmatis_MC2_155 GF-N-APLPANVPEHVAAVAVFGNPS------AKLGLPLTASP-VYGSRA
Mvan_3105|M.vanbaalenii_PYR-1 RF-TPTPMPPNVADHVAAVVVFGNPLR----DIRGGGPLPQMSGTYGSKS
TH_0238|M.thermoresistible__bu AT-VPKPLDPDIAEHVAAVVLFGMPNAR--AMNFLGTPPVVIGPLYEDKT
MUL_1597|M.ulcerans_Agy99 AT-VPKPLQPDVAEHVAAVVLFGMPNVR--AMNFLGEPAVEIGPAYQAKT
MAB_3272c|M.abscessus_ATCC_199 PEGITGPMPAEVADHVAAVALFGKPSSGFLQRIDNTAPPINIGHLYVAKT
.: . .:.:**:.:** * . : ::
MMAR_2934|M.marinum_M INLCAADDPICT-GGGNIMAHVSYIQ-AGMTDQAASFAAGKLN-------
MAV_2741|M.avium_104 ISLCAPDDPICS-GGGNIMAHVSYID-AGMTAHAATFAANHLNQGSPRT-
Mb2006c|M.bovis_AF2122/97 INLCAPDDPICT-GGGNIMAHVSYVQ-SGMTSQAATFAANRLDHAG----
Rv1984c|M.tuberculosis_H37Rv INLCAPDDPICT-GGGNIMAHVSYVQ-SGMTSQAATFAANRLDHAG----
Mflv_4965|M.gilvum_PYR-GCK IDLCNGADPVCS-AGDDIAAHSNYGP-AGFTDQAAAFVAGLV--------
MSMEG_1528|M.smegmatis_MC2_155 IDLCNAGDPVCG-SGDSVPAHRAYD--GGPANQAAAFVAGLL--------
Mvan_3105|M.vanbaalenii_PYR-1 IDLCAFDDPFCS-PGFNLPAHFAYVD-NGMVEEAANFAAGRLG-------
TH_0238|M.thermoresistible__bu VKLCAVDDPVCS-NGMNFAAHNTYATNAAMVDQGAAFAADRLGVASDKPL
MUL_1597|M.ulcerans_Agy99 IKVCVPEDPVCS-DGLNFAAHNAYADDGAVVDQGVAFAASRLGGDPGGPV
MAB_3272c|M.abscessus_ATCC_199 MDMCVPEDPICSPDGSDNAAHGSYGD-NGMTSQAADFAARQINSPTDTVS
:.:* **.* * . ** * . . ... *.* :
MMAR_2934|M.marinum_M -----------
MAV_2741|M.avium_104 -----------
Mb2006c|M.bovis_AF2122/97 -----------
Rv1984c|M.tuberculosis_H37Rv -----------
Mflv_4965|M.gilvum_PYR-GCK -----------
MSMEG_1528|M.smegmatis_MC2_155 -----------
Mvan_3105|M.vanbaalenii_PYR-1 -----------
TH_0238|M.thermoresistible__bu PTPSSGQNFGN
MUL_1597|M.ulcerans_Agy99 PAPSSG--FGN
MAB_3272c|M.abscessus_ATCC_199 AAG--------